MA51075A - Procédés et compositions pour traiter des troubles à l'aide de polypeptides de follistatine - Google Patents
Procédés et compositions pour traiter des troubles à l'aide de polypeptides de follistatineInfo
- Publication number
- MA51075A MA51075A MA051075A MA51075A MA51075A MA 51075 A MA51075 A MA 51075A MA 051075 A MA051075 A MA 051075A MA 51075 A MA51075 A MA 51075A MA 51075 A MA51075 A MA 51075A
- Authority
- MA
- Morocco
- Prior art keywords
- compositions
- methods
- treating disorders
- follistatin polypeptides
- follistatin
- Prior art date
Links
- 102000016970 Follistatin Human genes 0.000 title 1
- 108010014612 Follistatin Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4707—Muscular dystrophy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/06—Anabolic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Marine Sciences & Fisheries (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462007908P | 2014-06-04 | 2014-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA51075A true MA51075A (fr) | 2020-10-14 |
Family
ID=54767384
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA051075A MA51075A (fr) | 2014-06-04 | 2015-06-04 | Procédés et compositions pour traiter des troubles à l'aide de polypeptides de follistatine |
| MA051074A MA51074A (fr) | 2014-06-04 | 2015-06-04 | Procédés et compositions pour traiter des troubles à l'aide de polypeptides de follistatine |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA051074A MA51074A (fr) | 2014-06-04 | 2015-06-04 | Procédés et compositions pour traiter des troubles à l'aide de polypeptides de follistatine |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10023621B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3152237B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6568110B2 (cg-RX-API-DMAC7.html) |
| KR (4) | KR102305109B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN106795224B (cg-RX-API-DMAC7.html) |
| AU (2) | AU2015269333B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112016028520A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2950754C (cg-RX-API-DMAC7.html) |
| EA (2) | EA202090632A1 (cg-RX-API-DMAC7.html) |
| MA (2) | MA51075A (cg-RX-API-DMAC7.html) |
| MX (2) | MX382908B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015187977A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7612041B2 (en) | 2005-11-23 | 2009-11-03 | Acceleron Pharma Inc. | Isolated activin-binding ActRIIa polypeptide comprising the SEQ ID NO: 7 and uses for promoting bone growth |
| US20100015144A1 (en) | 2008-06-26 | 2010-01-21 | Acceleron Pharma Inc. | Methods for dosing an activin-actriia antagonist and monitoring of treated patients |
| EA201590719A1 (ru) | 2013-01-25 | 2015-12-30 | Шир Хьюман Дженетик Терапис, Инк. | Фоллистатин в лечении мышечной дистрофии дюшенна |
| JP6568110B2 (ja) | 2014-06-04 | 2019-08-28 | アクセルロン ファーマ, インコーポレイテッド | フォリスタチンポリペプチドによる障害の処置のための方法および組成物 |
| US10010498B2 (en) | 2014-06-04 | 2018-07-03 | Acceleron Pharma Inc. | Methods for treatment of amyotrophic lateral sclerosis with follistatin fusion proteins |
| BR122023023170A2 (pt) | 2014-06-13 | 2024-02-20 | Acceleron Pharma Inc. | Uso de um antagonista de actrii no tratamento ou prevenção de úlcera cutânea associada com beta-talassemia |
| JP2018510637A (ja) * | 2015-03-26 | 2018-04-19 | アクセルロン ファーマ, インコーポレイテッド | フォリスタチン関連融合タンパク質およびその使用 |
| KR20180137487A (ko) * | 2016-03-04 | 2018-12-27 | 샤이어 휴먼 지네틱 테라피즈 인크. | 재조합 폴리스타틴-fc 융합 단백질 및 듀시엔형 근이영양증 치료에서의 용도 |
| US10905766B2 (en) | 2017-03-23 | 2021-02-02 | Oregon State University | Therapeutic compositions and methods for treatment of muscle wasting diseases |
| KR101822633B1 (ko) * | 2017-08-22 | 2018-01-26 | (주)진셀팜 | 폴리스타틴 유래 생리활성 펩타이드, 및 이의 용도 |
| WO2019046903A1 (en) * | 2017-09-08 | 2019-03-14 | Baker Heart and Diabetes Institute | THERAPEUTIC METHOD FOR INCREASING MUSCLE MASS IN A SUBJECT |
| CN108218985B (zh) * | 2017-12-12 | 2021-04-30 | 山西农业大学 | 一种利用特征多肽制备fst蛋白特异性抗体的方法及其应用 |
| AU2019233929B2 (en) * | 2018-03-16 | 2025-05-29 | Immusoft Corporation | B cells genetically engineered to secrete follistatin and methods of using the same to treat follistatin-related diseases, conditions, disorders and to enhance muscle growth and strength |
| WO2019178759A1 (zh) * | 2018-03-21 | 2019-09-26 | 维多利亚生物医学控股股份有限公司 | 促进局部肌肉增长、减缓或防止局部肌肉萎缩的组合物及其用途 |
| WO2019191204A1 (en) * | 2018-03-28 | 2019-10-03 | Acceleron Pharma Inc. | Follistatin polypeptides for the treatment of muscle contracture |
| CA3100734A1 (en) * | 2018-05-17 | 2019-11-21 | Housey Pharmaceutical Research Laboratories, L.L.C. | Inhibition of follistatin |
| WO2020046466A1 (en) * | 2018-08-29 | 2020-03-05 | Myos Rens Technology, Inc. | Methods for alleviating, inhibiting or reversing muscle disuse atrophy in mammals |
| WO2022098812A1 (en) | 2020-11-04 | 2022-05-12 | Keros Therapeutics, Inc. | Methods of treating iron overload |
| EP4540274A1 (en) | 2022-06-15 | 2025-04-23 | UCB Biopharma SRL | Follistatin-fc fusion proteins |
| CA3259309A1 (en) | 2022-06-15 | 2023-12-21 | UCB Biopharma SRL | Fusion protein for the prevention, treatment or improvement of kidney disease |
| WO2024121351A1 (en) * | 2022-12-07 | 2024-06-13 | Lodberg Andreas | Extracellular matrix binding compounds for the localized loading of therapeutic or diagnostic agents |
| WO2025157262A1 (en) * | 2024-01-25 | 2025-07-31 | Sichuan Real & Best Biotech Co., Ltd. | Nucleic acids encoding follistatin and uses thereof |
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| US5182375A (en) | 1987-08-28 | 1993-01-26 | The Salk Institute For Biological Studies | DNA encoding follistatin |
| US5041538A (en) | 1987-08-28 | 1991-08-20 | The Salk Institute For Biological Studies | Mammalian follistatin |
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| JP5773868B2 (ja) * | 2008-06-26 | 2015-09-02 | アクセルロン ファーマ, インコーポレイテッド | アクチビン−ActRIIaのアンタゴニストおよび赤血球レベルを高めるためのその使用 |
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| MX352929B (es) | 2010-11-05 | 2017-12-13 | Zymeworks Inc | DISEÑO DE ANTICUERPOS HETERODIMÉRICOS ESTABLES CON MUTACIONES EN EL DOMINIO Fc. |
| EP2834260A4 (en) | 2012-04-02 | 2016-08-10 | Moderna Therapeutics Inc | MODIFIED POLYNUCLEOTIDES FOR THE PREPARATION OF MEMBRANE PROTEINS |
| ES2663993T3 (es) | 2012-05-17 | 2018-04-17 | Paranta Biosciences Limited | Uso de folistatina o de un inhibidor de activina para prevenir o tratar la disfunción del injerto de tejido |
| ES3049487T3 (en) * | 2012-06-27 | 2025-12-16 | Meiragtx Uk Ii Ltd | Combination for treating an inflammatory disorder |
| EA201590719A1 (ru) * | 2013-01-25 | 2015-12-30 | Шир Хьюман Дженетик Терапис, Инк. | Фоллистатин в лечении мышечной дистрофии дюшенна |
| WO2014187807A1 (en) * | 2013-05-21 | 2014-11-27 | Arcarios B.V. | Follistatin derivatives |
| US10010498B2 (en) | 2014-06-04 | 2018-07-03 | Acceleron Pharma Inc. | Methods for treatment of amyotrophic lateral sclerosis with follistatin fusion proteins |
| JP6568110B2 (ja) | 2014-06-04 | 2019-08-28 | アクセルロン ファーマ, インコーポレイテッド | フォリスタチンポリペプチドによる障害の処置のための方法および組成物 |
| JP2018510637A (ja) | 2015-03-26 | 2018-04-19 | アクセルロン ファーマ, インコーポレイテッド | フォリスタチン関連融合タンパク質およびその使用 |
| JP2020519291A (ja) | 2017-05-12 | 2020-07-02 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | 組み換えフォリスタチン−fc融合タンパク質およびデュシェンヌ型筋ジストロフィーの治療における使用 |
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2015
- 2015-06-04 JP JP2016570806A patent/JP6568110B2/ja not_active Expired - Fee Related
- 2015-06-04 CA CA2950754A patent/CA2950754C/en active Active
- 2015-06-04 WO PCT/US2015/034245 patent/WO2015187977A1/en not_active Ceased
- 2015-06-04 EA EA202090632A patent/EA202090632A1/ru unknown
- 2015-06-04 KR KR1020207018965A patent/KR102305109B1/ko not_active Expired - Fee Related
- 2015-06-04 MA MA051075A patent/MA51075A/fr unknown
- 2015-06-04 EA EA201692529A patent/EA035455B1/ru not_active IP Right Cessation
- 2015-06-04 AU AU2015269333A patent/AU2015269333B2/en not_active Ceased
- 2015-06-04 CN CN201580041740.2A patent/CN106795224B/zh not_active Expired - Fee Related
- 2015-06-04 BR BR112016028520A patent/BR112016028520A2/pt not_active Application Discontinuation
- 2015-06-04 MX MX2016015868A patent/MX382908B/es unknown
- 2015-06-04 MA MA051074A patent/MA51074A/fr unknown
- 2015-06-04 KR KR1020177000297A patent/KR102077286B1/ko not_active Expired - Fee Related
- 2015-06-04 EP EP15802909.0A patent/EP3152237B1/en active Active
- 2015-06-04 EP EP20160287.7A patent/EP3721892B1/en active Active
- 2015-06-04 US US14/731,009 patent/US10023621B2/en active Active
- 2015-06-04 KR KR1020217029755A patent/KR20210119546A/ko not_active Ceased
- 2015-06-04 CN CN202110533308.2A patent/CN113583104A/zh active Pending
- 2015-06-04 KR KR1020207003791A patent/KR102132144B1/ko not_active Expired - Fee Related
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2016
- 2016-12-01 MX MX2021006017A patent/MX2021006017A/es unknown
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2018
- 2018-06-12 US US16/006,025 patent/US10954279B2/en active Active
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2019
- 2019-08-01 JP JP2019142333A patent/JP6856716B2/ja not_active Expired - Fee Related
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2020
- 2020-08-03 AU AU2020210315A patent/AU2020210315A1/en not_active Abandoned
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2021
- 2021-03-18 JP JP2021044545A patent/JP2021095416A/ja active Pending
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