ME02017B - Jedinjenja, kompozicije i postupci za tretman beta-amiloidnih bolesti i sinukleinopatija - Google Patents
Jedinjenja, kompozicije i postupci za tretman beta-amiloidnih bolesti i sinukleinopatijaInfo
- Publication number
- ME02017B ME02017B MEP-2014-129A MEP12914A ME02017B ME 02017 B ME02017 B ME 02017B ME P12914 A MEP12914 A ME P12914A ME 02017 B ME02017 B ME 02017B
- Authority
- ME
- Montenegro
- Prior art keywords
- synucleinopathy
- beta
- procedures
- compositions
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/11—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
- C07C37/16—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms by condensation involving hydroxy groups of phenols or alcohols or the ether or mineral ester group derived therefrom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
- C07C39/10—Polyhydroxy benzenes; Alkylated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
- C07C39/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/244,968 US8829198B2 (en) | 2007-10-31 | 2008-10-03 | Compounds, compositions and methods for the treatment of beta-amyloid diseases and synucleinopathies |
| EP09818145.6A EP2328417B1 (en) | 2008-10-03 | 2009-06-26 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF beta-AMYLOID DISEASES AND SYNUCLEINOPATHIES |
| PCT/US2009/048855 WO2010039308A1 (en) | 2008-10-03 | 2009-06-26 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF β-AMYLOID DISEASES AND SYNUCLEINOPATHIES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ME02017B true ME02017B (me) | 2015-05-20 |
Family
ID=40583657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MEP-2014-129A ME02017B (me) | 2008-10-03 | 2009-06-26 | Jedinjenja, kompozicije i postupci za tretman beta-amiloidnih bolesti i sinukleinopatija |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US8829198B2 (me) |
| EP (1) | EP2328417B1 (me) |
| JP (1) | JP5431485B2 (me) |
| KR (1) | KR20110086549A (me) |
| CN (1) | CN102170787B (me) |
| AU (2) | AU2009300298A1 (me) |
| BR (1) | BRPI0920687A2 (me) |
| CA (1) | CA2735120C (me) |
| CL (1) | CL2011000739A1 (me) |
| CO (1) | CO6382089A2 (me) |
| CY (1) | CY1115725T1 (me) |
| DK (1) | DK2328417T3 (me) |
| ES (1) | ES2519140T3 (me) |
| HR (1) | HRP20140967T1 (me) |
| IL (1) | IL211313A (me) |
| MA (1) | MA32686B1 (me) |
| ME (1) | ME02017B (me) |
| MX (1) | MX2011002830A (me) |
| MY (1) | MY156302A (me) |
| NZ (1) | NZ591504A (me) |
| PE (1) | PE20110930A1 (me) |
| PL (1) | PL2328417T3 (me) |
| PT (1) | PT2328417E (me) |
| RS (1) | RS53613B1 (me) |
| RU (1) | RU2501792C2 (me) |
| SI (1) | SI2328417T1 (me) |
| UA (1) | UA101393C2 (me) |
| WO (1) | WO2010039308A1 (me) |
| ZA (1) | ZA201101278B (me) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009111611A2 (en) * | 2008-03-05 | 2009-09-11 | Proteotech Inc. | Compounds, compositions and methods for the treatment of islet amyloid polypeptide (iapp) accumulation in diabetes |
| ES2714453T3 (es) * | 2008-06-09 | 2019-05-28 | Univ Muenchen Ludwig Maximilians | Fármacos para inhibir la agregación de proteínas implicadas en enfermedades relacionadas con enfermedades neurodegenerativas y/o agregación de proteínas |
| EP2509590B1 (en) * | 2009-12-10 | 2019-10-30 | The Trustees of Columbia University in the City of New York | Histone acetyltransferase activators and uses thereof |
| US10640457B2 (en) | 2009-12-10 | 2020-05-05 | The Trustees Of Columbia University In The City Of New York | Histone acetyltransferase activators and uses thereof |
| US20120251448A1 (en) * | 2011-03-03 | 2012-10-04 | Hefti Franz F | Compounds for Use in the Detection of Neurodegenerative Diseases |
| GB201512203D0 (en) | 2015-07-13 | 2015-08-19 | Lundbeck & Co As H | Agents,uses and methods |
| RU2614697C1 (ru) * | 2016-04-12 | 2017-03-28 | Общество с ограниченной ответственностью "Нормофарм" | Нейропротекторное средство |
| RU2019114679A (ru) | 2016-11-15 | 2020-12-17 | Х. Лундбекк А/С | Средства, пути применения и способы лечения синуклеопатии |
| EP3555127B1 (en) | 2016-12-16 | 2024-12-18 | H. Lundbeck A/S | Agents, uses and methods |
| WO2020163704A1 (en) * | 2019-02-07 | 2020-08-13 | Alsatech, Inc. | Polyvalent derivatives of emoxypine |
| KR20220104000A (ko) * | 2019-11-19 | 2022-07-25 | 모다크 게엠베하 | 알파-시누클레인의 응집과 관련된 질병의 진단, 치료 및 예방을 위한 신규한 화합물 |
| CN114573570B (zh) * | 2022-02-21 | 2023-05-30 | 中山大学 | 一类α-突触核蛋白靶向化合物及其制备方法和应用 |
| CN115650957B (zh) * | 2022-09-16 | 2023-12-15 | 中山大学 | 一类靶向α-突触核蛋白的蛋白水解嵌合体及其应用 |
| EP4775203A1 (en) * | 2023-09-08 | 2026-07-15 | Theranocure Co., Ltd. | Vanillic acid derivative compound, therapeutic agent composition for alzheimer's disease comprising same, and therapeutic agent composition for neuroinflammation |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US4710384A (en) | 1986-07-28 | 1987-12-01 | Avner Rotman | Sustained release tablets made from microcapsules |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5585112A (en) | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
| IT1246382B (it) | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5543390A (en) | 1990-11-01 | 1996-08-06 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University | Covalent microparticle-drug conjugates for biological targeting |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5387681A (en) | 1992-08-19 | 1995-02-07 | Eli Lilly And Company | Synthesis of bicyclic aromatic sulfonic acids sulfonyl chlorides and sulfonamides |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| US6274552B1 (en) | 1993-03-18 | 2001-08-14 | Cytimmune Sciences, Inc. | Composition and method for delivery of biologically-active factors |
| US5523092A (en) | 1993-04-14 | 1996-06-04 | Emory University | Device for local drug delivery and methods for using the same |
| US5985307A (en) | 1993-04-14 | 1999-11-16 | Emory University | Device and method for non-occlusive localized drug delivery |
| JP3682075B2 (ja) * | 1993-04-16 | 2005-08-10 | クミアイ化学工業株式会社 | トリアゾール誘導体及び殺虫、殺ダニ剤 |
| US6004534A (en) | 1993-07-23 | 1999-12-21 | Massachusetts Institute Of Technology | Targeted polymerized liposomes for improved drug delivery |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US5759542A (en) | 1994-08-05 | 1998-06-02 | New England Deaconess Hospital Corporation | Compositions and methods for the delivery of drugs by platelets for the treatment of cardiovascular and other diseases |
| US5660854A (en) | 1994-11-28 | 1997-08-26 | Haynes; Duncan H | Drug releasing surgical implant or dressing material |
| US6316652B1 (en) | 1995-06-06 | 2001-11-13 | Kosta Steliou | Drug mitochondrial targeting agents |
| US6039975A (en) | 1995-10-17 | 2000-03-21 | Hoffman-La Roche Inc. | Colon targeted delivery system |
| TW345603B (en) | 1996-05-29 | 1998-11-21 | Gmundner Fertigteile Gmbh | A noise control device for tracks |
| MY129541A (en) | 1996-06-25 | 2007-04-30 | Novartis Ag | Substituded 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators |
| WO1998014179A1 (en) | 1996-10-01 | 1998-04-09 | Cima Labs Inc. | Taste-masked microcapsule compositions and methods of manufacture |
| US6131570A (en) | 1998-06-30 | 2000-10-17 | Aradigm Corporation | Temperature controlling device for aerosol drug delivery |
| US6120751A (en) | 1997-03-21 | 2000-09-19 | Imarx Pharmaceutical Corp. | Charged lipids and uses for the same |
| US6060082A (en) | 1997-04-18 | 2000-05-09 | Massachusetts Institute Of Technology | Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery |
| US6288061B1 (en) | 1997-12-26 | 2001-09-11 | Welfide Corporation | Imidazole derivatives |
| JP2004067510A (ja) * | 1997-12-26 | 2004-03-04 | Mitsubishi Pharma Corp | 新規イミダゾール誘導体 |
| IT1300055B1 (it) | 1998-04-17 | 2000-04-05 | Boehringer Ingelheim Italia | Eterocicli con anello a 5 termini difenil-sostituiti loro procedimento di preparazione e loro impiego come farmici |
| US6048736A (en) | 1998-04-29 | 2000-04-11 | Kosak; Kenneth M. | Cyclodextrin polymers for carrying and releasing drugs |
| US6271359B1 (en) | 1999-04-14 | 2001-08-07 | Musc Foundation For Research Development | Tissue-specific and pathogen-specific toxic agents and ribozymes |
| WO2003053986A1 (en) | 2001-12-21 | 2003-07-03 | Ciba Specialty Chemicals Holding Inc. | Use of metal complex compounds as oxidation catalysts |
| US20070276034A1 (en) | 2002-05-31 | 2007-11-29 | Luke Esposito | Compounds, compositions and methods for the treatment of synucleinopathies |
| PT1511710E (pt) * | 2002-05-31 | 2014-02-26 | Proteotech Inc | Compostos, composições e métodos para o tratamento de doenças da amiloide e sinucleínopatias tais como doença de alzheimer, diabetes do tipo 2, e doença de parkinson |
| JP4537855B2 (ja) * | 2002-10-09 | 2010-09-08 | 久光製薬株式会社 | 抗真菌活性を有する新規ピラゾール化合物 |
| EP1603548A4 (en) | 2003-02-05 | 2007-10-10 | Myriad Genetics Inc | METHOD AND COMPOSITION FOR THE TREATMENT OF NEURODEEGENERATIVE DISEASES |
| US8916598B2 (en) * | 2003-05-30 | 2014-12-23 | Proteotech Inc | Compounds, compositions, and methods for the treatment of β-amyloid diseases and synucleinopathies |
| WO2005006945A2 (en) | 2003-07-03 | 2005-01-27 | The Salk Institute For Biological Studies | Methods for treating neural disorders and compounds useful therefor |
| US8193389B2 (en) | 2004-03-11 | 2012-06-05 | Elan Pharmaceuticals, Inc. | N-substituted benzene sulfonamides |
| CN101111237A (zh) | 2005-02-10 | 2008-01-23 | 诺瓦提斯公司 | 改善药物处置的方法 |
| EP1879548A2 (en) | 2005-05-13 | 2008-01-23 | Ciba Specialty Chemicals Holding Inc. | Process for coloring keratin fibers comprising metal complexes |
| PL1945272T3 (pl) | 2005-11-01 | 2014-03-31 | Novartis Ag | Sposób prowadzenia scyntygraffi |
| CN101500561A (zh) | 2006-08-04 | 2009-08-05 | 诺瓦提斯公司 | 应用铁螯合剂治疗内分泌功能障碍 |
| KR20100016512A (ko) | 2007-05-14 | 2010-02-12 | 노파르티스 아게 | 심근경색증 치료를 위한 철 킬레이터의 용도 |
| EP1994930A1 (en) | 2007-05-22 | 2008-11-26 | Novartis AG | Triazol compounds for treating biofilm formation |
| WO2009111611A2 (en) | 2008-03-05 | 2009-09-11 | Proteotech Inc. | Compounds, compositions and methods for the treatment of islet amyloid polypeptide (iapp) accumulation in diabetes |
| ES2714453T3 (es) | 2008-06-09 | 2019-05-28 | Univ Muenchen Ludwig Maximilians | Fármacos para inhibir la agregación de proteínas implicadas en enfermedades relacionadas con enfermedades neurodegenerativas y/o agregación de proteínas |
-
2008
- 2008-10-03 US US12/244,968 patent/US8829198B2/en not_active Expired - Fee Related
-
2009
- 2009-06-26 CN CN200980139183.2A patent/CN102170787B/zh not_active Expired - Fee Related
- 2009-06-26 PT PT98181456T patent/PT2328417E/pt unknown
- 2009-06-26 BR BRPI0920687-6A patent/BRPI0920687A2/pt not_active IP Right Cessation
- 2009-06-26 ES ES09818145.6T patent/ES2519140T3/es active Active
- 2009-06-26 RU RU2011117544/04A patent/RU2501792C2/ru not_active IP Right Cessation
- 2009-06-26 MX MX2011002830A patent/MX2011002830A/es active IP Right Grant
- 2009-06-26 AU AU2009300298A patent/AU2009300298A1/en not_active Abandoned
- 2009-06-26 SI SI200931042T patent/SI2328417T1/sl unknown
- 2009-06-26 UA UAA201103613A patent/UA101393C2/ru unknown
- 2009-06-26 ME MEP-2014-129A patent/ME02017B/me unknown
- 2009-06-26 HR HRP20140967AT patent/HRP20140967T1/hr unknown
- 2009-06-26 EP EP09818145.6A patent/EP2328417B1/en active Active
- 2009-06-26 RS RS20140546A patent/RS53613B1/sr unknown
- 2009-06-26 PE PE2011000835A patent/PE20110930A1/es not_active Application Discontinuation
- 2009-06-26 WO PCT/US2009/048855 patent/WO2010039308A1/en not_active Ceased
- 2009-06-26 PL PL09818145T patent/PL2328417T3/pl unknown
- 2009-06-26 CA CA2735120A patent/CA2735120C/en not_active Expired - Fee Related
- 2009-06-26 DK DK09818145.6T patent/DK2328417T3/da active
- 2009-06-26 KR KR1020117007553A patent/KR20110086549A/ko not_active Ceased
- 2009-06-26 JP JP2011530077A patent/JP5431485B2/ja not_active Expired - Fee Related
- 2009-06-26 NZ NZ591504A patent/NZ591504A/xx not_active IP Right Cessation
- 2009-06-26 MY MYPI2011001173A patent/MY156302A/en unknown
-
2011
- 2011-02-17 ZA ZA2011/01278A patent/ZA201101278B/en unknown
- 2011-02-20 IL IL211313A patent/IL211313A/en not_active IP Right Cessation
- 2011-04-01 CL CL2011000739A patent/CL2011000739A1/es unknown
- 2011-04-01 MA MA33735A patent/MA32686B1/fr unknown
- 2011-04-11 CO CO11044322A patent/CO6382089A2/es active IP Right Grant
-
2012
- 2012-04-26 US US13/456,691 patent/US8592476B2/en not_active Expired - Fee Related
-
2014
- 2014-11-11 CY CY20141100934T patent/CY1115725T1/el unknown
-
2016
- 2016-03-17 AU AU2016201693A patent/AU2016201693A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL251768A0 (en) | Auris formulations for treating otic diseases and conditions | |
| HUE039731T2 (hu) | l,3-difenilprop-2-én-l-on-származékok alkalmazása májbetegségek kezelésére | |
| PL3354276T3 (pl) | Kompozycje do leczenia zapalenia przewodu pokarmowego | |
| BRPI0908026A2 (pt) | Métodos para o tratamento de doenças do intestino | |
| CY2014006I2 (el) | Μεθοδοι θεραπευτικης αγωγης χρησιμοποιωντας γλυκοπεγκυλιωμενο g-csf | |
| GB0802403D0 (en) | Compositions for the treatment of oxidative stress | |
| SI2328417T1 (sl) | Spojine, sestavki in postopki za zdravljenje beta amiloidnih bolezni in sinukleinopatije | |
| PL2338519T3 (pl) | Środek do leczenia zwłóknienia szpiku | |
| IL208354A0 (en) | Methods of treatment | |
| ME03508B (me) | Kombinovana terapija za liječenje dijabetesa | |
| AP2011005682A0 (en) | Multiheteroaryl compounds as inhibitors of H-PGDS and their use for treating prostaglandin D2 mediated diseases. | |
| BRPI0815551A2 (pt) | Tratamento através de hucbc de doença beta-amiloide | |
| PL2435825T3 (pl) | Sposoby leczenia chorób | |
| IL208357A0 (en) | Spiro-indole derivatives for the treatment of parasitic diseases | |
| EP2257569A4 (en) | METHOD OF TREATMENT USING ANTIMICROBIAL COMPOSITION | |
| ZA201201802B (en) | Composition for treatment of cxcl8-mediated lung inflammation | |
| ITTO20110630A1 (it) | Composizioni farmaceutiche di combinazione e metodo per trattare vertigini, cinetosi e distonia vascolare vegetativa | |
| ZA201106577B (en) | Compounds and compositions for cognition-enhancement,methods of making,and methods of treating | |
| GB0902040D0 (en) | Composition for treatment of skin | |
| FI20095600L (fi) | Koostumus ihosairauksien hoitoa varten | |
| DK2296651T3 (da) | 5-hydroxymethyl-oxazolidin-2-on-derivater til behandling af bakterielle intestinale sygdomme | |
| BRPI0811575A2 (pt) | Composição contendo vesículas e método de produção da mesma | |
| EP2563120A4 (en) | METHOD, COMPOSITIONS AND KITS FOR PROVIDING THERAPEUTIC TREATMENT | |
| DK2331092T3 (da) | Fremgangsmåder og sammensætninger til indgivelse af 3-halopyruvat og associerede forbindelser til behandling af cancer | |
| EP2515652A4 (en) | COMPOSITIONS AND METHODS FOR TREATING VITILIGO |