MA26606A1 - Derives de 5-desoxycytidine, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation. - Google Patents

Derives de 5-desoxycytidine, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation.

Info

Publication number
MA26606A1
MA26606A1 MA25456A MA25456A MA26606A1 MA 26606 A1 MA26606 A1 MA 26606A1 MA 25456 A MA25456 A MA 25456A MA 25456 A MA25456 A MA 25456A MA 26606 A1 MA26606 A1 MA 26606A1
Authority
MA
Morocco
Prior art keywords
desoxycytidine
derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
MA25456A
Other languages
English (en)
Inventor
Hattori Kazuo
Ishikawa Tohru
Ishitsuka Hideo
Kohchi Yasunori
Oikawa Nobuhiro
Shimma Nobuo
Suda Hitomi
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA26606A1 publication Critical patent/MA26606A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA25456A 1998-02-06 1999-02-05 Derives de 5-desoxycytidine, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation. MA26606A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98102080 1998-02-06
EP98108321 1998-05-07

Publications (1)

Publication Number Publication Date
MA26606A1 true MA26606A1 (fr) 2004-12-20

Family

ID=26149007

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25456A MA26606A1 (fr) 1998-02-06 1999-02-05 Derives de 5-desoxycytidine, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation.

Country Status (19)

Country Link
US (1) US6005098A (fr)
EP (1) EP1060183B1 (fr)
JP (2) JP3625276B2 (fr)
KR (1) KR100381516B1 (fr)
CN (1) CN1260240C (fr)
AR (1) AR014539A1 (fr)
AT (1) ATE238335T1 (fr)
AU (1) AU757136B2 (fr)
BR (1) BR9907672A (fr)
CA (1) CA2318848C (fr)
CO (1) CO5070642A1 (fr)
DE (1) DE69907161T2 (fr)
DK (1) DK1060183T3 (fr)
ES (1) ES2195543T3 (fr)
MA (1) MA26606A1 (fr)
PE (1) PE20000244A1 (fr)
PT (1) PT1060183E (fr)
TR (1) TR200002297T2 (fr)
WO (1) WO1999040099A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030119724A1 (en) * 1995-11-22 2003-06-26 Ts`O Paul O.P. Ligands to enhance cellular uptake of biomolecules
EP0882734B1 (fr) * 1997-06-02 2009-08-26 F. Hoffmann-La Roche Ag Dérivés de 5'-déoxy-cytidine
DK1057831T3 (da) 1999-05-26 2005-01-31 Hoffmann La Roche Fremgangsmåde til fremstilling af vinylpyrimidinderivater
KR100631754B1 (ko) * 2000-08-09 2006-10-09 주식회사 코오롱 Ｎ-알킬옥시카르보닐-5-플루오로사이토신 유도체 및 그의제조방법
CN100406065C (zh) 2000-12-01 2008-07-30 细胞工厂治疗公司 糖基化/半乳糖基化肽、双官能接头和核苷酸单体/多聚体的缀合物以及相关的组合物和使用方法
CN100383128C (zh) * 2004-02-23 2008-04-23 上海迪赛诺医药发展有限公司 N4－氧羰基胞嘧啶衍生物及制备方法与应用
ES2327195B1 (es) * 2005-04-12 2010-07-09 Elan Pharma International Limited Composiciones de liberacion modificada que comprenden un derivado de fluorocitidina para el tratamiento del cancer.
JP6866113B2 (ja) * 2016-11-01 2021-04-28 日本化薬株式会社 カペシタビンを有効成分とする医薬製剤
JP6792418B2 (ja) * 2016-11-08 2020-11-25 日本化薬株式会社 カペシタビンを有効成分とする医薬製剤の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561290A (en) * 1975-10-16 1980-02-20 Nyegaard & Co As Pyrimid - 2 - ones
JPS54129131A (en) * 1978-03-27 1979-10-06 Taiho Pharmaceutical Co Ltd Antiimalignant tumor agent composition
GB2016921B (en) * 1978-03-27 1982-08-18 Taiho Pharmaceutical Co Ltd Anti cancer compositions containing uracil derivatives
US4328229A (en) * 1978-03-29 1982-05-04 Taiho Pharmaceutical Company Limited Anti-cancer composition for delivering 5-fluorouracil to cancer tissues
CA1327358C (fr) * 1987-11-17 1994-03-01 Morio Fujiu Derives fluorocytidine
ATE161722T1 (de) * 1990-07-19 1998-01-15 Wellcome Found Enzyminaktivatoren
GB9020930D0 (en) * 1990-09-26 1990-11-07 Wellcome Found Pharmaceutical combinations
DE122011100040I2 (de) * 1991-05-27 2012-08-09 Taiho Pharmaceutical Co Ltd Zusammensetzung, verfahren und instrument zur potenzierung der antitumoraktivitat und zur behandlungvon tumoren.
TW254946B (fr) * 1992-12-18 1995-08-21 Hoffmann La Roche
AU671491B2 (en) * 1992-12-18 1996-08-29 F. Hoffmann-La Roche Ag N-oxycarbonyl substituted 5'-deoxy-5-fluorcytidines
EP0882734B1 (fr) * 1997-06-02 2009-08-26 F. Hoffmann-La Roche Ag Dérivés de 5'-déoxy-cytidine

Also Published As

Publication number Publication date
KR20010072543A (ko) 2001-07-31
EP1060183A1 (fr) 2000-12-20
CO5070642A1 (es) 2001-08-28
AR014539A1 (es) 2001-02-28
PT1060183E (pt) 2003-08-29
PE20000244A1 (es) 2000-04-10
WO1999040099A1 (fr) 1999-08-12
BR9907672A (pt) 2000-11-28
ES2195543T3 (es) 2003-12-01
CA2318848C (fr) 2008-09-02
CN1290269A (zh) 2001-04-04
JP2004339230A (ja) 2004-12-02
DE69907161D1 (de) 2003-05-28
US6005098A (en) 1999-12-21
CA2318848A1 (fr) 1999-08-12
KR100381516B1 (ko) 2003-04-23
EP1060183B1 (fr) 2003-04-23
DK1060183T3 (da) 2003-08-11
CN1260240C (zh) 2006-06-21
JP2002502857A (ja) 2002-01-29
DE69907161T2 (de) 2004-02-05
JP3625276B2 (ja) 2005-03-02
ATE238335T1 (de) 2003-05-15
TR200002297T2 (tr) 2000-12-21
AU2722799A (en) 1999-08-23
AU757136B2 (en) 2003-02-06

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