MD734Z - Method for treating chronic marginal periodontitis - Google Patents
Method for treating chronic marginal periodontitis Download PDFInfo
- Publication number
- MD734Z MD734Z MDS20130126A MDS20130126A MD734Z MD 734 Z MD734 Z MD 734Z MD S20130126 A MDS20130126 A MD S20130126A MD S20130126 A MDS20130126 A MD S20130126A MD 734 Z MD734 Z MD 734Z
- Authority
- MD
- Moldova
- Prior art keywords
- treatment
- periodontitis
- treating chronic
- marginal periodontitis
- periodontal
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 18
- 201000001245 periodontitis Diseases 0.000 title claims abstract description 16
- 230000001684 chronic effect Effects 0.000 title claims abstract description 9
- 208000005888 Periodontal Pocket Diseases 0.000 claims abstract description 12
- 229950003937 tolonium Drugs 0.000 claims abstract description 5
- HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 claims abstract description 5
- 230000001678 irradiating effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 6
- 230000006378 damage Effects 0.000 description 6
- 239000003504 photosensitizing agent Substances 0.000 description 6
- 244000005700 microbiome Species 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 230000003239 periodontal effect Effects 0.000 description 4
- 230000000813 microbial effect Effects 0.000 description 3
- 238000002428 photodynamic therapy Methods 0.000 description 3
- 238000005498 polishing Methods 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 208000001277 chronic periodontitis Diseases 0.000 description 2
- 230000001472 cytotoxic effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000005713 exacerbation Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 244000000010 microbial pathogen Species 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000006386 Bone Resorption Diseases 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010033372 Pain and discomfort Diseases 0.000 description 1
- 208000009596 Tooth Mobility Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 230000024279 bone resorption Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 231100000433 cytotoxic Toxicity 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 230000003505 mutagenic effect Effects 0.000 description 1
- 210000004053 periapical tissue Anatomy 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000002186 photoactivation Effects 0.000 description 1
- 238000006552 photochemical reaction Methods 0.000 description 1
- 230000002165 photosensitisation Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000003144 traumatizing effect Effects 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
Landscapes
- Dental Preparations (AREA)
Abstract
Description
Invenţia se referă la medicină, şi anume la stomatologie, şi poate fi aplicată pentru tratamentul parodontitei marginale cronice. The invention relates to medicine, namely to dentistry, and can be applied for the treatment of chronic marginal periodontitis.
Este cunoscută metoda de tratament al parodontitei marginale cronice, care constă în prelucrarea supra- şi subgingivală cu ultrasunet şi poleirea suprafeţelor dentare, sanarea şi chiuretajul pungilor parodontale şi efectuarea terapiei fotodinamice cu aplicarea gelului Fotoditazină de 1% pe suprafeţele inflamate ale mucoasei orale şi în pungile parodontale pentru 8…10 min, după lavajul pungilor parodontale se iradiază suprafeţele afectate cu un fascicul de laser LED cu lungimea de undă de 660±5 nm, puterea iradierii de 0,2 W, cu expoziţia de 1…2 min, durata totală a procedurii este de 20…30 min, după care este efectuată o cură de reflexoterapie timp de 15…20 min în decurs de 10 zile [1]. The method of treatment of chronic marginal periodontitis is known, which consists of supra- and subgingival ultrasound processing and polishing of dental surfaces, sanitation and curettage of periodontal pockets and performing photodynamic therapy with the application of 1% Photoditazine gel on the inflamed surfaces of the oral mucosa and in the periodontal pockets for 8…10 min, after the periodontal pockets are washed, the affected surfaces are irradiated with an LED laser beam with a wavelength of 660±5 nm, irradiation power of 0.2 W, with exposure of 1…2 min, the total duration of the procedure is 20…30 min, after which a reflexology course is performed for 15…20 min within 10 days [1].
Însă, această metodă presupune efectuarea terapiei fotodinamice cu iradierea cu un fascicul laser LED cu putere mică, ce nu asigură distrugerea tuturor microorganismelor din pungile parodontale, în special a celor care se află în profunzime, fapt care poate cauza extinderea inflamaţiei şi cronicizarea procesului. Prin urmare, metoda dată nu este eficientă în tratamentul formelor cronice, agresive de parodontită marginală, este dificilă în aplicare, necesită mult timp pentru realizare, din care cauză provoacă disconfortul pacientului în timpul tratamentului. However, this method involves performing photodynamic therapy with irradiation with a low-power LED laser beam, which does not ensure the destruction of all microorganisms in periodontal pockets, especially those located deep inside, which can cause the spread of inflammation and the chronicization of the process. Therefore, this method is not effective in the treatment of chronic, aggressive forms of marginal periodontitis, is difficult to implement, requires a lot of time to perform, which is why it causes discomfort to the patient during treatment.
Problema pe care o rezolvă prezenta invenţie este sporirea eficienţei tratamentului parodontitelor, majorarea efectului bactericid şi a duratei perioadei de remisie şi prevenirea acutizărilor, complicaţiilor, reducerea durerii şi a disconfortului pacientului în timpul tratamentului. The problem solved by the present invention is to increase the efficiency of periodontitis treatment, increase the bactericidal effect and the duration of the remission period and prevent exacerbations, complications, reduce the patient's pain and discomfort during treatment.
Esenţa invenţiei constă în aceea că după prelucrarea supra- şi subgingivală cu ultrasunet şi poleirea suprafeţelor dentare, se efectuează sanarea şi chiuretajul pungilor parodontale, apoi în ele se aplică albastru de toluidină sub formă de gel cu concentraţia de 0,1 mg/ml, timp de 1…2 min, ulterior se iradiază cu lumină LED cu lungimea de undă de 625…635 nm, puterea de 2,0…3,0 W, timp de 40…60 s, seria de tratament constituie 1…4 şedinţe. The essence of the invention is that after supra- and subgingival ultrasonic processing and polishing of the dental surfaces, the periodontal pockets are cleaned and cured, then toluidine blue is applied in the form of a gel with a concentration of 0.1 mg/ml for 1…2 min, then irradiated with LED light with a wavelength of 625…635 nm, power of 2.0…3.0 W, for 40…60 s, the treatment series consists of 1…4 sessions.
Metoda propusă asigură dezinfectarea eficientă a pungilor parodontale, fapt care stopează propagarea infecţiei în profunzimea lor şi resorbţia ulterioară a ţesutului osos, previne apariţia retracţiei gingivale şi a mobilităţii dinţilor, ceea ce exclude extracţia ulterioară a lor. The proposed method ensures effective disinfection of periodontal pockets, which stops the spread of infection in their depth and subsequent resorption of bone tissue, prevents the occurrence of gingival retraction and tooth mobility, which excludes their subsequent extraction.
Gelul de albastru de toluidină cu viscozitate medie, utilizat în calitate de fotosensibilizator, se introduce cu uşurinţă în punga parodontală şi pătrunde în profunzimea ei, nu se prelinge pe gingie, este inofensiv pentru ţesuturile periapicale, prin urmare se previne eventualitatea de iritare a acestei zone. Fotosensibilizatorul are capacitatea de a penetra rapid membrana celulară a microorganismelor, astfel perioada de timp necesară pentru a-l lega în mod eficient cu celulele microbiene constituie maximum 1…2 min, fapt care permite reducerea duratei şedinţei de tratament. Iradierea cu lumină LED se efectuează cu lungimea de undă corespunzătoare absorbţiei maxime a fotosensibilizatorului de 625…635 nm şi o densitate de putere suficientă pentru activarea lui. În urma iradierii se declanşează reacţii fotochimice, având ca rezultat formarea de oxigen atomic şi de radicali liberi, care induc distrugerea microorganismelor amplasate în profunzimea pungilor parodontale. Puterea de 2,0…3,0 W a iradierii LED asigură producerea unui efect bactericid momentan. Ghidul optic, având forma care repetă configuraţia pungii parodontale, asigură propagarea luminii pe întreaga lungime a lui, în mod uniform la o distanţă de 5 mm de la suprafaţa ghidului, astfel se efectuează o iradiere efectivă a zonei afectate, fără a o trauma. Dispozitivul dat produce vibraţii care majorează gradul de contactare a fotosensibilizatorului cu ghidul optic şi optimizează difuzia fotosensibilizatorului în microcanalele radiculare, în aşa mod asigurându-se înlăturarea mai rapidă a microorganismelor şi prevenindu-se formarea bulelor de aer. The medium-viscosity toluidine blue gel, used as a photosensitizer, is easily introduced into the periodontal pocket and penetrates its depth, does not drip onto the gum, is harmless to periapical tissues, therefore, the possibility of irritation of this area is prevented. The photosensitizer has the ability to quickly penetrate the cell membrane of microorganisms, so the time period required to effectively bind it with microbial cells is a maximum of 1…2 min, which allows reducing the duration of the treatment session. Irradiation with LED light is performed with a wavelength corresponding to the maximum absorption of the photosensitizer of 625…635 nm and a power density sufficient for its activation. Following irradiation, photochemical reactions are triggered, resulting in the formation of atomic oxygen and free radicals, which induce the destruction of microorganisms located in the depths of the periodontal pockets. The power of 2.0…3.0 W of LED irradiation ensures the production of a momentary bactericidal effect. The optical guide, having a shape that repeats the configuration of the periodontal pocket, ensures the propagation of light along its entire length, uniformly at a distance of 5 mm from the surface of the guide, thus providing effective irradiation of the affected area, without traumatizing it. This device produces vibrations that increase the degree of contact of the photosensitizer with the optical guide and optimize the diffusion of the photosensitizer in the root microchannels, thus ensuring faster removal of microorganisms and preventing the formation of air bubbles.
Zona efectului citotoxic al oxigenului singlet nu depăşeşte 0,02 µm, iar durata de acţiune în sistemele biologice este mai mică de 0,04 ms, prin urmare este exclusă eventualitatea distrugerii ţesuturilor parodonţiului. The cytotoxic effect zone of singlet oxygen does not exceed 0.02 µm, and the duration of action in biological systems is less than 0.04 ms, therefore the possibility of destruction of periodontal tissues is excluded.
Metoda dată exclude necesitatea aplicării antibioticelor, astfel se evită eventualitatea dezvoltării rezistenţei microorganismelor la tratamentul aplicat, eficienţa metodei nu este influenţată de sensibilitatea microorganismelor patogene la preparatele antibacteriene, sunt distruse tulpinile microbiene antibiorezistente şi cele persistente în formă de biofilme bacteriene. Eliminarea bacteriilor are loc foarte rapid, în câteva minute sau chiar secunde. Terapia fotodinamică are un spectru larg de acţiune asupra tuturor agenţilor patogeni microbieni, efectul antibacterian nu se reduce în timp, în cazul aplicării şedinţelor repetate. Substanţa de fotosensibilizare nu exercită acţiune citotoxică fără fotoactivare, nu exercită acţiune mutagenă, fapt care exclude probabilitatea selectării tulpinilor microbiene rezistente. Acţiunea bactericidă are un caracter local, nu exercită efect nociv asupra florei saprofite a întregului organism, nu provoacă reacţii alergice de tip lent sau imediat. This method eliminates the need for antibiotics, thus avoiding the possibility of developing resistance of microorganisms to the applied treatment, the effectiveness of the method is not influenced by the sensitivity of pathogenic microorganisms to antibacterial preparations, antibiotic-resistant microbial strains and those persistent in the form of bacterial biofilms are destroyed. The elimination of bacteria occurs very quickly, within a few minutes or even seconds. Photodynamic therapy has a broad spectrum of action on all microbial pathogens, the antibacterial effect does not decrease over time, in the case of repeated sessions. The photosensitizing substance does not exert cytotoxic action without photoactivation, does not exert mutagenic action, which excludes the likelihood of selecting resistant microbial strains. The bactericidal action is local in nature, does not exert a harmful effect on the saprophytic flora of the whole organism, does not cause allergic reactions of a slow or immediate type.
Prin urmare, eficacitatea înaltă a metodei propuse asigură prevenirea acutizărilor şi a complicaţiilor parodontitelor marginale. Metoda revendicată este simplă şi rapidă în aplicare, nu provoacă lezarea ţesuturilor cavităţii orale, durere sau discomfort pacientului în timpul tratamentului. Therefore, the high effectiveness of the proposed method ensures the prevention of exacerbations and complications of marginal periodontitis. The claimed method is simple and quick to implement, does not cause damage to the tissues of the oral cavity, pain or discomfort to the patient during treatment.
Rezultatul tehnic constă în sporirea eficacităţii tratamentului parodontitelor marginale cronice, majorarea efectului bactericid, ameliorarea rapidă a stării locale cu diminuarea simptomelor de afectare a ţesuturilor parodonţiului, reducerea semnificativă a duratei tratamentului, regenerarea rapidă, reducerea frecvenţei recidivelor, prevenirea apariţiei complicaţiilor, reducerea rapidă a durerii, disconfortului şi ameliorarea calităţii vieţii pacientului. The technical result consists in increasing the effectiveness of the treatment of chronic marginal periodontitis, increasing the bactericidal effect, rapid improvement of the local condition with a decrease in the symptoms of damage to periodontal tissues, significant reduction in the duration of treatment, rapid regeneration, reduction in the frequency of relapses, prevention of complications, rapid reduction of pain, discomfort and improvement of the patient's quality of life.
Metoda de tratament al parodontitelor marginale cronice se realizează în modul următor: după prelucrarea supra- şi subgingivală cu ultrasunet şi poleirea suprafeţelor dentare, se efectuează sanarea şi chiuretajul pungilor parodontale, apoi în ele se aplică albastru de toluidină sub formă de gel cu concentraţia de 0,1 mg/ml, timp de 1…2 min, ulterior se iradiază cu lumină LED cu lungimea de undă de 625…635 nm, puterea de 2,0…3,0 W, timp de 40…60 s, seria de tratament constituie 1…4 şedinţe în funcţie de gravitatea parodontitei. The treatment method for chronic marginal periodontitis is carried out as follows: after supra- and subgingival ultrasound processing and polishing of the tooth surfaces, the periodontal pockets are cleaned and cured, then toluidine blue is applied in the form of a gel with a concentration of 0.1 mg/ml for 1…2 min, then irradiated with LED light with a wavelength of 625…635 nm, power of 2.0…3.0 W, for 40…60 s, the treatment series consists of 1…4 sessions depending on the severity of periodontitis.
Exemplul 1 Example 1
Pacientul A., 38 ani. Diagnosticul: parodontită cronică generalizată, formă gravă. Tratamentul parodontitei a fost efectuat după metoda descrisă, s-au aplicat 4 şedinţe de tratament. Pacientul a suportat bine şedinţele curative, fără a manifesta semne de disconfort. După 1 an de la efectuarea tratamentului, semne de progresare a leziunilor ţesuturilor parodonţiului şi a resorbţiei osoase nu s-au depistat. Patient A., 38 years old. Diagnosis: generalized chronic periodontitis, severe form. Treatment of periodontitis was carried out according to the described method, 4 treatment sessions were applied. The patient tolerated the curative sessions well, without showing signs of discomfort. After 1 year of treatment, signs of progression of periodontal tissue lesions and bone resorption were not detected.
Exemplul 2 Example 2
Pacienta M., 16 ani. Diagnosticul: parodontită cronică generalizată, formă medie. Tratamentul parodontitei a fost efectuat după metoda descrisă. Pacienta a suportat bine şedinţa de tratament. După 8 luni de la efectuarea tratamentului, semne de inflamaţie sau de distrucţie a ţesuturilor parodonţiului nu s-au depistat. Patient M., 16 years old. Diagnosis: generalized chronic periodontitis, moderate form. Treatment of periodontitis was performed according to the described method. The patient tolerated the treatment session well. After 8 months of treatment, no signs of inflammation or destruction of periodontal tissues were detected.
Metoda propusă a fost aplicată pentru tratamentul parodontitelor marginale cronice la 38 de pacienţi în cadrul Catedrei Chirurgie O.M.F. Pediatrică, Pedodonţie şi Ortodonţie a USMF ”Nicolae Testemiţanu”. Rezultatele sunt pozitive, în perioada de observaţie de la 1 până la 2 ani nu s-au înregistrat complicaţii şi efecte secundare. The proposed method was applied for the treatment of chronic marginal periodontitis in 38 patients within the Department of Pediatric O.M.F. Surgery, Pedodontics and Orthodontics of the "Nicolae Testemiţanu" University of Medicine and Pharmacy. The results are positive, during the observation period of 1 to 2 years no complications and side effects were recorded.
1. RU 2460491 C2 2012.09.10 1. RU 2460491 C2 2012.09.10
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20130126A MD734Z (en) | 2013-07-12 | 2013-07-12 | Method for treating chronic marginal periodontitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20130126A MD734Z (en) | 2013-07-12 | 2013-07-12 | Method for treating chronic marginal periodontitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD734Y MD734Y (en) | 2014-02-28 |
| MD734Z true MD734Z (en) | 2014-09-30 |
Family
ID=50231654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20130126A MD734Z (en) | 2013-07-12 | 2013-07-12 | Method for treating chronic marginal periodontitis |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD734Z (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD916G2 (en) * | 1996-12-09 | 1998-12-31 | Институтул Национал Де Фармачие | Ungent for stomatologic deseases treatment |
| MD3904G2 (en) * | 2008-05-07 | 2009-12-31 | Валериу ФАЛА | Composition for biosoluble medicated film for treatment of parodentium affections and of lesions of tunica mucosa of mouth (variants) |
| MD3905G2 (en) * | 2008-05-07 | 2010-01-31 | Валериу ФАЛА | Remedy of durable action in the form of gel for treatment of parodentium affections (variants) |
| MD3938G2 (en) * | 2008-05-07 | 2010-02-28 | Валериу ФАЛА | Method for treating the migratory periodontitis |
| MD424Z (en) * | 2010-09-06 | 2012-05-31 | Валериу ФАЛА | Method for treatment of periodontium diseases |
| RU2460491C2 (en) * | 2010-08-30 | 2012-09-10 | Альберт Анатольевич Лютиков | Method of treating chronic periodontitis |
| MD569Z (en) * | 2011-03-29 | 2013-07-31 | Дорин ИСТРАТИ | Method of regenerating the roots of immature permanent teeth in children |
| MD582Z (en) * | 2012-07-09 | 2013-08-31 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Method for preventing the dental caries in children with intellectual disabilities |
| MD597Z (en) * | 2012-08-16 | 2013-09-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Method for treating the dental caries in children with intellectual disabilities |
-
2013
- 2013-07-12 MD MDS20130126A patent/MD734Z/en not_active IP Right Cessation
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MD916G2 (en) * | 1996-12-09 | 1998-12-31 | Институтул Национал Де Фармачие | Ungent for stomatologic deseases treatment |
| MD3904G2 (en) * | 2008-05-07 | 2009-12-31 | Валериу ФАЛА | Composition for biosoluble medicated film for treatment of parodentium affections and of lesions of tunica mucosa of mouth (variants) |
| MD3905G2 (en) * | 2008-05-07 | 2010-01-31 | Валериу ФАЛА | Remedy of durable action in the form of gel for treatment of parodentium affections (variants) |
| MD3938G2 (en) * | 2008-05-07 | 2010-02-28 | Валериу ФАЛА | Method for treating the migratory periodontitis |
| RU2460491C2 (en) * | 2010-08-30 | 2012-09-10 | Альберт Анатольевич Лютиков | Method of treating chronic periodontitis |
| MD424Z (en) * | 2010-09-06 | 2012-05-31 | Валериу ФАЛА | Method for treatment of periodontium diseases |
| MD569Z (en) * | 2011-03-29 | 2013-07-31 | Дорин ИСТРАТИ | Method of regenerating the roots of immature permanent teeth in children |
| MD582Z (en) * | 2012-07-09 | 2013-08-31 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Method for preventing the dental caries in children with intellectual disabilities |
| MD597Z (en) * | 2012-08-16 | 2013-09-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Method for treating the dental caries in children with intellectual disabilities |
Also Published As
| Publication number | Publication date |
|---|---|
| MD734Y (en) | 2014-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Karimi et al. | Efficacy of antimicrobial photodynamic therapy as an adjunctive to mechanical debridement in the treatment of peri-implant diseases: a randomized controlled clinical trial | |
| Caccianiga et al. | Clinical, radiographic and microbiological evaluation of high level laser therapy, a new photodynamic therapy protocol, in peri‐implantitis treatment; a pilot experience | |
| Maver-Biscanin et al. | Effect of low-level laser therapy on Candida albicans growth in patients with denture stomatitis | |
| Bal et al. | Effects of photodynamic therapy with indocyanine green on Streptococcus mutans biofilm | |
| Derikvand et al. | Antimicrobial Photodynamic Therapy with Diode laser and Methylene blue as an adjunct to scaling and root planning: A clinical trial | |
| Tokuc et al. | Bactericidal effect of 2780 nm Er, Cr: YSGG laser combined with 940 nm diode laser in Enterococcus faecalis elimination: a comparative study | |
| Gutknecht | Lasers in endodontics | |
| RU2460491C2 (en) | Method of treating chronic periodontitis | |
| Shibli | Is laser the best choice for the treatment of peri-implantitis | |
| RU2235568C1 (en) | Method for treating chronic tonsillitis | |
| Almoharib | Erbium-doped yttrium aluminium garnet (Er: YAG) lasers in the treatment of peri-implantitis | |
| RU2379073C2 (en) | Method of laser treatment of chronic tonsillitis with using photosensitiser | |
| Asnaashari et al. | Clinical application of 810nm diode laser and low level laser therapy for treating an endodontic problem a case presentation | |
| MD734Z (en) | Method for treating chronic marginal periodontitis | |
| RU2696228C1 (en) | Method for complex therapy of periodontium diseases by laser microsurgery and singlet phototherapy | |
| RU2522211C1 (en) | Method of treating periodontitis | |
| RU2543031C1 (en) | Method of treating radicular cysts | |
| RU2248785C1 (en) | Method for treating the cases of chronic generalized periodontitis of mild and moderate severity degree | |
| Stănuşi et al. | Endodontic bacterial reduction using Diode LASER radiation–short literature review | |
| RU2652565C1 (en) | Method for treating odontogenic diseases using laser photodynamic singlet oxytherapy | |
| RU2556971C1 (en) | Method of deep caries treatment | |
| RU2753794C1 (en) | Method for the treatment of chronic periodontitis using the technology of transcanal laser non-pigment photoablation | |
| RU2491031C1 (en) | Method of treating complicated intra-canal perforations of solid dental tissues | |
| RU2852466C1 (en) | Method for preventing peri-implantitis in maxillofacial surgery | |
| Al-Jaberi et al. | In vitro evaluation of photodynamic disinfection and conventional root canal irriga-tion protocol. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG9Y | Short term patent issued | ||
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) |