MD4209B1 - Procedeu de obtinere a sclareoloxidului - Google Patents
Procedeu de obtinere a sclareoloxidului Download PDFInfo
- Publication number
- MD4209B1 MD4209B1 MDA20120036A MD20120036A MD4209B1 MD 4209 B1 MD4209 B1 MD 4209B1 MD A20120036 A MDA20120036 A MD A20120036A MD 20120036 A MD20120036 A MD 20120036A MD 4209 B1 MD4209 B1 MD 4209B1
- Authority
- MD
- Moldova
- Prior art keywords
- sclareoloxide
- sclareol
- extraction
- producing
- catalyst
- Prior art date
Links
- LAEIZWJAQRGPDA-CIRFHOKZSA-N (4ar,6as,10as,10br)-3,4a,7,7,10a-pentamethyl-1,5,6,6a,8,9,10,10b-octahydrobenzo[f]chromene Chemical compound CC1(C)CCC[C@]2(C)[C@H]3CC=C(C)O[C@]3(C)CC[C@H]21 LAEIZWJAQRGPDA-CIRFHOKZSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- XVULBTBTFGYVRC-HHUCQEJWSA-N sclareol Chemical compound CC1(C)CCC[C@]2(C)[C@@H](CC[C@](O)(C)C=C)[C@](C)(O)CC[C@H]21 XVULBTBTFGYVRC-HHUCQEJWSA-N 0.000 abstract 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- XVULBTBTFGYVRC-UHFFFAOYSA-N Episclareol Natural products CC1(C)CCCC2(C)C(CCC(O)(C)C=C)C(C)(O)CCC21 XVULBTBTFGYVRC-UHFFFAOYSA-N 0.000 abstract 2
- LAEIZWJAQRGPDA-UHFFFAOYSA-N Manoyloxid Natural products CC1(C)CCCC2(C)C3CC=C(C)OC3(C)CCC21 LAEIZWJAQRGPDA-UHFFFAOYSA-N 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- 238000000605 extraction Methods 0.000 abstract 2
- 239000000047 product Substances 0.000 abstract 2
- 244000182022 Salvia sclarea Species 0.000 abstract 1
- 235000002911 Salvia sclarea Nutrition 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 238000005899 aromatization reaction Methods 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004821 distillation Methods 0.000 abstract 1
- 150000004141 diterpene derivatives Chemical class 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 230000008020 evaporation Effects 0.000 abstract 1
- 239000003205 fragrance Substances 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 238000010525 oxidative degradation reaction Methods 0.000 abstract 1
- 238000005949 ozonolysis reaction Methods 0.000 abstract 1
- OVARTBFNCCXQKS-UHFFFAOYSA-N propan-2-one;hydrate Chemical compound O.CC(C)=O OVARTBFNCCXQKS-UHFFFAOYSA-N 0.000 abstract 1
- 238000011403 purification operation Methods 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 235000002020 sage Nutrition 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000011877 solvent mixture Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
- 239000000341 volatile oil Substances 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Inventia se refera la un procedeu de obtinere a sclareoloxidului (1) - compus utilizat în calitate de ingredient al diferitor compozitii de aromatizare, precum si ca intermediar în sinteza altor produse odorante valoroase cu structura terpenica.În calitate de materie prima este folosit sclareolul (2) - un compus diterpenic labdanic usor disponibil din deseurile producerii uleiului eteric de salvie (Salvia sclarea L.).Procedeul include o singura operatie de scindare oxidativa a catenei laterale a sclareolului prin tratare cu ozon în prezenta unui co-oxidant catalitic - diacetat de plumb, într-un amestec omogen de acetona-apa la temperatura de -20°C...+15°C. Izolarea produsului de reactie include distilarea acetonei, extractia suspensiei obtinute cu un solvent organic potrivit si eliminarea lui ulterioara prin distilare la presiune redusa. Produsii de transformare a catalizatorului pot fi usor izolati din faza apoasa ramasa de la extractie, care pot fi mai apoi usor reciclati.Sclareoloxidul brut, astfel obtinut, are o puritate de cel putin 97% si poate fi utilizat fara o purificare suplimentara.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20120036A MD4209C1 (ro) | 2012-03-30 | 2012-03-30 | Procedeu de obţinere a sclareoloxidului |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20120036A MD4209C1 (ro) | 2012-03-30 | 2012-03-30 | Procedeu de obţinere a sclareoloxidului |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD4209B1 true MD4209B1 (ro) | 2013-03-31 |
| MD4209C1 MD4209C1 (ro) | 2013-10-31 |
Family
ID=48045141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20120036A MD4209C1 (ro) | 2012-03-30 | 2012-03-30 | Procedeu de obţinere a sclareoloxidului |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD4209C1 (ro) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB589650A (ro) * | 1947-12-29 | 1947-06-26 | ||
| DE3942358A1 (de) * | 1989-12-21 | 1991-06-27 | Henkel Kgaa | Verfahren zur herstellung von sclareolid |
| MD217C2 (ro) * | 1992-07-15 | 1995-08-31 | Институт Химии Академии Наук Молдовы | Compoziţie pentru aromatizarea tutunului de fumat |
| EP0822191B1 (en) * | 1996-08-02 | 2001-09-19 | Quest International B.V. | Preparation of intermediates for norlabdane oxide |
| DE69706786T2 (de) * | 1996-08-02 | 2002-05-23 | Quest International B.V., Naarden | Herstellung von Norlabdan-Oxid-Zwischenprodukten |
| EP1171433B1 (en) * | 1999-04-16 | 2004-03-17 | Quest International B.V. | Preparation of norlabdane oxide |
| MD2349C2 (ro) * | 2003-02-03 | 2004-07-31 | "Тутун-Стс" С.А. | Compoziţie de aromatizare a amestecului de tutun şi procedeu de obţinere a amestecului de tutun aromatizat |
| MD2253C2 (ro) * | 2003-02-03 | 2004-03-31 | "Тутун-Стс" С.А. | Produs aromatizant pentru tutun de fumat, procedeu de obţinere a lui, compoziţie aromatică (variante), procedeu de obţinere a compoziţiei pentru produsele de tutunărie (variante) |
| DE102005015590A1 (de) * | 2005-04-05 | 2006-10-12 | Symrise Gmbh & Co. Kg | Verfahren zur Darstellung von Ketonen durch Ozonolyse |
| DE102005046535A1 (de) * | 2005-09-28 | 2007-03-29 | Symrise Gmbh & Co. Kg | Darstellung von Aldehyden durch Ozonolyse sekundärer Allylalkohole |
-
2012
- 2012-03-30 MD MDA20120036A patent/MD4209C1/ro not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MD4209C1 (ro) | 2013-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
| MM4A | Patent for invention definitely lapsed due to non-payment of fees |