MX2008008556A - Derivados de triterpenoquinonas y triterpenofenoles y su aplicacion para el tratamiento de tumores y enfermedades parasitarias. - Google Patents

Derivados de triterpenoquinonas y triterpenofenoles y su aplicacion para el tratamiento de tumores y enfermedades parasitarias.

Info

Publication number
MX2008008556A
MX2008008556A MX2008008556A MX2008008556A MX2008008556A MX 2008008556 A MX2008008556 A MX 2008008556A MX 2008008556 A MX2008008556 A MX 2008008556A MX 2008008556 A MX2008008556 A MX 2008008556A MX 2008008556 A MX2008008556 A MX 2008008556A
Authority
MX
Mexico
Prior art keywords
triterpenequinone
triterpenephenol
tumors
derivatives
treatment
Prior art date
Application number
MX2008008556A
Other languages
English (en)
Spanish (es)
Inventor
Juan Carlos Lacal San Juan
Original Assignee
Consejo Superior Investigacion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior Investigacion filed Critical Consejo Superior Investigacion
Publication of MX2008008556A publication Critical patent/MX2008008556A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C07C49/727—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/753—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
MX2008008556A 2005-12-30 2006-12-29 Derivados de triterpenoquinonas y triterpenofenoles y su aplicacion para el tratamiento de tumores y enfermedades parasitarias. MX2008008556A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200503263A ES2277568B1 (es) 2005-12-30 2005-12-30 Derivados de triterpenoquinona y triterpenofenoles y su aplicacion para el tratamiento de tumores y enfermedades parasitarias.
PCT/EP2006/070276 WO2007077203A2 (fr) 2005-12-30 2006-12-29 Derives de triterpenequinone et de triterpenephenol et leur application pour le traitement de tumeurs et de maladies parasitaires

Publications (1)

Publication Number Publication Date
MX2008008556A true MX2008008556A (es) 2008-09-26

Family

ID=37946257

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008008556A MX2008008556A (es) 2005-12-30 2006-12-29 Derivados de triterpenoquinonas y triterpenofenoles y su aplicacion para el tratamiento de tumores y enfermedades parasitarias.

Country Status (11)

Country Link
EP (1) EP1976533A2 (fr)
JP (1) JP2009522239A (fr)
KR (1) KR20080083044A (fr)
CN (1) CN101351211A (fr)
AU (1) AU2006334359A1 (fr)
BR (1) BRPI0620845A2 (fr)
CA (1) CA2635318A1 (fr)
ES (1) ES2277568B1 (fr)
MX (1) MX2008008556A (fr)
RU (1) RU2008131311A (fr)
WO (1) WO2007077203A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4759612B2 (ja) 2005-04-13 2011-08-31 コンセホ スペリオール デ インベスティガシオネス シエンティフィカス 癌治療化合物のｉｎ ｖｉｔｒｏにおける同定方法
US7776894B2 (en) 2007-08-17 2010-08-17 Burnham Institute For Medical Research Compositions and methods for inhibiting growth and metastasis of melanoma
CN101434635B (zh) * 2007-11-16 2012-05-16 上海华拓医药科技发展股份有限公司 一类具抗肿瘤活性的水溶性酚性三萜化合物及其制备方法
US20100068302A1 (en) * 2008-09-17 2010-03-18 Traslational Cancer Drugs Pharma, S.L. Methods and compositions for the treatment of cancer
WO2010049173A1 (fr) * 2008-10-31 2010-05-06 Cenix Bioscience Gmbh Utilisation d’inhibiteurs de kinases hôtes pour traiter les maladies infectieuses
US8691977B2 (en) * 2010-08-23 2014-04-08 Neupharma, Inc. Certain chemical entities, compositions, and methods
EP3364956A4 (fr) 2015-10-23 2019-05-01 ERX Pharmaceuticals, Inc. Analogues de célastrol
EP3480207A4 (fr) 2016-07-04 2020-03-11 Xiamen University Ligand de récepteur nucléaire orphelin nur77 et son application
US10683292B2 (en) 2016-07-25 2020-06-16 Nerviano Medical Sciences S.R.L. Purine and 3-deazapurine analogues as choline kinase inhibitors
JP7178401B2 (ja) 2017-07-11 2022-11-25 ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ コリンキナーゼ阻害剤としてのピラゾロキナゾリン誘導体
WO2020257658A1 (fr) 2019-06-20 2020-12-24 University Of Iowa Research Foundation Nanoparticules comprenant des quinone-méthides et compositions à utiliser
CN113827599A (zh) * 2021-09-23 2021-12-24 天津国际生物医药联合研究院 去甲泽拉木醛在抗登革病毒感染中的潜在应用
CN116023426A (zh) * 2022-12-30 2023-04-28 上海海洋大学 去甲泽拉木醛衍生物及其在制备抗癌药物中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328309A (en) * 1980-07-02 1982-05-04 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Method for producing tripdiolide, triptolide and celastrol
DE4117854A1 (de) * 1991-05-31 1992-12-03 Wiemann Wolfram Verwendung mindestens eines celastroloids als bestandteil fuer ein arzneimittel zur behandlung von erkrankungen des rheumatoiden formenkreises, insbesondere rheumatismus
US5650167A (en) * 1995-11-16 1997-07-22 Dawa Incorporated Method and composition for treating hepatitis B
ES2117950B1 (es) 1996-08-02 1999-09-16 Univ Granada Nuevos compuestos que bloquean la biosintesis de fosforilcolina y su uso como segundo mensajero en proliferacion celular.
CN1155610C (zh) * 2002-11-05 2004-06-30 浙江大学 具有抗氧化和抗肿瘤活性扁蒴藤素系列衍生物及合成方法
US20040220267A1 (en) * 2003-02-07 2004-11-04 Devlin J. P. Derivatives of pentacyclic nortriterpene quinone methides as compounds useful in the treatment of inflammatory, neurodegenerative, and neoplastic diseases

Also Published As

Publication number Publication date
ES2277568B1 (es) 2008-04-01
BRPI0620845A2 (pt) 2011-11-22
JP2009522239A (ja) 2009-06-11
RU2008131311A (ru) 2010-02-10
AU2006334359A1 (en) 2007-07-12
EP1976533A2 (fr) 2008-10-08
AU2006334359A2 (en) 2008-08-07
CN101351211A (zh) 2009-01-21
CA2635318A1 (fr) 2007-07-12
ES2277568A1 (es) 2007-07-01
KR20080083044A (ko) 2008-09-12
WO2007077203A3 (fr) 2007-08-30
WO2007077203A2 (fr) 2007-07-12

Similar Documents

Publication Publication Date Title
MX2008008556A (es) Derivados de triterpenoquinonas y triterpenofenoles y su aplicacion para el tratamiento de tumores y enfermedades parasitarias.
IL260127B (en) mek inhibitors and methods of using them
WO2005013892A3 (fr) Agents therapeutiques contenant du bore et a resistance hydrolytique et procedes pour les utiliser
IL184898A0 (en) Pyrrolopyrimidine derivatives and pharmaceutical compositions containing the same
TW200745078A (en) Isoindole-imide compounds and compositions comprising and methods of using the same
UA94901C2 (ru) Антибактериальные производные пиперидина
ATE456565T1 (de) Pyridin- und pyrazinderivate als mnk- kinaseinhibitoren
DK2324008T3 (da) Diarylpyrazol som protein kinase inhibitorer
MX2008012422A (es) Derivados de furano y tiofeno, pirrol substituido con pirimidinil y piridil como inhibidores de cinasa.
IL196543A (en) Pyridazinone derivatives, pharmaceutical preparations containing them for use in the treatment of disorders
UA92000C2 (en) 1-benzylindole-2-carboxamide derivatives
MX2007013624A (es) Inhibidores de proteina cinasa.
TW200833693A (en) Substituted pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors
MY143795A (en) Tetrahydropyridoindole derivatives
TW200736229A (en) Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
NO20081844L (no) Terapeutiske forbindelser
TW200716204A (en) Pharmaceutical composition
MX2007007027A (es) Derivados piperazinilpiridina como agentes anti-obesidad.
IL179206A0 (en) Pyrrolylpyrimidine derivatives and pharmaceutical compositions containing the same
BRPI0413438A (pt) derivados de pirimidilpirrol ativos como inibidores de cinase
TW200732304A (en) Piperidine derivatives
WO2009015369A3 (fr) Composés qui inhibent l'activité de la bêta-sécrétase et procédés d'utilisation de ceux-ci
BR112019007591A2 (pt) inibidores de bromodomínios
WO2005080549A3 (fr) Trioxacarcine et son utilisation
TW200603791A (en) Compounds and compositions as cathepsin S inhibitors