MX2009001067A - Formas cristalinas de analogos de rapamicina. - Google Patents
Formas cristalinas de analogos de rapamicina.Info
- Publication number
- MX2009001067A MX2009001067A MX2009001067A MX2009001067A MX2009001067A MX 2009001067 A MX2009001067 A MX 2009001067A MX 2009001067 A MX2009001067 A MX 2009001067A MX 2009001067 A MX2009001067 A MX 2009001067A MX 2009001067 A MX2009001067 A MX 2009001067A
- Authority
- MX
- Mexico
- Prior art keywords
- crystalline forms
- rapamycin analogs
- rapamycin analog
- formula
- rapamycin
- Prior art date
Links
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical class C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 title abstract 4
- 239000013078 crystal Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
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- Pulmonology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
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- Toxicology (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82031706P | 2006-07-25 | 2006-07-25 | |
| US11/781,807 US7820812B2 (en) | 2006-07-25 | 2007-07-23 | Methods of manufacturing crystalline forms of rapamycin analogs |
| US11/781,804 US7812032B2 (en) | 2006-07-25 | 2007-07-23 | Crystalline forms of rapamycin analogs |
| PCT/US2007/074159 WO2008014222A1 (en) | 2006-07-25 | 2007-07-24 | Crystalline forms of rapamycin analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009001067A true MX2009001067A (es) | 2009-06-17 |
Family
ID=38562825
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009001067A MX2009001067A (es) | 2006-07-25 | 2007-07-24 | Formas cristalinas de analogos de rapamicina. |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP2051984A1 (enExample) |
| JP (1) | JP2010500286A (enExample) |
| KR (1) | KR20090035716A (enExample) |
| AU (1) | AU2007276837B2 (enExample) |
| BR (1) | BRPI0714945B8 (enExample) |
| CA (1) | CA2658896A1 (enExample) |
| IL (1) | IL196706A0 (enExample) |
| MX (1) | MX2009001067A (enExample) |
| NZ (1) | NZ574654A (enExample) |
| WO (1) | WO2008014222A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7812032B2 (en) | 2006-07-25 | 2010-10-12 | Abbott Laboratories | Crystalline forms of rapamycin analogs |
| US7820812B2 (en) | 2006-07-25 | 2010-10-26 | Abbott Laboratories | Methods of manufacturing crystalline forms of rapamycin analogs |
| KR20120106880A (ko) | 2007-01-21 | 2012-09-26 | 헤모텍 아게 | 체강의 협착 치료 및 급성 재협착 예방을 위한 의료 제품 |
| US9192697B2 (en) | 2007-07-03 | 2015-11-24 | Hemoteq Ag | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis |
| JP5643770B2 (ja) * | 2009-01-21 | 2014-12-17 | バイオコン・リミテッドBiocon Limited | シロリムスの安定性の決定方法およびその安定形態の調製方法 |
| EP2451496B1 (en) | 2009-07-10 | 2015-07-22 | Boston Scientific Scimed, Inc. | Use of nanocrystals for a drug delivery balloon |
| WO2011008393A2 (en) | 2009-07-17 | 2011-01-20 | Boston Scientific Scimed, Inc. | Nucleation of drug delivery balloons to provide improved crystal size and density |
| WO2012031236A1 (en) | 2010-09-02 | 2012-03-08 | Boston Scientific Scimed, Inc. | Coating process for drug delivery balloons using heat-induced rewrap memory |
| US8669360B2 (en) | 2011-08-05 | 2014-03-11 | Boston Scientific Scimed, Inc. | Methods of converting amorphous drug substance into crystalline form |
| US9056152B2 (en) | 2011-08-25 | 2015-06-16 | Boston Scientific Scimed, Inc. | Medical device with crystalline drug coating |
| US9439892B2 (en) | 2013-05-16 | 2016-09-13 | Surmodics, Inc. | Macrolide particulates, methods for preparation, and medical devices associated therewith |
| US9770537B2 (en) | 2013-06-12 | 2017-09-26 | Surmodics, Inc. | Solvent methods for preparing crystalline macrolide particulates, compositions, and articles containing particulates |
| DE102013110294B4 (de) * | 2013-09-18 | 2016-07-07 | Innora Gmbh | Limus-Depot-Formulierung auf Ballonkathetern |
| US10098846B2 (en) | 2016-03-31 | 2018-10-16 | Surmodics, Inc. | Drug-containing particulate composition with cationic agent, associated medical devices, and methods for treatment |
| US11123459B2 (en) | 2016-12-16 | 2021-09-21 | Surmodics, Inc. | Hydrophobic active agent particle coatings and methods for treatment |
| CN108144131A (zh) * | 2017-12-22 | 2018-06-12 | 上海微创医疗器械(集团)有限公司 | 一种载药植入医疗器械及其制备方法 |
| JP2023519875A (ja) * | 2020-03-27 | 2023-05-15 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 薬品の結晶化のための方法 |
| EP4281463A4 (en) * | 2021-01-22 | 2025-07-23 | Janssen Pharmaceutica Nv | RAPAMYCIN ANALOGUES AND THEIR USES |
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| US5527907A (en) | 1993-11-19 | 1996-06-18 | Abbott Laboratories | Macrolide immunomodulators |
| US6015815A (en) * | 1997-09-26 | 2000-01-18 | Abbott Laboratories | Tetrazole-containing rapamycin analogs with shortened half-lives |
| US20030129215A1 (en) * | 1998-09-24 | 2003-07-10 | T-Ram, Inc. | Medical devices containing rapamycin analogs |
| TW557297B (en) * | 1997-09-26 | 2003-10-11 | Abbott Lab | Rapamycin analogs having immunomodulatory activity, and pharmaceutical compositions containing same |
| SK9742002A3 (en) * | 2000-01-07 | 2003-02-04 | Transform Pharmaceuticals Inc | High-throughput formation, identification, and analysis of diverse solid-forms |
| AR050374A1 (es) * | 2004-08-20 | 2006-10-18 | Wyeth Corp | Forma polimorfica de rafampicina |
| TW200628483A (en) * | 2004-12-01 | 2006-08-16 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Processes for producing crystalline macrolides |
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2007
- 2007-07-24 AU AU2007276837A patent/AU2007276837B2/en active Active
- 2007-07-24 EP EP07799771A patent/EP2051984A1/en not_active Withdrawn
- 2007-07-24 CA CA002658896A patent/CA2658896A1/en not_active Abandoned
- 2007-07-24 JP JP2009521936A patent/JP2010500286A/ja active Pending
- 2007-07-24 WO PCT/US2007/074159 patent/WO2008014222A1/en not_active Ceased
- 2007-07-24 EP EP11183446A patent/EP2407471A3/en not_active Withdrawn
- 2007-07-24 MX MX2009001067A patent/MX2009001067A/es active IP Right Grant
- 2007-07-24 NZ NZ574654A patent/NZ574654A/en unknown
- 2007-07-24 KR KR1020097003955A patent/KR20090035716A/ko not_active Ceased
- 2007-07-24 BR BRPI0714945A patent/BRPI0714945B8/pt active IP Right Grant
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2009
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| WO2008014222A1 (en) | 2008-01-31 |
| AU2007276837A1 (en) | 2008-01-31 |
| EP2407471A2 (en) | 2012-01-18 |
| BRPI0714945B1 (pt) | 2020-11-10 |
| EP2051984A1 (en) | 2009-04-29 |
| CA2658896A1 (en) | 2008-01-31 |
| BRPI0714945A2 (pt) | 2013-05-21 |
| IL196706A0 (en) | 2009-11-18 |
| AU2007276837B2 (en) | 2013-02-07 |
| KR20090035716A (ko) | 2009-04-10 |
| JP2010500286A (ja) | 2010-01-07 |
| NZ574654A (en) | 2012-03-30 |
| EP2407471A3 (en) | 2012-06-20 |
| BRPI0714945B8 (pt) | 2021-05-25 |
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