MA40057A - Traitement thérapeutique de maladie cutanée au moyen de micro-organismes cutanés commensaux recombinants - Google Patents

Traitement thérapeutique de maladie cutanée au moyen de micro-organismes cutanés commensaux recombinants

Info

Publication number
MA40057A
MA40057A MA040057A MA40057A MA40057A MA 40057 A MA40057 A MA 40057A MA 040057 A MA040057 A MA 040057A MA 40057 A MA40057 A MA 40057A MA 40057 A MA40057 A MA 40057A
Authority
MA
Morocco
Prior art keywords
skin
therapeutic
tratment
abnormal skin
microorganisms
Prior art date
Application number
MA040057A
Other languages
English (en)
French (fr)
Inventor
Azim Momin Munivar
Travis Michael Whitfill
Original Assignee
Azitra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Azitra filed Critical Azitra
Publication of MA40057A publication Critical patent/MA40057A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
MA040057A 2014-05-30 2015-05-28 Traitement thérapeutique de maladie cutanée au moyen de micro-organismes cutanés commensaux recombinants MA40057A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462005652P 2014-05-30 2014-05-30
US201462005558P 2014-05-30 2014-05-30

Publications (1)

Publication Number Publication Date
MA40057A true MA40057A (fr) 2015-12-03

Family

ID=54699800

Family Applications (1)

Application Number Title Priority Date Filing Date
MA040057A MA40057A (fr) 2014-05-30 2015-05-28 Traitement thérapeutique de maladie cutanée au moyen de micro-organismes cutanés commensaux recombinants

Country Status (7)

Country Link
US (3) US10702558B2 (enExample)
EP (2) EP4144756A1 (enExample)
JP (2) JP6810028B2 (enExample)
CA (1) CA2979079A1 (enExample)
ES (1) ES2929579T3 (enExample)
MA (1) MA40057A (enExample)
WO (1) WO2015184134A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4144756A1 (en) 2014-05-30 2023-03-08 Azitra, Inc. Therapeutic treatment of skin disease with recombinant commensal skin microorganisms
AU2017254684A1 (en) 2016-04-21 2018-12-06 Weiss Bioscience, Inc. Compositions and methods for treatment of skin disorders
JP2020527357A (ja) * 2017-06-16 2020-09-10 アジトラ インコーポレーテッド Lekti発現組換え微生物を用いたネザートン症候群の処置のための組成物および方法
EP3675884A4 (en) * 2017-08-31 2021-08-11 The Regents of the University of California MOLECULAR BACTERIOTHERAPY TO CONTROL ENZYMATIC ACTIVITY OF THE SKIN
WO2019050898A1 (en) * 2017-09-05 2019-03-14 Azitra Inc METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY SKIN DISEASE
JP7460531B2 (ja) 2017-12-05 2024-04-02 バイオピーエルエックス,インコーポレイティド 微生物感染を防ぐための方法および組成物
JP7121969B2 (ja) * 2018-02-23 2022-08-19 株式会社北里コーポレーション 培養液保護用液状物
AU2019249249B2 (en) 2018-04-05 2025-03-13 Azitra Inc Methods and compositions for treating skin disease with recombinant microorganisms
AU2019203692B2 (en) * 2018-08-30 2024-12-12 Kenvue Brands Llc Topical composition containing glycerin and yeast extract
US20210395775A1 (en) * 2018-09-26 2021-12-23 Krystal Biotech, Inc. Compositions and methods for the treatment of skin diseases
WO2020076770A1 (en) * 2018-10-08 2020-04-16 Yale University Selective binding and aggregation of human keratin in the skin barrier using human filaggrin subdomains sd67 and sd150
EP3880241A4 (en) * 2018-11-16 2022-08-17 Azitra, Inc. AUXOTROPHIC STRAINS OF STAPHYLOCOCCUS BACTERIA
CZ308231B6 (cs) * 2019-02-11 2020-03-11 BiomCare s.r.o. Kombinované několikastupňové mikrobiální přípravky a způsob jejich aplikace
CA3136115A1 (en) * 2019-04-05 2020-10-08 Azitra Inc Methods and compositions for treating atopic dermatitis with recombinant microorganisms
US20220362358A1 (en) * 2019-06-19 2022-11-17 Chan Zuckerberg Biohub, Inc. Bacteria-engineered to elicit antigen-specific t-cells
KR20220133262A (ko) * 2020-01-29 2022-10-04 더 잭슨 래보라토리 박테리아 혼합물
WO2022087065A1 (en) * 2020-10-21 2022-04-28 The Jackson Laboratory Antimicrobial biosensors
EP4274435A1 (en) * 2021-01-05 2023-11-15 Lactobio A/S Strains, compositions and methods of use

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0637384B2 (ja) * 1985-09-21 1994-05-18 株式会社資生堂 皮膚化粧料
US4659774A (en) 1985-11-01 1987-04-21 American Hoechst Corporation Support for solid-phase oligonucleotide synthesis
DE4221255C2 (de) 1992-06-26 1994-09-15 Lancaster Group Ag Phospholipide enthaltendes Kosmetikum
DE4221268C2 (de) 1992-06-26 1997-06-12 Lancaster Group Ag Verwendung eines Dermatikums zur Unterstützung des Sauerstofftransportes in der Haut
US20120295952A1 (en) * 2009-09-25 2012-11-22 Curna, Inc. Treatment of filaggrin (flg) related diseases by modulation of flg expression and activity
AU2010321784B2 (en) 2009-11-23 2014-04-24 Research Development Foundation Recombinant filaggrin polypeptides for cell importation
US20130078275A1 (en) * 2010-05-25 2013-03-28 The Board Of Trustees Of The University Of Illinois Novel systems, vectors, and methods for delivery of biomolecules to eukaryotic cells
US9234204B2 (en) * 2012-08-07 2016-01-12 TopGeniX, Inc. Topical composition comprising transformed bacteria expressing a compound of interest
KR101491240B1 (ko) 2013-03-15 2015-02-11 현대자동차주식회사 인비저블 슬라이딩 도어 링크 구조
EP4144756A1 (en) 2014-05-30 2023-03-08 Azitra, Inc. Therapeutic treatment of skin disease with recombinant commensal skin microorganisms

Also Published As

Publication number Publication date
US20210379120A1 (en) 2021-12-09
US20250009810A1 (en) 2025-01-09
JP2017518370A (ja) 2017-07-06
ES2929579T3 (es) 2022-11-30
EP3148569A1 (en) 2017-04-05
JP6810028B2 (ja) 2021-01-06
EP4144756A1 (en) 2023-03-08
WO2015184134A1 (en) 2015-12-03
CA2979079A1 (en) 2015-12-03
US10702558B2 (en) 2020-07-07
EP3148569B1 (en) 2022-07-06
EP3148569A4 (en) 2017-11-22
US12036248B2 (en) 2024-07-16
US20180161380A1 (en) 2018-06-14
JP2021038271A (ja) 2021-03-11

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