LV5768B4 - [[[(3-Piridinil)metilen]amino]oksi]alkanskabes un esteri - Google Patents

[[[(3-Piridinil)metilen]amino]oksi]alkanskabes un esteri

Info

Publication number
LV5768B4
LV5768B4 LV960188A LV960188A LV5768B4 LV 5768 B4 LV5768 B4 LV 5768B4 LV 960188 A LV960188 A LV 960188A LV 960188 A LV960188 A LV 960188A LV 5768 B4 LV5768 B4 LV 5768B4
Authority
LV
Latvia
Prior art keywords
sub
pyridinyl
methylen
oxy
esters
Prior art date
Application number
LV960188A
Other languages
English (en)
Latvian (lv)
Other versions
LV5768A4 (lv
Inventor
Eddy Jean Edgard Freyne
Alfons Herman Marg Raeymaekers
Victor Sipido
Marc Gaston Venet
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LV5768A4 publication Critical patent/LV5768A4/xx
Publication of LV5768B4 publication Critical patent/LV5768B4/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LV960188A 1985-11-04 1996-06-18 [[[(3-Piridinil)metilen]amino]oksi]alkanskabes un esteri LV5768B4 (lv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79499985A 1985-11-04 1985-11-04
US06/888,670 US4746671A (en) 1985-11-04 1986-07-23 Pharmaceutical use of [[[(3-pyridinyl)methylen]amino]oxy]alkanoic acids and esters
EP86201836A EP0221601B1 (en) 1985-11-04 1986-10-22 [[[(3-Pyridinyl)methylen]amino]oxy]alkanoic acids and esters

Publications (2)

Publication Number Publication Date
LV5768A4 LV5768A4 (lv) 1996-12-20
LV5768B4 true LV5768B4 (lv) 1997-06-20

Family

ID=27121572

Family Applications (1)

Application Number Title Priority Date Filing Date
LV960188A LV5768B4 (lv) 1985-11-04 1996-06-18 [[[(3-Piridinil)metilen]amino]oksi]alkanskabes un esteri

Country Status (21)

Country Link
US (1) US4746671A (xx)
EP (1) EP0221601B1 (xx)
JP (1) JPH0670014B2 (xx)
AT (1) ATE86613T1 (xx)
AU (1) AU587873B2 (xx)
CA (2) CA1298580C (xx)
CS (1) CS382391A3 (xx)
CY (1) CY1864A (xx)
DE (1) DE3687945T2 (xx)
DK (2) DK164159C (xx)
ES (1) ES2002015A6 (xx)
FI (1) FI85372C (xx)
GR (1) GR862634B (xx)
HK (1) HK114595A (xx)
IE (1) IE59775B1 (xx)
IL (1) IL80467A (xx)
LV (1) LV5768B4 (xx)
NO (1) NO170974C (xx)
NZ (1) NZ218121A (xx)
PT (1) PT83667B (xx)
SG (1) SG119194G (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8820578D0 (en) * 1988-08-31 1988-09-28 Glaxo Group Ltd Chemical compositions
JP2765876B2 (ja) * 1988-10-24 1998-06-18 科研製薬株式会社 ピリジルケトオキシムエーテル誘導体
FR2722193B1 (fr) * 1994-07-08 1996-10-04 Sanofi Sa Derives n-oxydes de 1-(7-chloro-4-quinoleinyl)pyrazole-3-carboxamides substitues, procede pour leur preparation et les compositions pharmaceitiques les contenant
EP0817631A2 (en) * 1995-03-28 1998-01-14 Janssen Pharmaceutica N.V. Low dose ridogrel formulations and their use for the treatment of inflammatory bowel diseases
GB9620709D0 (en) * 1996-10-04 1996-11-20 Danbiosyst Uk Colonic delivery of weak acid drugs
WO2009105140A2 (en) 2007-12-11 2009-08-27 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
EA027433B1 (ru) * 2012-10-08 2017-07-31 Дафот Энтерпраизес Лимитед Производное оксима бензоилпиридина, обладающее противосудорожной активностью

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003734A (en) * 1974-01-22 1977-01-18 The Dow Chemical Company Substituted pyridinyloxy(thio)phenyl-acetamides, -ureas and urea derivatives and herbicidal compositions and methods containing said compounds
DE2415063A1 (de) * 1974-03-28 1975-10-16 Bayer Ag Pyridylalkylamidine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
CH616406A5 (en) * 1975-06-27 1980-03-31 Siegfried Ag Process for the preparation of novel oxime derivatives
US4092419A (en) * 1976-06-15 1978-05-30 Merck & Co., Inc. Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, their preparation and use
US4297359A (en) * 1978-07-25 1981-10-27 Acf Chemiefarma Nv Anti-ulcer compositions containing certain pyridyl oxime ethers
NL8000869A (nl) * 1979-02-16 1980-08-19 Eisai Co Ltd Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan.
US4518602A (en) * 1982-10-07 1985-05-21 Takeda Chemical Industries, Ltd. Vinyl carboxylic acid derivatives, their production and use as inhibitors of thromboxane synthetase
GB8311003D0 (en) * 1983-04-22 1983-05-25 Shell Int Research Aniline compounds
JPS6078966A (ja) * 1983-10-04 1985-05-04 Nippon Tokushu Noyaku Seizo Kk トリクロルアクリロイルオキシム誘導体,その製法及び農業用殺菌剤
IT1175720B (it) * 1984-09-13 1987-07-15 Baldacci Lab Spa Composti derivati dell'acido beta-ossimino-propionico ad attivita' terapeutica,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
DK524686A (da) 1987-05-05
NO864379L (no) 1987-05-05
SG119194G (en) 1994-11-25
FI85372B (fi) 1991-12-31
IL80467A0 (en) 1987-01-30
FI864461A0 (fi) 1986-11-03
CY1864A (en) 1996-04-05
IE59775B1 (en) 1994-04-06
JPH0670014B2 (ja) 1994-09-07
NO864379D0 (no) 1986-11-03
IL80467A (en) 1990-11-05
DK115491A (da) 1991-06-14
DK164159B (da) 1992-05-18
IE862888L (en) 1987-05-04
CS382391A3 (en) 1992-04-15
LV5768A4 (lv) 1996-12-20
GR862634B (en) 1987-03-03
DK164159C (da) 1992-10-19
DK524686D0 (da) 1986-11-03
ATE86613T1 (de) 1993-03-15
JPH0368556A (ja) 1991-03-25
EP0221601B1 (en) 1993-03-10
DK169517B1 (da) 1994-11-21
NO170974B (no) 1992-09-28
FI85372C (fi) 1992-04-10
HK114595A (en) 1995-07-21
NO170974C (no) 1993-01-06
US4746671A (en) 1988-05-24
DK115491D0 (da) 1991-06-14
PT83667A (en) 1986-12-01
EP0221601A1 (en) 1987-05-13
DE3687945T2 (de) 1993-07-01
AU6482586A (en) 1987-05-07
PT83667B (pt) 1989-03-30
CA1298580C (en) 1992-04-07
DE3687945D1 (de) 1993-04-15
CA1319151C (en) 1993-06-15
FI864461A (fi) 1987-05-05
NZ218121A (en) 1989-08-29
AU587873B2 (en) 1989-08-31
ES2002015A6 (es) 1988-07-01

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