MX2007004660A - Uso de 4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-(piridin-3- il)pirimidin-2-ilamino)fenil]-benzamida para inhibir el receptor de tirosina cinasa c-fms. - Google Patents
Uso de 4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-(piridin-3- il)pirimidin-2-ilamino)fenil]-benzamida para inhibir el receptor de tirosina cinasa c-fms.Info
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- MX2007004660A MX2007004660A MX2007004660A MX2007004660A MX2007004660A MX 2007004660 A MX2007004660 A MX 2007004660A MX 2007004660 A MX2007004660 A MX 2007004660A MX 2007004660 A MX2007004660 A MX 2007004660A MX 2007004660 A MX2007004660 A MX 2007004660A
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- Prior art keywords
- fms
- compound
- csf
- microglial
- methyl
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61974404P | 2004-10-18 | 2004-10-18 | |
| PCT/AU2005/001602 WO2006042362A1 (en) | 2004-10-18 | 2005-10-17 | Use of 4-(4-methylpiperazin-1-ylmethyl)-n-[4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl]-benzamide to inhibit the tyrosine kinase receptor c-fms |
Publications (1)
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|---|---|
| MX2007004660A true MX2007004660A (es) | 2007-10-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007004660A MX2007004660A (es) | 2004-10-18 | 2005-10-17 | Uso de 4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-(piridin-3- il)pirimidin-2-ilamino)fenil]-benzamida para inhibir el receptor de tirosina cinasa c-fms. |
Country Status (19)
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| EP (1) | EP1804800B1 (https=) |
| JP (1) | JP2008516898A (https=) |
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| AT (1) | ATE492277T1 (https=) |
| AU (1) | AU2005297321A1 (https=) |
| BR (1) | BRPI0517083A (https=) |
| CA (1) | CA2580976A1 (https=) |
| DE (1) | DE602005025514D1 (https=) |
| IL (1) | IL182419A0 (https=) |
| MA (1) | MA28946B1 (https=) |
| MX (1) | MX2007004660A (https=) |
| NO (1) | NO20072501L (https=) |
| NZ (1) | NZ554009A (https=) |
| RU (1) | RU2007118420A (https=) |
| TN (1) | TNSN07141A1 (https=) |
| WO (1) | WO2006042362A1 (https=) |
| ZA (1) | ZA200702316B (https=) |
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| WO2009058968A2 (en) * | 2007-10-31 | 2009-05-07 | Janssen Pharmaceutica N.V. | Biomarker for assessing response to fms treatment |
| CN107530430A (zh) * | 2015-01-13 | 2018-01-02 | 国立大学法人京都大学 | 用于预防和/或治疗肌萎缩性侧索硬化症的药剂 |
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| US4837237A (en) * | 1985-07-09 | 1989-06-06 | Fred Hutchinson Cancer Research Center | Therapy using glucosidase processing inhibitors |
| DE60212836T2 (de) * | 2001-05-16 | 2007-01-25 | Gpc Biotech Ag | Pyridylpyrimidin-derivate als wirksame verbindungen gegen prionen-krankheiten |
| WO2004026930A2 (en) * | 2002-06-26 | 2004-04-01 | The Ohio State University Research Foundation | The method for reducing inflammation using sti-571 or its salt |
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2005
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- 2005-10-17 JP JP2007535954A patent/JP2008516898A/ja active Pending
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- 2005-10-17 WO PCT/AU2005/001602 patent/WO2006042362A1/en not_active Ceased
- 2005-10-17 BR BRPI0517083-4A patent/BRPI0517083A/pt not_active IP Right Cessation
- 2005-10-17 US US11/576,967 patent/US20080255139A1/en not_active Abandoned
- 2005-10-17 NZ NZ554009A patent/NZ554009A/en not_active IP Right Cessation
- 2005-10-17 EP EP05793868A patent/EP1804800B1/en not_active Expired - Lifetime
- 2005-10-17 AT AT05793868T patent/ATE492277T1/de not_active IP Right Cessation
- 2005-10-17 AU AU2005297321A patent/AU2005297321A1/en not_active Abandoned
- 2005-10-17 MX MX2007004660A patent/MX2007004660A/es unknown
- 2005-10-17 KR KR1020077008716A patent/KR20070083705A/ko not_active Ceased
- 2005-10-17 DE DE602005025514T patent/DE602005025514D1/de not_active Expired - Lifetime
- 2005-10-17 RU RU2007118420/15A patent/RU2007118420A/ru unknown
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2007
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- 2007-04-10 IL IL182419A patent/IL182419A0/en unknown
- 2007-04-17 TN TNP2007000141A patent/TNSN07141A1/fr unknown
- 2007-04-25 MA MA29848A patent/MA28946B1/fr unknown
- 2007-05-15 NO NO20072501A patent/NO20072501L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005297321A1 (en) | 2006-04-27 |
| MA28946B1 (fr) | 2007-10-01 |
| DE602005025514D1 (de) | 2011-02-03 |
| NO20072501L (no) | 2007-05-15 |
| KR20070083705A (ko) | 2007-08-24 |
| NZ554009A (en) | 2010-09-30 |
| JP2008516898A (ja) | 2008-05-22 |
| IL182419A0 (en) | 2007-09-20 |
| TNSN07141A1 (en) | 2008-11-21 |
| EP1804800B1 (en) | 2010-12-22 |
| ZA200702316B (en) | 2008-09-25 |
| WO2006042362A1 (en) | 2006-04-27 |
| CA2580976A1 (en) | 2006-04-27 |
| EP1804800A4 (en) | 2008-03-19 |
| BRPI0517083A (pt) | 2008-09-30 |
| ATE492277T1 (de) | 2011-01-15 |
| EP1804800A1 (en) | 2007-07-11 |
| RU2007118420A (ru) | 2008-11-27 |
| CN101035535A (zh) | 2007-09-12 |
| US20080255139A1 (en) | 2008-10-16 |
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