CY1111588T1 - Υποκατεστημενα καρβοξαμιδια ως ανταγωνιστες μεταβολοτροπου υποδοχεα ομαδας ι - Google Patents

Υποκατεστημενα καρβοξαμιδια ως ανταγωνιστες μεταβολοτροπου υποδοχεα ομαδας ι

Info

Publication number
CY1111588T1
CY1111588T1 CY20111100600T CY111100600T CY1111588T1 CY 1111588 T1 CY1111588 T1 CY 1111588T1 CY 20111100600 T CY20111100600 T CY 20111100600T CY 111100600 T CY111100600 T CY 111100600T CY 1111588 T1 CY1111588 T1 CY 1111588T1
Authority
CY
Cyprus
Prior art keywords
concentrators
converter
substituted carboxamides
substituted
carboxamides
Prior art date
Application number
CY20111100600T
Other languages
English (en)
Inventor
Ryan Thomas Backer
Matthew Joseph Fisher
Steven Lee Kuklish
Sean Patrick Hollinshead
Edward C R Smith
Kumiko Takeuchi
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of CY1111588T1 publication Critical patent/CY1111588T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Η παρούσα αίτηση αναφέρεται σε μια ένωση υποκατεστημένου καρβοξαμιδίου του τύπου Ι, ή σε ένα φαρμακευτικώς αποδεκτό άλας αυτής, όπως ορίζεται εδώ, σε μια φαρμακευτική σύνθεση αυτής, και στη χρησιμοποίησή της στη θεραπεία του πόνου.
CY20111100600T 2006-06-08 2011-06-24 Υποκατεστημενα καρβοξαμιδια ως ανταγωνιστες μεταβολοτροπου υποδοχεα ομαδας ι CY1111588T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81183906P 2006-06-08 2006-06-08
EP07873705A EP2076502B1 (en) 2006-06-08 2007-06-07 Substituted carboxamides as group i metabotropic receptor antagonists

Publications (1)

Publication Number Publication Date
CY1111588T1 true CY1111588T1 (el) 2015-10-07

Family

ID=39673278

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100600T CY1111588T1 (el) 2006-06-08 2011-06-24 Υποκατεστημενα καρβοξαμιδια ως ανταγωνιστες μεταβολοτροπου υποδοχεα ομαδας ι

Country Status (30)

Country Link
US (1) US7960419B2 (el)
EP (1) EP2076502B1 (el)
JP (1) JP5108878B2 (el)
KR (1) KR101051559B1 (el)
CN (1) CN101466691B (el)
AT (1) ATE509921T1 (el)
AU (1) AU2007347428B2 (el)
BR (1) BRPI0712862A2 (el)
CA (1) CA2652074C (el)
CR (1) CR10410A (el)
CY (1) CY1111588T1 (el)
DK (1) DK2076502T3 (el)
EA (1) EA014233B1 (el)
EC (1) ECSP088939A (el)
ES (1) ES2362949T3 (el)
HR (1) HRP20110436T1 (el)
IL (1) IL195632A (el)
MA (1) MA30620B1 (el)
MX (1) MX2008015485A (el)
MY (1) MY148084A (el)
NO (1) NO341474B1 (el)
NZ (1) NZ573352A (el)
PL (1) PL2076502T3 (el)
PT (1) PT2076502E (el)
RS (1) RS51818B (el)
SI (1) SI2076502T1 (el)
TN (1) TNSN08506A1 (el)
UA (1) UA95480C2 (el)
WO (1) WO2008103185A2 (el)
ZA (1) ZA200809111B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0804685D0 (en) 2008-03-13 2008-04-16 Univ Edinburgh Therapeutic compounds and their use
PL2276759T3 (pl) 2008-04-04 2012-03-30 Lilly Co Eli 3-indazolilo-4-pirydyloizotiazole
US20120095046A1 (en) * 2009-06-15 2012-04-19 The University Of Edinburgh Amido-Isothiazole Compounds and Their Use as Inhibitors of 11Beta-HSD1 for the Treatment of Metabolic Syndrome and Related Disorders
ES2540547T3 (es) 2009-09-16 2015-07-10 The University Of Edinburgh Compuestos de (4-fenil-piperidin-1-il)-[5-(1H-pirazol-4-il)-tiofen-3-il]-metanona y su uso
MX344142B (es) 2010-04-29 2016-12-07 The Univ Of Edinburgh (8-aza-biciclico[3.2.1]oct-8-il)-[5-(1h-pirazol-4-il)-tiofen-3-il ]-metanonas 3, 3-disubstituidas como inhibidores de 1(beta)-hsd1.
DK2921489T3 (en) 2012-11-13 2017-10-16 Nissan Chemical Ind Ltd 2-pyridone-RELATED
CA3037642A1 (en) 2016-09-23 2018-03-29 Bayer Aktiengesellschaft N 3 -cyclically substituted thienouraciles and use thereof
CN117567266B (zh) * 2023-11-07 2024-06-14 康龙化成手性医药技术(宁波)有限公司 一种制备2-甲基环丙羧酸的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL72091A0 (en) * 1983-06-20 1984-10-31 Lilly Co Eli N'-substituted(3-aryl 5-isothiazolyl)urea derivatives
DE4328425A1 (de) * 1993-08-24 1995-03-02 Basf Ag Acylamino-substituierte Isoxazol- bzw. Isothiazolderivate, Verfahren zu deren Herstellung und ihre Verwendung
DK124393D0 (da) * 1993-11-03 1993-11-03 Lundbeck & Co As H Compounds
DE19542372A1 (de) * 1995-11-14 1997-05-15 Bayer Ag Acylierte 5-Aminoisothiazole
UA60365C2 (uk) * 1998-06-04 2003-10-15 Пфайзер Продактс Інк. Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
JP3411262B2 (ja) * 1999-08-20 2003-05-26 萬有製薬株式会社 新規スピロ化合物
WO2003013517A1 (en) * 2001-08-06 2003-02-20 Pharmacia Italia S.P.A. Aminoisoxazole derivatives active as kinase inhibitors
JP2007506741A (ja) * 2003-09-23 2007-03-22 メルク　エンド　カムパニー　インコーポレーテッド 向代謝性グルタミン酸受容体のピラゾール系調節剤
EP1745032B1 (en) * 2004-05-12 2013-07-31 Merck Sharp & Dohme Corp. CXCR1 and CXCR2 chemokine antagonists
CA2581657A1 (en) * 2004-09-23 2006-03-30 Pfizer Products Inc. Thrombopoietin receptor agonists

Also Published As

Publication number Publication date
HRP20110436T1 (hr) 2011-08-31
EP2076502B1 (en) 2011-05-18
CN101466691B (zh) 2011-07-27
US7960419B2 (en) 2011-06-14
RS51818B (sr) 2011-12-31
AU2007347428A1 (en) 2008-08-28
EA200870516A1 (ru) 2009-06-30
MY148084A (en) 2013-02-28
US20090182025A1 (en) 2009-07-16
NO20085028L (no) 2008-12-02
IL195632A0 (en) 2009-09-01
CR10410A (es) 2008-11-28
PL2076502T3 (pl) 2011-09-30
CN101466691A (zh) 2009-06-24
UA95480C2 (uk) 2011-08-10
PT2076502E (pt) 2011-06-07
AU2007347428B2 (en) 2012-02-09
MA30620B1 (fr) 2009-08-03
EA014233B1 (ru) 2010-10-29
JP5108878B2 (ja) 2012-12-26
NO341474B1 (no) 2017-11-27
JP2009539874A (ja) 2009-11-19
BRPI0712862A2 (pt) 2012-12-18
NZ573352A (en) 2011-10-28
HK1131984A1 (en) 2010-02-12
KR20090008460A (ko) 2009-01-21
WO2008103185A3 (en) 2008-10-30
CA2652074A1 (en) 2008-08-28
KR101051559B1 (ko) 2011-07-22
MX2008015485A (es) 2009-03-06
EP2076502A2 (en) 2009-07-08
SI2076502T1 (sl) 2011-09-30
ECSP088939A (es) 2009-01-30
DK2076502T3 (da) 2011-07-25
IL195632A (en) 2013-11-28
WO2008103185A2 (en) 2008-08-28
ZA200809111B (en) 2009-12-30
CA2652074C (en) 2013-08-06
ES2362949T3 (es) 2011-07-15
ATE509921T1 (de) 2011-06-15
TNSN08506A1 (en) 2010-04-14

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