MD4383C1 - Acetato-(8-formylquinolinethiosemicarbazono)copper(II) compound, exhibiting antibacterial activity - Google Patents
Acetato-(8-formylquinolinethiosemicarbazono)copper(II) compound, exhibiting antibacterial activityInfo
- Publication number
- MD4383C1 MD4383C1 MDA20150025A MD20150025A MD4383C1 MD 4383 C1 MD4383 C1 MD 4383C1 MD A20150025 A MDA20150025 A MD A20150025A MD 20150025 A MD20150025 A MD 20150025A MD 4383 C1 MD4383 C1 MD 4383C1
- Authority
- MD
- Moldova
- Prior art keywords
- copper
- compound
- formylquinolinethiosemicarbazono
- acetato
- antibacterial activity
- Prior art date
Links
Abstract
The invention relates to chemistry and medicine, namely to the synthesis of a new biologically active coordinative compound of copper, from the class of heterocyclic thiosemicarbazones, which may find its use in medicine as an antimicrobial agent.Summary of the invention consists in the synthesis of acetato-(8-formylquinolinethiosemicarbazono)copper(II) compound of formula:,exhibiting antibacterial activity against Staphylococcus aureus (strain 209-P), Enterococcus faecalis and Proteus vulgaris bacteria.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDA20150025A MD4383C1 (en) | 2015-03-06 | 2015-03-06 | Acetato-(8-formylquinolinethiosemicarbazono)copper(II) compound, exhibiting antibacterial activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MDA20150025A MD4383C1 (en) | 2015-03-06 | 2015-03-06 | Acetato-(8-formylquinolinethiosemicarbazono)copper(II) compound, exhibiting antibacterial activity |
Publications (2)
Publication Number | Publication Date |
---|---|
MD4383B1 MD4383B1 (en) | 2015-11-30 |
MD4383C1 true MD4383C1 (en) | 2016-06-30 |
Family
ID=54753226
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MDA20150025A MD4383C1 (en) | 2015-03-06 | 2015-03-06 | Acetato-(8-formylquinolinethiosemicarbazono)copper(II) compound, exhibiting antibacterial activity |
Country Status (1)
Country | Link |
---|---|
MD (1) | MD4383C1 (en) |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985000955A1 (en) * | 1983-08-22 | 1985-03-14 | A/S Cheminova | A biocidal, particularly fungicidal and/or bactericidal composition and thiosemicarbazones and metal complexes thereof for use in the composition |
MD195B1 (en) * | 1994-12-05 | 1995-05-31 | Univ De Stat De Medicina N Tes | Copper complexes with antistaphylococcal properties |
MD1650F1 (en) * | 1999-12-06 | 2001-04-30 | Univ Nicolae Testemitanu | 3,5-Dibromsalicylidenethiosemicarbazidopyridinecopper possessing antistaphylococcia and antistreptococcia activity |
MD1812B1 (en) * | 2000-12-29 | 2001-12-31 | Univ Nicolae Testemitanu | Copper complexes as bacteria and fungi inhibitors |
MD2003B1 (en) * | 2001-01-10 | 2002-09-30 | Univ Nicolae Testemitanu | Copper chelate compounds(II) with antimicrobial and antimycotic activity |
MD2258B1 (en) * | 2001-10-04 | 2003-09-30 | Univ Nicolae Testemitanu | Chelating copper (II) complexes active in respect of gram-positive microorganisms |
MD2942B2 (en) * | 2004-04-27 | 2005-12-31 | Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova | Di(-O)-bis(3,5-dibromosalicylidene thiosemicarbazonatocopper) |
MD4112B1 (en) * | 2010-05-17 | 2011-05-31 | Univ De Stat Din Moldova | Coordinative compounds of copper with 4-(dimethylphenyl)-thiosemicarbazones of 2-formylpyridine |
MD4127B1 (en) * | 2010-10-06 | 2011-09-30 | Univ De Stat Din Moldova | Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus |
MD4258B1 (en) * | 2012-05-31 | 2013-11-30 | Univ De Stat Din Moldova | The use of biologically active coordinative compounds of copper(II) with 4-(methoxyphenyl)thiosemicarbazones of 2-benzoylpyridine as inhibitors of Candida albicans |
-
2015
- 2015-03-06 MD MDA20150025A patent/MD4383C1/en not_active IP Right Cessation
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1985000955A1 (en) * | 1983-08-22 | 1985-03-14 | A/S Cheminova | A biocidal, particularly fungicidal and/or bactericidal composition and thiosemicarbazones and metal complexes thereof for use in the composition |
MD195B1 (en) * | 1994-12-05 | 1995-05-31 | Univ De Stat De Medicina N Tes | Copper complexes with antistaphylococcal properties |
MD1650F1 (en) * | 1999-12-06 | 2001-04-30 | Univ Nicolae Testemitanu | 3,5-Dibromsalicylidenethiosemicarbazidopyridinecopper possessing antistaphylococcia and antistreptococcia activity |
MD1812B1 (en) * | 2000-12-29 | 2001-12-31 | Univ Nicolae Testemitanu | Copper complexes as bacteria and fungi inhibitors |
MD2003B1 (en) * | 2001-01-10 | 2002-09-30 | Univ Nicolae Testemitanu | Copper chelate compounds(II) with antimicrobial and antimycotic activity |
MD2258B1 (en) * | 2001-10-04 | 2003-09-30 | Univ Nicolae Testemitanu | Chelating copper (II) complexes active in respect of gram-positive microorganisms |
MD2942B2 (en) * | 2004-04-27 | 2005-12-31 | Universitatea De Stat De Medicina Si Farmacie "Nicolae Testemitanu" Din Republica Moldova | Di(-O)-bis(3,5-dibromosalicylidene thiosemicarbazonatocopper) |
MD4112B1 (en) * | 2010-05-17 | 2011-05-31 | Univ De Stat Din Moldova | Coordinative compounds of copper with 4-(dimethylphenyl)-thiosemicarbazones of 2-formylpyridine |
MD4127B1 (en) * | 2010-10-06 | 2011-09-30 | Univ De Stat Din Moldova | Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus |
MD4258B1 (en) * | 2012-05-31 | 2013-11-30 | Univ De Stat Din Moldova | The use of biologically active coordinative compounds of copper(II) with 4-(methoxyphenyl)thiosemicarbazones of 2-benzoylpyridine as inhibitors of Candida albicans |
Non-Patent Citations (4)
Title |
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Bourosh P., Revenco M., Stratulat E., Wicher B., Gdaniec M., Korzha I. Synthesis and structure of new copper(II) coordination compounds with 8-quinoline aldehyde semicarbazones and thiosemicarbazones. Russian Journal of Inorganic Chemistry, 2014, vol. 59 (6), p. 545-557 (regăsit în Internet la 2015.06.01 URL:<http://www.researchgate.net/publication/272013567_Synthesis_and_structure_of_new_copper%28II%29_coordination_compounds_with_8-quinoline_aldehyde_semicarbazones_and_thiosemicarbazones>) * |
Revenco M., Bourosh P., Stratulat E., Gdaniec M., Lipkowski Ya., Korzha I. Synthesis and structure of copper(II) coordination compounds with 8-quinolinecarboxaldehyde thio- and 4-phenylthiosemicarbazones. Russian Journal of Inorganic Chemistry, 2010, vol. 55, nr. 9, p. 1387-1397 (regăsit în Internet la 2015.06.01 URL:<http://www.researchgate.net/publication/226036392_Synthesis_and_Structure_of_Copper%28II%29_Coordination_Compounds_with_8-Quinolinecarboxaldehyde_Thio-_and_4-Phenylthiosemicarbazones>) * |
Revenko M., Prisacari V., Dizdari A., Stratulat E., Corja I., Proca L. Synthesis, antibacterial, and antifungal activities of 8-quinolinealdehyde chalcogensemicarbazones and their copper(II) complexes. Pharmaceutical Chemistry Journal, 2011, vol. 45, nr. 6, p. 351-354 (regăsit în Internet la 2015.06.03 URL:<http://www.researchgate.net/publication/235974189_ synthesis_antibacterial_and_antifungal_activities_of_8-quinolinealdehyde_chalcogensemicarbazones_and_their_copper%28ii%29_complexes>) * |
Машковский М. Д. Лекарственные средства. Кишинэу, 1990, № 2, p. 264 * |
Also Published As
Publication number | Publication date |
---|---|
MD4383B1 (en) | 2015-11-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
MM4A | Patent for invention definitely lapsed due to non-payment of fees |