LV10446B - Novel tetrazole derivatives, method for their preparation and pharmaceutical compositions containing them - Google Patents

Novel tetrazole derivatives, method for their preparation and pharmaceutical compositions containing them Download PDF

Info

Publication number
LV10446B
LV10446B LVP-93-1285A LV931285A LV10446B LV 10446 B LV10446 B LV 10446B LV 931285 A LV931285 A LV 931285A LV 10446 B LV10446 B LV 10446B
Authority
LV
Latvia
Prior art keywords
formula
compound
methyl
well
group
Prior art date
Application number
LVP-93-1285A
Other languages
English (en)
Latvian (lv)
Other versions
LV10446A (lv
Inventor
Dieter Dr Binder
Josef Dr Weinberger
Andreas Dr Koch
Original Assignee
Chem Pharm Forsch Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Pharm Forsch Gmbh filed Critical Chem Pharm Forsch Gmbh
Publication of LV10446A publication Critical patent/LV10446A/xx
Publication of LV10446B publication Critical patent/LV10446B/lv

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Reinforced Plastic Materials (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
LVP-93-1285A 1991-01-31 1993-11-30 Novel tetrazole derivatives, method for their preparation and pharmaceutical compositions containing them LV10446B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0020991A AT395853B (de) 1991-01-31 1991-01-31 Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
LV10446A LV10446A (lv) 1995-02-20
LV10446B true LV10446B (en) 1995-10-20

Family

ID=3484393

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-93-1285A LV10446B (en) 1991-01-31 1993-11-30 Novel tetrazole derivatives, method for their preparation and pharmaceutical compositions containing them

Country Status (27)

Country Link
US (1) US5254574A (no)
EP (1) EP0497121B1 (no)
JP (1) JPH0641099A (no)
KR (1) KR920014802A (no)
CN (1) CN1034662C (no)
AT (2) AT395853B (no)
AU (1) AU642575B2 (no)
CA (1) CA2060387A1 (no)
CZ (1) CZ27592A3 (no)
DE (1) DE59208058D1 (no)
DK (1) DK0497121T3 (no)
EG (1) EG19886A (no)
ES (1) ES2100242T3 (no)
FI (1) FI920349A (no)
GR (1) GR3022686T3 (no)
HU (1) HUT62583A (no)
IE (1) IE914501A1 (no)
IL (1) IL100621A (no)
LT (1) LTIP1518A (no)
LV (1) LV10446B (no)
MY (1) MY106314A (no)
NO (1) NO179837C (no)
NZ (1) NZ241293A (no)
RU (1) RU2078764C1 (no)
SI (1) SI9210026A (no)
YU (1) YU48089B (no)
ZA (1) ZA92155B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1255802B (it) * 1992-08-07 1995-11-16 Luso Farmaco Inst Derivati imidazolici ad attivita' a ii antagonista
GB9507203D0 (en) * 1995-04-07 1995-05-31 Smithkline Beecham Plc Novel compounds
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
DE602004029373D1 (de) * 2003-08-27 2010-11-11 Zentiva Ks Verfahren zur entfernung der triphenylmethanschutzgruppe
US7803940B2 (en) * 2006-11-24 2010-09-28 Takeda Pharmaceutical Company Limited Heteromonocyclic compound or a salt thereof having strong antihypertensive action, insulin sensitizing activity and the like production thereof and use thereof for prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
AU2008261102B2 (en) 2007-06-04 2013-11-28 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2930674A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US9930928B2 (en) 2013-02-13 2018-04-03 Adidas Ag Sole for a shoe
DE102013202306B4 (de) 2013-02-13 2014-12-18 Adidas Ag Sohle für einen Schuh
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
USD776410S1 (en) 2013-04-12 2017-01-17 Adidas Ag Shoe
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
USD783264S1 (en) 2015-09-15 2017-04-11 Adidas Ag Shoe

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2860691D1 (en) * 1977-07-12 1981-08-13 Synthelabo 1,2,4-oxadiazol derivatives, their preparation and application in pharmaceutical compositions
US4771051A (en) * 1985-05-17 1988-09-13 A/S Ferrosan 3-substituted-4,5-dihydro-5-oxo imidazoquinazolines, their preparation, and their use in treating benzodiazepin receptor-related ailments
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
DE3627155A1 (de) * 1986-08-11 1988-02-18 Schering Ag Imidazol-derivate
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
CA1338238C (en) * 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
US5064825A (en) * 1989-06-01 1991-11-12 Merck & Co., Inc. Angiotensin ii antagonists
WO1991000277A1 (en) * 1989-06-30 1991-01-10 E.I. Du Pont De Nemours And Company Substituted imidazoles

Also Published As

Publication number Publication date
ATE149164T1 (de) 1997-03-15
CN1063689A (zh) 1992-08-19
AT395853B (de) 1993-03-25
LTIP1518A (en) 1995-06-26
ATA20991A (de) 1992-08-15
CN1034662C (zh) 1997-04-23
US5254574A (en) 1993-10-19
YU48089B (sh) 1997-01-08
FI920349A0 (fi) 1992-01-27
JPH0641099A (ja) 1994-02-15
RU2078764C1 (ru) 1997-05-10
MY106314A (en) 1995-04-29
SI9210026A (en) 1994-09-30
IL100621A (en) 1996-08-04
EP0497121B1 (de) 1997-02-26
IE914501A1 (en) 1992-07-29
IL100621A0 (en) 1992-09-06
CA2060387A1 (en) 1992-08-01
AU1063492A (en) 1992-08-06
FI920349A (fi) 1992-08-01
GR3022686T3 (en) 1997-05-31
HUT62583A (en) 1993-05-28
YU2692A (sh) 1994-11-15
NO920122L (no) 1992-08-03
AU642575B2 (en) 1993-10-21
NO179837B (no) 1996-09-16
CZ27592A3 (en) 1993-03-17
NZ241293A (en) 1993-04-28
KR920014802A (ko) 1992-08-25
ZA92155B (en) 1992-10-28
LV10446A (lv) 1995-02-20
ES2100242T3 (es) 1997-06-16
NO920122D0 (no) 1992-01-09
DE59208058D1 (de) 1997-04-03
DK0497121T3 (da) 1997-05-05
EP0497121A1 (de) 1992-08-05
EG19886A (en) 1996-05-31
HU9200292D0 (en) 1992-04-28
NO179837C (no) 1996-12-27

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