ME01469B - POLISUPSTITUISANI DERIVATI 2-ARIL-6-FENIL-IMIDAZO[1,2-a]PIRIDINA I NJIHOVO DOBIJANJE I TERAPEUTSKA UPOTREBA - Google Patents

POLISUPSTITUISANI DERIVATI 2-ARIL-6-FENIL-IMIDAZO[1,2-a]PIRIDINA I NJIHOVO DOBIJANJE I TERAPEUTSKA UPOTREBA

Info

Publication number
ME01469B
ME01469B MEP-2013-4A MEP413A ME01469B ME 01469 B ME01469 B ME 01469B ME P413 A MEP413 A ME P413A ME 01469 B ME01469 B ME 01469B
Authority
ME
Montenegro
Prior art keywords
pyridines
imidazo
aryl
phenyl
preparation
Prior art date
Application number
MEP-2013-4A
Other languages
English (en)
Inventor
Peretti Danielle De
Yannick Evanno
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39764893&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME01469(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ME01469B publication Critical patent/ME01469B/me

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
MEP-2013-4A 2008-03-21 2009-03-20 POLISUPSTITUISANI DERIVATI 2-ARIL-6-FENIL-IMIDAZO[1,2-a]PIRIDINA I NJIHOVO DOBIJANJE I TERAPEUTSKA UPOTREBA ME01469B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0801580A FR2928921B1 (fr) 2008-03-21 2008-03-21 Derives polysubstitues de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines, leur preparation et leur application en therapeutique
EP09754041A EP2262803B1 (fr) 2008-03-21 2009-03-20 Dérivés polysubstitues de 2-aryl-6-phenyl-imidazo[1,2- a]pyridines, leur préparation et leur application en thérapeutique
PCT/FR2009/000297 WO2009144391A1 (fr) 2008-03-21 2009-03-20 DÉRIVÉS POLYSUBSTITUES DE 2-ARYL-6-PHENYL-IMIDAZO[1,2- α]PYRIDINES, LEUR PRÉPARATION ET LEUR APPLICATION EN THÉRAPEUTIQUE

Publications (1)

Publication Number Publication Date
ME01469B true ME01469B (me) 2014-04-20

Family

ID=39764893

Family Applications (2)

Application Number Title Priority Date Filing Date
MEP-2010-151A ME01098B (me) 2008-03-21 2009-03-20 VIŠESTRUKO SUPSTITUISANI DERIVATI 2-ARIL-6-FENILIMIDAZO [1,2- α] PIRIDINA, I NJIHOVO DOBIJANJE I TERAPEUTSKA PRIMENA
MEP-2013-4A ME01469B (me) 2008-03-21 2009-03-20 POLISUPSTITUISANI DERIVATI 2-ARIL-6-FENIL-IMIDAZO[1,2-a]PIRIDINA I NJIHOVO DOBIJANJE I TERAPEUTSKA UPOTREBA

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MEP-2010-151A ME01098B (me) 2008-03-21 2009-03-20 VIŠESTRUKO SUPSTITUISANI DERIVATI 2-ARIL-6-FENILIMIDAZO [1,2- α] PIRIDINA, I NJIHOVO DOBIJANJE I TERAPEUTSKA PRIMENA

Country Status (30)

Country Link
US (1) US8148370B2 (me)
EP (1) EP2262803B1 (me)
JP (1) JP5508383B2 (me)
KR (1) KR20100129774A (me)
CN (1) CN102036988B (me)
AR (1) AR070992A1 (me)
AU (1) AU2009253231B2 (me)
BR (1) BRPI0908999A8 (me)
CA (1) CA2718953C (me)
CL (1) CL2009000695A1 (me)
CO (1) CO6300865A2 (me)
CY (1) CY1113549T1 (me)
DK (1) DK2262803T3 (me)
EA (1) EA018266B1 (me)
ES (1) ES2397931T3 (me)
FR (1) FR2928921B1 (me)
HR (1) HRP20130029T1 (me)
IL (1) IL208248A0 (me)
MA (1) MA32246B1 (me)
ME (2) ME01098B (me)
MX (1) MX2010010259A (me)
NZ (1) NZ588081A (me)
PE (1) PE20091818A1 (me)
PL (1) PL2262803T3 (me)
PT (1) PT2262803E (me)
RS (1) RS52652B (me)
SI (1) SI2262803T1 (me)
TW (1) TW201000477A (me)
UY (1) UY31727A (me)
WO (1) WO2009144391A1 (me)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2928923B1 (fr) * 2008-03-21 2010-04-23 Sanofi Aventis Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques
FR2928922B1 (fr) * 2008-03-21 2010-04-23 Sanofi Aventis Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
FR2928924B1 (fr) * 2008-03-21 2010-04-23 Sanofi Aventis Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique
FR2953520B1 (fr) * 2009-12-04 2011-11-25 Sanofi Aventis Derives de diphenyl-pyrazolopyridines, leur preparation et leur application en therapeutique
TW201718581A (zh) 2015-10-19 2017-06-01 英塞特公司 作為免疫調節劑之雜環化合物
LT3377488T (lt) 2015-11-19 2023-01-10 Incyte Corporation Heterocikliniai junginiai, kaip imunomoduliatoriai
SI3394033T1 (sl) 2015-12-22 2021-03-31 Incyte Corporation Heterociklične spojine kot imunomodulatorji
MA44860A (fr) 2016-05-06 2019-03-13 Incyte Holdings Corp Composés hétérocycliques utilisés comme immunomodulateurs
WO2017205464A1 (en) 2016-05-26 2017-11-30 Incyte Corporation Heterocyclic compounds as immunomodulators
EP4137489A1 (en) 2016-06-20 2023-02-22 Incyte Corporation Heterocyclic compounds as immunomodulators
WO2018013789A1 (en) 2016-07-14 2018-01-18 Incyte Corporation Heterocyclic compounds as immunomodulators
EP3504198B1 (en) 2016-08-29 2023-01-25 Incyte Corporation Heterocyclic compounds as immunomodulators
US20180179179A1 (en) 2016-12-22 2018-06-28 Incyte Corporation Heterocyclic compounds as immunomodulators
MX2019007416A (es) 2016-12-22 2019-12-11 Incyte Corp Derivados de benzooxazol como inmunomoduladores.
TWI798192B (zh) 2016-12-22 2023-04-11 美商英塞特公司 免疫調節劑化合物及使用方法
ES2874756T3 (es) 2016-12-22 2021-11-05 Incyte Corp Derivados de triazolo[1,5-A]piridina como inmunomoduladores
ES2940750T3 (es) 2018-03-30 2023-05-11 Incyte Corp Compuestos heterocíclicos como inmunomoduladores
HRP20230306T1 (hr) 2018-05-11 2023-05-12 Incyte Corporation Derivati tetrahidro-imidazo[4,5-c]piridina kao pd-l1 imunomodulatori
CA3150434A1 (en) 2019-08-09 2021-02-18 Incyte Corporation Salts of a pd-1/pd-l1 inhibitor
TW202126652A (zh) 2019-09-30 2021-07-16 美商英塞特公司 作為免疫調節劑之吡啶并［３，２—ｄ］嘧啶化合物
KR20220101664A (ko) 2019-11-11 2022-07-19 인사이트 코포레이션 Pd-1/pd-l1 억제제의 염 및 결정질 형태
US11760756B2 (en) 2020-11-06 2023-09-19 Incyte Corporation Crystalline form of a PD-1/PD-L1 inhibitor
US11866434B2 (en) 2020-11-06 2024-01-09 Incyte Corporation Process for making a PD-1/PD-L1 inhibitor and salts and crystalline forms thereof
WO2022099018A1 (en) 2020-11-06 2022-05-12 Incyte Corporation Process of preparing a pd-1/pd-l1 inhibitor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2903105A1 (fr) * 2006-07-03 2008-01-04 Sanofi Aventis Sa Derives de 2-benzoyl-imidazopyridines, leur preparation et leur application en therapeutique
FR2903107B1 (fr) * 2006-07-03 2008-08-22 Sanofi Aventis Sa Derives d'imidazopyridine-2-carboxamides, leur preparation et leur application en therapeutique
FR2903106B1 (fr) * 2006-07-03 2010-07-30 Sanofi Aventis Utilisations de 2-benzoyl-imidazopyridines en therapeutique
FR2906250B1 (fr) * 2006-09-22 2008-10-31 Sanofi Aventis Sa Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique
FR2928923B1 (fr) * 2008-03-21 2010-04-23 Sanofi Aventis Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques
FR2928922B1 (fr) * 2008-03-21 2010-04-23 Sanofi Aventis Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
FR2928921A1 (fr) 2009-09-25
ES2397931T3 (es) 2013-03-12
ME01098B (me) 2012-12-20
EA201071110A1 (ru) 2011-04-29
TW201000477A (en) 2010-01-01
EP2262803A1 (fr) 2010-12-22
WO2009144391A1 (fr) 2009-12-03
MX2010010259A (es) 2011-06-01
CY1113549T1 (el) 2016-06-22
DK2262803T3 (da) 2013-02-04
EA018266B1 (ru) 2013-06-28
FR2928921B1 (fr) 2010-04-23
HRP20130029T1 (hr) 2013-02-28
CN102036988B (zh) 2013-08-07
RS52652B (en) 2013-06-28
NZ588081A (en) 2012-07-27
SI2262803T1 (sl) 2013-02-28
US20110065699A1 (en) 2011-03-17
IL208248A0 (en) 2010-12-30
AU2009253231B2 (en) 2013-07-11
CN102036988A (zh) 2011-04-27
PT2262803E (pt) 2013-01-28
MA32246B1 (fr) 2011-04-01
KR20100129774A (ko) 2010-12-09
CO6300865A2 (es) 2011-07-21
UY31727A (es) 2009-11-10
EP2262803B1 (fr) 2012-10-17
CA2718953A1 (fr) 2009-12-03
PE20091818A1 (es) 2009-12-12
US8148370B2 (en) 2012-04-03
BRPI0908999A2 (pt) 2015-08-04
AU2009253231A1 (en) 2009-12-03
CA2718953C (fr) 2016-08-16
BRPI0908999A8 (pt) 2016-07-12
JP5508383B2 (ja) 2014-05-28
JP2011515380A (ja) 2011-05-19
AR070992A1 (es) 2010-05-19
CL2009000695A1 (es) 2010-08-13
PL2262803T3 (pl) 2013-03-29

Similar Documents

Publication Publication Date Title
PL2262803T3 (pl) Wielopodstawione pochodne 2-arylo-6-fenyloimidazo[1,2-A]pirydyn, ich wytwarzanie i ich zastosowanie w lecznictwie
ZA201006725B (en) Polysubstituted derivatives of 6-heteroaryl-imidazo[1,2-a]pyridines,and preparation and therapeutic use thereof
ZA201006726B (en) Polysubstituted derivatives of 2-heteroaryl-6-phenyl-imidazo[1,2-a] pyridines,and preparation and therapeutic use thereof
ZA201006728B (en) Polysubstituted 2-aryl-6-phenyl-imidazo[1,2-a]pyridine derivatives,and preparation and therapeutic use thereof
IL216609A0 (en) Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives
ZA201005201B (en) Azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof
IL207078A0 (en) Azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof
IL216226A0 (en) Cyclopenta [c] pyrrole-2-carboxylate derivatives, preparation thereof, and therapeutic use thereof
IL215286A0 (en) 9h-pyrrolo[2,3-b:5,4-c]dipridine azacarboline derivatives, preparation thereof, and therapeutic use thereof
IL206673A0 (en) Imidazo[1,2-a]pyridine-2-carboxamide derivatives, their preparation and their therapeutic application
HK1163679A1 (en) Derivatives of 2-pyridin-2-yl-pyrazol-3(2h)-one, preparation and therapeutic use thereof 2--2---3(2h)-
HK1158632A1 (en) Derivatives of 2-oxo-alkyl-1-piperazin-2-one, preparation method thereof and therapeutic use of same 2--1--2-
ZA201004643B (en) Derivatives of n-heterocyclic-imidazo[1,2-a]pyridine-2-carboxamides,preparation thereof and therapeutic application thereof
ZA201004644B (en) "derivatives of 6-heterocyclic-imidazo[1,2-a]pyrroine-2-carboxamides,preparation thereof and therapeutic application thereof"
ZA201000745B (en) Tricyclic n-heteroaryl-carboxamide derivatives,preparation thereof and therapeutic use of same
SI2106401T1 (sl) Derivati pirolopiridin karboksamidov njihova priprava in njihova terapevtska uporaba
ZA201004641B (en) Derivatives of n-phenyl-imidazo[1,2-a]pyridine-2-carboxamides,preparation thereof and therapeutic application thereof
ZA201100251B (en) Substituted 1-benzyl-cinnolin-4(1h)-one derivatives,preparation thereof,and therapeutic use thereof
IL215512A0 (en) Substituted 1-alkylcinnolin-4(1h)-one derivatives, preparation thereof and therapeutic application of same
SI2477990T1 (sl) 5-fenil-pirazolopiridinski derivati, njihova priprava in terapevtska uporaba
ZA201004646B (en) Derivatives of n-heterocyclic-6-heterocyclic-imidazo[1,2-a]pyridine-2-carboxamides,preparation thereof and therapeutic application thereof
IL206667A0 (en) 2-HETEROAROYLIMIDAZO[1,2-a]PYRIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
IL206665A0 (en) 2-BENZOYLIMIDAZO[1,2-a]PYRIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF
IL213580A0 (en) Derivatives of 6-cycloamino-2,3-di-pyridinyl-imidazo[1,2-b]-pyridazine, preparation and therapeutic application thereof