MA23832A1 - Derives d'acide hydroxamique nouveaux, procede pour leur production et compositions les contenant - Google Patents

Derives d'acide hydroxamique nouveaux, procede pour leur production et compositions les contenant

Info

Publication number
MA23832A1
MA23832A1 MA24191A MA24191A MA23832A1 MA 23832 A1 MA23832 A1 MA 23832A1 MA 24191 A MA24191 A MA 24191A MA 24191 A MA24191 A MA 24191A MA 23832 A1 MA23832 A1 MA 23832A1
Authority
MA
Morocco
Prior art keywords
production
compositions containing
acid derivatives
hydroxamic acid
novel hydroxamic
Prior art date
Application number
MA24191A
Other languages
English (en)
Inventor
Ito Fumitaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MA23832A1 publication Critical patent/MA23832A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
MA24191A 1995-03-31 1996-03-25 Derives d'acide hydroxamique nouveaux, procede pour leur production et compositions les contenant MA23832A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9500631 1995-03-31

Publications (1)

Publication Number Publication Date
MA23832A1 true MA23832A1 (fr) 1996-10-01

Family

ID=14125824

Family Applications (1)

Application Number Title Priority Date Filing Date
MA24191A MA23832A1 (fr) 1995-03-31 1996-03-25 Derives d'acide hydroxamique nouveaux, procede pour leur production et compositions les contenant

Country Status (35)

Country Link
US (2) US5952369A (fr)
EP (1) EP0817772B1 (fr)
JP (1) JP3035356B2 (fr)
KR (1) KR100258657B1 (fr)
AP (1) AP625A (fr)
AR (1) AR002729A1 (fr)
AT (1) ATE231840T1 (fr)
AU (1) AU693336B2 (fr)
BG (1) BG62611B1 (fr)
BR (1) BR9607750A (fr)
CA (1) CA2213815C (fr)
CZ (1) CZ306497A3 (fr)
DE (1) DE69626009T2 (fr)
DK (1) DK0817772T3 (fr)
ES (1) ES2188743T3 (fr)
HR (1) HRP960141A2 (fr)
HU (1) HUP9900767A3 (fr)
IL (2) IL117440A0 (fr)
IS (1) IS4547A (fr)
LV (1) LV11971B (fr)
MA (1) MA23832A1 (fr)
NO (1) NO974513D0 (fr)
NZ (1) NZ304113A (fr)
OA (1) OA10518A (fr)
PE (1) PE43397A1 (fr)
PL (1) PL322652A1 (fr)
RU (1) RU2144917C1 (fr)
SI (1) SI9620039A (fr)
SK (1) SK129897A3 (fr)
TN (1) TNSN96045A1 (fr)
TR (1) TR199701082T1 (fr)
TW (1) TW408111B (fr)
WO (1) WO1996030339A1 (fr)
YU (1) YU18696A (fr)
ZA (1) ZA962476B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9701042A (es) * 1996-02-07 1998-05-31 Pfizer Compuestos del acido hidroxamico.
TNSN97092A1 (ar) 1996-09-18 1999-12-31 Agouron Pharma مثبطات انزيم بروتيني فلزي وتركيبات صيدلانية تحتوي على تلك المثبتطات واستخدامها الصيدلاني وطرق ومركبات وسيطة مفيدة لتحضير التركيبات المذكورة.
ATE235903T1 (de) * 1996-12-02 2003-04-15 Kyorin Seiyaku Kk Neue derivate von n-substituierten pyrrolidin derivaten und deren herstellungsverfahren
CA2276074A1 (fr) * 1997-01-10 1998-07-16 Merck & Co., Inc. Synthese efficace d'un mediateur chiral
EP0982297A3 (fr) * 1998-08-24 2001-08-01 Pfizer Products Inc. Procédé de préparation de dérivés de acide hydroxamique substitués par hydroxy-pyrrolidinyl, qui sont agonistes du récepteur opioid kappa
KR100295740B1 (ko) * 1998-09-17 2001-11-05 박영구 N-치환된-하이드록시고리화알킬아민유도체의제조방법
US6444829B1 (en) * 2000-07-19 2002-09-03 Hoffmann-La Roche Inc. Pyrrolidine compounds
WO2002088082A2 (fr) 2001-04-30 2002-11-07 Pfizer Products Inc. Procede de preparation de composes d'ethylamine d'hydroxypyrrolidinyle utilises comme agonistes de kappa
US7091357B2 (en) * 2001-12-26 2006-08-15 University Of Kentucky Research Foundation Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies
WO2004039785A1 (fr) * 2002-11-01 2004-05-13 Pfizer Products Inc. Procede servant a preparer des composes de pyrolidinyle ethylamine par l'intermediaire d'une arylamination provoquee par du cuivre
GB0821010D0 (en) * 2008-11-17 2008-12-24 Univ Warwick Plant development control composition
AU2012255690B2 (en) 2011-05-16 2015-06-11 Bionomics Limited Amine derivatives as potassium channel blockers
AU2013230425B2 (en) * 2012-03-05 2017-05-25 Dr.Reddy's Laboratories Ltd. Substituted heterocyclic acetamides as kappa opioid receptor (kor) agonists
GB201210395D0 (en) * 2012-06-11 2012-07-25 Syngenta Participations Ag Crop enhancement compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3268539A (en) * 1963-05-20 1966-08-23 Universal Oil Prod Co Tertiary-aminoalkyl derivatives of diaryl substituted acetohydroxamic acid esters

Also Published As

Publication number Publication date
PL322652A1 (en) 1998-02-16
CA2213815A1 (fr) 1996-10-03
DK0817772T3 (da) 2003-05-19
SI9620039A (sl) 1998-08-31
CA2213815C (fr) 2001-12-18
IL117440A0 (en) 1996-07-23
TW408111B (en) 2000-10-11
AP9600791A0 (en) 1996-04-30
SK129897A3 (en) 1998-11-04
ATE231840T1 (de) 2003-02-15
CZ306497A3 (cs) 1998-07-15
RU2144917C1 (ru) 2000-01-27
EP0817772B1 (fr) 2003-01-29
TNSN96045A1 (fr) 2005-03-15
US6110947A (en) 2000-08-29
JPH11501048A (ja) 1999-01-26
KR19980703476A (ko) 1998-11-05
HUP9900767A2 (hu) 1999-07-28
DE69626009D1 (de) 2003-03-06
MX9707454A (es) 1998-07-31
BG101896A (en) 1999-01-29
US5952369A (en) 1999-09-14
LV11971B (en) 1998-06-20
NO974513L (no) 1997-09-29
PE43397A1 (es) 1997-10-13
LV11971A (lv) 1998-02-20
AU5121196A (en) 1996-10-16
NZ304113A (en) 1999-01-28
ZA962476B (en) 1997-09-29
EP0817772A1 (fr) 1998-01-14
AR002729A1 (es) 1998-04-29
DE69626009T2 (de) 2003-08-14
BG62611B1 (bg) 2000-03-31
BR9607750A (pt) 1998-06-30
TR199701082T1 (xx) 1998-02-21
KR100258657B1 (ko) 2000-07-01
AP625A (en) 1997-12-24
HUP9900767A3 (en) 2001-01-29
ES2188743T3 (es) 2003-07-01
WO1996030339A1 (fr) 1996-10-03
AU693336B2 (en) 1998-06-25
OA10518A (en) 2002-04-22
YU18696A (sh) 1999-06-15
JP3035356B2 (ja) 2000-04-24
IS4547A (is) 1997-08-19
IL129479A0 (en) 2000-02-29
NO974513D0 (no) 1997-09-29
HRP960141A2 (en) 1997-10-31

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