MA29811B1 - [1,3,4]-thiadiazol-2-yl-amides d'acide (aryle bicyclique)-sulfonique procedes pour leur preparation et leur utilisation en tant que produits pharmaceutiques - Google Patents
[1,3,4]-thiadiazol-2-yl-amides d'acide (aryle bicyclique)-sulfonique procedes pour leur preparation et leur utilisation en tant que produits pharmaceutiquesInfo
- Publication number
- MA29811B1 MA29811B1 MA30789A MA30789A MA29811B1 MA 29811 B1 MA29811 B1 MA 29811B1 MA 30789 A MA30789 A MA 30789A MA 30789 A MA30789 A MA 30789A MA 29811 B1 MA29811 B1 MA 29811B1
- Authority
- MA
- Morocco
- Prior art keywords
- disorders
- thiadiazol
- processes
- preparation
- sulfonic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
L'INVENTION CONCERNE DES [1,3,4]THIADIAZOL-2-YL-AMIDES BICYCLIQUES DE L'ACIDE ARYL-SULFONIQUE DE FORMULE (I), DANS LAQUELLE LES RADICAUX SONT TELS QUE DÉFINIS, AINSI QUE LEURS SELS PHYSIOLOGIQUEMENT ACCEPTABLES ET DÉRIVÉS PHYSIOLOGIQUEMENT FONCTIONNELS QUI PRÉSENTENT UNE ACTIVITÉ AGONISTE PPAR DELTA, ALPHA, ET GAMMA. CETTE INVENTION CONCERNE ÉGALEMENT DES PROCÉDÉS DE PRÉPARATION DE CES COMPOSÉS. LESDITS COMPOSÉS PEUVENT SERVIR À TRAITER ET/OU PRÉVENIR DES TROUBLES DU MÉTABOLISME DES ACIDES GRAS, DES TROUBLES DE L'UTILISATION DU GLUCOSE, DES TROUBLES IMPLIQUANT LA RÉSISTANCE À L'INSULINE, AINSI QUE DES TROUBLES DE DÉMYÉLINISATION ET D'AUTRES TROUBLES NEURODÉGÉNÉRATIFS DU SYSTÈME NERVEUX CENTRAL ET PÉRIPHÉRIQUE
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05021785 | 2005-10-06 | ||
PCT/EP2006/009300 WO2007039174A2 (fr) | 2005-10-06 | 2006-09-26 | [1,3,4]-thiadiazol-2-yl-amides bicycliques de l'acide aryl-sulfonique, leurs procedes de preparation, et leur utilisation en tant que substances pharmaceutiques |
Publications (1)
Publication Number | Publication Date |
---|---|
MA29811B1 true MA29811B1 (fr) | 2008-09-01 |
Family
ID=45219048
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA30789A MA29811B1 (fr) | 2005-10-06 | 2008-03-31 | [1,3,4]-thiadiazol-2-yl-amides d'acide (aryle bicyclique)-sulfonique procedes pour leur preparation et leur utilisation en tant que produits pharmaceutiques |
Country Status (19)
Country | Link |
---|---|
US (2) | US7612104B2 (fr) |
EP (1) | EP1937675B1 (fr) |
JP (1) | JP2009510146A (fr) |
KR (1) | KR20080050607A (fr) |
CN (1) | CN101282969A (fr) |
AR (1) | AR056563A1 (fr) |
AT (1) | ATE513829T1 (fr) |
AU (1) | AU2006299088A1 (fr) |
BR (1) | BRPI0616872A2 (fr) |
CA (1) | CA2624329A1 (fr) |
IL (1) | IL190459A0 (fr) |
MA (1) | MA29811B1 (fr) |
NO (1) | NO20081676L (fr) |
NZ (1) | NZ567204A (fr) |
RU (1) | RU2008113209A (fr) |
TW (1) | TW200811120A (fr) |
UY (1) | UY29848A1 (fr) |
WO (1) | WO2007039174A2 (fr) |
ZA (1) | ZA200801989B (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201040153A (en) | 2009-02-13 | 2010-11-16 | Sanofi Aventis | Novel substituted tetrahydronaphthalenes, process for preparation thereof and use thereof as medicaments |
UY32442A (es) * | 2009-02-13 | 2010-09-30 | Sanofi Aventis | Nuevos indanos sustituidos, procesos para su preparacion y uso de los mismos como un medicamento |
GB201810581D0 (en) | 2018-06-28 | 2018-08-15 | Ctxt Pty Ltd | Compounds |
EP3986890B1 (fr) | 2019-06-18 | 2023-11-15 | Pfizer Inc. | Dérivés de benzisoxazole sulfonamide |
CN116041230B (zh) * | 2023-01-08 | 2024-03-19 | 中国海洋大学 | 一种nlrp3炎症小体抑制剂及其制备方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670282B2 (de) * | 1967-10-24 | 1977-02-24 | Antidiabetisch wirksame hydrindensulfonylamino-pyrimidine sowie verfahren zu deren herstellung | |
DE2533605A1 (de) * | 1975-07-26 | 1977-02-03 | Bayer Ag | Antiparasitenmittel |
US5097669A (en) | 1991-02-11 | 1992-03-24 | Westinghouse Electric Corp. | Control of hydrogen cooler employed in power generators |
BR0110428A (pt) * | 2000-04-28 | 2003-06-17 | Sankyo Co | Composto ou um seu sal farmacologicamente aceitável, composição farmacêutica, usos de um composto ou um seu sal farmacologicamente aceitável, de um modulador de ppar gama e de um antagonista parcial, agentes que inibe a diferenciação de adipócitos, que acentua ou recupera a função osteogênica, para tratamento ou prevenção de osteoporose, que tem atividade moduladora de ppar gama, diminuidor do açúcar no sangue, para tratamento ou prevenção de diabetes melito, e, para tratamento ou prevenção |
JP2009513523A (ja) * | 2003-07-08 | 2009-04-02 | ノバルティス アクチエンゲゼルシャフト | ベンゼンスルホニルアミノ化合物およびそれらを含む医薬組成物 |
CN101238109B (zh) | 2005-06-09 | 2011-12-14 | 沃泰克斯药物股份有限公司 | 作为离子通道调节剂的茚满衍生物 |
-
2006
- 2006-09-26 JP JP2008533906A patent/JP2009510146A/ja not_active Abandoned
- 2006-09-26 BR BRPI0616872-8A patent/BRPI0616872A2/pt not_active IP Right Cessation
- 2006-09-26 EP EP06792248A patent/EP1937675B1/fr active Active
- 2006-09-26 NZ NZ567204A patent/NZ567204A/en not_active IP Right Cessation
- 2006-09-26 RU RU2008113209/04A patent/RU2008113209A/ru not_active Application Discontinuation
- 2006-09-26 AT AT06792248T patent/ATE513829T1/de not_active IP Right Cessation
- 2006-09-26 KR KR1020087008253A patent/KR20080050607A/ko not_active Application Discontinuation
- 2006-09-26 WO PCT/EP2006/009300 patent/WO2007039174A2/fr active Application Filing
- 2006-09-26 CA CA002624329A patent/CA2624329A1/fr not_active Abandoned
- 2006-09-26 AU AU2006299088A patent/AU2006299088A1/en not_active Abandoned
- 2006-09-26 CN CNA2006800370553A patent/CN101282969A/zh active Pending
- 2006-09-27 TW TW095135655A patent/TW200811120A/zh unknown
- 2006-10-04 AR ARP060104362A patent/AR056563A1/es not_active Application Discontinuation
- 2006-10-06 UY UY29848A patent/UY29848A1/es not_active Application Discontinuation
-
2008
- 2008-03-03 ZA ZA200801989A patent/ZA200801989B/xx unknown
- 2008-03-26 IL IL190459A patent/IL190459A0/en unknown
- 2008-03-31 MA MA30789A patent/MA29811B1/fr unknown
- 2008-04-04 NO NO20081676A patent/NO20081676L/no not_active Application Discontinuation
- 2008-04-04 US US12/062,759 patent/US7612104B2/en not_active Expired - Fee Related
-
2009
- 2009-09-24 US US12/566,179 patent/US7772257B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20100022603A1 (en) | 2010-01-28 |
EP1937675B1 (fr) | 2011-06-22 |
CN101282969A (zh) | 2008-10-08 |
UY29848A1 (es) | 2007-05-31 |
EP1937675A2 (fr) | 2008-07-02 |
US7772257B2 (en) | 2010-08-10 |
WO2007039174A3 (fr) | 2007-08-09 |
JP2009510146A (ja) | 2009-03-12 |
WO2007039174A2 (fr) | 2007-04-12 |
IL190459A0 (en) | 2008-11-03 |
NZ567204A (en) | 2010-06-25 |
BRPI0616872A2 (pt) | 2011-07-05 |
RU2008113209A (ru) | 2009-10-10 |
US7612104B2 (en) | 2009-11-03 |
KR20080050607A (ko) | 2008-06-09 |
ATE513829T1 (de) | 2011-07-15 |
NO20081676L (no) | 2008-04-29 |
ZA200801989B (en) | 2009-08-26 |
US20080293780A1 (en) | 2008-11-27 |
AU2006299088A1 (en) | 2007-04-12 |
CA2624329A1 (fr) | 2007-04-12 |
AR056563A1 (es) | 2007-10-10 |
TW200811120A (en) | 2008-03-01 |
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