PL2076502T3 - Podstawione karboksyamidy jako antagoniści receptorów metabotropowych grupy I - Google Patents
Podstawione karboksyamidy jako antagoniści receptorów metabotropowych grupy IInfo
- Publication number
- PL2076502T3 PL2076502T3 PL07873705T PL07873705T PL2076502T3 PL 2076502 T3 PL2076502 T3 PL 2076502T3 PL 07873705 T PL07873705 T PL 07873705T PL 07873705 T PL07873705 T PL 07873705T PL 2076502 T3 PL2076502 T3 PL 2076502T3
- Authority
- PL
- Poland
- Prior art keywords
- group
- receptor antagonists
- metabotropic receptor
- substituted carboxamides
- substituted
- Prior art date
Links
- 150000003857 carboxamides Chemical class 0.000 title 1
- 239000003512 metabotropic receptor antagonist Substances 0.000 title 1
- -1 carboxamide compound Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81183906P | 2006-06-08 | 2006-06-08 | |
| EP07873705A EP2076502B1 (en) | 2006-06-08 | 2007-06-07 | Substituted carboxamides as group i metabotropic receptor antagonists |
| PCT/US2007/070572 WO2008103185A2 (en) | 2006-06-08 | 2007-06-07 | Substituted carboxamides as group i metabotropic receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2076502T3 true PL2076502T3 (pl) | 2011-09-30 |
Family
ID=39673278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07873705T PL2076502T3 (pl) | 2006-06-08 | 2007-06-07 | Podstawione karboksyamidy jako antagoniści receptorów metabotropowych grupy I |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7960419B2 (https=) |
| EP (1) | EP2076502B1 (https=) |
| JP (1) | JP5108878B2 (https=) |
| KR (1) | KR101051559B1 (https=) |
| CN (1) | CN101466691B (https=) |
| AT (1) | ATE509921T1 (https=) |
| AU (1) | AU2007347428B2 (https=) |
| BR (1) | BRPI0712862A2 (https=) |
| CA (1) | CA2652074C (https=) |
| CR (1) | CR10410A (https=) |
| CY (1) | CY1111588T1 (https=) |
| DK (1) | DK2076502T3 (https=) |
| EA (1) | EA014233B1 (https=) |
| EC (1) | ECSP088939A (https=) |
| ES (1) | ES2362949T3 (https=) |
| HR (1) | HRP20110436T1 (https=) |
| IL (1) | IL195632A (https=) |
| MA (1) | MA30620B1 (https=) |
| MX (1) | MX2008015485A (https=) |
| MY (1) | MY148084A (https=) |
| NO (1) | NO341474B1 (https=) |
| NZ (1) | NZ573352A (https=) |
| PL (1) | PL2076502T3 (https=) |
| PT (1) | PT2076502E (https=) |
| RS (1) | RS51818B (https=) |
| SI (1) | SI2076502T1 (https=) |
| TN (1) | TNSN08506A1 (https=) |
| UA (1) | UA95480C2 (https=) |
| WO (1) | WO2008103185A2 (https=) |
| ZA (1) | ZA200809111B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0804685D0 (en) | 2008-03-13 | 2008-04-16 | Univ Edinburgh | Therapeutic compounds and their use |
| CA2720631C (en) | 2008-04-04 | 2012-08-28 | Eli Lilly And Company | 3-indazolyl-4-pyridylisothiazoles |
| EP2443113A1 (en) * | 2009-06-15 | 2012-04-25 | The University Of Edinburgh | Amido-isothiazole compounds and their use as inhibitors of 11beta-hsd1 for the treatment of metabolic syndrome and related disorders |
| EP2477983B1 (en) | 2009-09-16 | 2015-04-15 | The University Of Edinburgh | (4-phenyl-piperidin-1-yl)-[5-1h-pyrazol-4yl)-thiophen-3-yl]-methanone compounds and their use |
| WO2011135276A1 (en) | 2010-04-29 | 2011-11-03 | The University Of Edinburgh | 3, 3 -disubstituted- ( 8 - aza - bicyclo [3.2.1] oct- 8 - yl) -[5- (1h - pyrazol - 4 -yl) -thiophen-3 -yl] methanones as inhibitors of 11 (beta) -hsd1 |
| ES2641469T3 (es) | 2012-11-13 | 2017-11-10 | Nissan Chemical Industries, Ltd. | Compuesto de 2-piridona |
| WO2018054846A1 (de) | 2016-09-23 | 2018-03-29 | Bayer Aktiengesellschaft | N3-cyclisch substituierte thienouracile und ihre verwendung |
| CN117567266B (zh) * | 2023-11-07 | 2024-06-14 | 康龙化成手性医药技术(宁波)有限公司 | 一种制备2-甲基环丙羧酸的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL72091A0 (en) * | 1983-06-20 | 1984-10-31 | Lilly Co Eli | N'-substituted(3-aryl 5-isothiazolyl)urea derivatives |
| DE4328425A1 (de) * | 1993-08-24 | 1995-03-02 | Basf Ag | Acylamino-substituierte Isoxazol- bzw. Isothiazolderivate, Verfahren zu deren Herstellung und ihre Verwendung |
| DK124393D0 (da) * | 1993-11-03 | 1993-11-03 | Lundbeck & Co As H | Compounds |
| DE19542372A1 (de) * | 1995-11-14 | 1997-05-15 | Bayer Ag | Acylierte 5-Aminoisothiazole |
| UA60365C2 (uk) * | 1998-06-04 | 2003-10-15 | Пфайзер Продактс Інк. | Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця |
| JP3411262B2 (ja) * | 1999-08-20 | 2003-05-26 | 萬有製薬株式会社 | 新規スピロ化合物 |
| EP1435948A1 (en) * | 2001-08-06 | 2004-07-14 | Pharmacia Italia S.p.A. | Aminoisoxazole derivatives active as kinase inhibitors |
| WO2005030128A2 (en) * | 2003-09-23 | 2005-04-07 | Merck & Co., Inc. | Pyrazole modulators of metabotropic glutamate receptors |
| WO2005113534A2 (en) * | 2004-05-12 | 2005-12-01 | Schering Corporation | Cxcr1 and cxcr2 chemokine antagonists |
| JP2008513434A (ja) * | 2004-09-23 | 2008-05-01 | ファイザー・プロダクツ・インク | トロンボポイエチン受容体アゴニスト |
-
2007
- 2007-06-07 UA UAA200813907A patent/UA95480C2/uk unknown
- 2007-06-07 NZ NZ573352A patent/NZ573352A/en not_active IP Right Cessation
- 2007-06-07 WO PCT/US2007/070572 patent/WO2008103185A2/en not_active Ceased
- 2007-06-07 AU AU2007347428A patent/AU2007347428B2/en not_active Ceased
- 2007-06-07 JP JP2009514523A patent/JP5108878B2/ja not_active Expired - Fee Related
- 2007-06-07 SI SI200730695T patent/SI2076502T1/sl unknown
- 2007-06-07 RS RS20110336A patent/RS51818B/sr unknown
- 2007-06-07 CA CA2652074A patent/CA2652074C/en not_active Expired - Fee Related
- 2007-06-07 AT AT07873705T patent/ATE509921T1/de active
- 2007-06-07 CN CN2007800211890A patent/CN101466691B/zh not_active Expired - Fee Related
- 2007-06-07 HR HR20110436T patent/HRP20110436T1/hr unknown
- 2007-06-07 MY MYPI20084973A patent/MY148084A/en unknown
- 2007-06-07 KR KR1020087029772A patent/KR101051559B1/ko not_active Expired - Fee Related
- 2007-06-07 EA EA200870516A patent/EA014233B1/ru not_active IP Right Cessation
- 2007-06-07 EP EP07873705A patent/EP2076502B1/en active Active
- 2007-06-07 DK DK07873705.3T patent/DK2076502T3/da active
- 2007-06-07 PT PT07873705T patent/PT2076502E/pt unknown
- 2007-06-07 BR BRPI0712862-2A patent/BRPI0712862A2/pt not_active IP Right Cessation
- 2007-06-07 US US12/300,415 patent/US7960419B2/en active Active
- 2007-06-07 ES ES07873705T patent/ES2362949T3/es active Active
- 2007-06-07 MX MX2008015485A patent/MX2008015485A/es active IP Right Grant
- 2007-06-07 PL PL07873705T patent/PL2076502T3/pl unknown
- 2007-10-29 CR CR10410A patent/CR10410A/es unknown
-
2008
- 2008-10-23 ZA ZA200809111A patent/ZA200809111B/xx unknown
- 2008-12-01 IL IL195632A patent/IL195632A/en not_active IP Right Cessation
- 2008-12-02 NO NO20085028A patent/NO341474B1/no not_active IP Right Cessation
- 2008-12-03 EC EC2008008939A patent/ECSP088939A/es unknown
- 2008-12-05 TN TNP2008000506A patent/TNSN08506A1/en unknown
-
2009
- 2009-01-06 MA MA31553A patent/MA30620B1/fr unknown
-
2011
- 2011-06-24 CY CY20111100600T patent/CY1111588T1/el unknown
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