MA46204A - Formes cristallines d'un inhibiteur de lysyl oxydase de type 2 et leurs procédés de fabrication - Google Patents
Formes cristallines d'un inhibiteur de lysyl oxydase de type 2 et leurs procédés de fabricationInfo
- Publication number
- MA46204A MA46204A MA046204A MA46204A MA46204A MA 46204 A MA46204 A MA 46204A MA 046204 A MA046204 A MA 046204A MA 46204 A MA46204 A MA 46204A MA 46204 A MA46204 A MA 46204A
- Authority
- MA
- Morocco
- Prior art keywords
- inhibitor
- manufacturing
- methods
- crystalline forms
- lysyl oxidase
- Prior art date
Links
- 102000004669 Protein-Lysine 6-Oxidase Human genes 0.000 title 1
- 108010003894 Protein-Lysine 6-Oxidase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662384596P | 2016-09-07 | 2016-09-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA46204A true MA46204A (fr) | 2021-03-17 |
Family
ID=61561660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA046204A MA46204A (fr) | 2016-09-07 | 2017-09-06 | Formes cristallines d'un inhibiteur de lysyl oxydase de type 2 et leurs procédés de fabrication |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10774069B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3510023B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP7079772B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102587178B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN109983006B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017324445A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112019004517A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3036064A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA201990621A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL265192A (cg-RX-API-DMAC7.html) |
| MA (1) | MA46204A (cg-RX-API-DMAC7.html) |
| MX (1) | MX390964B (cg-RX-API-DMAC7.html) |
| SG (1) | SG11201901999XA (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018048943A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA034891B1 (ru) | 2015-03-06 | 2020-04-02 | Фармакеа, Инк. | Фторированные ингибиторы лизилоксидазоподобного фермента-2 и их применение |
| EP3265445B1 (en) * | 2015-03-06 | 2021-05-05 | Pharmakea, Inc. | Lysyl oxidase-like 2 inhibitors and uses thereof |
| AU2017218889A1 (en) | 2016-02-09 | 2018-08-30 | Pharmakea, Inc. | Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof |
| WO2018048942A1 (en) | 2016-09-07 | 2018-03-15 | Pharmakea, Inc. | Uses of a lysyl oxidase-like 2 inhibitor |
| CA3036064A1 (en) | 2016-09-07 | 2018-03-15 | Pharmakea, Inc. | Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making |
| GB201716871D0 (en) | 2017-10-13 | 2017-11-29 | Inst Of Cancer Research: Royal Cancer Hospital | Compounds |
| CN114487139B (zh) * | 2020-10-27 | 2025-01-14 | 鲁南制药集团股份有限公司 | 一种盐酸西替利嗪有关物质的检测方法 |
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| FI20030030A0 (fi) | 2003-01-09 | 2003-01-09 | Orion Corp | Uusia yhdisteitä |
| SI1638551T1 (sl) | 2003-05-19 | 2012-04-30 | Irm Llc | Imunosupresivne spojine in sestavki |
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| US20070270430A1 (en) | 2004-09-10 | 2007-11-22 | Pfzer Inc | Methods of Treating Cognitive Disorders Using Pyridyloxymethyl and Benzisoxazole Azabicyclic Derivatives |
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| WO2006052546A2 (en) | 2004-11-04 | 2006-05-18 | Neurogen Corporation | Pyrazolylmethyl heteroaryl derivatives |
| DE102004056226A1 (de) | 2004-11-22 | 2006-05-24 | Burchardt, Elmar Reinhold, Dr.Dr. | Neuartige Inhibitoren der Lysyloxidase |
| ATE440091T1 (de) | 2005-01-31 | 2009-09-15 | Merck & Co Inc | Antidiabetische bicyclische verbindungen |
| AR055041A1 (es) | 2005-03-23 | 2007-08-01 | Merck Frosst Canada Ltd | Tiadiazoles y oxadiazoles como inhibidores de la sintesis de leucotrienos. composiciones farmaceuticas. |
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| EP3265445B1 (en) | 2015-03-06 | 2021-05-05 | Pharmakea, Inc. | Lysyl oxidase-like 2 inhibitors and uses thereof |
| EA034891B1 (ru) | 2015-03-06 | 2020-04-02 | Фармакеа, Инк. | Фторированные ингибиторы лизилоксидазоподобного фермента-2 и их применение |
| CA3036064A1 (en) | 2016-09-07 | 2018-03-15 | Pharmakea, Inc. | Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making |
| WO2018048942A1 (en) | 2016-09-07 | 2018-03-15 | Pharmakea, Inc. | Uses of a lysyl oxidase-like 2 inhibitor |
-
2017
- 2017-09-06 CA CA3036064A patent/CA3036064A1/en active Pending
- 2017-09-06 US US16/331,095 patent/US10774069B2/en active Active
- 2017-09-06 EP EP17849479.5A patent/EP3510023B1/en active Active
- 2017-09-06 CN CN201780068733.0A patent/CN109983006B/zh active Active
- 2017-09-06 MX MX2019002615A patent/MX390964B/es unknown
- 2017-09-06 AU AU2017324445A patent/AU2017324445A1/en not_active Abandoned
- 2017-09-06 WO PCT/US2017/050332 patent/WO2018048943A1/en not_active Ceased
- 2017-09-06 MA MA046204A patent/MA46204A/fr unknown
- 2017-09-06 JP JP2019512640A patent/JP7079772B2/ja active Active
- 2017-09-06 SG SG11201901999XA patent/SG11201901999XA/en unknown
- 2017-09-06 BR BR112019004517-1A patent/BR112019004517A2/pt not_active IP Right Cessation
- 2017-09-06 EA EA201990621A patent/EA201990621A1/ru unknown
- 2017-09-06 KR KR1020197009870A patent/KR102587178B1/ko active Active
-
2019
- 2019-03-06 IL IL265192A patent/IL265192A/en unknown
-
2020
- 2020-08-03 US US16/983,759 patent/US11459309B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EA201990621A1 (ru) | 2019-09-30 |
| US11459309B2 (en) | 2022-10-04 |
| US20200361901A1 (en) | 2020-11-19 |
| EP3510023A4 (en) | 2020-03-18 |
| CN109983006A (zh) | 2019-07-05 |
| MX2019002615A (es) | 2019-10-15 |
| WO2018048943A1 (en) | 2018-03-15 |
| US10774069B2 (en) | 2020-09-15 |
| MX390964B (es) | 2025-03-21 |
| KR20190052040A (ko) | 2019-05-15 |
| SG11201901999XA (en) | 2019-04-29 |
| IL265192A (en) | 2019-05-30 |
| CA3036064A1 (en) | 2018-03-15 |
| EP3510023A1 (en) | 2019-07-17 |
| AU2017324445A1 (en) | 2019-04-11 |
| BR112019004517A2 (pt) | 2019-08-13 |
| US20190202805A1 (en) | 2019-07-04 |
| EP3510023B1 (en) | 2024-06-19 |
| JP2019532919A (ja) | 2019-11-14 |
| CN109983006B (zh) | 2022-02-25 |
| KR102587178B1 (ko) | 2023-10-06 |
| JP7079772B2 (ja) | 2022-06-02 |
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