MA51611A - Inhibiteurs de pi4kiiibêta - Google Patents

Inhibiteurs de pi4kiiibêta

Info

Publication number
MA51611A
MA51611A MA051611A MA51611A MA51611A MA 51611 A MA51611 A MA 51611A MA 051611 A MA051611 A MA 051611A MA 51611 A MA51611 A MA 51611A MA 51611 A MA51611 A MA 51611A
Authority
MA
Morocco
Prior art keywords
inhibitors
Prior art date
Application number
MA051611A
Other languages
English (en)
Inventor
Nicholas Paul Barton
Sophie Marie Bertrand
Kenneth Down
Matthew Gray
Original Assignee
Glaxosmithkline Ip Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1800734.4A external-priority patent/GB201800734D0/en
Priority claimed from GBGB1817616.4A external-priority patent/GB201817616D0/en
Application filed by Glaxosmithkline Ip Dev Ltd filed Critical Glaxosmithkline Ip Dev Ltd
Publication of MA51611A publication Critical patent/MA51611A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
MA051611A 2018-01-17 2019-01-15 Inhibiteurs de pi4kiiibêta MA51611A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1800734.4A GB201800734D0 (en) 2018-01-17 2018-01-17 Novel compounds
GBGB1817616.4A GB201817616D0 (en) 2018-10-29 2018-10-29 Novel compounds

Publications (1)

Publication Number Publication Date
MA51611A true MA51611A (fr) 2021-04-21

Family

ID=65033598

Family Applications (1)

Application Number Title Priority Date Filing Date
MA051611A MA51611A (fr) 2018-01-17 2019-01-15 Inhibiteurs de pi4kiiibêta

Country Status (19)

Country Link
US (2) US11649238B2 (fr)
EP (1) EP3740489A1 (fr)
JP (2) JP7133023B2 (fr)
KR (1) KR102523513B1 (fr)
CN (2) CN111868063B (fr)
AR (1) AR114082A1 (fr)
AU (1) AU2019208416B2 (fr)
BR (1) BR112020014431A2 (fr)
CA (1) CA3088347A1 (fr)
CL (1) CL2020001875A1 (fr)
CO (1) CO2020008887A2 (fr)
IL (1) IL276013B2 (fr)
MA (1) MA51611A (fr)
MX (1) MX2020007521A (fr)
PH (1) PH12020551034A1 (fr)
SG (1) SG11202006453SA (fr)
TW (1) TWI795510B (fr)
UY (1) UY38051A (fr)
WO (1) WO2019141694A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111868063B (zh) * 2018-01-17 2023-08-01 葛兰素史克知识产权开发有限公司 PI4KIIIβ抑制剂
CA3173172A1 (fr) 2020-03-26 2021-09-30 Christopher D. Kane Inhibiteurs de cathepsine pour la prevention ou le traitement d'infections virales
CA3198344A1 (fr) 2020-11-20 2022-05-27 Patrick T. GUNNING Procedes et composition pour effectuer des modifications de kras
GB2617477A (en) 2020-11-20 2023-10-11 2692372 Ontario Inc Benzenesulfonamide derivatives and uses thereof

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GB0201677D0 (en) 2002-01-25 2002-03-13 Glaxo Group Ltd Medicament dispenser
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MXPA05002571A (es) 2002-09-04 2005-09-08 Schering Corp Pirazolopirimidinas como inhibidores de cinasa dependientes de ciclina.
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TWI453207B (zh) * 2008-09-08 2014-09-21 Signal Pharm Llc 胺基三唑并吡啶,其組合物及使用其之治療方法
UA110324C2 (en) * 2009-07-02 2015-12-25 Genentech Inc Jak inhibitory compounds based on pyrazolo pyrimidine
EP2548877A1 (fr) * 2011-07-19 2013-01-23 MSD Oss B.V. Dérivés de 4-(pyridine condensée à 5 chaînons)benzamide comme inhibiteurs de BTK
CA2844086A1 (fr) * 2011-08-19 2013-02-28 Glaxo Group Limited Composes benzofuranes pour le traitement d'infections par le virus de l'hepatite c
GB201115665D0 (en) 2011-09-09 2011-10-26 Univ Leuven Kath Autoimmune and inflammatory disorder therapy
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EP2634190A1 (fr) 2012-03-01 2013-09-04 Lead Discovery Center GmbH dérivés de pyrazolo-triazine en tant qu'inhibiteurs des kinases dépendantes de la cycline
CA2893704C (fr) 2012-12-20 2020-12-15 Ucb Biopharma Sprl Derives de pyrazolo-pyrimidine therapeutiquement actifs comme inhibiteurs d'activite de phosphatidyleinositol-4-kinase iiib (pi4kiiib)
WO2014113942A1 (fr) * 2013-01-23 2014-07-31 Merck Sharp & Dohme Corp. Inhibiteurs de btk
US9580431B2 (en) * 2013-03-13 2017-02-28 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
CA2935658C (fr) * 2014-01-22 2023-02-21 Apodemus Ab Derives de pyrazolo[1,5-a]pyrimidine-7-amine utiles en therapie
GB201410816D0 (en) 2014-06-17 2014-07-30 Ucb Biopharma Sprl And Katholieke Universiteit Leuven Therapeutic agents
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WO2018134265A1 (fr) 2017-01-17 2018-07-26 Forrest Michael David Inhibiteurs thérapeutiques du mode inverse de l'atp synthase
KR102551432B1 (ko) 2017-03-31 2023-07-05 바스프 에스이 동물 해충 퇴치를 위한 피리미디늄 화합물 및 이의 혼합물
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JP2021518836A (ja) 2018-01-17 2021-08-05 オーリジーン ディスカバリー テクノロジーズ リミテッド 抗癌剤としての置換されたアルキニレン化合物
CN111868063B (zh) * 2018-01-17 2023-08-01 葛兰素史克知识产权开发有限公司 PI4KIIIβ抑制剂
CA3115968A1 (fr) 2018-10-29 2020-05-07 Nippon Soda Co., Ltd. Compose (hetero)arylimidazole et agent de lutte contre les organismes nuisibles
PE20211780A1 (es) 2018-10-29 2021-09-08 Myokardia Inc Compuestos de pirimidinodiona biciclicos sustituidos con tetrahidropirano (thp)

Also Published As

Publication number Publication date
CO2020008887A2 (es) 2020-07-31
EP3740489A1 (fr) 2020-11-25
IL276013A (en) 2020-08-31
IL276013B1 (en) 2023-11-01
JP2022172223A (ja) 2022-11-15
MX2020007521A (es) 2022-12-05
CN111868063A (zh) 2020-10-30
IL276013B2 (en) 2024-03-01
AU2019208416B2 (en) 2021-07-29
PH12020551034A1 (en) 2021-09-06
JP7338017B2 (ja) 2023-09-04
AU2019208416A1 (en) 2020-07-23
TWI795510B (zh) 2023-03-11
RU2020123034A (ru) 2022-02-17
US11649238B2 (en) 2023-05-16
CA3088347A1 (fr) 2019-07-25
JP7133023B2 (ja) 2022-09-07
KR20200109343A (ko) 2020-09-22
US20210387988A1 (en) 2021-12-16
TW201940173A (zh) 2019-10-16
SG11202006453SA (en) 2020-08-28
US20230124394A1 (en) 2023-04-20
KR102523513B1 (ko) 2023-04-18
CN111868063B (zh) 2023-08-01
CN117069728A (zh) 2023-11-17
BR112020014431A2 (pt) 2020-12-01
UY38051A (es) 2019-08-30
CL2020001875A1 (es) 2021-02-12
WO2019141694A1 (fr) 2019-07-25
AR114082A1 (es) 2020-07-22
JP2021510711A (ja) 2021-04-30

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