ME01758B - Humanizirano protutijelo protiv amiloida beta - Google Patents
Humanizirano protutijelo protiv amiloida betaInfo
- Publication number
- ME01758B ME01758B MEP-2013-132A MEP13213A ME01758B ME 01758 B ME01758 B ME 01758B ME P13213 A MEP13213 A ME P13213A ME 01758 B ME01758 B ME 01758B
- Authority
- ME
- Montenegro
- Prior art keywords
- humanized antibody
- antibody against
- amyloid beta
- against amyloid
- beta
- Prior art date
Links
- 102000013455 Amyloid beta-Peptides Human genes 0.000 title 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06014730 | 2006-07-14 | ||
EP06020765 | 2006-10-02 | ||
US94328907P | 2007-06-11 | 2007-06-11 | |
US94349907P | 2007-06-12 | 2007-06-12 | |
PCT/US2007/073504 WO2008011348A2 (fr) | 2006-07-14 | 2007-07-13 | Anticorps humanisé |
EP07840408.4A EP2046833B9 (fr) | 2006-07-14 | 2007-07-13 | Anticorps humanisé contre l'amyloid beta |
Publications (1)
Publication Number | Publication Date |
---|---|
ME01758B true ME01758B (me) | 2014-09-20 |
Family
ID=49474825
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2013-132A ME01758B (me) | 2006-07-14 | 2007-07-13 | Humanizirano protutijelo protiv amiloida beta |
MEP-2010-59A ME01075B (fr) | 2006-07-14 | 2007-07-13 | Anticorps humanisé |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2010-59A ME01075B (fr) | 2006-07-14 | 2007-07-13 | Anticorps humanisé |
Country Status (22)
Country | Link |
---|---|
US (2) | US20160272699A1 (fr) |
EP (1) | EP3309172B1 (fr) |
KR (6) | KR20170098978A (fr) |
CN (3) | CN106831983B (fr) |
BR (1) | BRPI0714713B1 (fr) |
CR (1) | CR20140496A (fr) |
CY (1) | CY1114604T1 (fr) |
DK (2) | DK2468770T3 (fr) |
ES (2) | ES2661562T3 (fr) |
HU (1) | HUE038438T2 (fr) |
IL (1) | IL254065B (fr) |
LT (1) | LT2468770T (fr) |
ME (2) | ME01758B (fr) |
MY (2) | MY165105A (fr) |
NZ (1) | NZ607881A (fr) |
PH (1) | PH12012501882A1 (fr) |
PT (2) | PT2046833E (fr) |
RS (2) | RS53160B (fr) |
RU (1) | RU2668161C2 (fr) |
SI (2) | SI2468770T1 (fr) |
TR (1) | TR201802814T4 (fr) |
TW (2) | TWI608014B (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6081356B2 (ja) * | 2010-07-30 | 2017-02-15 | エーシー イミューン エス.エー. | 安全で機能的なヒト化抗βアミロイド抗体 |
SI3166970T1 (sl) * | 2014-07-10 | 2021-09-30 | Bioarctic Ab | Izboljšana A-beta protofibril vezavna protitelesa |
US20200308259A1 (en) * | 2016-06-07 | 2020-10-01 | Biogen International Neuroscience Gmbh | Methods for treating alzheimer's disease |
KR20190098741A (ko) | 2016-11-01 | 2019-08-22 | 아납티스바이오, 아이엔씨. | T 세포 면역글로불린 및 뮤신 단백질 3(tim-3)에 대한 항체 |
WO2018129553A1 (fr) | 2017-01-09 | 2018-07-12 | Tesaro, Inc. | Méthodes de traitement du cancer au moyen d'anticorps anti-tim-3 |
US12018069B2 (en) | 2018-06-28 | 2024-06-25 | The Trustees Of Columbia University In The City Of New York | Methods and compositions for imaging amyloid deposits |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
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US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
JPS6412935A (en) | 1987-07-02 | 1989-01-17 | Mitsubishi Electric Corp | Constant-speed travel device for vehicle |
US5004697A (en) | 1987-08-17 | 1991-04-02 | Univ. Of Ca | Cationized antibodies for delivery through the blood-brain barrier |
US5843708A (en) | 1988-01-05 | 1998-12-01 | Ciba-Geigy Corporation | Chimeric antibodies |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5268164A (en) | 1990-04-23 | 1993-12-07 | Alkermes, Inc. | Increasing blood-brain barrier permeability with permeabilizer peptides |
US5112596A (en) | 1990-04-23 | 1992-05-12 | Alkermes, Inc. | Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability |
US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
CA2141216A1 (fr) | 1992-07-27 | 1994-02-03 | Michael J. Micklus | Ciblage de liposomes vers la barriere hemato-encephalique |
US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
JPH10507643A (ja) | 1994-10-21 | 1998-07-28 | イノジェネティックス・ナムローゼ・フェンノートシャップ | C型肝炎ウイルス遺伝子型の新規配列、ならびにそれらの予防薬、治療薬および診断薬としての使用 |
US5756662A (en) | 1995-03-14 | 1998-05-26 | Corixa Corporation | Compounds and methods for the detection of T. cruzi infection |
US6632976B1 (en) | 1995-08-29 | 2003-10-14 | Kirin Beer Kabushiki Kaisha | Chimeric mice that are produced by microcell mediated chromosome transfer and that retain a human antibody gene |
CZ295118B6 (cs) * | 1996-08-13 | 2005-05-18 | P. N. Gerolymatos S. A. | Farmaceutický prostředek |
US7179892B2 (en) * | 2000-12-06 | 2007-02-20 | Neuralab Limited | Humanized antibodies that recognize beta amyloid peptide |
US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
PT1071700E (pt) | 1998-04-20 | 2010-04-23 | Glycart Biotechnology Ag | Modificação por glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos |
CN1433321A (zh) * | 1999-11-29 | 2003-07-30 | 尼奥切姆公司 | 预防和治疗Alzheimer症和其他与淀粉样蛋白有关的疾病的疫苗 |
US20020094335A1 (en) * | 1999-11-29 | 2002-07-18 | Robert Chalifour | Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases |
BRPI0108676B8 (pt) * | 2000-02-24 | 2021-05-25 | Lilly Co Eli | anticorpos humanizados que sequestram peptídeo amilóide beta e seus usos no tratamento de condições caracterizadas por formação de placas amiloides, bem como composição farmacêutica que compreende os referidos anticorpos |
US6514221B2 (en) | 2000-07-27 | 2003-02-04 | Brigham And Women's Hospital, Inc. | Blood-brain barrier opening |
AU2001286930A1 (en) | 2000-08-30 | 2002-03-13 | The Board Of Trustees Of The Leland Stanford Junior University | Glucocorticoid blocking agents for increasing blood-brain barrier permeability |
US7034036B2 (en) | 2000-10-30 | 2006-04-25 | Pain Therapeutics, Inc. | Inhibitors of ABC drug transporters at the blood-brain barrier |
US20030083299A1 (en) | 2000-11-04 | 2003-05-01 | Ferguson Ian A. | Non-invasive delivery of polypeptides through the blood-brain barrier |
DE10121982B4 (de) | 2001-05-05 | 2008-01-24 | Lts Lohmann Therapie-Systeme Ag | Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung |
DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
CA2838062C (fr) | 2001-08-03 | 2015-12-22 | Roche Glycart Ag | Variants de glycosylation d'anticorps presentant une cytotoxicite cellulaire accrue dependante des anticorps |
EP1448601A4 (fr) * | 2001-11-02 | 2006-04-26 | Diagenics Internat Corp | Methodes et compositions d'anticorps monoclonaux specifiques des proteines beta-amyloides |
AR038568A1 (es) * | 2002-02-20 | 2005-01-19 | Hoffmann La Roche | Anticuerpos anti-a beta y su uso |
US20030162695A1 (en) | 2002-02-27 | 2003-08-28 | Schatzberg Alan F. | Glucocorticoid blocking agents for increasing blood-brain barrier permeability |
KR101111477B1 (ko) | 2002-12-03 | 2012-02-23 | 블랜체트 록펠러 뉴로사이언시즈 인스티튜트 | 치료제와 연결된 콜레스테롤을 포함하는 접합체 |
JP2006512417A (ja) | 2002-12-24 | 2006-04-13 | ニューロケム (インターナショナル) リミテッド | β−アミロイド関連疾患の治療のための治療用製剤 |
US7575747B2 (en) * | 2003-02-10 | 2009-08-18 | Applied Molecular Evolution | Aβ binding molecules |
US20050089473A1 (en) | 2003-09-10 | 2005-04-28 | Cedars-Sinai Medical Center | Potassium channel mediated delivery of agents through the blood-brain barrier |
AU2005306997B2 (en) * | 2004-10-25 | 2012-07-05 | Merck Sharp & Dohme Corp. | Anti-ADDL antibodies and uses thereof |
CA2790433A1 (fr) * | 2004-10-25 | 2006-05-26 | Northwestern University | Anticorps anti-addl et leurs utilisations |
TW200635608A (en) * | 2004-12-15 | 2006-10-16 | Neuralab Ltd | Aβ antibodies for use in improving cognition |
DK1976877T4 (en) * | 2005-11-30 | 2017-01-16 | Abbvie Inc | Monoclonal antibodies to amyloid beta protein and uses thereof |
RU2551782C2 (ru) * | 2005-12-12 | 2015-05-27 | Ац Иммуне Са | Специфические в отношении амилоида бета (а бета) 1-42 моноклональные антитела, обладающие терапевтическими свойствами |
CN101058608B (zh) * | 2006-04-21 | 2011-02-23 | 杜如昱 | 人类抗Aβ1-32淀粉样蛋白抗体、其纯化方法及用途 |
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2007
- 2007-07-13 LT LTEP11192705.9T patent/LT2468770T/lt unknown
- 2007-07-13 ES ES11192705.9T patent/ES2661562T3/es active Active
- 2007-07-13 SI SI200732012T patent/SI2468770T1/en unknown
- 2007-07-13 RS RS20130515A patent/RS53160B/en unknown
- 2007-07-13 DK DK11192705.9T patent/DK2468770T3/en active
- 2007-07-13 PT PT78404084T patent/PT2046833E/pt unknown
- 2007-07-13 CN CN201610907892.2A patent/CN106831983B/zh active Active
- 2007-07-13 EP EP17190333.9A patent/EP3309172B1/fr active Active
- 2007-07-13 KR KR1020177023161A patent/KR20170098978A/ko not_active Application Discontinuation
- 2007-07-13 TW TW103133840A patent/TWI608014B/zh active
- 2007-07-13 RS RS20180266A patent/RS56986B1/sr unknown
- 2007-07-13 NZ NZ607881A patent/NZ607881A/en unknown
- 2007-07-13 SI SI200731343T patent/SI2046833T1/sl unknown
- 2007-07-13 CN CN201310250243.6A patent/CN103524617B/zh active Active
- 2007-07-13 DK DK07840408.4T patent/DK2046833T5/en active
- 2007-07-13 KR KR1020187011457A patent/KR20180043854A/ko not_active Application Discontinuation
- 2007-07-13 PT PT111927059T patent/PT2468770T/pt unknown
- 2007-07-13 TW TW106126216A patent/TW201815827A/zh unknown
- 2007-07-13 ES ES07840408T patent/ES2436112T3/es active Active
- 2007-07-13 KR KR1020157019161A patent/KR20150087435A/ko not_active Application Discontinuation
- 2007-07-13 CN CN200780033976.7A patent/CN101516911B/zh active Active
- 2007-07-13 MY MYPI2012003696A patent/MY165105A/en unknown
- 2007-07-13 KR KR1020167034680A patent/KR20160147066A/ko not_active Application Discontinuation
- 2007-07-13 HU HUE11192705A patent/HUE038438T2/hu unknown
- 2007-07-13 TR TR2018/02814T patent/TR201802814T4/tr unknown
- 2007-07-13 KR KR1020197000092A patent/KR20190003862A/ko not_active Application Discontinuation
- 2007-07-13 ME MEP-2013-132A patent/ME01758B/me unknown
- 2007-07-13 BR BRPI0714713-9A patent/BRPI0714713B1/pt active IP Right Grant
- 2007-07-13 KR KR1020167010466A patent/KR20160049045A/ko not_active Application Discontinuation
- 2007-07-13 MY MYPI20090150A patent/MY153248A/en unknown
- 2007-07-13 ME MEP-2010-59A patent/ME01075B/fr unknown
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2012
- 2012-09-21 PH PH12012501882A patent/PH12012501882A1/en unknown
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2013
- 2013-04-05 RU RU2013115283A patent/RU2668161C2/ru active
- 2013-11-14 CY CY20131101015T patent/CY1114604T1/el unknown
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2014
- 2014-10-27 CR CR20140496A patent/CR20140496A/es unknown
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2015
- 2015-10-28 US US14/925,523 patent/US20160272699A1/en not_active Abandoned
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2017
- 2017-08-20 IL IL254065A patent/IL254065B/en active IP Right Grant
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2021
- 2021-08-04 US US17/394,033 patent/US20220227847A1/en active Pending
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PT2121751T (pt) | Anticorpos monoclonais contra angptl3 | |
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EP2198055A4 (fr) | Anticorps pai-1 humanisés | |
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GB0804684D0 (en) | Humanized antibody |