LU85199A1 - Analogues de mitomycine - Google Patents

Analogues de mitomycine Download PDF

Info

Publication number
LU85199A1
LU85199A1 LU85199A LU85199A LU85199A1 LU 85199 A1 LU85199 A1 LU 85199A1 LU 85199 A LU85199 A LU 85199A LU 85199 A LU85199 A LU 85199A LU 85199 A1 LU85199 A1 LU 85199A1
Authority
LU
Luxembourg
Prior art keywords
methyl
carbamate
dione
azirino
hexahydro
Prior art date
Application number
LU85199A
Other languages
English (en)
French (fr)
Inventor
William A Remers
Original Assignee
University Patents Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Patents Inc filed Critical University Patents Inc
Publication of LU85199A1 publication Critical patent/LU85199A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU85199A 1983-02-07 1984-02-07 Analogues de mitomycine LU85199A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46461283A 1983-02-07 1983-02-07
US46461283 1983-02-07

Publications (1)

Publication Number Publication Date
LU85199A1 true LU85199A1 (fr) 1984-05-30

Family

ID=23844605

Family Applications (1)

Application Number Title Priority Date Filing Date
LU85199A LU85199A1 (fr) 1983-02-07 1984-02-07 Analogues de mitomycine

Country Status (29)

Country Link
JP (1) JPS59152384A (no)
KR (1) KR900006854B1 (no)
AT (1) AT385509B (no)
AU (1) AU571193B2 (no)
BE (1) BE898856A (no)
CA (1) CA1252789A (no)
CH (1) CH658658A5 (no)
DD (1) DD233844A5 (no)
DE (1) DE3403922A1 (no)
DK (1) DK161890C (no)
ES (1) ES8607305A1 (no)
FI (1) FI80698C (no)
FR (1) FR2540500B1 (no)
GB (1) GB2134514B (no)
GR (1) GR81455B (no)
HU (1) HU190236B (no)
IE (1) IE56814B1 (no)
IL (1) IL70897A (no)
IT (1) IT1178855B (no)
LU (1) LU85199A1 (no)
NL (1) NL8400338A (no)
NO (1) NO161374C (no)
NZ (1) NZ206932A (no)
OA (1) OA07654A (no)
PH (1) PH20249A (no)
PT (1) PT78067B (no)
SE (1) SE461982B (no)
YU (1) YU44984B (no)
ZA (1) ZA84788B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
CA1282069C (en) * 1985-09-12 1991-03-26 Damon L. Meyer Antibody complexes of hapten-modified diagnostic or therapeutic agents
JPS63150282A (ja) * 1986-12-13 1988-06-22 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPS63246379A (ja) * 1987-03-31 1988-10-13 Kyowa Hakko Kogyo Co Ltd 7−n,8−n−エチレンマイトマイシン8−イミン類
EP0485904B1 (en) * 1990-11-13 1997-08-20 Kyowa Hakko Kogyo Co., Ltd. Mitomycin derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
JPS5686184A (en) * 1979-12-17 1981-07-13 Kyowa Hakko Kogyo Co Ltd Novel mitomycin c derivative
NZ199617A (en) * 1981-05-15 1985-08-30 University Patents Inc Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes

Also Published As

Publication number Publication date
DE3403922A1 (de) 1984-08-09
YU21784A (en) 1986-10-31
PT78067A (en) 1984-03-01
GB2134514B (en) 1987-04-01
AU2407384A (en) 1984-08-16
GB2134514A (en) 1984-08-15
OA07654A (fr) 1985-05-23
DD233844A5 (de) 1986-03-12
JPS59152384A (ja) 1984-08-31
FR2540500B1 (fr) 1987-07-17
KR840007726A (ko) 1984-12-10
DK161890B (da) 1991-08-26
NZ206932A (en) 1987-08-31
FI80698C (fi) 1990-07-10
SE8400628D0 (sv) 1984-02-07
DK52484D0 (da) 1984-02-06
ZA84788B (en) 1984-09-26
ES8607305A1 (es) 1986-05-16
IL70897A (en) 1989-01-31
NO840433L (no) 1984-08-08
BE898856A (fr) 1984-05-30
GR81455B (no) 1984-12-11
DK52484A (da) 1984-08-08
ES529478A0 (es) 1986-05-16
FI80698B (fi) 1990-03-30
ATA37684A (de) 1987-09-15
HU190236B (en) 1986-08-28
SE461982B (sv) 1990-04-23
FI840502A (fi) 1984-08-08
AU571193B2 (en) 1988-04-14
YU44984B (en) 1991-06-30
PT78067B (en) 1986-03-20
NO161374C (no) 1989-08-09
CA1252789A (en) 1989-04-18
NO161374B (no) 1989-05-02
IE56814B1 (en) 1991-12-18
IT1178855B (it) 1987-09-16
AT385509B (de) 1988-04-11
FR2540500A1 (fr) 1984-08-10
GB8402233D0 (en) 1984-02-29
DK161890C (da) 1992-02-03
IE840272L (en) 1984-08-07
NL8400338A (nl) 1984-09-03
SE8400628L (sv) 1984-08-08
PH20249A (en) 1986-11-10
IL70897A0 (en) 1984-05-31
IT8467113A0 (it) 1984-02-07
FI840502A0 (fi) 1984-02-07
KR900006854B1 (ko) 1990-09-22
CH658658A5 (de) 1986-11-28

Similar Documents

Publication Publication Date Title
DE60210093T2 (de) Beta-amino-tetrahydroimidazo(1,2-a)pyrazine und -tetrahydrotriazolo(4,3-a)pyrazine als dipeptidyl peptidase inhibitoren zur behandlung oder prevention von diabetes
EP0124502B1 (fr) Nouveaux conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques contenant ces conjugués
EP2406263B1 (fr) Derivés de pyrazolo[1,5-a]-1,3,5-triazines, leur preparation et leur application en thérapeutique
LU84144A1 (fr) Analogues de la mitomycine
LU85199A1 (fr) Analogues de mitomycine
FR2580642A1 (fr) 5-pyrimidinecarboxamides et traitement de la leucemie et des tumeurs en les utilisant
FR2499577A1 (fr) Nouvelles 1-(2-chloroethyl)-1-nitrosourees-3-substituees par un reste de sucre, utiles notamment comme agents antitumoraux et leur procede de preparation
JPH02502543A (ja) 新規6置換マイトマイシン類似体
US4746746A (en) Mitomycin analogs
LU86059A1 (fr) Nouveaux analogues 6-substitues de la mitomycine
EP1001944B1 (fr) Derives de pyrazine, leur preparation et les medicaments les contenant
RU2768451C1 (ru) Селективный антагонист рецепторов типа A2A
US4617389A (en) Mitomycin analogs
CA2463923A1 (fr) Nouveaux derives d'hydroxyalkyle indolocarbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB2223753A (en) Piperazine derivatives
Kundu et al. N-Alkylated derivatives of 5-fluorouracil
US5863921A (en) Purine and guanine derivatives
LU86411A1 (fr) Procede de preparation de derives n7-amidino-substitutes de la mitomycine c.
CA1204770A (en) Fluorinated diaminoalkene derivatives
BE1001262A4 (fr) Procede en vue de provoquer la regression de la leucemie et l'inhibition de la croissance des tumeurs chez les mammiferes.
KR920002792B1 (ko) 아실화 엔아미드 화합물의 제조 방법
EP0408384A1 (en) N,N'-dicarboxymethyl, N,N'-dicarbamoylmethyl diaminoalkane derivatives and their use in pharmaceutical compositions.
LU87274A1 (fr) Procede en vue de provoquer la regression de la leucemie et l'inhibition de la croissance des tumeurs chez les mammiferes
FR2582649A1 (fr) Derives methyles de bis 7h pyridocarbazoles methyles et compositions pharmaceutiques les contenant
JPS58185521A (ja) 抗腫瘍剤