LU92114I2 - Ferumoxytol - Google Patents
FerumoxytolInfo
- Publication number
- LU92114I2 LU92114I2 LU92114C LU92114C LU92114I2 LU 92114 I2 LU92114 I2 LU 92114I2 LU 92114 C LU92114 C LU 92114C LU 92114 C LU92114 C LU 92114C LU 92114 I2 LU92114 I2 LU 92114I2
- Authority
- LU
- Luxembourg
- Prior art keywords
- compositions
- methods
- agent
- ferumoxytol
- agents
- Prior art date
Links
- 229940102709 ferumoxytol Drugs 0.000 title 1
- UCNNJGDEJXIUCC-UHFFFAOYSA-L hydroxy(oxo)iron;iron Chemical compound [Fe].O[Fe]=O.O[Fe]=O UCNNJGDEJXIUCC-UHFFFAOYSA-L 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 229920002307 Dextran Polymers 0.000 abstract 1
- 239000004606 Fillers/Extenders Substances 0.000 abstract 1
- 239000003173 antianemic agent Substances 0.000 abstract 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 239000012216 imaging agent Substances 0.000 abstract 1
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N iron oxide Inorganic materials [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 abstract 1
- 235000013980 iron oxide Nutrition 0.000 abstract 1
- VBMVTYDPPZVILR-UHFFFAOYSA-N iron(2+);oxygen(2-) Chemical class [O-2].[Fe+2] VBMVTYDPPZVILR-UHFFFAOYSA-N 0.000 abstract 1
- 238000002595 magnetic resonance imaging Methods 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
- A61K49/1851—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule
- A61K49/1863—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with an organic macromolecular compound, i.e. oligomeric, polymeric, dendrimeric organic molecule the organic macromolecular compound being a polysaccharide or derivative thereof, e.g. chitosan, chitin, cellulose, pectin, starch
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Hematology (AREA)
- Ceramic Engineering (AREA)
- Radiology & Medical Imaging (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Iron (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Cookers (AREA)
- Chemical Treatment Of Metals (AREA)
- Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12857999P | 1999-04-09 | 1999-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LU92114I2 true LU92114I2 (fr) | 2013-12-14 |
Family
ID=22436002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LU92114C LU92114I2 (fr) | 1999-04-09 | 2012-12-14 | Ferumoxytol |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6599498B1 (enExample) |
| EP (1) | EP1169062B1 (enExample) |
| JP (2) | JP5064612B2 (enExample) |
| AT (1) | ATE446108T1 (enExample) |
| CY (1) | CY1109527T1 (enExample) |
| DE (1) | DE60043188D1 (enExample) |
| DK (1) | DK1169062T3 (enExample) |
| ES (1) | ES2334555T3 (enExample) |
| LU (1) | LU92114I2 (enExample) |
| PT (1) | PT1169062E (enExample) |
| WO (1) | WO2000061191A2 (enExample) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7871597B2 (en) | 1999-04-09 | 2011-01-18 | Amag Pharmaceuticals, Inc. | Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents |
| US7169618B2 (en) * | 2000-06-28 | 2007-01-30 | Skold Technology | Magnetic particles and methods of producing coated magnetic particles |
| DE10046514A1 (de) * | 2000-09-15 | 2002-04-25 | Diagnostikforschung Inst | Verfahren zur bildlichen Darstellung und Diagnose von Thromben mittels Kernspintomographie unter Verwendung partikulärer Kontrastmittel |
| US6690962B2 (en) | 2000-09-15 | 2004-02-10 | Institut fur Diagnostikforshung GmbH | Process for graphic visualization and diagnosis of thrombi by means of nuclear spin tomography with use of particulate contrast media |
| WO2002046241A2 (en) * | 2000-12-07 | 2002-06-13 | Ad 'zdravlje' Farmaceutsko - Hemijska Industrija, Centar Za Istrazivanje I Razvoj | Polynuclear complex fe(iii) with pullulan oligomers, process of its obtaining, and pharmaceutical preparations on the basis of the complex |
| JP2004530513A (ja) * | 2001-06-29 | 2004-10-07 | ビオヴィトルム・アクチボラゲット | 大量オートクレーブ処理の方法 |
| WO2003057175A2 (en) | 2002-01-02 | 2003-07-17 | Visen Medical, Inc. | Amine functionalized superparamagnetic nanoparticles for the synthesis of bioconjugates and uses therefor |
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US20060018835A1 (en) * | 2004-04-02 | 2006-01-26 | General Electric Company | Nanoparticles with inorganic core and methods of using them |
| US20060014938A1 (en) * | 2004-07-14 | 2006-01-19 | Groman Ernest V | Stable aqueous colloidal lanthanide oxides |
| US20060140867A1 (en) * | 2004-12-28 | 2006-06-29 | Helfer Jeffrey L | Coated stent assembly and coating materials |
| CN101253416B (zh) | 2005-05-09 | 2011-08-24 | 通用医疗公司 | 基于水驰豫的传感器 |
| WO2007027843A2 (en) * | 2005-08-31 | 2007-03-08 | T2 Biosystems, Inc. | Nmr device for detection of analytes involving magnetic particles |
| US20070077313A1 (en) * | 2005-10-04 | 2007-04-05 | U.S. Pharmaceutical Corporation | Toleration iron supplement compositions |
| WO2007136413A2 (en) | 2005-12-22 | 2007-11-29 | Visen Medical, Inc. | Biocompatible fluorescent metal oxide nanoparticles |
| PT1973549T (pt) | 2006-01-06 | 2016-10-25 | Luitpold Pharm Inc | Métodos e composições para administração de ferro |
| AU2016205002C1 (en) * | 2006-01-06 | 2020-09-24 | Vifor (International) Ag | Methods and compositions for administration of iron |
| AU2013206429B2 (en) * | 2006-01-06 | 2016-04-28 | Vifor (International) Ag | Methods and compositions for administration of iron |
| NO329127B1 (no) * | 2006-09-12 | 2010-08-30 | Epitarget As | Sporbart partikulaert materiale for legemiddelavlevering omfattende et matriseeller membranmateriale, et legemiddel, og et T1- og et T2*- magnetisk resonanskontrastmiddel |
| EP2084550A1 (en) | 2006-11-08 | 2009-08-05 | T2 Biosystems, Inc. | Nmr systems for in vivo detection of analytes |
| US9375495B2 (en) * | 2007-04-12 | 2016-06-28 | Industry-Academic Cooperation Foundation, Yonsei University | Magnetic resonance imaging contrast agents comprising zinc-containing magnetic metal oxide nanoparticles |
| US20120003160A1 (en) * | 2007-06-29 | 2012-01-05 | Amag Pharmaceuticals, Inc. | Macrophage-Enhanced MRI (MEMRI) in a Single Imaging Session |
| EP2201398A1 (en) | 2007-09-28 | 2010-06-30 | T2 Biosystems, Inc. | Nmr diagnostics by means of a plastic sample container |
| US8519708B2 (en) * | 2007-11-06 | 2013-08-27 | T2 Biosystems, Inc. | Small magnet and RF coil for magnetic resonance relaxometry |
| JP2011503232A (ja) | 2007-11-20 | 2011-01-27 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 免疫応答の調節 |
| WO2009127045A1 (en) * | 2008-04-16 | 2009-10-22 | Stemcell Technologies Inc. | Magnetic particles |
| AU2009308841B2 (en) | 2008-10-29 | 2014-07-17 | T2 Biosystems, Inc. | NMR detection of coagulation time |
| US8840868B2 (en) | 2009-02-04 | 2014-09-23 | The Regents Of The University Of Colorado, A Body Corporate | Non-invasive detection of complement-mediated inflammation using CR2-targeted nanoparticles |
| JP5841044B2 (ja) | 2009-03-23 | 2016-01-06 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. | 複合糖質ワクチン |
| BRPI0924653B8 (pt) | 2009-03-25 | 2021-05-25 | Pharmacosmos Holding As | composto de ferro-oligossacarídeo, composição e uso de deste composto |
| WO2011005496A2 (en) | 2009-06-22 | 2011-01-13 | Massachusetts Eye & Ear Infirmary | Islet1 (isl1) and hearing loss |
| WO2011150212A2 (en) | 2010-05-26 | 2011-12-01 | The General Hospital Corporation | Magnetic nanoparticles |
| US9636423B2 (en) | 2010-06-02 | 2017-05-02 | The General Hospital Corporation | Optical sensor conjugates for detecting reactive oxygen and/or reactive nitrogen species in vivo |
| CN106176808A (zh) | 2010-10-19 | 2016-12-07 | 长春纳米生技公司 | 金属离子纳米簇组合物 |
| CA3155334A1 (en) | 2010-10-22 | 2012-04-26 | T2 Biosystems, Inc. | NMR SYSTEMS AND METHODS FOR RAPID ANALYTE DETECTION |
| US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| US8409807B2 (en) | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| CN102086232B (zh) * | 2010-12-15 | 2012-05-23 | 吕辉 | 一种多糖铁的制备方法 |
| US9599627B2 (en) | 2011-07-13 | 2017-03-21 | T2 Biosystems, Inc. | NMR methods for monitoring blood clot formation |
| BR112014002986A2 (pt) | 2011-08-10 | 2017-06-13 | Adocia | composição sob a forma de uma solução injetável, e formulação de dose única |
| WO2013043858A1 (en) | 2011-09-21 | 2013-03-28 | T2 Biosystems, Inc. | Nmr methods for endotoxin analysis |
| WO2013078332A1 (en) | 2011-11-23 | 2013-05-30 | The General Hospital Corporation | Analyte detection using magnetic hall effect |
| WO2013104861A1 (fr) | 2012-01-09 | 2013-07-18 | Adocia | Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide substitue |
| EP2647389A1 (en) | 2012-04-04 | 2013-10-09 | Charité - Universitätsmedizin Berlin | Magnetic nanoparticle dispersion, its preparation and diagnostic and therapeutic use |
| WO2013158281A1 (en) | 2012-04-20 | 2013-10-24 | T2 Biosystems, Inc. | Compositions and methods for detection of candida species |
| US10274490B2 (en) | 2012-06-12 | 2019-04-30 | The General Hospital Corporation | Magnetic labeling of bacteria |
| EP2864051B1 (en) | 2012-06-25 | 2020-09-23 | The General Hospital Corporation | Sorting particles using high gradient magnetic fields |
| US9675640B2 (en) * | 2012-08-07 | 2017-06-13 | Southwest Research Institute | Magnetic calcium phosphate nanoparticles, applications and methods of preparation thereof |
| US20150314003A2 (en) | 2012-08-09 | 2015-11-05 | Adocia | Injectable solution at ph 7 comprising at least one basal insulin the isoelectric point of which is between 5.8 and 8.5 and a hydrophobized anionic polymer |
| JP2016500443A (ja) | 2012-12-07 | 2016-01-12 | ティー2 バイオシステムズ,インコーポレーテッド | 強固な血餅形成をモニタリングするための方法 |
| MX359794B (es) | 2013-03-15 | 2018-10-10 | Intrinsic Lifesciences Llc | Anticuerpos anti-hepcidina y usos de los mismos. |
| US9370202B2 (en) | 2013-03-15 | 2016-06-21 | LG Bionano, LLC | Encapsulated metal ion nanoclusters |
| EP3560591B1 (en) | 2013-10-18 | 2021-02-17 | The General Hospital Corporation | Microfluidic sorting using high gradient magnetic fields |
| US9566216B2 (en) | 2013-11-18 | 2017-02-14 | Southwest Research Institute | Bone cements containing magnetic calcium phosphate nanoparticles |
| KR20150078375A (ko) | 2013-12-30 | 2015-07-08 | 한화케미칼 주식회사 | 철산화물 나노입자를 포함하는 철결핍증의 예방 또는 치료용 약학 조성물 |
| US10898581B2 (en) | 2014-01-16 | 2021-01-26 | The Brigham And Women's Hospital, Inc. | Targeted delivery of immunoregulatory drugs |
| TWI689310B (zh) | 2014-07-11 | 2020-04-01 | 巨生生醫股份有限公司 | 治療鐵缺乏症之方法 |
| EP3197915A4 (en) | 2014-09-22 | 2018-12-19 | Intrinsic Lifesciences LLC | Humanized anti-hepcidin antibodies and uses thereof |
| WO2016073481A1 (en) | 2014-11-03 | 2016-05-12 | The General Hospital Corporation | Sorting particles in a microfluidic device |
| CN105597105B (zh) * | 2014-11-19 | 2020-03-10 | 连云港润众制药有限公司 | 一种菲立莫妥的制备方法 |
| CA2980730A1 (en) | 2015-03-23 | 2016-09-29 | The Brigham And Women's Hospital, Inc. | Tolerogenic nanoparticles for treating diabetes mellitus |
| US10258647B2 (en) | 2015-09-01 | 2019-04-16 | Particle Dynamics International, Llc | Iron-polysaccharide complexes and methods for the preparation thereof |
| CA3011901A1 (en) | 2016-01-21 | 2017-07-27 | T2 Biosystems, Inc. | Nmr methods and systems for the rapid detection of bacteria |
| CN105708805A (zh) * | 2016-01-28 | 2016-06-29 | 山西普德药业股份有限公司 | 一种还原型羧烷基葡聚糖铁及其制备方法 |
| CN105616372A (zh) * | 2016-01-28 | 2016-06-01 | 山西普德药业股份有限公司 | 一种还原型羧烷基葡聚糖铁片剂 |
| CN105708792A (zh) * | 2016-01-28 | 2016-06-29 | 山西普德药业股份有限公司 | 一种还原型羧烷基葡聚糖铁注射液及其制备方法 |
| TR201703251A2 (tr) | 2017-03-03 | 2017-07-21 | Berna Buelbuel | Kansizliğin transdermal yoldan tedavi̇si̇nde kullanilacak demi̇r oksi̇t nanokri̇stalleri̇ i̇çeren solüsyon |
| CN108403716B (zh) * | 2018-06-25 | 2021-11-05 | 博瑞生物医药(苏州)股份有限公司 | 一种超顺磁氧化铁的制备方法 |
| SG11202108560RA (en) | 2019-02-13 | 2021-09-29 | Brigham & Womens Hospital Inc | Anti-peripheral lymph node addressin antibodies and uses thereof |
| WO2025043086A1 (en) | 2023-08-22 | 2025-02-27 | Navinta, Llc | An improved process for the preparation of solid ferumoxytol |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2885393A (en) * | 1956-02-24 | 1959-05-05 | R K Laros Company | Dextran-iron complex and process for making same |
| US2862920A (en) * | 1956-06-07 | 1958-12-02 | Ohio Commw Eng Co | Ferrous carboxymethyl dextran |
| US3000872A (en) * | 1956-06-15 | 1961-09-19 | Ohio Commw Eng Co | Preparation of carboxymethyl dextran-iron complexes |
| US2856398A (en) * | 1956-06-15 | 1958-10-14 | Ohio Commw Eng Co | Carboxymethyl dextran-iron complexes |
| US2856366A (en) * | 1956-07-30 | 1958-10-14 | Ohio Commw Eng Co | Stable alkaline metal solutions containing carboxymethyl dextran |
| US3151107A (en) * | 1960-12-22 | 1964-09-29 | Central Pharmacal Company | Water-soluble iron complexes of carboxymethyl dextran |
| GB1019513A (en) * | 1961-08-07 | 1966-02-09 | Chemicals Inc | Iron dextran complexes |
| US3234209A (en) * | 1963-09-13 | 1966-02-08 | Chemicals Inc | Process for making iron hydrogenated dextran |
| JPS5913521B2 (ja) * | 1975-06-19 | 1984-03-30 | メイトウサンギヨウ カブシキガイシヤ | 磁性酸化鉄・デキストラン複合体の製造法 |
| US4180567A (en) * | 1977-09-02 | 1979-12-25 | Pharmachem Corporation | Iron preparations and methods of making and administering the same |
| US4452773A (en) * | 1982-04-05 | 1984-06-05 | Canadian Patents And Development Limited | Magnetic iron-dextran microspheres |
| US5076950A (en) | 1985-12-20 | 1991-12-31 | Syntex (U.S.A.) Inc. | Magnetic composition for particle separation |
| CA1304006C (en) | 1985-12-20 | 1992-06-23 | Edwin F. Ullman | Particle separation method |
| US5055288A (en) | 1987-06-26 | 1991-10-08 | Advanced Magnetics, Inc. | Vascular magnetic imaging method and agent comprising biodegradeable superparamagnetic metal oxides |
| US5262176A (en) | 1986-07-03 | 1993-11-16 | Advanced Magnetics, Inc. | Synthesis of polysaccharide covered superparamagnetic oxide colloids |
| US4770183A (en) | 1986-07-03 | 1988-09-13 | Advanced Magnetics Incorporated | Biologically degradable superparamagnetic particles for use as nuclear magnetic resonance imaging agents |
| US5102652A (en) | 1986-07-03 | 1992-04-07 | Advanced Magnetics Inc. | Low molecular weight carbohydrates as additives to stabilize metal oxide compositions |
| US4827945A (en) * | 1986-07-03 | 1989-05-09 | Advanced Magnetics, Incorporated | Biologically degradable superparamagnetic materials for use in clinical applications |
| US5160726A (en) | 1990-02-15 | 1992-11-03 | Advanced Magnetics Inc. | Filter sterilization for production of colloidal, superparamagnetic MR contrast agents |
| GB8808305D0 (en) * | 1988-04-08 | 1988-05-11 | Nycomed As | Compositions |
| JP2726520B2 (ja) | 1989-10-20 | 1998-03-11 | 名糖産業株式会社 | 有機磁性複合体 |
| WO1991009678A1 (en) | 1989-12-22 | 1991-07-11 | Omni Quest Corporation | Organo-metallic coated particles for use in separations |
| GB9416767D0 (en) * | 1994-08-18 | 1994-10-12 | Nycomed Innovation Ab | Compositions |
| EP0783325B2 (en) | 1994-09-27 | 2004-03-31 | Amersham Health AS | Contrast agent |
| US6165378A (en) * | 1996-08-30 | 2000-12-26 | Meito Sangyo Kabushiki Kaisha | Polysaccharide derivative/magnetic metal oxide composite |
| DK172860B1 (da) * | 1998-03-25 | 1999-08-16 | Pharmacosmos Holding As | Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman |
| DK173138B1 (da) | 1998-11-20 | 2000-02-07 | Pharmacosmos Holding As | Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma |
-
2000
- 2000-03-08 AT AT00914867T patent/ATE446108T1/de active
- 2000-03-08 ES ES00914867T patent/ES2334555T3/es not_active Expired - Lifetime
- 2000-03-08 WO PCT/US2000/006047 patent/WO2000061191A2/en not_active Ceased
- 2000-03-08 PT PT00914867T patent/PT1169062E/pt unknown
- 2000-03-08 DE DE60043188T patent/DE60043188D1/de not_active Expired - Lifetime
- 2000-03-08 JP JP2000610523A patent/JP5064612B2/ja not_active Expired - Fee Related
- 2000-03-08 US US09/521,264 patent/US6599498B1/en not_active Expired - Lifetime
- 2000-03-08 EP EP00914867A patent/EP1169062B1/en not_active Revoked
- 2000-03-08 DK DK00914867.7T patent/DK1169062T3/da active
-
2003
- 2003-03-11 US US10/386,394 patent/US7553479B2/en not_active Expired - Fee Related
-
2009
- 2009-12-01 CY CY20091101262T patent/CY1109527T1/el unknown
-
2010
- 2010-12-09 JP JP2010275172A patent/JP2011046752A/ja not_active Withdrawn
-
2012
- 2012-12-14 LU LU92114C patent/LU92114I2/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE446108T1 (de) | 2009-11-15 |
| US7553479B2 (en) | 2009-06-30 |
| PT1169062E (pt) | 2009-12-17 |
| DE60043188D1 (de) | 2009-12-03 |
| EP1169062A2 (en) | 2002-01-09 |
| JP2011046752A (ja) | 2011-03-10 |
| EP1169062B1 (en) | 2009-10-21 |
| ES2334555T3 (es) | 2010-03-12 |
| DK1169062T3 (da) | 2010-01-25 |
| WO2000061191A9 (en) | 2001-06-21 |
| JP5064612B2 (ja) | 2012-10-31 |
| CY1109527T1 (el) | 2014-08-13 |
| WO2000061191A2 (en) | 2000-10-19 |
| US6599498B1 (en) | 2003-07-29 |
| US20030225033A1 (en) | 2003-12-04 |
| WO2000061191A3 (en) | 2001-05-25 |
| JP2002541218A (ja) | 2002-12-03 |
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