MA54100A - Dérivés de thiazine en tant qu'inhibiteurs de bêta-sécrétase et procédés d'utilisation - Google Patents

Dérivés de thiazine en tant qu'inhibiteurs de bêta-sécrétase et procédés d'utilisation

Info

Publication number
MA54100A
MA54100A MA054100A MA54100A MA54100A MA 54100 A MA54100 A MA 54100A MA 054100 A MA054100 A MA 054100A MA 54100 A MA54100 A MA 54100A MA 54100 A MA54100 A MA 54100A
Authority
MA
Morocco
Prior art keywords
beta
methods
secretase inhibitors
thiazine derivatives
thiazine
Prior art date
Application number
MA054100A
Other languages
English (en)
French (fr)
Inventor
Matthew P Bourbeau
Paul E Harrington
Qingyian Liu
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of MA54100A publication Critical patent/MA54100A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
MA054100A 2016-12-15 2017-12-13 Dérivés de thiazine en tant qu'inhibiteurs de bêta-sécrétase et procédés d'utilisation MA54100A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662434714P 2016-12-15 2016-12-15

Publications (1)

Publication Number Publication Date
MA54100A true MA54100A (fr) 2021-10-20

Family

ID=60888745

Family Applications (1)

Application Number Title Priority Date Filing Date
MA054100A MA54100A (fr) 2016-12-15 2017-12-13 Dérivés de thiazine en tant qu'inhibiteurs de bêta-sécrétase et procédés d'utilisation

Country Status (9)

Country Link
US (1) US10889579B2 (enExample)
EP (1) EP3555084B1 (enExample)
JP (1) JP7149272B2 (enExample)
AU (1) AU2017376444B2 (enExample)
CA (1) CA3047288A1 (enExample)
ES (1) ES2910791T3 (enExample)
MA (1) MA54100A (enExample)
MX (1) MX388697B (enExample)
WO (1) WO2018112083A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
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JP7148518B2 (ja) 2016-12-15 2022-10-05 アムジエン・インコーポレーテツド β－セクレターゼ阻害剤としての二環式チアジンおよびオキサジン誘導体ならびに使用方法
MX387729B (es) 2016-12-15 2025-03-18 Amgen Inc Derivados de dióxido de 1,4-tiazina y dióxido 1,2,4-tiadiazina como inhibidores de beta-secretasa y métodos de uso.
WO2018112083A1 (en) 2016-12-15 2018-06-21 Amgen Inc. Thiazine derivatives as beta-secretase inhibitors and methods of use

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Also Published As

Publication number Publication date
JP7149272B2 (ja) 2022-10-06
WO2018112083A1 (en) 2018-06-21
MX2019007102A (es) 2019-12-16
AU2017376444B2 (en) 2021-09-30
EP3555084B1 (en) 2022-03-16
MX388697B (es) 2025-03-20
CA3047288A1 (en) 2018-06-21
JP2020503292A (ja) 2020-01-30
US10889579B2 (en) 2021-01-12
EP3555084A1 (en) 2019-10-23
AU2017376444A1 (en) 2019-07-04
ES2910791T3 (es) 2022-05-13
US20200062743A1 (en) 2020-02-27

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