MD4174C1 - Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties - Google Patents

Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties

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Publication number
MD4174C1
MD4174C1 MDA20110096A MD20110096A MD4174C1 MD 4174 C1 MD4174 C1 MD 4174C1 MD A20110096 A MDA20110096 A MD A20110096A MD 20110096 A MD20110096 A MD 20110096A MD 4174 C1 MD4174 C1 MD 4174C1
Authority
MD
Moldova
Prior art keywords
formyl
hydroxy
naphthoic acid
antibacterial properties
thiosemicarbazone derivatives
Prior art date
Application number
MDA20110096A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD4174B1 (en
Inventor
Ana Lazarescu
Elena ZARICIUC
Daniela Cojocari
Constantin Turta
Veaceslav Gonciar
Polina Bouros
Original Assignee
Институт Химии Академии Наук Молдовы
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт Химии Академии Наук Молдовы filed Critical Институт Химии Академии Наук Молдовы
Priority to MDA20110096A priority Critical patent/MD4174C1/en
Publication of MD4174B1 publication Critical patent/MD4174B1/en
Publication of MD4174C1 publication Critical patent/MD4174C1/en

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to organic compounds from the class of thiosemicarbazones possessing antibacterial activity. The compounds can be used in medicine, veterinary medicine and agriculture.Summary of the invention consists in the synthesis of new derivatives of 4-formyl-3-hydroxy-2-naphthoic acid of the formula:where R = H (1) and C6H5 (2). The compounds exhibit bacteriostatic and bactericidal properties against pathogens S. aureus and E. coli.
MDA20110096A 2011-10-25 2011-10-25 Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties MD4174C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20110096A MD4174C1 (en) 2011-10-25 2011-10-25 Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20110096A MD4174C1 (en) 2011-10-25 2011-10-25 Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties

Publications (2)

Publication Number Publication Date
MD4174B1 MD4174B1 (en) 2012-06-30
MD4174C1 true MD4174C1 (en) 2013-01-31

Family

ID=46512856

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20110096A MD4174C1 (en) 2011-10-25 2011-10-25 Thiosemicarbazone derivatives of 4-formyl-3-hydroxy-2-naphthoic acid with antibacterial properties

Country Status (1)

Country Link
MD (1) MD4174C1 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3457301A (en) * 1965-04-29 1969-07-22 Ugine Kuhlmann Disazomethine pigments
SU437306A3 (en) * 1970-10-24 1974-07-25 Басф Аг (Фирма) The method of obtaining disazometinovogo pigment
US3839434A (en) * 1970-04-27 1974-10-01 Basf Ag Amidine substituted naphthalene carboxylic acid
MD678G2 (en) * 1996-07-17 1997-09-30 Государственный Университет Молд0 DI-(mu-O)-di[N-(2-oxo-1-naphtal)-N'-alpha-oxobenzalhydrazinecopper] dihydrate manifesting selective antimicrobic properties
MD3371G2 (en) * 2006-08-30 2008-02-29 Технический университет Молдовы Apparatus for cardan gear diagnostics
MD4127C1 (en) * 2010-10-06 2012-04-30 Государственный Университет Молд0 Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3457301A (en) * 1965-04-29 1969-07-22 Ugine Kuhlmann Disazomethine pigments
DE1569710A1 (en) * 1965-04-29 1970-07-09 Ugine Kuhlmann Disazomethine compounds, processes for their preparation and their use
US3839434A (en) * 1970-04-27 1974-10-01 Basf Ag Amidine substituted naphthalene carboxylic acid
SU437306A3 (en) * 1970-10-24 1974-07-25 Басф Аг (Фирма) The method of obtaining disazometinovogo pigment
MD678G2 (en) * 1996-07-17 1997-09-30 Государственный Университет Молд0 DI-(mu-O)-di[N-(2-oxo-1-naphtal)-N'-alpha-oxobenzalhydrazinecopper] dihydrate manifesting selective antimicrobic properties
MD3371G2 (en) * 2006-08-30 2008-02-29 Технический университет Молдовы Apparatus for cardan gear diagnostics
MD4127C1 (en) * 2010-10-06 2012-04-30 Государственный Университет Молд0 Use of di(m-S)-bis{chloro-[1-(pyridine-2-yl)ethanone-4-methylthiosemicarbazonato(1-)]copper} as substance with antimicrobial activity against Staphylococcus aureus

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
D.X. West, J.J. Ingram, N.M. Kozub, G.A. Bain, A.E. Liberta, Trans. Met. Chem. 21 (1996), p. 213 *
J. Marthakutty, V. Suni, Maliyeckal R., et al. Polyhedron, 23 (2004), p. 3069 *
L. Latheef, E. Manoj, M.R.P. Kurup, Acta Crystallogr., Sect. C 62 (2006), p. 16 *
M. B. Ferrari, F. Bisceglie, C. Casoli, et al. J. Med. Chem. 48 (2005), p. 1671 *
M.A. Ali, A.H. Mirza, A.M.S. Hossain, M. Nazimuddin, Polyhedron 20 (2001), p. 1045 *
Yu.K. Bhoon, Polyhedron, 2 (1983) nr. 5, p. 365 *

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Publication number Publication date
MD4174B1 (en) 2012-06-30

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FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees