LU86600A1 - Produits d'echange entre un aminodisulfure et un thiol - Google Patents

Produits d'echange entre un aminodisulfure et un thiol Download PDF

Info

Publication number
LU86600A1
LU86600A1 LU86600A LU86600A LU86600A1 LU 86600 A1 LU86600 A1 LU 86600A1 LU 86600 A LU86600 A LU 86600A LU 86600 A LU86600 A LU 86600A LU 86600 A1 LU86600 A1 LU 86600A1
Authority
LU
Luxembourg
Prior art keywords
compound
identified
compound according
amino
substituted
Prior art date
Application number
LU86600A
Other languages
English (en)
French (fr)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of LU86600A1 publication Critical patent/LU86600A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LU86600A 1985-09-23 1986-09-22 Produits d'echange entre un aminodisulfure et un thiol LU86600A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78107685 1985-09-23
US06/781,076 US4866180A (en) 1984-02-24 1985-09-23 Amino disulfide thiol exchange products

Publications (1)

Publication Number Publication Date
LU86600A1 true LU86600A1 (fr) 1987-04-02

Family

ID=25121607

Family Applications (1)

Application Number Title Priority Date Filing Date
LU86600A LU86600A1 (fr) 1985-09-23 1986-09-22 Produits d'echange entre un aminodisulfure et un thiol

Country Status (10)

Country Link
US (1) US4866180A (es)
KR (1) KR940006629B1 (es)
AT (1) AT394725B (es)
CA (1) CA1288106C (es)
ES (1) ES2001978A6 (es)
FI (1) FI863776A (es)
GR (1) GR862416B (es)
LU (1) LU86600A1 (es)
PT (1) PT83418B (es)
ZA (1) ZA866297B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175303A (en) * 1990-03-08 1992-12-29 Bristol-Myers Squibb Company Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane
US5629427A (en) * 1993-08-26 1997-05-13 Peterson; Dwight M. 2,7-diaminomitosene analogues
DE60231868D1 (de) 2001-04-24 2009-05-20 Purdue Research Foundation Folat-mimetika und deren folatrezeptorbindende konjugate
EP1504010B1 (en) * 2002-05-15 2009-03-25 Endocyte, Inc. Vitamin-mitomycin conjugates
JP5576007B2 (ja) 2003-01-27 2014-08-20 エンドサイト・インコーポレイテッド ビタミン受容体結合性薬剤送達結合体
EP1789391B1 (en) * 2004-07-23 2017-06-28 Endocyte, Inc. Bivalent linkers and conjugates thereof
EP1863816B1 (en) * 2005-03-16 2014-06-25 Endocyte, Inc. Synthesis and purification of pteroic acid and conjugates thereof
BRPI0615354A2 (pt) * 2005-08-19 2011-05-17 Endocyte Inc conjugado de liberação de fármaco de ligação de receptor, composição farmacêutica que o compreende, bem como seu uso
EP2382995A3 (en) * 2005-08-19 2013-09-25 Endocyte, Inc. Ligand conjugates of Vinca alkaloids, analogs and derivatives
US20100104626A1 (en) * 2007-02-16 2010-04-29 Endocyte, Inc. Methods and compositions for treating and diagnosing kidney disease
NZ599239A (en) * 2007-03-14 2013-10-25 Endocyte Inc Binding ligand linked drug delivery conjugates of tubulysins
US9877965B2 (en) 2007-06-25 2018-01-30 Endocyte, Inc. Vitamin receptor drug delivery conjugates for treating inflammation
CA2690943A1 (en) 2007-06-25 2008-12-31 Endocyte, Inc. Conjugates containing hydrophilic spacer linkers
CA2703491C (en) * 2007-10-25 2017-06-13 Endocyte, Inc. Tubulysins and processes for preparing
US10080805B2 (en) 2012-02-24 2018-09-25 Purdue Research Foundation Cholecystokinin B receptor targeting for imaging and therapy
US20140080175A1 (en) 2012-03-29 2014-03-20 Endocyte, Inc. Processes for preparing tubulysin derivatives and conjugates thereof
EP2908818A4 (en) 2012-10-16 2016-07-13 Endocyte Inc CONJUGATES OF DRUG DELIVERY CONTAINING ARTIFICIAL AMINO ACIDS AND METHODS OF USE

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660578A (en) * 1957-04-06 1972-05-02 Kyowa Hakko Kogyo Kk Mitomycin c
NL129868C (es) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) * 1964-08-25 1969-01-07 Kyowa Hakko Kogyo Kk 7-substituted mitomycin a
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
GB2093643A (en) * 1981-02-17 1982-09-02 Standard Telephones Cables Ltd DC-to-DC converter
EP0116208B1 (en) * 1982-12-07 1988-03-30 Kyowa Hakko Kogyo Co., Ltd. Mitomycin analogues
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体,その製造法および抗腫瘍剤

Also Published As

Publication number Publication date
PT83418A (en) 1986-10-01
FI863776A (fi) 1987-03-24
CA1288106C (en) 1991-08-27
ZA866297B (en) 1987-04-29
GR862416B (en) 1987-01-26
ATA254886A (de) 1991-11-15
KR870003111A (ko) 1987-04-15
KR940006629B1 (ko) 1994-07-23
FI863776A0 (fi) 1986-09-18
AT394725B (de) 1992-06-10
PT83418B (pt) 1989-05-12
ES2001978A6 (es) 1988-07-01
US4866180A (en) 1989-09-12

Similar Documents

Publication Publication Date Title
LU86600A1 (fr) Produits d'echange entre un aminodisulfure et un thiol
EP0116208B1 (en) Mitomycin analogues
EP0280741B1 (en) Mitomycin derivatives
EP2404921B1 (en) SALTS OF TETRAHYDROIMIDAZO[1,5-a]PYRAZINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USE THEREOF
US6306849B1 (en) Selected derivatives of K-252a
EP0313874B1 (en) Disulfur analogs of LL-E33288 antitumor agents
FR2528048A1 (fr) Amidines de la famille des mitosanes et leur application pharmacologique
JPH0597853A (ja) Dc−89誘導体の臭化水素酸塩
KR890001488B1 (ko) 미토마이신 c 유도체의 제조방법
US4814445A (en) Process for preparing mitomycin analogs
LU85711A1 (fr) Acylaminomitosanes
CA1291293C (en) Substituted 7-oxomitosanes
JP2991348B2 (ja) 7−(ジフェニルメチル)オキシ−9a−メトキシマイトサン並びにその製造及び使用
FR2517680A1 (fr) Derives n-(vinblastinoyl-23) d'acides amines, leur preparation et leur application therapeutique
BE899380A (fr) Aminodisulfures.
US4927943A (en) Substituted 7-oxomitosanes
Giandinoto et al. A facile preparation of some novel class II mesoionic xanthine acyclonucleosides
US5106840A (en) Method of preparing n-oxo-tetrahydro-beta-carbolines
LU86411A1 (fr) Procede de preparation de derives n7-amidino-substitutes de la mitomycine c.
US5318975A (en) 5-pyrimdineamine derivatives
EP0272063B1 (en) Mitomycin derivatives
EP0294828B1 (en) Mitomycin analogs, a process for preparing them and pharmaceutical compositions
BE896963A (fr) Amidines
EP0412015B1 (fr) Nouveaux dérivés N-(vincristinoyl-23) et N-(noranhydro-5' vinblastinoyl-23) d'acide amino-1 méthylphosphonique, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
CA1204770A (en) Fluorinated diaminoalkene derivatives