DK3720840T3 - Cathepsinhæmmere - Google Patents
Cathepsinhæmmere Download PDFInfo
- Publication number
- DK3720840T3 DK3720840T3 DK18839759.0T DK18839759T DK3720840T3 DK 3720840 T3 DK3720840 T3 DK 3720840T3 DK 18839759 T DK18839759 T DK 18839759T DK 3720840 T3 DK3720840 T3 DK 3720840T3
- Authority
- DK
- Denmark
- Prior art keywords
- catheps
- inhibitors
- catheps inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/14—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL2020021A NL2020021B1 (en) | 2017-12-05 | 2017-12-05 | Cathepsin inhibitors |
NL2021544 | 2018-09-03 | ||
PCT/NL2018/050810 WO2019112426A1 (en) | 2017-12-05 | 2018-12-05 | Cathepsin inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3720840T3 true DK3720840T3 (da) | 2022-03-21 |
Family
ID=65228614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK18839759.0T DK3720840T3 (da) | 2017-12-05 | 2018-12-05 | Cathepsinhæmmere |
Country Status (5)
Country | Link |
---|---|
US (3) | US11174224B2 (da) |
EP (2) | EP4046987A1 (da) |
DK (1) | DK3720840T3 (da) |
ES (1) | ES2908999T3 (da) |
WO (1) | WO2019112426A1 (da) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4046987A1 (en) * | 2017-12-05 | 2022-08-24 | Academisch Ziekenhuis Leiden (h.o.d.n. LUMC) | Cathepsin inhibitors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002145849A (ja) * | 2000-11-10 | 2002-05-22 | Kyorin Pharmaceut Co Ltd | アルキニルアミノ酸誘導体及びその製造法 |
PT1482924E (pt) | 2002-03-05 | 2008-08-27 | Axys Pharm Inc | Inibidores de proteases da cisteína catepsina |
EP4046987A1 (en) * | 2017-12-05 | 2022-08-24 | Academisch Ziekenhuis Leiden (h.o.d.n. LUMC) | Cathepsin inhibitors |
-
2018
- 2018-12-05 EP EP22150956.5A patent/EP4046987A1/en active Pending
- 2018-12-05 WO PCT/NL2018/050810 patent/WO2019112426A1/en unknown
- 2018-12-05 ES ES18839759T patent/ES2908999T3/es active Active
- 2018-12-05 EP EP18839759.0A patent/EP3720840B1/en active Active
- 2018-12-05 US US16/770,200 patent/US11174224B2/en active Active
- 2018-12-05 DK DK18839759.0T patent/DK3720840T3/da active
-
2021
- 2021-10-20 US US17/506,096 patent/US11820734B2/en active Active
-
2023
- 2023-10-10 US US18/378,221 patent/US20240182409A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3720840A1 (en) | 2020-10-14 |
US20240182409A1 (en) | 2024-06-06 |
ES2908999T3 (es) | 2022-05-04 |
EP3720840B1 (en) | 2022-01-19 |
EP4046987A1 (en) | 2022-08-24 |
US11820734B2 (en) | 2023-11-21 |
WO2019112426A1 (en) | 2019-06-13 |
US11174224B2 (en) | 2021-11-16 |
US20220227705A1 (en) | 2022-07-21 |
US20200385341A1 (en) | 2020-12-10 |
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