MD4127C1 - Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus - Google Patents

Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus

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Publication number
MD4127C1
MD4127C1 MDA20100109A MD20100109A MD4127C1 MD 4127 C1 MD4127 C1 MD 4127C1 MD A20100109 A MDA20100109 A MD A20100109A MD 20100109 A MD20100109 A MD 20100109A MD 4127 C1 MD4127 C1 MD 4127C1
Authority
MD
Moldova
Prior art keywords
copper
substance
staphylococcus aureus
activity against
antimicrobial activity
Prior art date
Application number
MDA20100109A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD4127B1 (en
Inventor
Aurelian Gulea
Carolina Lozan-Tirşu
Victor Ţapcov
Original Assignee
Государственный Университет Молд0
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Государственный Университет Молд0 filed Critical Государственный Университет Молд0
Priority to MDA20100109A priority Critical patent/MD4127C1/en
Publication of MD4127B1 publication Critical patent/MD4127B1/en
Publication of MD4127C1 publication Critical patent/MD4127C1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

The invention relates to chemistry and medicine, namely to a biologically active coordination compound of copper from the class of thiosemicarbazonates of transition metals, which can be used as substance with antimicrobial activity against Staphylococcus aureus.Summary of the invention consists in the use as substance with antimicrobial activity against Staphylococcus aureus of di(µ-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} with the formula:
MDA20100109A 2010-10-06 2010-10-06 Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus MD4127C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20100109A MD4127C1 (en) 2010-10-06 2010-10-06 Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20100109A MD4127C1 (en) 2010-10-06 2010-10-06 Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus

Publications (2)

Publication Number Publication Date
MD4127B1 MD4127B1 (en) 2011-09-30
MD4127C1 true MD4127C1 (en) 2012-04-30

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MDA20100109A MD4127C1 (en) 2010-10-06 2010-10-06 Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus

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MD (1) MD4127C1 (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4174C1 (en) * 2011-10-25 2013-01-31 Институт Химии Академии Наук Молдовы Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties
MD4255C1 (en) * 2012-11-05 2014-05-31 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Tetraisothiocyanatocobaltate of bis(nicotinoylhydrazone)-2,6-diformil-4-methylphenol(methanol)(aqua)cobalt(II) and process for cultivation of microalga Porphyridium cruentum with the use thereof
MD4254C1 (en) * 2012-11-05 2014-05-31 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Hexafluorotitanate-bis[(dimethylglyoximato)-di-(thiocarbamide)cobalt(III)] dihydrate and process for cultivation of microalga Porphyridium cruentum with the use thereof
MD4253C1 (en) * 2012-11-05 2014-05-31 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Sulphato-bis(nicotinoylhydrazone)-2,6-diacetylpyridin-cobalt(II )monomethanol trihydrate and process for cultivation of microalga Porphyridium cruentum with the use thereof
MD4327C1 (en) * 2013-10-22 2015-09-30 Институт Химии Академии Наук Молдовы N-(D8,13-Bicyclohomofarnesenoyl)-3-amino-1,2,4-triazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4326C1 (en) * 2013-10-22 2015-09-30 Институт Химии Академии Наук Молдовы N-(D8,13-Bicyclohomofarnesenoylamino)carbazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4356C1 (en) * 2014-07-09 2016-02-29 Институт Химии Академии Наук Молдовы Bis[N'-(2-hydroxy-kO-benzylidene)pyridine-4-carbohydrazidate(-1)-k2N',O]iron(III) nitrate - water (2/3) and process for cultivation of microalga Porphyridium cruentum with its use
MD4366C1 (en) * 2014-07-09 2016-03-31 Институт Химии Академии Наук Молдовы Bis[1-phenyl-3-methyl-6-(pyridinium-4-il)-4,5-diaza-hexa-1,3,5-triene-1-hydroxy-6-olato-O1,N4,O6]iron(II)sulphate tetrahydrate and process for cultivation of microalga Porphyridium cruentum with its use
MD4365C1 (en) * 2014-07-09 2016-03-31 Институт Химии Академии Наук Молдовы Bis[1-phenyl-3-methyl-6-(pyridinium-4-yl)-4,5-diaza-hexa-1,3,5-triene-1,6-diolato-O1,N4,O6]iron(III) nitrate and process for cultivation of microalga Porphyridium cruentum with its use
MD4367C1 (en) * 2014-07-09 2016-03-31 Институт Химии Академии Наук Молдовы Bis[N'-(2-hydroxy-kO-3-carboxybenzilidene)pyridine-3-carbohydrazidate(-1)-k2N',O]iron(III) perchlorate - water (4/5) and process for cultivation of microalga Porphyridium cruentum with its use

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4383C1 (en) * 2015-03-06 2016-06-30 Государственный Университет Молд0 Acetato-(8-formylquinolinethiosemicarbazono)copper(II) compound, exhibiting antibacterial activity

Citations (9)

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Publication number Priority date Publication date Assignee Title
WO1985000955A1 (en) * 1983-08-22 1985-03-14 A/S Cheminova A biocidal, particularly fungicidal and/or bactericidal composition and thiosemicarbazones and metal complexes thereof for use in the composition
US4657903A (en) * 1982-03-31 1987-04-14 The United States Of America As Represented By The Secretary Of The Army Transition metal complexes of the selenium analogs of 2-acetyl- and 2-propionylpyridine thiosemicarbazones useful for treating malarial infections and leukemia
MD195C2 (en) * 1994-12-05 1995-11-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова The copper complexes with antistaphylococcus properties
MD1650G2 (en) * 1999-12-06 2001-11-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова 3,5-Dibromsalicylidenethiosemicarbazidopyridinecopper possessing antistaphylococcia and antistreptococcia activity
MD1812C2 (en) * 2000-12-29 2002-06-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Copper complexes as bacteria and fungi inhibitors
MD2003C2 (en) * 2001-01-10 2003-03-31 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Copper chelate compounds (II) with antimicrobial and antimycotic activity
MD2942C2 (en) * 2004-04-27 2006-06-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Di(µ-O)-bis(3,5-dibromosalicylidene thiosemicarbazonatocopper)
MD3032G2 (en) * 2005-10-31 2006-11-30 Государственный Университет Молд0 Sulfanilamide-containing naphthalidenethiosemicarbazidates of copper(II)
MD3124C2 (en) * 2005-05-25 2007-03-31 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Sulfanilamide-containing salicylidenethiosemicarbazidates of copper(II)

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657903A (en) * 1982-03-31 1987-04-14 The United States Of America As Represented By The Secretary Of The Army Transition metal complexes of the selenium analogs of 2-acetyl- and 2-propionylpyridine thiosemicarbazones useful for treating malarial infections and leukemia
WO1985000955A1 (en) * 1983-08-22 1985-03-14 A/S Cheminova A biocidal, particularly fungicidal and/or bactericidal composition and thiosemicarbazones and metal complexes thereof for use in the composition
MD195C2 (en) * 1994-12-05 1995-11-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова The copper complexes with antistaphylococcus properties
MD1650G2 (en) * 1999-12-06 2001-11-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова 3,5-Dibromsalicylidenethiosemicarbazidopyridinecopper possessing antistaphylococcia and antistreptococcia activity
MD1812C2 (en) * 2000-12-29 2002-06-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Copper complexes as bacteria and fungi inhibitors
MD2003C2 (en) * 2001-01-10 2003-03-31 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Copper chelate compounds (II) with antimicrobial and antimycotic activity
MD2942C2 (en) * 2004-04-27 2006-06-30 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Di(µ-O)-bis(3,5-dibromosalicylidene thiosemicarbazonatocopper)
MD3124C2 (en) * 2005-05-25 2007-03-31 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Sulfanilamide-containing salicylidenethiosemicarbazidates of copper(II)
MD3032G2 (en) * 2005-10-31 2006-11-30 Государственный Университет Молд0 Sulfanilamide-containing naphthalidenethiosemicarbazidates of copper(II)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4174C1 (en) * 2011-10-25 2013-01-31 Институт Химии Академии Наук Молдовы Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties
MD4255C1 (en) * 2012-11-05 2014-05-31 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Tetraisothiocyanatocobaltate of bis(nicotinoylhydrazone)-2,6-diformil-4-methylphenol(methanol)(aqua)cobalt(II) and process for cultivation of microalga Porphyridium cruentum with the use thereof
MD4254C1 (en) * 2012-11-05 2014-05-31 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Hexafluorotitanate-bis[(dimethylglyoximato)-di-(thiocarbamide)cobalt(III)] dihydrate and process for cultivation of microalga Porphyridium cruentum with the use thereof
MD4253C1 (en) * 2012-11-05 2014-05-31 Институт Микробиологии И Биотехнологии Академии Наук Молдовы Sulphato-bis(nicotinoylhydrazone)-2,6-diacetylpyridin-cobalt(II )monomethanol trihydrate and process for cultivation of microalga Porphyridium cruentum with the use thereof
MD4327C1 (en) * 2013-10-22 2015-09-30 Институт Химии Академии Наук Молдовы N-(D8,13-Bicyclohomofarnesenoyl)-3-amino-1,2,4-triazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4326C1 (en) * 2013-10-22 2015-09-30 Институт Химии Академии Наук Молдовы N-(D8,13-Bicyclohomofarnesenoylamino)carbazole compound and process for cultivation of Nostoc linckia cyanobacterium with its use
MD4356C1 (en) * 2014-07-09 2016-02-29 Институт Химии Академии Наук Молдовы Bis[N'-(2-hydroxy-kO-benzylidene)pyridine-4-carbohydrazidate(-1)-k2N',O]iron(III) nitrate - water (2/3) and process for cultivation of microalga Porphyridium cruentum with its use
MD4366C1 (en) * 2014-07-09 2016-03-31 Институт Химии Академии Наук Молдовы Bis[1-phenyl-3-methyl-6-(pyridinium-4-il)-4,5-diaza-hexa-1,3,5-triene-1-hydroxy-6-olato-O1,N4,O6]iron(II)sulphate tetrahydrate and process for cultivation of microalga Porphyridium cruentum with its use
MD4365C1 (en) * 2014-07-09 2016-03-31 Институт Химии Академии Наук Молдовы Bis[1-phenyl-3-methyl-6-(pyridinium-4-yl)-4,5-diaza-hexa-1,3,5-triene-1,6-diolato-O1,N4,O6]iron(III) nitrate and process for cultivation of microalga Porphyridium cruentum with its use
MD4367C1 (en) * 2014-07-09 2016-03-31 Институт Химии Академии Наук Молдовы Bis[N'-(2-hydroxy-kO-3-carboxybenzilidene)pyridine-3-carbohydrazidate(-1)-k2N',O]iron(III) perchlorate - water (4/5) and process for cultivation of microalga Porphyridium cruentum with its use

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