MA29044B1 - Formulations inmunotherapeutiques a capacite de neutralisation de l'interleukine-2 - Google Patents

Formulations inmunotherapeutiques a capacite de neutralisation de l'interleukine-2

Info

Publication number
MA29044B1
MA29044B1 MA29960A MA29960A MA29044B1 MA 29044 B1 MA29044 B1 MA 29044B1 MA 29960 A MA29960 A MA 29960A MA 29960 A MA29960 A MA 29960A MA 29044 B1 MA29044 B1 MA 29044B1
Authority
MA
Morocco
Prior art keywords
inmunotherapeutic
interleukin
formulations
neutralization capacity
neutralization
Prior art date
Application number
MA29960A
Other languages
English (en)
Inventor
Casimiro Jose Enrique Montero
Sarduy Livan Bladimir Alonso
Rodriguez Rolando Perez
Davila Agustin Bienvenido Lage
Original Assignee
Ct De Inmunolgia Molecular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct De Inmunolgia Molecular filed Critical Ct De Inmunolgia Molecular
Publication of MA29044B1 publication Critical patent/MA29044B1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/55IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA29960A 2004-11-16 2007-05-30 Formulations inmunotherapeutiques a capacite de neutralisation de l'interleukine-2 MA29044B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20040261A CU23297A1 (es) 2004-11-16 2004-11-16 Formulaciones inmunoterapã0/00uticas para la inducciã"n de autoanticuerpos bloqueadores de la uniã"n de interleucina-2 a su receptor. su uso en el tratamiento del cã ncer

Publications (1)

Publication Number Publication Date
MA29044B1 true MA29044B1 (fr) 2007-11-01

Family

ID=40122436

Family Applications (1)

Application Number Title Priority Date Filing Date
MA29960A MA29044B1 (fr) 2004-11-16 2007-05-30 Formulations inmunotherapeutiques a capacite de neutralisation de l'interleukine-2

Country Status (25)

Country Link
US (1) US20090274647A1 (fr)
EP (2) EP1829893B1 (fr)
JP (1) JP5227028B2 (fr)
KR (1) KR101240457B1 (fr)
CN (1) CN101061136B (fr)
AR (1) AR051494A1 (fr)
AT (1) ATE525393T1 (fr)
AU (1) AU2005306186B2 (fr)
BR (1) BRPI0518007A (fr)
CA (1) CA2588573C (fr)
CR (1) CR9097A (fr)
CU (1) CU23297A1 (fr)
EA (1) EA012072B1 (fr)
GE (1) GEP20105039B (fr)
HK (1) HK1113374A1 (fr)
MA (1) MA29044B1 (fr)
MX (1) MX2007005808A (fr)
MY (1) MY162106A (fr)
PE (1) PE20061172A1 (fr)
SG (1) SG122897A1 (fr)
TN (1) TNSN07187A1 (fr)
TR (1) TR200704213T2 (fr)
TW (1) TWI433853B (fr)
WO (1) WO2006053508A1 (fr)
ZA (1) ZA200703528B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009542592A (ja) * 2006-07-06 2009-12-03 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング Il−2媒介性免疫応答の有効性を高める組成物および方法
WO2015162124A1 (fr) * 2014-04-22 2015-10-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Méthodes de diagnostic d'une maladie auto-immune
US10138298B2 (en) 2015-10-23 2018-11-27 The Regents Of The University Of California Anti-IL-2 antibodies and compositions and uses thereof
MX2019014023A (es) 2017-05-24 2020-02-17 Novartis Ag Proteinas de anticuerpo injertadas con citocina y metodos de uso en el tratamiento del cancer.
CU20210021A7 (es) * 2021-03-30 2022-11-07 Ct Inmunologia Molecular Composicones vacunales depletantes de factores de crecimiento hematopoyéticos para el tratamiento de enfermedades inflamatorias

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5939832A (ja) * 1982-08-28 1984-03-05 Ajinomoto Co Inc モノクロ−ナル抗体ならびにその製法、使用法
JPS59116231A (ja) * 1982-12-13 1984-07-05 スロ−ン−ケツタリング・インステイテユ−ト・フオ−・キヤンサ−・リサ−チ 抗−インタ−ロイキン−2単クロ−ン抗体
US4569790A (en) * 1984-03-28 1986-02-11 Cetus Corporation Process for recovering microbially produced interleukin-2 and purified recombinant interleukin-2 compositions
US5643565A (en) * 1985-09-20 1997-07-01 Chiron Corporation Human IL-2 as a vaccine adjuvant
JPH04506662A (ja) * 1989-07-14 1992-11-19 アメリカン・サイアナミド・カンパニー 接合体ワクチンのためのサイトカイニンおよびホルモンのキヤリヤー
HUT60768A (en) * 1990-03-16 1992-10-28 Sandoz Ag Process for producing cd25 fixing molecules
CU22302A1 (es) 1990-09-07 1995-01-31 Cigb Secuencia nucleotidica codificante para una proteina de la membrana externa de neisseria meningitidis y uso de dicha proteina en preparados vacunales
US5830452A (en) 1990-11-20 1998-11-03 Chiron Corporation Method for enhancing the anti-tumor therapeutic index of interleukin-2
JPH10147952A (ja) 1996-11-18 1998-06-02 Komatsu Ltd ブルドーザのドージング装置
US20040156824A1 (en) * 1996-12-23 2004-08-12 Epstein Alan L. Vasopermeability enhancing peptide of human interleukin-2 and immunoconjugates thereof
CA2219961C (fr) * 1998-01-09 2010-06-01 The University Of Southern California Vasopermeabilite ameliorant les peptides de l'interleukine-2 chez l'humain et les immunoconjugues
CU22731A1 (es) * 1998-02-05 2002-02-28 Centro Inmunologia Molecular Anticuerpo monoclonal que reconoce el oligosacárido ácido siálico n´glicolilado-galactosa-glucosa (ngcneu-gal-glu) en tumores malignos y composiciones farmacéuticas que los contienen
US6168785B1 (en) * 1998-07-16 2001-01-02 Institut Pasteur Biological applications of new peptides of IL-2 and derivatives and use as therapeutic agents
CN1192796C (zh) * 1999-02-12 2005-03-16 斯克里普斯研究学院 联合应用抗血管生成和免疫治疗以治疗肿瘤和转移的方法
WO2001080889A1 (fr) * 2000-04-26 2001-11-01 National Jewish Medical And Research Center Regulation de la reponse des lymphocytes t et produit a cet effet
CU23011A1 (es) * 2000-11-03 2004-12-17 Ct Ingenieria Genetica Biotech Método de obtención de estructuras antigénicas quemétodo de obtención de estructuras antigénicas que potencian la reactividad cruzada específica y su potencian la reactividad cruzada específica y su uso en formulaciones uso en formulaciones
CU23077A1 (es) * 2000-12-06 2005-08-17 Centro Inmunologia Molecular Composicion vacunal que contiene factor de crecimiento transformante (tgf-alfa). su uso en la terapia de enfermedades malignas
CU22979A1 (es) * 2000-12-08 2004-09-09 Centro Inmunologia Molecular Combinación inmunoterapéutica para el tratamiento de tumores que sobre-expresan receptores con actividad quinasa en residuos de tirosina
CU22999A1 (es) * 2001-12-04 2004-10-12 Centro Inmunologia Molecular Método de tratamiento de enfermedades malignas e infecciosas crónicas
WO2002087304A2 (fr) * 2001-04-30 2002-11-07 Frohnhofen, Wilfried Peptides d'interleukine-2 et peptides et dimeres peptidiques derives d'interleukine-2
US6906169B2 (en) * 2001-05-25 2005-06-14 United Biomedical, Inc. Immunogenic peptide composition comprising measles virus Fprotein Thelper cell epitope (MUFThl-16) and N-terminus of β-amyloid peptide
ITMI20012527A1 (it) 2001-11-30 2003-05-30 Unihart Corp Proteine di fusione contenenti peptidi tlp
DK1461073T3 (da) * 2001-11-30 2010-03-29 Us Gov Health & Human Serv Peptidagonister til prostataspecifikt antigen og anvendelser heraf
US20040208869A1 (en) * 2003-01-30 2004-10-21 Medimmune, Inc. Uses of anti-integrin alphanubeta3 antibody formulations
WO2005007121A2 (fr) * 2003-07-18 2005-01-27 Massachusetts Institute Of Technology Polypeptides de l'interleukine-2(il-2) mutante

Also Published As

Publication number Publication date
EA012072B1 (ru) 2009-08-28
GEP20105039B (en) 2010-07-12
TNSN07187A1 (en) 2008-11-21
AU2005306186B2 (en) 2012-05-31
MY162106A (en) 2017-05-31
CN101061136A (zh) 2007-10-24
AR051494A1 (es) 2007-01-17
CU23297A1 (es) 2008-07-24
CN101061136B (zh) 2012-12-05
EP1829893B1 (fr) 2011-09-21
CR9097A (es) 2007-08-28
TWI433853B (zh) 2014-04-11
JP5227028B2 (ja) 2013-07-03
KR20070084025A (ko) 2007-08-24
SG122897A1 (en) 2006-06-29
CA2588573A1 (fr) 2006-05-26
JP2008526686A (ja) 2008-07-24
EP2112160A3 (fr) 2010-01-13
EA200701071A1 (ru) 2007-12-28
KR101240457B1 (ko) 2013-03-08
AU2005306186A1 (en) 2006-05-26
EP2112160B1 (fr) 2015-07-08
ATE525393T1 (de) 2011-10-15
EP2112160A2 (fr) 2009-10-28
BRPI0518007A (pt) 2008-10-21
TR200704213T2 (tr) 2007-08-21
EP1829893A1 (fr) 2007-09-05
TW200631591A (en) 2006-09-16
CA2588573C (fr) 2013-12-31
HK1113374A1 (en) 2008-10-03
MX2007005808A (es) 2007-07-20
WO2006053508A1 (fr) 2006-05-26
ZA200703528B (en) 2008-06-25
PE20061172A1 (es) 2006-12-16
US20090274647A1 (en) 2009-11-05

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