MA24569A1 - Inhibiteurs de farnesyl-transferase en association avec des inhibiteurs de hmg-coa-reductase pour le traitement du cancer - Google Patents

Inhibiteurs de farnesyl-transferase en association avec des inhibiteurs de hmg-coa-reductase pour le traitement du cancer

Info

Publication number
MA24569A1
MA24569A1 MA25114A MA25114A MA24569A1 MA 24569 A1 MA24569 A1 MA 24569A1 MA 25114 A MA25114 A MA 25114A MA 25114 A MA25114 A MA 25114A MA 24569 A1 MA24569 A1 MA 24569A1
Authority
MA
Morocco
Prior art keywords
inhibitors
farnesyl
hmg
coa
cancer
Prior art date
Application number
MA25114A
Other languages
English (en)
Inventor
Mohamed Kajiji Shama
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MA24569A1 publication Critical patent/MA24569A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MA25114A 1997-06-16 1998-06-15 Inhibiteurs de farnesyl-transferase en association avec des inhibiteurs de hmg-coa-reductase pour le traitement du cancer MA24569A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4963897P 1997-06-16 1997-06-16

Publications (1)

Publication Number Publication Date
MA24569A1 true MA24569A1 (fr) 1998-12-31

Family

ID=21960890

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25114A MA24569A1 (fr) 1997-06-16 1998-06-15 Inhibiteurs de farnesyl-transferase en association avec des inhibiteurs de hmg-coa-reductase pour le traitement du cancer

Country Status (37)

Country Link
EP (1) EP0986387B1 (fr)
JP (1) JP3713051B2 (fr)
KR (1) KR100392573B1 (fr)
CN (1) CN1259868A (fr)
AP (1) AP9801261A0 (fr)
AR (1) AR013090A1 (fr)
AT (1) ATE235905T1 (fr)
BG (1) BG103946A (fr)
BR (1) BR9810616A (fr)
CA (1) CA2294399C (fr)
CO (1) CO4950607A1 (fr)
DE (1) DE69812933T2 (fr)
DK (1) DK0986387T3 (fr)
DZ (1) DZ2518A1 (fr)
EA (1) EA199901043A1 (fr)
ES (1) ES2196559T3 (fr)
GT (1) GT199800081A (fr)
HN (1) HN1998000091A (fr)
HR (1) HRP980328B1 (fr)
HU (1) HUP0004624A3 (fr)
ID (1) ID23014A (fr)
IL (1) IL132765A0 (fr)
IS (1) IS5259A (fr)
MA (1) MA24569A1 (fr)
NO (1) NO996206L (fr)
NZ (1) NZ500662A (fr)
OA (1) OA11231A (fr)
PA (1) PA8453601A1 (fr)
PE (1) PE82899A1 (fr)
PL (1) PL337651A1 (fr)
PT (1) PT986387E (fr)
SK (1) SK169699A3 (fr)
TN (1) TNSN98088A1 (fr)
TR (1) TR199903074T2 (fr)
UA (1) UA57081C2 (fr)
WO (1) WO1998057633A1 (fr)
ZA (1) ZA985182B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1077949A2 (fr) * 1998-05-12 2001-02-28 Warner-Lambert Company Combinaisons d'inhibiteurs de proteine farnesyltransferase et de hmg coa reductase et leurs utilisations dans le traitement du cancer
WO2000016778A1 (fr) * 1998-09-24 2000-03-30 Merck & Co., Inc. Procede de traitement du cancer
EP1006113A1 (fr) * 1998-12-02 2000-06-07 Pfizer Products Inc. Dérivés de 2-(2-oxo-éthylidène)-imidazolidin-4-one et leur utilisation pour inhiber la croissance anormale des cellules
WO2000067737A2 (fr) * 1999-05-07 2000-11-16 The Brigham And Women's Hospital, Inc. UTILISATION D'INHIBITEURS DE HMGCoA REDUCTASE POUR LA PREVENTION DE MALADIES DONT LA PATHOGENESE DEPEND D'UNE NEOFORMATION DE VAISSEAUX SANGUINS
US6710058B2 (en) 2000-11-06 2004-03-23 Bristol-Myers Squibb Pharma Company Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors
MXPA03005525A (es) 2000-12-19 2003-10-06 Pfizer Prod Inc Formas cristalinas de sales de 2,3-dihidroxibutanodioato de 6-[(4-cloro -fenil)- hidroxi-(3 -metil-3h-imidazol -4-il)-metil] -4-(3-etinil-fenil) -1-metil-1h -quinolein-2 -ona, y metodo de produccion.
US6706724B2 (en) 2000-12-21 2004-03-16 Nitromed, Inc. Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
US20020151563A1 (en) * 2001-03-29 2002-10-17 Pfizer Inc. Farnesyl transferase inhibitors in combination with HMG CoA reductase inhibitors for the inhibition of abnormal cell growth
US6740757B2 (en) 2001-08-29 2004-05-25 Pfizer Inc Enantiomers of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3h-imidazol-4-yl)-methyl]-4-[3-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1h-quinolin-2-one and salts thereof, useful in the treatment of cancer
EP1555021A1 (fr) * 2004-01-16 2005-07-20 National Health Research Institutes Combinaisons d'un inhibiteur de la voie du mévalonate et d'un agoniste PPAR-gamma pour le traitement du cancer
US8168667B2 (en) 2006-05-31 2012-05-01 Galapagos Nv Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such
GB2463514C (en) 2008-09-11 2018-09-26 Galapagos Nv Imidazolidine compounds and uses therefor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE302613T1 (de) * 1995-08-09 2005-09-15 Banyu Pharma Co Ltd Proteinfarnesyltransferase-inhibitoren in kombination mit hmgcoa-reduktase-inhibitoren zur behandlung von aids

Also Published As

Publication number Publication date
TR199903074T2 (xx) 2000-05-22
BR9810616A (pt) 2000-09-12
KR100392573B1 (ko) 2003-07-23
DE69812933T2 (de) 2003-11-06
AR013090A1 (es) 2000-12-13
PL337651A1 (en) 2000-08-28
IS5259A (is) 1999-11-19
HUP0004624A2 (hu) 2001-10-28
IL132765A0 (en) 2001-03-19
JP2000513031A (ja) 2000-10-03
GT199800081A (es) 1999-12-07
AP9801261A0 (en) 1999-12-11
PT986387E (pt) 2003-06-30
HRP980328B1 (en) 2002-06-30
NZ500662A (en) 2001-10-26
CA2294399C (fr) 2004-03-16
UA57081C2 (uk) 2003-06-16
EA199901043A1 (ru) 2000-06-26
ATE235905T1 (de) 2003-04-15
BG103946A (bg) 2000-07-31
EP0986387A1 (fr) 2000-03-22
SK169699A3 (en) 2000-06-12
DE69812933D1 (de) 2003-05-08
ID23014A (id) 1999-12-30
EP0986387B1 (fr) 2003-04-02
CA2294399A1 (fr) 1998-12-23
NO996206L (no) 2000-02-15
NO996206D0 (no) 1999-12-15
WO1998057633A1 (fr) 1998-12-23
CN1259868A (zh) 2000-07-12
OA11231A (en) 2003-05-26
TNSN98088A1 (fr) 2005-03-15
PA8453601A1 (es) 2000-05-24
HUP0004624A3 (en) 2002-11-28
HN1998000091A (es) 1999-09-29
AU7445998A (en) 1999-01-04
KR20010013839A (ko) 2001-02-26
CO4950607A1 (es) 2000-09-01
DZ2518A1 (fr) 2003-02-01
ZA985182B (en) 1999-12-17
ES2196559T3 (es) 2003-12-16
PE82899A1 (es) 1999-08-26
DK0986387T3 (da) 2003-07-14
HRP980328A2 (en) 1999-04-30
AU724676B2 (en) 2000-09-28
JP3713051B2 (ja) 2005-11-02

Similar Documents

Publication Publication Date Title
FR12C0077I2 (fr) Composition pour le traitement des condylomes génitaux
CY2006007I1 (el) Χρηση αναστολεων cgmp-φωσφοδιεστερασης στην αγωγη της ανικανοτητας
NO986052L (no) Anticonvulsivt virkende sulfamatderivater for anvendelse ved behandling av fedme
DE69624812D1 (de) Verringerung des mehrwegeffekts in gps-empfängern
IL142908A0 (en) Compounds useful in the treatment of inflammatory diseases
DE69838374D1 (de) Prozessor und Verfahren zum Verringern von dessen Energieverbrauch
FR08C0013I2 (fr) Utilisation de et743 en thérapie combinée avec dexaméthasone pour traiter le cancer
FR2775078B1 (fr) Procede et dispositif pour le traitement de vaisselle dans des lave-vaisselle
MA24569A1 (fr) Inhibiteurs de farnesyl-transferase en association avec des inhibiteurs de hmg-coa-reductase pour le traitement du cancer
MA25234A1 (fr) Vibromasseur pour le soulagement des maux et de la douleur.
ZA964762B (en) Peptidyl heterocycles useful in the treatment of thrombin related disorders.
ZA964761B (en) Peptidyl heterocycles useful in the treatment of thrombin related disorders.
NZ307958A (en) Benzisoxazole and indazole derivatives as long acting antipsychotic agents and particularly in the treatment of schizophrenia
DZ2665A1 (fr) Conjugués utiles pour le traitement du cancer de la prostate.
HK1025954A1 (en) Triptolide derivatives useful in the treatment of autoimmune diseases
NO20004459L (no) Sensor for anvendelse i flytende metaller
ZA958558B (en) Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases
IL141056A0 (en) Protease inhibitors for use in the treatment of psoriasis
DE69713442D1 (de) Thioürazil-Derivate und diese enthaltende Metall-Oberflächebehandlungsmittel
IT1268346B1 (it) Metodo per la fabbricazione di ferri da stiro con soletta in acciaio
FR2751572B1 (fr) Procede pour traiter superficiellement des pieces embouties et pieces obtenues suivant ce procede
GB9608966D0 (en) Improvements in and relating to an apparatus for the treatment of water
FR2747298B1 (fr) Le decortiqueur pour la consommation de crustaces
KR980003137U (ko) 퇴수를 재공급 사용토록 한 개량부동전
GB9825969D0 (en) Agents useful in the treatment of reproductive disorders