MX2007014954A - Derivados de 2-(1h-indolilsulfanil)-aril-amina. - Google Patents
Derivados de 2-(1h-indolilsulfanil)-aril-amina.Info
- Publication number
- MX2007014954A MX2007014954A MX2007014954A MX2007014954A MX2007014954A MX 2007014954 A MX2007014954 A MX 2007014954A MX 2007014954 A MX2007014954 A MX 2007014954A MX 2007014954 A MX2007014954 A MX 2007014954A MX 2007014954 A MX2007014954 A MX 2007014954A
- Authority
- MX
- Mexico
- Prior art keywords
- phenyl
- ylsulfanyl
- indol
- methylamine
- ethyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims abstract description 167
- -1 compounds Compound Chemical class 0.000 claims description 88
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 claims description 54
- 239000001257 hydrogen Substances 0.000 claims description 40
- 229910052739 hydrogen Inorganic materials 0.000 claims description 40
- 150000003839 salts Chemical class 0.000 claims description 40
- 238000011282 treatment Methods 0.000 claims description 37
- 125000000217 alkyl group Chemical group 0.000 claims description 31
- 229910052736 halogen Inorganic materials 0.000 claims description 31
- 150000002367 halogens Chemical group 0.000 claims description 31
- 239000008194 pharmaceutical composition Substances 0.000 claims description 31
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 30
- 239000012458 free base Substances 0.000 claims description 26
- 150000002431 hydrogen Chemical class 0.000 claims description 25
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 23
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 claims description 21
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 claims description 19
- 229960002748 norepinephrine Drugs 0.000 claims description 19
- 201000010099 disease Diseases 0.000 claims description 16
- 230000005764 inhibitory process Effects 0.000 claims description 16
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 claims description 15
- 229910052757 nitrogen Inorganic materials 0.000 claims description 15
- 208000020401 Depressive disease Diseases 0.000 claims description 14
- 208000035475 disorder Diseases 0.000 claims description 14
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims description 14
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 14
- 229940076279 serotonin Drugs 0.000 claims description 13
- 125000005842 heteroatom Chemical group 0.000 claims description 11
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 11
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- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims description 10
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 claims description 9
- 239000003085 diluting agent Substances 0.000 claims description 9
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 9
- 229910052760 oxygen Inorganic materials 0.000 claims description 9
- 239000001301 oxygen Substances 0.000 claims description 9
- 229910052717 sulfur Chemical group 0.000 claims description 9
- 208000027520 Somatoform disease Diseases 0.000 claims description 8
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 8
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 8
- 230000000694 effects Effects 0.000 claims description 8
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- 108010012996 Serotonin Plasma Membrane Transport Proteins Proteins 0.000 claims description 7
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- 229940127221 norepinephrine reuptake inhibitor Drugs 0.000 claims description 5
- 208000017194 Affective disease Diseases 0.000 claims description 4
- 102000006441 Dopamine Plasma Membrane Transport Proteins Human genes 0.000 claims description 4
- 108010044266 Dopamine Plasma Membrane Transport Proteins Proteins 0.000 claims description 4
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- 102000008092 Norepinephrine Plasma Membrane Transport Proteins Human genes 0.000 claims description 4
- 108010049586 Norepinephrine Plasma Membrane Transport Proteins Proteins 0.000 claims description 4
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 4
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- DQPAGLBQGKUVKT-UHFFFAOYSA-N 2-[2-(1h-indol-3-ylsulfanyl)-4,5-dimethoxyphenyl]-n-methylethanamine Chemical compound CNCCC1=CC(OC)=C(OC)C=C1SC1=CNC2=CC=CC=C12 DQPAGLBQGKUVKT-UHFFFAOYSA-N 0.000 claims description 3
- RIMCVADQHDOBGR-UHFFFAOYSA-N 2-[2-[(4-chloro-1h-indol-3-yl)sulfanyl]phenyl]-n-methylethanamine Chemical compound CNCCC1=CC=CC=C1SC1=CNC2=CC=CC(Cl)=C12 RIMCVADQHDOBGR-UHFFFAOYSA-N 0.000 claims description 3
- QJQJODCAYMBBOA-UHFFFAOYSA-N 2-[2-[(6-fluoro-1h-indol-3-yl)sulfanyl]phenyl]-n-methylethanamine Chemical compound CNCCC1=CC=CC=C1SC1=CNC2=CC(F)=CC=C12 QJQJODCAYMBBOA-UHFFFAOYSA-N 0.000 claims description 3
- RNBZMVSYRDYWPZ-UHFFFAOYSA-N 2-[2-[(7-fluoro-1h-indol-3-yl)sulfanyl]phenyl]-n-methylethanamine Chemical compound CNCCC1=CC=CC=C1SC1=CNC2=C(F)C=CC=C12 RNBZMVSYRDYWPZ-UHFFFAOYSA-N 0.000 claims description 3
- YOOGDLBGZBCOOL-UHFFFAOYSA-N 2-[2-[(7-methoxy-1h-indol-3-yl)sulfanyl]phenyl]-n-methylethanamine Chemical compound CNCCC1=CC=CC=C1SC1=CNC2=C(OC)C=CC=C12 YOOGDLBGZBCOOL-UHFFFAOYSA-N 0.000 claims description 3
- LNKSUCWXHZGBGF-UHFFFAOYSA-N 2-[5-fluoro-2-(1h-indol-3-ylsulfanyl)phenyl]-n-methylethanamine Chemical compound CNCCC1=CC(F)=CC=C1SC1=CNC2=CC=CC=C12 LNKSUCWXHZGBGF-UHFFFAOYSA-N 0.000 claims description 3
- MFAKBZPNIWVEKG-UHFFFAOYSA-N 3-[2-(1h-indol-3-ylsulfanyl)phenyl]-n-methylpropan-1-amine Chemical compound CNCCCC1=CC=CC=C1SC1=CNC2=CC=CC=C12 MFAKBZPNIWVEKG-UHFFFAOYSA-N 0.000 claims description 3
- BJYPYNKXPNCMAG-UHFFFAOYSA-N 4-[2-[2-(1h-indol-3-ylsulfanyl)phenyl]ethyl]morpholine Chemical compound C=1C=CC=C(SC=2C3=CC=CC=C3NC=2)C=1CCN1CCOCC1 BJYPYNKXPNCMAG-UHFFFAOYSA-N 0.000 claims description 3
- QLXNOQBWMYRPJE-UHFFFAOYSA-N 4-[2-[2-(1h-indol-3-ylsulfanyl)phenyl]ethyl]thiomorpholine Chemical compound C=1C=CC=C(SC=2C3=CC=CC=C3NC=2)C=1CCN1CCSCC1 QLXNOQBWMYRPJE-UHFFFAOYSA-N 0.000 claims description 3
- 101100495914 Arabidopsis thaliana ETL1 gene Proteins 0.000 claims description 3
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- 229940121991 Serotonin and norepinephrine reuptake inhibitor Drugs 0.000 claims description 3
- 208000007613 Shoulder Pain Diseases 0.000 claims description 3
- 231100000869 headache Toxicity 0.000 claims description 3
- ICPDRZWPWMKFRH-UHFFFAOYSA-N 2-[2-(1h-indol-3-ylsulfanyl)phenyl]-n,n-dimethylethanamine Chemical compound CN(C)CCC1=CC=CC=C1SC1=CNC2=CC=CC=C12 ICPDRZWPWMKFRH-UHFFFAOYSA-N 0.000 claims description 2
- WLCRVWHOFBNTLR-UHFFFAOYSA-N 2-[2-(1h-indol-3-ylsulfanyl)phenyl]-n-methylethanamine Chemical compound CNCCC1=CC=CC=C1SC1=CNC2=CC=CC=C12 WLCRVWHOFBNTLR-UHFFFAOYSA-N 0.000 claims description 2
- YJWYWKYCWYOLHL-UHFFFAOYSA-N 2-[2-[(4-fluoro-1h-indol-3-yl)sulfanyl]phenyl]-n-methylethanamine Chemical compound CNCCC1=CC=CC=C1SC1=CNC2=CC=CC(F)=C12 YJWYWKYCWYOLHL-UHFFFAOYSA-N 0.000 claims description 2
- FFQRPQADRFJXBR-UHFFFAOYSA-N 2-[2-[(5-fluoro-1h-indol-3-yl)sulfanyl]phenyl]-n-methylethanamine Chemical compound CNCCC1=CC=CC=C1SC1=CNC2=CC=C(F)C=C12 FFQRPQADRFJXBR-UHFFFAOYSA-N 0.000 claims description 2
- DMVJPZPTGURZBL-UHFFFAOYSA-N 2-[2-[(6-fluoro-1h-indol-3-yl)sulfanyl]-4,5-dimethoxyphenyl]-n-methylethanamine Chemical compound CNCCC1=CC(OC)=C(OC)C=C1SC1=CNC2=CC(F)=CC=C12 DMVJPZPTGURZBL-UHFFFAOYSA-N 0.000 claims description 2
- JZOKUXUBUSALFY-UHFFFAOYSA-N 2-[5-chloro-2-(1h-indol-3-ylsulfanyl)phenyl]-n-methylethanamine Chemical compound CNCCC1=CC(Cl)=CC=C1SC1=CNC2=CC=CC=C12 JZOKUXUBUSALFY-UHFFFAOYSA-N 0.000 claims description 2
- SRDPGAAMUNUOIS-UHFFFAOYSA-N 3-[2-[(4-chloro-1h-indol-3-yl)sulfanyl]phenyl]-n-methylpropan-1-amine Chemical compound CNCCCC1=CC=CC=C1SC1=CNC2=CC=CC(Cl)=C12 SRDPGAAMUNUOIS-UHFFFAOYSA-N 0.000 claims description 2
- DYUYSUSCPXONTN-UHFFFAOYSA-N 3-[2-[(6-fluoro-1h-indol-3-yl)sulfanyl]phenyl]-n-methylpropan-1-amine Chemical compound CNCCCC1=CC=CC=C1SC1=CNC2=CC(F)=CC=C12 DYUYSUSCPXONTN-UHFFFAOYSA-N 0.000 claims description 2
- BTRYKXYPTODPPY-UHFFFAOYSA-N 4-[2-(1h-indol-3-ylsulfanyl)phenyl]-n-methylbutan-1-amine Chemical compound CNCCCCC1=CC=CC=C1SC1=CNC2=CC=CC=C12 BTRYKXYPTODPPY-UHFFFAOYSA-N 0.000 claims description 2
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- SAHZVUTZRRRCOC-UHFFFAOYSA-N n-methyl-4-[2-(1-methylindol-3-yl)sulfanylphenyl]butan-1-amine Chemical compound CNCCCCC1=CC=CC=C1SC1=CN(C)C2=CC=CC=C12 SAHZVUTZRRRCOC-UHFFFAOYSA-N 0.000 claims description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 2
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- MVBGNZJNMIRAMA-UHFFFAOYSA-N 3-[2-[(4-methoxy-1h-indol-3-yl)sulfanyl]phenyl]-n-methylpropan-1-amine Chemical compound CNCCCC1=CC=CC=C1SC1=CNC2=CC=CC(OC)=C12 MVBGNZJNMIRAMA-UHFFFAOYSA-N 0.000 claims 1
- ZHDDBWQTGUSZCV-UHFFFAOYSA-N 4-[2-[(4-methoxy-1h-indol-3-yl)sulfanyl]phenyl]-n-methylbutan-1-amine Chemical compound CNCCCCC1=CC=CC=C1SC1=CNC2=CC=CC(OC)=C12 ZHDDBWQTGUSZCV-UHFFFAOYSA-N 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- CEFGTUXAYJORMD-UHFFFAOYSA-N n-methyl-3-[2-(1-methylindol-3-yl)sulfanylphenyl]propan-1-amine Chemical compound CNCCCC1=CC=CC=C1SC1=CN(C)C2=CC=CC=C12 CEFGTUXAYJORMD-UHFFFAOYSA-N 0.000 claims 1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69200905P | 2005-06-17 | 2005-06-17 | |
| PCT/IB2006/002785 WO2006134499A2 (en) | 2005-06-17 | 2006-06-14 | 2-(1h-indolylsulfanyl)-aryl amine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007014954A true MX2007014954A (es) | 2008-02-15 |
Family
ID=37532681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007014954A MX2007014954A (es) | 2005-06-17 | 2006-06-14 | Derivados de 2-(1h-indolilsulfanil)-aril-amina. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1893575B1 (enExample) |
| JP (1) | JP5144507B2 (enExample) |
| KR (1) | KR20080027462A (enExample) |
| CN (1) | CN101238101A (enExample) |
| AR (1) | AR054394A1 (enExample) |
| AU (1) | AU2006257288A1 (enExample) |
| BR (1) | BRPI0611748A2 (enExample) |
| CA (1) | CA2611566C (enExample) |
| EA (1) | EA200800070A1 (enExample) |
| ES (1) | ES2616095T3 (enExample) |
| IL (1) | IL188064A0 (enExample) |
| MX (1) | MX2007014954A (enExample) |
| NO (1) | NO20080265L (enExample) |
| WO (1) | WO2006134499A2 (enExample) |
| ZA (1) | ZA200710885B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100286226A1 (en) * | 2007-09-24 | 2010-11-11 | H. Lundbeck A/S | Combination therapy related to serotonin dual action compounds |
| TW200938189A (en) * | 2008-03-13 | 2009-09-16 | Lundbeck & Co As H | [2-(6-flouro-1H-indol-3-ylsulfanyl)benzyl]methyl amine for the treatment of affective disorders |
| US9000025B2 (en) | 2010-08-20 | 2015-04-07 | Amira Pharmaceuticals, Inc. | Autotaxin inhibitors and uses thereof |
| WO2012166415A1 (en) | 2011-05-27 | 2012-12-06 | Amira Pharmaceuticals, Inc. | Heterocyclic autotaxin inhibitors and uses thereof |
| CA2900604A1 (en) * | 2013-03-15 | 2014-09-25 | Chromocell Corporation | Sodium channel modulators for the treatment of pain |
| WO2015042053A1 (en) | 2013-09-17 | 2015-03-26 | Pharmakea, Inc. | Vinyl autotaxin inhibitor compounds |
| US9951026B2 (en) | 2013-09-17 | 2018-04-24 | Pharmakea, Inc. | Heterocyclic vinyl autotaxin inhibitor compounds |
| EP3049405A4 (en) | 2013-09-26 | 2017-03-08 | Pharmakea Inc. | Autotaxin inhibitor compounds |
| HRP20210957T1 (hr) | 2013-11-22 | 2021-09-17 | Sabre Therapeutics Llc | Spojevi inhibitori autotaksina |
| EP4026549A1 (en) | 2015-05-27 | 2022-07-13 | Sabre Therapeutics LLC | Autotaxin inhibitors and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4117129A (en) * | 1976-10-22 | 1978-09-26 | Warner-Lambert Company | Indolobenzoxazepines as cns depressants |
| ATE195125T1 (de) * | 1995-11-06 | 2000-08-15 | Dsm Nv | Verfahren zur de-esterifikation |
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| TW200400177A (en) * | 2002-06-04 | 2004-01-01 | Wyeth Corp | 1-(Aminoalkyl)-3-sulfonylindole and-indazole derivatives as 5-hydroxytryptamine-6 ligands |
| ATE396970T1 (de) * | 2003-12-23 | 2008-06-15 | Lundbeck & Co As H | 2-(1h-indolylsulfanyl)-benzylaminderivate als ssri |
| AR052308A1 (es) * | 2004-07-16 | 2007-03-14 | Lundbeck & Co As H | Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto |
-
2006
- 2006-06-13 AR ARP060102491A patent/AR054394A1/es not_active Application Discontinuation
- 2006-06-14 WO PCT/IB2006/002785 patent/WO2006134499A2/en not_active Ceased
- 2006-06-14 MX MX2007014954A patent/MX2007014954A/es not_active Application Discontinuation
- 2006-06-14 KR KR1020077029334A patent/KR20080027462A/ko not_active Withdrawn
- 2006-06-14 EA EA200800070A patent/EA200800070A1/ru unknown
- 2006-06-14 JP JP2008516452A patent/JP5144507B2/ja not_active Expired - Fee Related
- 2006-06-14 ZA ZA200710885A patent/ZA200710885B/xx unknown
- 2006-06-14 CN CNA2006800218382A patent/CN101238101A/zh active Pending
- 2006-06-14 EP EP06808965.5A patent/EP1893575B1/en active Active
- 2006-06-14 CA CA2611566A patent/CA2611566C/en not_active Expired - Fee Related
- 2006-06-14 AU AU2006257288A patent/AU2006257288A1/en not_active Abandoned
- 2006-06-14 BR BRPI0611748A patent/BRPI0611748A2/pt not_active IP Right Cessation
- 2006-06-14 ES ES06808965.5T patent/ES2616095T3/es active Active
-
2007
- 2007-12-11 IL IL188064A patent/IL188064A0/en unknown
-
2008
- 2008-01-15 NO NO20080265A patent/NO20080265L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006134499A3 (en) | 2007-04-12 |
| CA2611566C (en) | 2011-08-16 |
| CN101238101A (zh) | 2008-08-06 |
| EP1893575B1 (en) | 2017-01-11 |
| CA2611566A1 (en) | 2006-12-21 |
| AU2006257288A1 (en) | 2006-12-21 |
| BRPI0611748A2 (pt) | 2016-11-22 |
| AR054394A1 (es) | 2007-06-20 |
| KR20080027462A (ko) | 2008-03-27 |
| JP2008546679A (ja) | 2008-12-25 |
| ES2616095T3 (es) | 2017-06-09 |
| IL188064A0 (en) | 2008-03-20 |
| ZA200710885B (en) | 2009-03-25 |
| JP5144507B2 (ja) | 2013-02-13 |
| EP1893575A2 (en) | 2008-03-05 |
| EA200800070A1 (ru) | 2008-04-28 |
| WO2006134499A2 (en) | 2006-12-21 |
| NO20080265L (no) | 2008-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |