MX162176A - Procedimiento para preparar metil-ester de alfa-l-aspartil-l-fenilalanina o clorhidrato del mismo - Google Patents

Procedimiento para preparar metil-ester de alfa-l-aspartil-l-fenilalanina o clorhidrato del mismo

Info

Publication number
MX162176A
MX162176A MX2004A MX200486A MX162176A MX 162176 A MX162176 A MX 162176A MX 2004 A MX2004 A MX 2004A MX 200486 A MX200486 A MX 200486A MX 162176 A MX162176 A MX 162176A
Authority
MX
Mexico
Prior art keywords
aspartil
chlorhydrate
procedure
methyl ester
phenylalanine methyl
Prior art date
Application number
MX2004A
Other languages
English (en)
Inventor
Ryuchi Mita
Takeshi Oura
Toshio Katoh
Chojiro Higuchi
Akihiro Yamaguchi
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP60066097A external-priority patent/JPS61225196A/ja
Priority claimed from JP60066665A external-priority patent/JPH0751596B2/ja
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of MX162176A publication Critical patent/MX162176A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
MX2004A 1985-03-29 1986-03-26 Procedimiento para preparar metil-ester de alfa-l-aspartil-l-fenilalanina o clorhidrato del mismo MX162176A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP60066097A JPS61225196A (ja) 1985-03-29 1985-03-29 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製造法
JP60066665A JPH0751596B2 (ja) 1985-04-01 1985-04-01 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製造方法

Publications (1)

Publication Number Publication Date
MX162176A true MX162176A (es) 1991-04-05

Family

ID=26407276

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2004A MX162176A (es) 1985-03-29 1986-03-26 Procedimiento para preparar metil-ester de alfa-l-aspartil-l-fenilalanina o clorhidrato del mismo

Country Status (8)

Country Link
US (1) US4780561A (es)
EP (1) EP0196866A3 (es)
KR (1) KR890005039B1 (es)
AU (1) AU586669B2 (es)
BR (1) BR8601385A (es)
CA (1) CA1286845C (es)
ES (1) ES8708207A1 (es)
MX (1) MX162176A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3780585T2 (de) * 1986-12-05 1993-03-18 Mitsui Toatsu Chemicals Herstellung von alpha-l-aspartyl-l-phenylalanin-methylester oder deren hydrohalide.
US4897507A (en) * 1987-07-22 1990-01-30 Ajinomoto Co., Inc. Method for producing α-L-aspartyl-L-phenylalanine derivatives
US4992552A (en) * 1988-08-31 1991-02-12 Eastman Kodak Company Process for preparation of amino acids
US5144073A (en) * 1988-08-31 1992-09-01 Hubbs John C Process for preparation of dipeptides
ES2091324T3 (es) * 1990-03-15 1996-11-01 Nutrasweet Co Proceso para la preparacion de aspartama a partir de una dicetopiperazina y nuevos compuestos intermedios y derivados para dicho proceso.
JPH05117246A (ja) * 1991-10-23 1993-05-14 Ajinomoto Co Inc 新規２，５−ジオキソピペラジン化合物とその製造法及びα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル誘導体の製造法
JPH05194587A (ja) * 1992-01-14 1993-08-03 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの精製法
CN105315327A (zh) * 2014-08-04 2016-02-10 南京集美新型材料研发有限公司 2-（5-苄基-3,6-二酮哌嗪-2-基）乙酸和2-（5-苄基-3,6-二酮哌嗪-2-基）乙酸甲酯转化的方法
CN105315328A (zh) * 2014-08-04 2016-02-10 南京集美新型材料研发有限公司 N-α-L-天冬氨酞-L-苯丙1-氨酸甲酯中去除杂质的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS461370Y1 (es) * 1966-05-25 1971-01-19
JPS5113737A (en) * 1974-07-23 1976-02-03 Ajinomoto Kk Arufua ll asuparuchiru ll fueniruaraninteikyuarukiruesuteruno seizoho
US4088649A (en) * 1975-07-02 1978-05-09 Firmenich S.A. Process for preparing a diketo-piperazine
US4173562A (en) * 1976-12-27 1979-11-06 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester
MX4704E (es) * 1976-12-27 1982-08-04 Monsanto Co Procedimiento mejorado para la preparacion de ester metilico de alfa-l-aspartil-l-fenilalanina
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法
GB8300810D0 (en) * 1983-01-13 1983-02-16 Erba Farmitalia Aspartame synthesis
JPS59219258A (ja) * 1983-05-28 1984-12-10 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法
US4618695A (en) * 1983-06-02 1986-10-21 Ajinomoto Co., Inc. Method of preparing methyl ester and its hydrochloride
JPH0613550B2 (ja) * 1983-06-03 1994-02-23 味の素株式会社 α―Ｌ―アスパルチル―Ｌ―フェニルアラニン―低級アルキルエステルの製造法
JPS59227849A (ja) * 1983-06-08 1984-12-21 Ajinomoto Co Inc Ｌ―α―アスパルチル―Ｌ―フェニルアラニンメチルエステル束状晶の晶析分離法
JPS60174799A (ja) * 1984-02-21 1985-09-09 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法

Also Published As

Publication number Publication date
CA1286845C (en) 1991-07-23
EP0196866A2 (en) 1986-10-08
KR860007284A (ko) 1986-10-10
US4780561A (en) 1988-10-25
ES553331A0 (es) 1987-10-16
AU5493186A (en) 1986-10-02
AU586669B2 (en) 1989-07-20
EP0196866A3 (en) 1988-03-23
ES8708207A1 (es) 1987-10-16
BR8601385A (pt) 1986-12-02
KR890005039B1 (ko) 1989-12-08

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