MX165338B - Entrega transdermica electrolitica de polipeptidos - Google Patents

Entrega transdermica electrolitica de polipeptidos

Info

Publication number
MX165338B
MX165338B MX010367A MX1036788A MX165338B MX 165338 B MX165338 B MX 165338B MX 010367 A MX010367 A MX 010367A MX 1036788 A MX1036788 A MX 1036788A MX 165338 B MX165338 B MX 165338B
Authority
MX
Mexico
Prior art keywords
polypeptide
aqueous
patient
suspension
transdermic
Prior art date
Application number
MX010367A
Other languages
English (en)
Inventor
Dan Sibalis
Sanford Rosen
Original Assignee
Drud Delivery Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drud Delivery Systems Inc filed Critical Drud Delivery Systems Inc
Publication of MX165338B publication Critical patent/MX165338B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a un parche transdérmico para entregar por lo menos una droga o medicamento directamente a la corriente sanguínea del paciente que comprende en combinación a) por lo menos un polipéptido que tiene desde aproximadamente tres hasta aproximadamente 20 unidades de péptido y b) medios electrolíticos para el transporte transdérmico del polipéptido caracterizados por una densidad de corriente desde aproximadamente 0.5 microamperios/cm cuadrado hasta aproximadamente 1 miliamperio/cm cuadrado mediante lo cual la piel del paciente ni se irrita ni se forma eritema.
MX010367A 1987-02-10 1988-02-10 Entrega transdermica electrolitica de polipeptidos MX165338B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/012,889 US4878892A (en) 1987-02-10 1987-02-10 Electrolytic transdermal delivery of polypeptides

Publications (1)

Publication Number Publication Date
MX165338B true MX165338B (es) 1992-11-05

Family

ID=21757240

Family Applications (1)

Application Number Title Priority Date Filing Date
MX010367A MX165338B (es) 1987-02-10 1988-02-10 Entrega transdermica electrolitica de polipeptidos

Country Status (9)

Country Link
US (1) US4878892A (es)
EP (1) EP0278474B1 (es)
JP (1) JPH0647016B2 (es)
KR (1) KR970004037B1 (es)
AT (1) ATE135928T1 (es)
AU (1) AU608278B2 (es)
CA (1) CA1317879C (es)
DE (1) DE3855143T2 (es)
MX (1) MX165338B (es)

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US5356632A (en) * 1991-09-12 1994-10-18 S.I. Scientific Innovations Ltd. Transdermal drug delivery device
US5215520A (en) * 1991-09-17 1993-06-01 Centre Internationale De Recherches Dermatologiques Galderma (C.I.R.D. Galderma) Method for delivering an active substance topically or percutaneously
CA2087087C (en) * 1992-01-22 2000-07-18 Burton H. Sage, Jr. Molecules for iontophoretic delivery
US5443441A (en) * 1993-03-05 1995-08-22 De Claviere; Anne Marie Apparatus and method for transdermal delivery of cosmetic compositions
US5503632A (en) * 1994-04-08 1996-04-02 Alza Corporation Electrotransport device having improved cathodic electrode assembly
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US6425892B2 (en) * 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
ATE263597T1 (de) * 1995-06-05 2004-04-15 Alza Corp Vorrichtung zur transdermalen iontophoretischen verabreichung von fentanyl und sufentanil
US6216033B1 (en) 1996-05-22 2001-04-10 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
IE960375A1 (en) * 1995-06-05 1996-12-11 Alza Corp Device for transdermal electrotransport delivery of fentanyl¹and sufentanil
US7572252B1 (en) * 1995-06-07 2009-08-11 Alza Corporation Electrotransport agent delivery method and apparatus
US5983130A (en) 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
US5779661A (en) * 1995-12-11 1998-07-14 Physion, S.R.L. Method of treating dysfunctional bladder syndromes by electromotive drug administration
US6718201B1 (en) * 1996-06-07 2004-04-06 Alza Corporation Electrotransport agent delivery method and apparatus
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
CA2309955A1 (en) * 1997-11-12 1999-05-20 Alza Corporation Method for decreasing self-association of polypeptides
KR100247558B1 (ko) 1997-11-24 2000-05-01 김충섭 사이클로덱스트린을 이용한 이온토포레시스 개선방법
US6163720A (en) * 1997-12-18 2000-12-19 Alza Corporation Layered rate controlling membranes for use in an electrotransport device
US6374136B1 (en) 1997-12-22 2002-04-16 Alza Corporation Anhydrous drug reservoir for electrolytic transdermal delivery device
US6475514B1 (en) * 1998-12-03 2002-11-05 Andrew Blitzer Athletic patch
US6275728B1 (en) 1998-12-22 2001-08-14 Alza Corporation Thin polymer film drug reservoirs
WO2002015801A1 (en) * 2000-08-24 2002-02-28 Encapsulation Systems, Inc. Substance delivery system
BR0114909A (pt) 2000-10-26 2004-02-03 Alza Corp Dispositivos de distribuição de drogas transdérmicas possuindo microprotuberâncias revestidas
US20110005507A9 (en) 2001-01-23 2011-01-13 Rick Bagwell Real-time control of exhaust flow
US6908448B2 (en) * 2001-08-24 2005-06-21 Dermisonics, Inc. Substance delivery device
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
DE10228680A1 (de) * 2002-06-27 2004-01-22 Holden Development Limited, Tortola Grundlage für transdermale Formulierungen (PTF)
EP1599141A2 (en) * 2003-02-19 2005-11-30 Second Stage Ventures, Inc. Ultrasonically enhanced saline treatment for burn damaged skin
JP2006518640A (ja) * 2003-02-19 2006-08-17 セカンド ステージ ベンチャーズ インコーポレイテッド 経皮的薬物送達方法及び装置
CA2573955C (en) 2004-07-23 2013-12-17 Halton Company Improvements for control of exhaust systems
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
KR101522747B1 (ko) * 2007-08-06 2015-05-26 알레간 인코포레이티드 데스모프레신 약물 전달을 위한 방법 및 장치
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
CA2724653A1 (en) 2008-05-21 2009-11-26 Ferring International Center S.A. Orodispersible desmopressin for increasing initial period of sleep undisturbed by nocturia
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US7883487B2 (en) 2008-06-16 2011-02-08 Shantha Totada R Transdermal local anesthetic patch with injection port
PT2442821T (pt) 2009-06-18 2017-09-29 Allergan Inc Administração segura de desmopressina
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US9731121B2 (en) 2011-03-31 2017-08-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
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Also Published As

Publication number Publication date
DE3855143T2 (de) 1996-10-31
EP0278474B1 (en) 1996-03-27
KR970004037B1 (ko) 1997-03-24
DE3855143D1 (de) 1996-05-02
EP0278474A1 (en) 1988-08-17
US4878892A (en) 1989-11-07
JPS63200775A (ja) 1988-08-19
KR880009632A (ko) 1988-10-04
JPH0647016B2 (ja) 1994-06-22
AU1098488A (en) 1988-08-11
AU608278B2 (en) 1991-03-28
CA1317879C (en) 1993-05-18
ATE135928T1 (de) 1996-04-15

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