MA30620B1 - Carboxamides substitues - Google Patents

Carboxamides substitues

Info

Publication number
MA30620B1
MA30620B1 MA31553A MA31553A MA30620B1 MA 30620 B1 MA30620 B1 MA 30620B1 MA 31553 A MA31553 A MA 31553A MA 31553 A MA31553 A MA 31553A MA 30620 B1 MA30620 B1 MA 30620B1
Authority
MA
Morocco
Prior art keywords
substituted carboxamides
substituted
carboxamides
formula
pharmaceutically acceptable
Prior art date
Application number
MA31553A
Other languages
English (en)
French (fr)
Inventor
Ryan Thomas Backer
Matthew Joseph Fisher
Steven Lee Kuklish
Sean Patrick Hollinshead
Edward C R Smith
Kumiko Takeuchi
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA30620B1 publication Critical patent/MA30620B1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA31553A 2006-06-08 2009-01-06 Carboxamides substitues MA30620B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81183906P 2006-06-08 2006-06-08

Publications (1)

Publication Number Publication Date
MA30620B1 true MA30620B1 (fr) 2009-08-03

Family

ID=39673278

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31553A MA30620B1 (fr) 2006-06-08 2009-01-06 Carboxamides substitues

Country Status (30)

Country Link
US (1) US7960419B2 (https=)
EP (1) EP2076502B1 (https=)
JP (1) JP5108878B2 (https=)
KR (1) KR101051559B1 (https=)
CN (1) CN101466691B (https=)
AT (1) ATE509921T1 (https=)
AU (1) AU2007347428B2 (https=)
BR (1) BRPI0712862A2 (https=)
CA (1) CA2652074C (https=)
CR (1) CR10410A (https=)
CY (1) CY1111588T1 (https=)
DK (1) DK2076502T3 (https=)
EA (1) EA014233B1 (https=)
EC (1) ECSP088939A (https=)
ES (1) ES2362949T3 (https=)
HR (1) HRP20110436T1 (https=)
IL (1) IL195632A (https=)
MA (1) MA30620B1 (https=)
MX (1) MX2008015485A (https=)
MY (1) MY148084A (https=)
NO (1) NO341474B1 (https=)
NZ (1) NZ573352A (https=)
PL (1) PL2076502T3 (https=)
PT (1) PT2076502E (https=)
RS (1) RS51818B (https=)
SI (1) SI2076502T1 (https=)
TN (1) TNSN08506A1 (https=)
UA (1) UA95480C2 (https=)
WO (1) WO2008103185A2 (https=)
ZA (1) ZA200809111B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0804685D0 (en) 2008-03-13 2008-04-16 Univ Edinburgh Therapeutic compounds and their use
CA2720631C (en) 2008-04-04 2012-08-28 Eli Lilly And Company 3-indazolyl-4-pyridylisothiazoles
EP2443113A1 (en) * 2009-06-15 2012-04-25 The University Of Edinburgh Amido-isothiazole compounds and their use as inhibitors of 11beta-hsd1 for the treatment of metabolic syndrome and related disorders
EP2477983B1 (en) 2009-09-16 2015-04-15 The University Of Edinburgh (4-phenyl-piperidin-1-yl)-[5-1h-pyrazol-4yl)-thiophen-3-yl]-methanone compounds and their use
WO2011135276A1 (en) 2010-04-29 2011-11-03 The University Of Edinburgh 3, 3 -disubstituted- ( 8 - aza - bicyclo [3.2.1] oct- 8 - yl) -[5- (1h - pyrazol - 4 -yl) -thiophen-3 -yl] methanones as inhibitors of 11 (beta) -hsd1
ES2641469T3 (es) 2012-11-13 2017-11-10 Nissan Chemical Industries, Ltd. Compuesto de 2-piridona
WO2018054846A1 (de) 2016-09-23 2018-03-29 Bayer Aktiengesellschaft N3-cyclisch substituierte thienouracile und ihre verwendung
CN117567266B (zh) * 2023-11-07 2024-06-14 康龙化成手性医药技术(宁波)有限公司 一种制备2-甲基环丙羧酸的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL72091A0 (en) * 1983-06-20 1984-10-31 Lilly Co Eli N'-substituted(3-aryl 5-isothiazolyl)urea derivatives
DE4328425A1 (de) * 1993-08-24 1995-03-02 Basf Ag Acylamino-substituierte Isoxazol- bzw. Isothiazolderivate, Verfahren zu deren Herstellung und ihre Verwendung
DK124393D0 (da) * 1993-11-03 1993-11-03 Lundbeck & Co As H Compounds
DE19542372A1 (de) * 1995-11-14 1997-05-15 Bayer Ag Acylierte 5-Aminoisothiazole
UA60365C2 (uk) * 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
JP3411262B2 (ja) * 1999-08-20 2003-05-26 萬有製薬株式会社 新規スピロ化合物
EP1435948A1 (en) * 2001-08-06 2004-07-14 Pharmacia Italia S.p.A. Aminoisoxazole derivatives active as kinase inhibitors
WO2005030128A2 (en) * 2003-09-23 2005-04-07 Merck & Co., Inc. Pyrazole modulators of metabotropic glutamate receptors
WO2005113534A2 (en) * 2004-05-12 2005-12-01 Schering Corporation Cxcr1 and cxcr2 chemokine antagonists
JP2008513434A (ja) * 2004-09-23 2008-05-01 ファイザー・プロダクツ・インク トロンボポイエチン受容体アゴニスト

Also Published As

Publication number Publication date
UA95480C2 (uk) 2011-08-10
SI2076502T1 (sl) 2011-09-30
CA2652074C (en) 2013-08-06
EP2076502B1 (en) 2011-05-18
IL195632A (en) 2013-11-28
IL195632A0 (en) 2009-09-01
NO341474B1 (no) 2017-11-27
JP2009539874A (ja) 2009-11-19
KR20090008460A (ko) 2009-01-21
MX2008015485A (es) 2009-03-06
CA2652074A1 (en) 2008-08-28
CN101466691B (zh) 2011-07-27
WO2008103185A2 (en) 2008-08-28
PT2076502E (pt) 2011-06-07
MY148084A (en) 2013-02-28
HK1131984A1 (en) 2010-02-12
BRPI0712862A2 (pt) 2012-12-18
PL2076502T3 (pl) 2011-09-30
ZA200809111B (en) 2009-12-30
TNSN08506A1 (en) 2010-04-14
HRP20110436T1 (hr) 2011-08-31
NO20085028L (no) 2008-12-02
US7960419B2 (en) 2011-06-14
CN101466691A (zh) 2009-06-24
EP2076502A2 (en) 2009-07-08
RS51818B (sr) 2011-12-31
EA200870516A1 (ru) 2009-06-30
NZ573352A (en) 2011-10-28
DK2076502T3 (da) 2011-07-25
JP5108878B2 (ja) 2012-12-26
AU2007347428A1 (en) 2008-08-28
CR10410A (es) 2008-11-28
ES2362949T3 (es) 2011-07-15
KR101051559B1 (ko) 2011-07-22
CY1111588T1 (el) 2015-10-07
AU2007347428B2 (en) 2012-02-09
US20090182025A1 (en) 2009-07-16
ATE509921T1 (de) 2011-06-15
WO2008103185A3 (en) 2008-10-30
ECSP088939A (es) 2009-01-30
EA014233B1 (ru) 2010-10-29

Similar Documents

Publication Publication Date Title
MA30620B1 (fr) Carboxamides substitues
EA201001669A1 (ru) Замещенные пиримидин-5-карбоксамиды 281
EA200870193A1 (ru) Цитотоксические агенты, включающие новые производные томаймицина, и их терапевтическое применение
EA201071038A1 (ru) Производные 1-бензил-3-гидроксиметилиндазола и их применение для лечения заболеваний, основанных на экспрессии mcp-1, cx3cr1 и p40
CL2007000789A1 (es) Compuestos derivados de malonamida, inhibidores de la gamma-secretasa; proceso de preparacion; composicion farmaceutica; y su uso en el tratamiento de la enfermedad de alzheimer.
MY146662A (en) Novel n-(8-heteroaryltetrahydronaphtalene-2yl) or n-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain
TW201000473A (en) Benzene or thiophene derivative and use thereof as VAP-1 inhibitor
EA201270221A1 (ru) Лечение болезни крона с применением лаквинимода
EA200971107A1 (ru) Катехоламиновые производные, полезные для лечения болезни паркинсона
IL192100A0 (en) Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
ATE554084T1 (de) N-hydroxyacrylamidverbindungen
MA32544B1 (fr) Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
CL2007000918A1 (es) Compuestos derivados de enfumafungina, inhibidores de (1,3)-beta-d-glucanosintetasa; composicion farmaceutica; y uso para tratar una infeccion fungica.
DE602005013793D1 (de) Thiazolderivate mit vap-1-hemmender wirkung
MX2009011900A (es) Curacion de herida diabetica.
EA201000391A1 (ru) Соединение, представляющее собой ингибитор гликогенфосфорилазы, и его фармацевтическая композиция
MX2009005798A (es) Recuperacion de apoplejia.
UA112418C2 (uk) Терапевтичний болезаспокійливий засіб
EA201000392A1 (ru) Соединение, представляющее собой ингибитор гликогенфосфорилазы, и его фармацевтическая композиция
ATE412636T1 (de) Piperazinylpyridinderivate als mittel gegen adipositas
EA200870287A1 (ru) Амидные производные в качестве лигандов ионных каналов и фармацевтические композиции и способы их применения
DOP2008000064A (es) Carboxamidas sustituidas.
ATE468852T1 (de) Lofexidine zur intraspinalen anwendung
UA103767C2 (ru) Карбоксамидные соединения для лечения метаболических расстройств
HK1152939A1 (en) Carboxamide compounds for the treatment of metabolic disorders