ITMI20051943A1 - Processo di risoluzione anantiomerica di 2-aminometil-pirrolidine 1-sostitute per ammidazione in presenza di lipasi - Google Patents

Processo di risoluzione anantiomerica di 2-aminometil-pirrolidine 1-sostitute per ammidazione in presenza di lipasi

Info

Publication number
ITMI20051943A1
ITMI20051943A1 IT001943A ITMI20051943A ITMI20051943A1 IT MI20051943 A1 ITMI20051943 A1 IT MI20051943A1 IT 001943 A IT001943 A IT 001943A IT MI20051943 A ITMI20051943 A IT MI20051943A IT MI20051943 A1 ITMI20051943 A1 IT MI20051943A1
Authority
IT
Italy
Prior art keywords
anantiomeric
pyrrolidines
lipase
aminomethyl
substituted
Prior art date
Application number
IT001943A
Other languages
English (en)
Inventor
Giorgio Bertolini
Luigi Bogogna
Massimo Pregnolato
Marco Terreni
Francesco Velardi
Original Assignee
Procos Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procos Spa filed Critical Procos Spa
Priority to IT001943A priority Critical patent/ITMI20051943A1/it
Priority to EP06021182A priority patent/EP1775347A3/en
Priority to US11/548,804 priority patent/US20070105201A1/en
Publication of ITMI20051943A1 publication Critical patent/ITMI20051943A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
IT001943A 2005-10-14 2005-10-14 Processo di risoluzione anantiomerica di 2-aminometil-pirrolidine 1-sostitute per ammidazione in presenza di lipasi ITMI20051943A1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT001943A ITMI20051943A1 (it) 2005-10-14 2005-10-14 Processo di risoluzione anantiomerica di 2-aminometil-pirrolidine 1-sostitute per ammidazione in presenza di lipasi
EP06021182A EP1775347A3 (en) 2005-10-14 2006-10-09 A process for the enantiomeric resolution of 1-substituted 2-(aminomethyl)-pyrrolidines by amidation with lipases
US11/548,804 US20070105201A1 (en) 2005-10-14 2006-10-12 Process for the enantiomeric resolution of 1-substituted 2-(aminomethyl)-pyrrolidines by amidation in the presence of lipases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001943A ITMI20051943A1 (it) 2005-10-14 2005-10-14 Processo di risoluzione anantiomerica di 2-aminometil-pirrolidine 1-sostitute per ammidazione in presenza di lipasi

Publications (1)

Publication Number Publication Date
ITMI20051943A1 true ITMI20051943A1 (it) 2007-04-15

Family

ID=37685917

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001943A ITMI20051943A1 (it) 2005-10-14 2005-10-14 Processo di risoluzione anantiomerica di 2-aminometil-pirrolidine 1-sostitute per ammidazione in presenza di lipasi

Country Status (3)

Country Link
US (1) US20070105201A1 (it)
EP (1) EP1775347A3 (it)
IT (1) ITMI20051943A1 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103804265B (zh) * 2012-11-08 2018-08-07 江苏天士力帝益药业有限公司 一种舒必利或其光学异构体的合成及后处理方法
CN105837485A (zh) * 2015-01-16 2016-08-10 王志训 一种(S)-l-乙基-2-氨甲基吡咯烷的工业制造方法
SG11201707246YA (en) 2015-03-06 2017-10-30 Pharmakea Inc Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof
MX2019002615A (es) 2016-09-07 2019-10-15 Pharmakea Inc Formas cristalinas de un inhibidor tipo lisil oxidasa 2 y metodos de realizacion.
MX2019002612A (es) 2016-09-07 2019-08-21 Pharmakea Inc Usos de un inhibidor de lisil-oxidasa tipo 2.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1095415B (it) * 1978-02-16 1985-08-10 Ravizza Spa Processo per la produzione di una benzamide otticamente attiva,benzamide otticamente attiva cosi'ottenuta e composizioni
US5300660A (en) * 1986-05-22 1994-04-05 Astra Lakemedel Aktiebolag Efficient stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates thereto
EP0801683B1 (de) * 1995-02-03 2002-05-02 Basf Aktiengesellschaft Racematspaltung primärer und sekundärer heteroatomsubstituierter amine durch enzym-katalysierte acylierung

Also Published As

Publication number Publication date
US20070105201A1 (en) 2007-05-10
EP1775347A3 (en) 2007-07-25
EP1775347A2 (en) 2007-04-18

Similar Documents

Publication Publication Date Title
EP1956640A4 (en) LASER PROCESSING PROCEDURES
ITMI20050705A1 (it) Processo per la preparazione di dispersori di fluoropolimeri
ITMI20050817A1 (it) Processo di dealogenazione
ITMI20050247A1 (it) Processo per la preparazione di montelukast
ITMI20060082A1 (it) Processo per la preparazione di biodiesel
DE602006012689D1 (de) Überprüfungsverfahren
ITMI20051943A1 (it) Processo di risoluzione anantiomerica di 2-aminometil-pirrolidine 1-sostitute per ammidazione in presenza di lipasi
BRPI0717940A2 (pt) Produto e processo
BRPI0511701B1 (pt) processo de reduÇço direta
ITMI20050062A1 (it) Processo per la preparazione di fenolo
ITBO20060237A1 (it) Metodo e macchina per l'incarto di articoli.
ITBO20040561A1 (it) Macchina per la lavorazione di lamiere
DE602006018034D1 (de) Enzymherstellungsverfahren
ITBS20050119A1 (it) Macchina finitrice e metodo di finitura
ITMI20041941A1 (it) Processo per la preparazione di lisofosfatidilcoline
ITMI20061987A1 (it) Processo per la sintesi di arilossipropilammine ed eteroarilossipropilammine.
BRPI0610575A2 (pt) processo
ITMI20040452A1 (it) Processo per la preparazione di oxcarbazepina
ITFI20040063A1 (it) Processo per la purificazione di triptofano
ITMI20052341A1 (it) Processo per la preparazione di exemestano
ITMI20061573A1 (it) Processo per la preparazione di 1,1-dicloro-2-alchiletilene
ITMI20040133A1 (it) Processo per preparare fluoroalogenoeteri
ITMI20050818A1 (it) Processo di dealogenazione
ITMI20040132A1 (it) Processo per preparare fluoroalogenoeteri
FI20041609A0 (fi) Uudelleenkäyttömenetelmä