MX2007012394A - Procesos para la preparacion de farmacos anticancer. - Google Patents

Procesos para la preparacion de farmacos anticancer.

Info

Publication number
MX2007012394A
MX2007012394A MX2007012394A MX2007012394A MX2007012394A MX 2007012394 A MX2007012394 A MX 2007012394A MX 2007012394 A MX2007012394 A MX 2007012394A MX 2007012394 A MX2007012394 A MX 2007012394A MX 2007012394 A MX2007012394 A MX 2007012394A
Authority
MX
Mexico
Prior art keywords
process according
toluene
solvent
temperature
group
Prior art date
Application number
MX2007012394A
Other languages
English (en)
Spanish (es)
Inventor
Marco Villa
Roberta Fretta
Nicola Diulgheroff
Alessandro Pontiroli
Original Assignee
Sicor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sicor Inc filed Critical Sicor Inc
Publication of MX2007012394A publication Critical patent/MX2007012394A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
MX2007012394A 2005-04-06 2006-04-06 Procesos para la preparacion de farmacos anticancer. MX2007012394A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66913205P 2005-04-06 2005-04-06
US69452805P 2005-06-27 2005-06-27
PCT/US2006/013140 WO2006108155A2 (en) 2005-04-06 2006-04-06 Process for the preparation of anastrozole

Publications (1)

Publication Number Publication Date
MX2007012394A true MX2007012394A (es) 2007-11-07

Family

ID=36694325

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007012394A MX2007012394A (es) 2005-04-06 2006-04-06 Procesos para la preparacion de farmacos anticancer.

Country Status (8)

Country Link
US (2) US7692025B2 (enExample)
EP (2) EP1751121A2 (enExample)
JP (1) JP2008536836A (enExample)
KR (1) KR20080000621A (enExample)
CA (1) CA2601649A1 (enExample)
IL (1) IL184944A0 (enExample)
MX (1) MX2007012394A (enExample)
WO (1) WO2006108155A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2601649A1 (en) 2005-04-06 2006-10-12 Sicor Inc. Process for the preparation of anastrozole
AR061016A1 (es) * 2006-05-19 2008-07-30 Synthon Bv Proceso para la purificacion de anastrozol
US8058302B2 (en) * 2006-06-05 2011-11-15 Cadila Healthcare Limited Process for preparing pure anastrozole
US7989636B2 (en) * 2006-10-17 2011-08-02 Cipla Limited Process for the preparation of pure anastrozole
WO2009010991A2 (en) * 2007-07-17 2009-01-22 Ind-Swift Laboratories Limited Purification process to prepare highly pure anastrozole
EP2343278A1 (en) 2010-01-07 2011-07-13 Hexal AG A process for preparing trisubstituted phenyl derivatives comprising a (1H-1,2,4-triazol-1-yl)alkyl group
CN106083748B (zh) * 2016-06-21 2019-08-16 扬子江药业集团江苏海慈生物药业有限公司 一种阿那曲唑的制备方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714013D0 (en) * 1987-06-16 1987-07-22 Ici Plc (substituted-aralkyl)heterocyclic compounds
JPH07138234A (ja) * 1993-11-11 1995-05-30 Kureha Chem Ind Co Ltd アゾリルメチルシクロアルカノール誘導体の製造方法
EP1165512A2 (de) * 1999-03-30 2002-01-02 Gödecke Gmbh Verfahren zur herstellung von n-aryl-aza-heterocyclen in gegenwart von cesiumcarbonat
US8436029B2 (en) 2004-03-19 2013-05-07 Transform Pharmaceuticals, Inc. Pharmaceutical forms, and methods of making and using the same
WO2005105762A1 (en) * 2004-05-05 2005-11-10 Natco Pharma Limited Improved process for the preparation of high purity anastrozole
GB0412492D0 (en) 2004-06-04 2004-07-07 Sterix Ltd Compound
DE102005037484A1 (de) * 2004-08-09 2006-02-23 Chemagis Ltd. Neue Verfahren zur Herstellung von im Wesentlichen reinem Anastrozol
US20060189670A1 (en) 2005-02-22 2006-08-24 Glenmark Pharmaceuticals Limited Process for the preparation of anastrozole and intermediates thereof
EP1705168A1 (en) * 2005-03-21 2006-09-27 Helm AG Improved process for side-chain bromination of alkyl-benzenes
CA2601649A1 (en) * 2005-04-06 2006-10-12 Sicor Inc. Process for the preparation of anastrozole
WO2007002722A2 (en) 2005-06-27 2007-01-04 Sicor, Inc. Synthesis of anastrozole and purification of one of its intermediate
US20090221837A1 (en) 2005-09-30 2009-09-03 Kirtipalsinh Saijansinh Solanki Process for the Preparation of Pure Anastrozole
WO2007039913A1 (en) * 2005-10-05 2007-04-12 Usv Limited Process for the preparation of 2,2’-[5-(1,2,4-triazole-1-ylmethyl) -1,3-phenylene] di (2-methylpropionitrile).
WO2007039919A1 (en) 2005-10-06 2007-04-12 Natco Pharma Limited Crystalline forms of anastrozole
US20070100148A1 (en) 2005-10-31 2007-05-03 Veerender Murki Process for preparing anastrozole
WO2007105231A1 (en) 2006-03-10 2007-09-20 Shilpa Medicare Ltd. Improved process for high purity anastrozole
AR061016A1 (es) * 2006-05-19 2008-07-30 Synthon Bv Proceso para la purificacion de anastrozol
US8058302B2 (en) 2006-06-05 2011-11-15 Cadila Healthcare Limited Process for preparing pure anastrozole
FR2904821B1 (fr) 2006-08-09 2009-02-20 Air Liquide Procede de purification d'hydrogene
WO2008034644A2 (en) 2006-09-22 2008-03-27 Synthon B.V. Process for making anastrozole
US7989636B2 (en) 2006-10-17 2011-08-02 Cipla Limited Process for the preparation of pure anastrozole
US20080177081A1 (en) * 2007-01-19 2008-07-24 Formosa Laboratories, Inc. Process for Preparation of Anastrozole

Also Published As

Publication number Publication date
US7692025B2 (en) 2010-04-06
CA2601649A1 (en) 2006-10-12
WO2006108155A2 (en) 2006-10-12
EP2172449A3 (en) 2011-06-22
KR20080000621A (ko) 2008-01-02
EP1751121A2 (en) 2007-02-14
JP2008536836A (ja) 2008-09-11
WO2006108155A3 (en) 2006-11-23
US20060276657A1 (en) 2006-12-07
EP2172449A2 (en) 2010-04-07
US20100099888A1 (en) 2010-04-22
IL184944A0 (en) 2007-12-03

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