BRPI0714945B8 - composições de análogo de rapamicina e processos para preparação de formas cristalinas de análogos de rapamicinas - Google Patents

composições de análogo de rapamicina e processos para preparação de formas cristalinas de análogos de rapamicinas

Info

Publication number
BRPI0714945B8
BRPI0714945B8 BRPI0714945A BRPI0714945A BRPI0714945B8 BR PI0714945 B8 BRPI0714945 B8 BR PI0714945B8 BR PI0714945 A BRPI0714945 A BR PI0714945A BR PI0714945 A BRPI0714945 A BR PI0714945A BR PI0714945 B8 BRPI0714945 B8 BR PI0714945B8
Authority
BR
Brazil
Prior art keywords
rapamycin
crystalline forms
processes
analogues
preparing crystalline
Prior art date
Application number
BRPI0714945A
Other languages
English (en)
Inventor
Zhang Geoff
Bartelt Larry
Dhaon Madhup
Rasmussen Michael
Leanna Robert
Henry Rodger
Viswanath Shekhar
Chen Shuang
Borchardt Thomas
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/781,804 external-priority patent/US7812032B2/en
Priority claimed from US11/781,807 external-priority patent/US7820812B2/en
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BRPI0714945A2 publication Critical patent/BRPI0714945A2/pt
Publication of BRPI0714945B1 publication Critical patent/BRPI0714945B1/pt
Publication of BRPI0714945B8 publication Critical patent/BRPI0714945B8/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
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    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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Abstract

formas cristalinas de análogos de rapamicinas. uma composição de análogo de rapamicina inclui uma forma cristalina de um análogo de rapamicina. o cristal pode ser um hidrato, deididrato, solvato, ou dessolvado. o análogo de rapamicina pode possuir uma estrutura de fórmula 1, a qual é opicionalmente um pró-fármaco, sal, derivado, ou combinação dos mesmos.
BRPI0714945A 2006-07-25 2007-07-24 composições de análogo de rapamicina e processos para preparação de formas cristalinas de análogos de rapamicinas BRPI0714945B8 (pt)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US82031706P 2006-07-25 2006-07-25
US60/820,317 2006-07-25
US60/820.317 2006-07-25
US11/781,814 2007-07-23
US11/781,804 US7812032B2 (en) 2006-07-25 2007-07-23 Crystalline forms of rapamycin analogs
US11/781,807 2007-07-23
US11/781.807 2007-07-23
US11/781,807 US7820812B2 (en) 2006-07-25 2007-07-23 Methods of manufacturing crystalline forms of rapamycin analogs
US11/781.804 2007-07-23
PCT/US2007/074159 WO2008014222A1 (en) 2006-07-25 2007-07-24 Crystalline forms of rapamycin analogs

Publications (3)

Publication Number Publication Date
BRPI0714945A2 BRPI0714945A2 (pt) 2013-05-21
BRPI0714945B1 BRPI0714945B1 (pt) 2020-11-10
BRPI0714945B8 true BRPI0714945B8 (pt) 2021-05-25

Family

ID=38562825

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0714945A BRPI0714945B8 (pt) 2006-07-25 2007-07-24 composições de análogo de rapamicina e processos para preparação de formas cristalinas de análogos de rapamicinas

Country Status (10)

Country Link
EP (2) EP2051984A1 (pt)
JP (1) JP2010500286A (pt)
KR (1) KR20090035716A (pt)
AU (1) AU2007276837B2 (pt)
BR (1) BRPI0714945B8 (pt)
CA (1) CA2658896A1 (pt)
IL (1) IL196706A0 (pt)
MX (1) MX2009001067A (pt)
NZ (1) NZ574654A (pt)
WO (1) WO2008014222A1 (pt)

Families Citing this family (16)

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US7812032B2 (en) 2006-07-25 2010-10-12 Abbott Laboratories Crystalline forms of rapamycin analogs
US7820812B2 (en) 2006-07-25 2010-10-26 Abbott Laboratories Methods of manufacturing crystalline forms of rapamycin analogs
EP2269664B1 (de) 2007-01-21 2012-08-22 Hemoteq AG Medizinprodukt zur Behandlung von Verschlüssen von Körperdurchgängen und zur Prävention drohender Wiederverschlüsse
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
JP5643770B2 (ja) * 2009-01-21 2014-12-17 バイオコン・リミテッドＢｉｏｃｏｎ Ｌｉｍｉｔｅｄ シロリムスの安定性の決定方法およびその安定形態の調製方法
US10369256B2 (en) 2009-07-10 2019-08-06 Boston Scientific Scimed, Inc. Use of nanocrystals for drug delivery from a balloon
EP2962707B1 (en) 2009-07-17 2019-07-24 Boston Scientific Scimed, Inc. Drug delivery balloons with improved crystal size and density
EP2611476B1 (en) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
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