MC1914A1 - Nucleosides therapeutiques - Google Patents

Nucleosides therapeutiques

Info

Publication number
MC1914A1
MC1914A1 MC881958A MC1958A MC1914A1 MC 1914 A1 MC1914 A1 MC 1914A1 MC 881958 A MC881958 A MC 881958A MC 1958 A MC1958 A MC 1958A MC 1914 A1 MC1914 A1 MC 1914A1
Authority
MC
Monaco
Prior art keywords
compound
formula
group
azido
pyrimidinone
Prior art date
Application number
MC881958A
Other languages
English (en)
French (fr)
Inventor
Litster Rideout Janet
Andrew Freeman George
Ray Shaver Sammy
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878706176A external-priority patent/GB8706176D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MC1914A1 publication Critical patent/MC1914A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
MC881958A 1987-03-16 1988-03-15 Nucleosides therapeutiques MC1914A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878706176A GB8706176D0 (en) 1987-03-16 1987-03-16 Therapeutic nucleosides
US13880887A 1987-12-28 1987-12-28

Publications (1)

Publication Number Publication Date
MC1914A1 true MC1914A1 (fr) 1989-04-06

Family

ID=26292019

Family Applications (1)

Application Number Title Priority Date Filing Date
MC881958A MC1914A1 (fr) 1987-03-16 1988-03-15 Nucleosides therapeutiques

Country Status (18)

Country Link
EP (1) EP0287215B1 (enExample)
JP (1) JPS63290894A (enExample)
AP (1) AP73A (enExample)
AU (1) AU601556B2 (enExample)
CA (1) CA1321387C (enExample)
DE (1) DE3872028T2 (enExample)
DK (1) DK140588A (enExample)
ES (1) ES2039615T3 (enExample)
FI (1) FI881216A7 (enExample)
GR (1) GR3005506T3 (enExample)
HU (1) HU199865B (enExample)
IL (1) IL85738A0 (enExample)
MC (1) MC1914A1 (enExample)
NO (1) NO881135L (enExample)
NZ (1) NZ223880A (enExample)
PH (1) PH24812A (enExample)
PL (1) PL271196A1 (enExample)
PT (1) PT86982B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8706176D0 (en) * 1987-03-16 1987-04-23 Wellcome Found Therapeutic nucleosides
US4804651A (en) * 1987-06-09 1989-02-14 Board Of Regents, The University Of Texas System Methods and compositions for the treatment of psoriasis
US5077280A (en) * 1988-04-12 1991-12-31 Brown University Research Foundation Treatment of viral infections
GB8902041D0 (en) * 1989-01-31 1989-03-22 Tanabe Seiyaku Co Antiviral agent and novel nucleoside
US5220003A (en) * 1991-03-29 1993-06-15 The Regents Of The University Of California Process for the synthesis of 2',3'-dideoxynucleosides
WO1992020816A1 (en) * 1991-05-15 1992-11-26 Yale University Determination of prodrugs metabolizable by the liver and therapeutic use thereof
RU2111970C1 (ru) * 1996-06-25 1998-05-27 Иван Игоревич Федоров 3'-оксимино-2',3'-дидезоксинуклеозиды

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468384A (en) * 1982-01-05 1984-08-28 The Research Foundation Of State University Of New York Method for the inhibition of the replication of DNA viruses with 5-substituted 2-pyrimidinone nucleosides
DK166805B1 (da) * 1985-03-16 1993-07-19 Wellcome Found Threo-isomeren af 3'-azido-3'-deoxythymidin til anvendelse ved behandling af eller profylakse for humane retrovirusinfektioner, anvendelse af forbindelsen til fremstilling af et laegemiddel med naevnte indikation og farmaceutisk praeparat indeholdende forbindelsen
MC1742A1 (fr) * 1985-03-16 1987-02-26 Wellcome Found Procede pour preparer un derive de 3'-azido-3'desoxythymigline et procede pour preparer une formulation pharmaceutique le contenant
ATE190064T1 (de) * 1985-09-17 2000-03-15 Wellcome Found Kombination therapeutische nukleoside mit weiteren therapeutisch wirksamen komponenten.

Also Published As

Publication number Publication date
FI881216L (fi) 1988-09-17
AP8800085A0 (en) 1988-02-01
NZ223880A (en) 1991-06-25
PL271196A1 (en) 1988-12-08
HU199865B (en) 1990-03-28
NO881135L (no) 1988-09-19
PT86982B (pt) 1992-06-30
EP0287215B1 (en) 1992-06-17
CA1321387C (en) 1993-08-17
PH24812A (en) 1990-10-30
EP0287215A2 (en) 1988-10-19
FI881216A0 (fi) 1988-03-15
DE3872028D1 (en) 1992-07-23
AU601556B2 (en) 1990-09-13
IL85738A0 (en) 1988-08-31
ES2039615T3 (es) 1993-10-01
GR3005506T3 (enExample) 1993-06-07
JPS63290894A (ja) 1988-11-28
FI881216A7 (fi) 1988-09-17
HUT47591A (en) 1989-03-28
DE3872028T2 (de) 1993-01-14
DK140588A (da) 1988-09-17
DK140588D0 (da) 1988-03-15
AU1318588A (en) 1988-09-15
PT86982A (pt) 1988-04-01
NO881135D0 (no) 1988-03-15
AP73A (en) 1990-03-01
EP0287215A3 (en) 1990-01-10

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