MX2007006690A - Analogos 12-aril de prostaglandina. - Google Patents

Analogos 12-aril de prostaglandina.

Info

Publication number
MX2007006690A
MX2007006690A MX2007006690A MX2007006690A MX2007006690A MX 2007006690 A MX2007006690 A MX 2007006690A MX 2007006690 A MX2007006690 A MX 2007006690A MX 2007006690 A MX2007006690 A MX 2007006690A MX 2007006690 A MX2007006690 A MX 2007006690A
Authority
MX
Mexico
Prior art keywords
prostaglandin analogs
disclosed
aryl
aryl prostaglandin
prostaglandin
Prior art date
Application number
MX2007006690A
Other languages
English (en)
Inventor
Yariv Donde
Jeremiah H Nguyen
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of MX2007006690A publication Critical patent/MX2007006690A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

Se describen compuestos que comprenden la formula (I), (ver formula (I)) en donde Y, A, X, R, D y n son como se describe. Un compuesto que comprende un agonista selectivo de prostaglandina EP2 en donde la cadena ( comprende un fenilo substituido, en donde al menos un substituyente consiste de hidrocarbilo o hidroxihidrocarbilo no lineal tambien se describe en la presente. Los metodos, composiciones y medicamentos relacionados de los mismos tambien se describen.
MX2007006690A 2004-12-10 2005-12-08 Analogos 12-aril de prostaglandina. MX2007006690A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/009,298 US7091231B2 (en) 2004-12-10 2004-12-10 12-Aryl prostaglandin analogs
PCT/US2005/044501 WO2006063179A1 (en) 2004-12-10 2005-12-08 12-aryl prostaglandin analogs

Publications (1)

Publication Number Publication Date
MX2007006690A true MX2007006690A (es) 2007-08-14

Family

ID=36578246

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007006690A MX2007006690A (es) 2004-12-10 2005-12-08 Analogos 12-aril de prostaglandina.

Country Status (21)

Country Link
US (3) US7091231B2 (es)
EP (1) EP1819670B1 (es)
JP (1) JP5342142B2 (es)
KR (1) KR101367553B1 (es)
CN (1) CN101107225B (es)
AR (1) AR052264A1 (es)
AU (1) AU2005314000B2 (es)
BR (1) BRPI0518642A2 (es)
CA (1) CA2589864C (es)
DK (1) DK1819670T3 (es)
ES (1) ES2394838T3 (es)
HK (1) HK1114832A1 (es)
IL (1) IL183360A (es)
MX (1) MX2007006690A (es)
NO (1) NO20072662L (es)
NZ (1) NZ555352A (es)
PL (1) PL216197B1 (es)
RU (1) RU2439055C2 (es)
TW (1) TWI392666B (es)
WO (1) WO2006063179A1 (es)
ZA (1) ZA200704087B (es)

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Also Published As

Publication number Publication date
JP2008523088A (ja) 2008-07-03
JP5342142B2 (ja) 2013-11-13
CN101107225B (zh) 2012-11-28
RU2007120520A (ru) 2009-01-20
TWI392666B (zh) 2013-04-11
HK1114832A1 (en) 2008-11-14
AU2005314000B2 (en) 2012-06-14
DK1819670T3 (da) 2012-09-17
IL183360A (en) 2010-12-30
US20060148894A1 (en) 2006-07-06
NO20072662L (no) 2007-09-04
IL183360A0 (en) 2007-09-20
EP1819670B1 (en) 2012-08-08
CN101107225A (zh) 2008-01-16
AU2005314000A1 (en) 2006-06-15
AR052264A1 (es) 2007-03-07
US8044092B2 (en) 2011-10-25
CA2589864A1 (en) 2006-06-15
ES2394838T3 (es) 2013-02-06
EP1819670A1 (en) 2007-08-22
TW200633966A (en) 2006-10-01
RU2439055C2 (ru) 2012-01-10
ZA200704087B (en) 2008-09-25
US7799821B2 (en) 2010-09-21
US7091231B2 (en) 2006-08-15
KR101367553B1 (ko) 2014-03-14
KR20070086001A (ko) 2007-08-27
PL383422A1 (pl) 2008-03-17
US20060205800A1 (en) 2006-09-14
BRPI0518642A2 (pt) 2008-12-02
PL216197B1 (pl) 2014-03-31
US20100317872A1 (en) 2010-12-16
CA2589864C (en) 2015-02-03
WO2006063179A1 (en) 2006-06-15
NZ555352A (en) 2011-01-28

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