ME03384B - Brzodjelujući pripravci inzulina - Google Patents

Brzodjelujući pripravci inzulina

Info

Publication number
ME03384B
ME03384B MEP-2019-126A MEP2019126A ME03384B ME 03384 B ME03384 B ME 03384B ME P2019126 A MEP2019126 A ME P2019126A ME 03384 B ME03384 B ME 03384B
Authority
ME
Montenegro
Prior art keywords
fast
acting insulin
insulin compositions
compositions
acting
Prior art date
Application number
MEP-2019-126A
Other languages
German (de)
English (en)
French (fr)
Inventor
Michael Edward Christe
Thomas Andrew Hardy
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53189204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME03384(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ME03384B publication Critical patent/ME03384B/me

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MEP-2019-126A 2014-05-08 2015-05-04 Brzodjelujući pripravci inzulina ME03384B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461990402P 2014-05-08 2014-05-08
EP15723388.3A EP3140008B1 (en) 2014-05-08 2015-05-04 Rapid-acting insulin compositions
PCT/US2015/029010 WO2015171484A1 (en) 2014-05-08 2015-05-04 Rapid-acting insulin compositions

Publications (1)

Publication Number Publication Date
ME03384B true ME03384B (me) 2020-01-20

Family

ID=53189204

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2019-126A ME03384B (me) 2014-05-08 2015-05-04 Brzodjelujući pripravci inzulina

Country Status (36)

Country Link
US (2) US9439952B2 (me)
EP (3) EP3140008B1 (me)
JP (1) JP6050902B2 (me)
KR (1) KR101858890B1 (me)
CN (1) CN106456717B (me)
AP (1) AP2016009525A0 (me)
AR (1) AR100155A1 (me)
AU (1) AU2015256355B2 (me)
BR (1) BR112016024357B1 (me)
CA (1) CA2945188C (me)
CL (1) CL2016002772A1 (me)
CY (2) CY1121669T1 (me)
DK (2) DK3140008T3 (me)
EA (1) EA031134B1 (me)
ES (2) ES2733639T3 (me)
HR (2) HRP20190777T1 (me)
HU (2) HUE044370T2 (me)
IL (1) IL248350B (me)
JO (1) JO3624B1 (me)
LT (2) LT3140008T (me)
MA (1) MA39441A1 (me)
ME (1) ME03384B (me)
MX (1) MX367521B (me)
NZ (1) NZ724919A (me)
PE (1) PE20161408A1 (me)
PH (1) PH12016502195A1 (me)
PL (2) PL3140008T3 (me)
PT (2) PT3140008T (me)
RS (2) RS58726B1 (me)
SG (1) SG11201608424WA (me)
SI (2) SI3536380T1 (me)
TN (1) TN2016000443A1 (me)
TR (1) TR201906843T4 (me)
TW (1) TWI685348B (me)
UA (1) UA124919C2 (me)
WO (1) WO2015171484A1 (me)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2910570T3 (pl) 2008-03-18 2017-06-30 Novo Nordisk A/S Stabilizowane względem proteaz, acylowane analogi insuliny
EP2919804B1 (fr) 2012-11-13 2018-01-31 Adocia Formulation à action rapide d'insuline comprenant un composé anionique substitué
WO2014110491A1 (en) 2013-01-11 2014-07-17 Theratrophix Llc Prodrugs of treprostinil
US9505737B2 (en) 2013-01-11 2016-11-29 Corsair Pharma, Inc. Treprostinil derivative compounds and methods of using same
WO2017015760A1 (en) * 2015-07-28 2017-02-02 Societe De Commercialisation Des Produits De La Recherche Appliquee Socpra Sciences Sante Et Humaines, S.E.C. A pharmaceutical preparation for improving absorption and postprandial hypoglycemic action of insulin
JO3749B1 (ar) * 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
EP3407870B1 (en) * 2016-01-29 2022-06-29 MannKind Corporation Dry powder inhaler
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
US20180153847A1 (en) 2016-09-26 2018-06-07 United Therapeutics Corporation Treprostinil prodrugs
EP3518893A1 (en) 2016-09-29 2019-08-07 Arecor Limited Novel formulations
CN115154591B (zh) 2016-12-16 2023-04-14 诺和诺德股份有限公司 含胰岛素的药物组合物
GB201707188D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707187D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707189D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
NZ758298A (en) * 2017-06-01 2022-11-25 Lilly Co Eli Rapid-acting insulin compositions
EP3773472A1 (en) 2018-04-04 2021-02-17 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
US12357562B2 (en) 2018-04-04 2025-07-15 Arecor Limited Injection pen system for the delivery of an insulin compound
EP3773473A1 (en) 2018-04-04 2021-02-17 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
ES2976468T3 (es) 2018-09-18 2024-08-01 Lilly Co Eli Sal de treprostinil erbumina
US10799564B1 (en) * 2019-05-06 2020-10-13 Baxter International Inc. Insulin premix formulation and product, methods of preparing same, and methods of using same
EP3996679B1 (en) * 2019-07-12 2023-09-06 Novo Nordisk A/S High concentration insulin formulation
US11634443B2 (en) 2019-08-23 2023-04-25 United Therapeutics Corporation Treprostinil prodrugs
GB202004814D0 (en) 2020-04-01 2020-05-13 Arecor Ltd Novel formulations
IL296567A (en) 2020-04-17 2022-11-01 United Therapeutics Corp Terfostinil for use in the treatment of interstitial lung disease
IL298591A (en) 2020-06-09 2023-01-01 United Therapeutics Corp Pomeryl dictopiperidine prodrugs of treprostinil
WO2022002008A1 (zh) * 2020-06-30 2022-01-06 江苏恒瑞医药股份有限公司 速效胰岛素组合物及其医药用途
EP4259121A1 (en) 2020-12-14 2023-10-18 United Therapeutics Corporation Methods of treating disease with treprostinil prodrugs
US12168071B2 (en) 2021-03-03 2024-12-17 United Therapeutics Corporation Treprostinil derivatives and their use in pharmaceutical compositions
WO2023206444A1 (zh) * 2022-04-29 2023-11-02 兆科药业(广州)有限公司 一种曲前列尼尔软雾吸入剂

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2740953A1 (de) 1977-09-12 1979-03-22 Thera Ges Fuer Patente Verwendung von prostaglandinen zur senkung des blutzuckerspiegels
JPH10251146A (ja) 1997-03-11 1998-09-22 Toray Ind Inc 糖尿病性神経障害の治療方法
CA2452044A1 (en) * 2001-08-28 2003-03-13 Eli Lilly And Company Pre-mixes of glp-1 and basal insulin
ES2360182T3 (es) * 2002-05-07 2011-06-01 Novo Nordisk A/S Formulaciones solubles que comprenden insulina monomérica e insulina acilada.
CN101287457B (zh) * 2004-04-12 2011-11-16 联合治疗公司 Treprostinil用于治疗神经性糖尿病的足部溃疡的用途
EP2190433A2 (en) * 2007-08-22 2010-06-02 Gilead Colorado, Inc. Therapy for complications of diabetes
EP2626093B1 (en) 2008-08-28 2014-02-12 Medingo Ltd. Device for enhanced subcutaneous insulin absorption
WO2010036798A1 (en) * 2008-09-25 2010-04-01 Aradigm Corporation Deep lung pulmonary delivery of treprostinil
EP2340033B1 (en) 2009-06-26 2013-10-09 Novo Nordisk A/S PREPARATION COMPRISING INSULIN, NICOTINAMIDE AND Arginine
BR112012011237A2 (pt) * 2009-11-13 2019-09-24 Univ Tokyo agente terapêutico e profilático para diabetes
BR112013014856A2 (pt) 2010-12-14 2016-10-18 Novo Nordisk As preparação compreendendo insulina, nicotinamida e um aminoácido
IN2014CN00989A (me) * 2011-08-12 2015-04-10 Ascendis Pharma As
US9381247B2 (en) * 2012-04-16 2016-07-05 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
US20150065423A1 (en) 2013-08-30 2015-03-05 Perosphere, Inc. Rapid acting injectable formulations
US20150273022A1 (en) 2014-02-10 2015-10-01 Biodel Inc. Stabilized ultra-rapid-acting insulin formulations

Also Published As

Publication number Publication date
CY1121669T1 (el) 2020-07-31
PL3536380T3 (pl) 2021-12-27
PH12016502195B1 (en) 2017-02-06
EP3536380B8 (en) 2021-09-22
EP3536380B1 (en) 2021-07-07
HRP20211415T1 (hr) 2021-12-10
IL248350A0 (en) 2016-11-30
RS58726B1 (sr) 2019-06-28
SI3536380T1 (sl) 2021-09-30
CN106456717A (zh) 2017-02-22
UA124919C2 (uk) 2021-12-15
MX2016014643A (es) 2017-03-06
AU2015256355A1 (en) 2016-10-27
CL2016002772A1 (es) 2017-06-09
US20160367640A1 (en) 2016-12-22
PT3536380T (pt) 2021-09-02
US20160129087A1 (en) 2016-05-12
PH12016502195A1 (en) 2017-02-06
KR101858890B1 (ko) 2018-05-16
TR201906843T4 (tr) 2019-05-21
TWI685348B (zh) 2020-02-21
MX367521B (es) 2019-08-26
MA39441A1 (fr) 2017-06-30
IL248350B (en) 2020-03-31
LT3536380T (lt) 2021-08-10
EA031134B1 (ru) 2018-11-30
CA2945188A1 (en) 2015-11-12
CN106456717B (zh) 2020-01-17
EA201691911A1 (ru) 2017-02-28
TW201625291A (zh) 2016-07-16
RS62291B1 (sr) 2021-09-30
AR100155A1 (es) 2016-09-14
PL3140008T3 (pl) 2019-09-30
TN2016000443A1 (en) 2018-04-04
EP3140008B1 (en) 2019-04-17
ES2733639T3 (es) 2019-12-02
SI3140008T1 (sl) 2019-06-28
BR112016024357A2 (pt) 2017-10-10
US9439952B2 (en) 2016-09-13
EP3943155A1 (en) 2022-01-26
BR112016024357B1 (pt) 2022-08-23
DK3536380T3 (da) 2021-08-02
PT3140008T (pt) 2019-06-25
LT3140008T (lt) 2019-05-27
HUE055742T2 (hu) 2021-12-28
PE20161408A1 (es) 2016-12-28
DK3140008T3 (da) 2019-06-24
US10172922B2 (en) 2019-01-08
CY1124454T1 (el) 2022-07-22
JO3624B1 (ar) 2020-08-27
JP2016523807A (ja) 2016-08-12
NZ724919A (en) 2018-01-26
AP2016009525A0 (en) 2016-10-31
ES2891983T3 (es) 2022-02-01
SG11201608424WA (en) 2016-11-29
AU2015256355B2 (en) 2017-09-14
KR20160133567A (ko) 2016-11-22
JP6050902B2 (ja) 2016-12-21
CA2945188C (en) 2018-12-11
EP3536380A1 (en) 2019-09-11
EP3140008A1 (en) 2017-03-15
WO2015171484A1 (en) 2015-11-12
HUE044370T2 (hu) 2019-10-28
HRP20190777T1 (hr) 2019-08-23

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