MA30090B1 - Utilisation d'un antagoniste de CB1 pour le traitement des effets secondaires et des symptômes négatifs de la schizophrénie - Google Patents
Utilisation d'un antagoniste de CB1 pour le traitement des effets secondaires et des symptômes négatifs de la schizophrénieInfo
- Publication number
- MA30090B1 MA30090B1 MA31081A MA31081A MA30090B1 MA 30090 B1 MA30090 B1 MA 30090B1 MA 31081 A MA31081 A MA 31081A MA 31081 A MA31081 A MA 31081A MA 30090 B1 MA30090 B1 MA 30090B1
- Authority
- MA
- Morocco
- Prior art keywords
- schizophrenia
- treatment
- negative symptoms
- antagonist
- combination
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La présente invention divulgue et revendique une méthode de traitement de déficits cognitifs chez un patient atteint de la schizophrénie par l'administration audit patient d'une quantité thérapeutiquement efficace d'un antagoniste du récepteur CB1 comme décrit dans la présente. Dans un autre aspect, cette invention divulgue et revendique également une combinaison d'un ou de plusieurs antagonistes du récepteur CB1 et d'un ou plusieurs agents antipsychotiques utiles dans le traitement de troubles psychiatriques. La combinaison de cette invention donne des résultats synergiques en ce que la combinaison améliore les symptômes positifs et négatifs de la schizophrénie, la prise de poids et la catalepsie.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74843405P | 2005-12-08 | 2005-12-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA30090B1 true MA30090B1 (fr) | 2008-12-01 |
Family
ID=37964962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA31081A MA30090B1 (fr) | 2005-12-08 | 2008-06-26 | Utilisation d'un antagoniste de CB1 pour le traitement des effets secondaires et des symptômes négatifs de la schizophrénie |
Country Status (23)
Country | Link |
---|---|
US (1) | US20080221078A1 (fr) |
EP (1) | EP1962834A2 (fr) |
JP (1) | JP2009518423A (fr) |
KR (1) | KR20080073737A (fr) |
CN (1) | CN101321523A (fr) |
AR (1) | AR056846A1 (fr) |
AU (1) | AU2006321907A1 (fr) |
BR (1) | BRPI0619541A2 (fr) |
CA (1) | CA2632673A1 (fr) |
CR (1) | CR9957A (fr) |
DO (1) | DOP2006000273A (fr) |
EC (1) | ECSP088505A (fr) |
IL (1) | IL191888A0 (fr) |
MA (1) | MA30090B1 (fr) |
NO (1) | NO20082923L (fr) |
PE (1) | PE20071092A1 (fr) |
RU (1) | RU2008127491A (fr) |
SV (1) | SV2008002929A (fr) |
TN (1) | TNSN08205A1 (fr) |
TW (1) | TW200803839A (fr) |
UY (1) | UY29995A1 (fr) |
WO (1) | WO2007067617A2 (fr) |
ZA (1) | ZA200803924B (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200630337A (en) | 2004-10-14 | 2006-09-01 | Euro Celtique Sa | Piperidinyl compounds and the use thereof |
US7906652B2 (en) | 2005-11-28 | 2011-03-15 | Merck Sharp & Dohme Corp. | Heterocycle-substituted 3-alkyl azetidine derivatives |
WO2007110449A1 (fr) * | 2006-03-29 | 2007-10-04 | Euro-Celtique S.A. | Composés de benzènesulfonamide et utilisation de ceux-ci |
US8937181B2 (en) | 2006-04-13 | 2015-01-20 | Purdue Pharma L.P. | Benzenesulfonamide compounds and the use thereof |
TW200815353A (en) | 2006-04-13 | 2008-04-01 | Euro Celtique Sa | Benzenesulfonamide compounds and their use |
US8399486B2 (en) | 2007-04-09 | 2013-03-19 | Purdue Pharma L.P. | Benzenesulfonyl compounds and the use thereof |
WO2009040659A2 (fr) | 2007-09-28 | 2009-04-02 | Purdue Pharma L.P. | Composés benzènesulfonamides et leurs utilisations |
EP2205083B1 (fr) * | 2007-10-04 | 2013-07-17 | Merck Sharp & Dohme Corp. | Dérivé d'arylsulfone substituée comme bloqueurs des canaux calciques |
AU2008351943B2 (en) | 2007-12-18 | 2013-12-19 | Sanofi-Aventis | Azetidine derivatives, their preparation and their application in therapy |
FR2925051B1 (fr) * | 2007-12-18 | 2010-05-21 | Sanofi Aventis | Derives d'azetidines,leur preparation et leur application en therapeutique |
GB2456183A (en) * | 2008-01-04 | 2009-07-08 | Gw Pharma Ltd | Anti-psychotic composition comprising cannabinoids and anti-psychotic medicament |
WO2010079241A1 (fr) | 2009-01-12 | 2010-07-15 | Fundacion Hospital Nacional De Paraplejicos Para La Investigacion Y La Integracion | Utilisation d'antagonistes et/ou d'agonistes inverses des récepteurs cb1 pour la préparation de médicaments qui augmentent l'excitabilité des motoneurones |
CN112961149A (zh) | 2014-08-11 | 2021-06-15 | 安吉恩生物医药公司 | 细胞色素p450抑制剂及其用途 |
AU2015374231B2 (en) | 2014-12-31 | 2020-07-23 | Angion Biomedica Corp. | Methods and agents for treating disease |
IL311081A (en) | 2016-08-24 | 2024-04-01 | Prilenia Neurotherapeutics Ltd | Use of pyridofidine to treat functional decline |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6355631B1 (en) * | 2000-03-03 | 2002-03-12 | Aventis Pharma S.A. | Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and their preparation |
US6566356B2 (en) * | 2000-03-03 | 2003-05-20 | Aventis Pharma S.A. | Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation |
US6479479B2 (en) * | 2000-03-03 | 2002-11-12 | Aventis Pharma S.A. | Azetidine derivatives, their preparation and pharmaceutical compositions containing them |
CN1802351A (zh) * | 2003-06-11 | 2006-07-12 | 麦克公司 | 被取代的3-烷基和3-链烯基氮杂环丁烷衍生物 |
WO2005020992A1 (fr) * | 2003-09-02 | 2005-03-10 | Solvay Pharmaceuticals Gmbh | Nouvelles utilisations medicales d'antagonistes selectifs du recepteur cb1 |
WO2006017892A1 (fr) * | 2004-08-16 | 2006-02-23 | Northern Sydney And Central Coast Area Health Service | Procedes d'amelioration du fonctionnement cognitif |
FR2882931B1 (fr) * | 2005-03-14 | 2007-05-18 | Sanofi Aventis Sa | Compositions pharmaceutiques contenant en association un compose antagoniste des recepteurs aux cannabinoidess et un agent antipsychotique |
-
2006
- 2006-12-06 PE PE2006001558A patent/PE20071092A1/es not_active Application Discontinuation
- 2006-12-06 DO DO2006000273A patent/DOP2006000273A/es unknown
- 2006-12-07 BR BRPI0619541-5A patent/BRPI0619541A2/pt not_active IP Right Cessation
- 2006-12-07 EP EP06839095A patent/EP1962834A2/fr not_active Ceased
- 2006-12-07 RU RU2008127491/15A patent/RU2008127491A/ru not_active Application Discontinuation
- 2006-12-07 KR KR1020087013697A patent/KR20080073737A/ko not_active Application Discontinuation
- 2006-12-07 JP JP2008544469A patent/JP2009518423A/ja not_active Abandoned
- 2006-12-07 CA CA002632673A patent/CA2632673A1/fr not_active Abandoned
- 2006-12-07 WO PCT/US2006/046547 patent/WO2007067617A2/fr active Application Filing
- 2006-12-07 AU AU2006321907A patent/AU2006321907A1/en not_active Abandoned
- 2006-12-07 CN CNA2006800454370A patent/CN101321523A/zh active Pending
- 2006-12-07 AR ARP060105411A patent/AR056846A1/es not_active Application Discontinuation
- 2006-12-08 TW TW095145876A patent/TW200803839A/zh unknown
- 2006-12-08 UY UY29995A patent/UY29995A1/es unknown
-
2008
- 2008-05-07 CR CR9957A patent/CR9957A/es not_active Application Discontinuation
- 2008-05-08 ZA ZA200803924A patent/ZA200803924B/xx unknown
- 2008-05-08 TN TNP2008000205A patent/TNSN08205A1/en unknown
- 2008-05-22 US US12/125,285 patent/US20080221078A1/en not_active Abandoned
- 2008-06-02 IL IL191888A patent/IL191888A0/en unknown
- 2008-06-06 EC EC2008008505A patent/ECSP088505A/es unknown
- 2008-06-06 SV SV2008002929A patent/SV2008002929A/es not_active Application Discontinuation
- 2008-06-25 NO NO20082923A patent/NO20082923L/no not_active Application Discontinuation
- 2008-06-26 MA MA31081A patent/MA30090B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
NO20082923L (no) | 2008-09-02 |
RU2008127491A (ru) | 2010-01-20 |
TNSN08205A1 (en) | 2009-10-30 |
BRPI0619541A2 (pt) | 2011-10-04 |
CR9957A (es) | 2008-09-22 |
ECSP088505A (es) | 2008-08-29 |
AR056846A1 (es) | 2007-10-24 |
SV2008002929A (es) | 2009-12-02 |
EP1962834A2 (fr) | 2008-09-03 |
IL191888A0 (en) | 2009-08-03 |
DOP2006000273A (es) | 2007-10-15 |
PE20071092A1 (es) | 2007-12-10 |
CN101321523A (zh) | 2008-12-10 |
UY29995A1 (es) | 2007-07-31 |
WO2007067617A3 (fr) | 2007-11-01 |
AU2006321907A1 (en) | 2007-06-14 |
KR20080073737A (ko) | 2008-08-11 |
US20080221078A1 (en) | 2008-09-11 |
ZA200803924B (en) | 2009-10-28 |
TW200803839A (en) | 2008-01-16 |
WO2007067617A2 (fr) | 2007-06-14 |
JP2009518423A (ja) | 2009-05-07 |
CA2632673A1 (fr) | 2007-06-14 |
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