LU80566A1 - 4-(di-n-propyl)amino-1,3,4,5-tetrahydrobenzo(cd)indole et son utilisation therapeutique - Google Patents

4-(di-n-propyl)amino-1,3,4,5-tetrahydrobenzo(cd)indole et son utilisation therapeutique

Info

Publication number
LU80566A1
LU80566A1 LU80566A LU80566A LU80566A1 LU 80566 A1 LU80566 A1 LU 80566A1 LU 80566 A LU80566 A LU 80566A LU 80566 A LU80566 A LU 80566A LU 80566 A1 LU80566 A1 LU 80566A1
Authority
LU
Luxembourg
Prior art keywords
tetrahydrobenzo
indole
propyl
amino
therapeutic use
Prior art date
Application number
LU80566A
Other languages
English (en)
French (fr)
Inventor
E Kornfeld
N Bach
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of LU80566A1 publication Critical patent/LU80566A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/90Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LU80566A 1977-11-25 1978-11-23 4-(di-n-propyl)amino-1,3,4,5-tetrahydrobenzo(cd)indole et son utilisation therapeutique LU80566A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/854,878 US4110339A (en) 1977-11-25 1977-11-25 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole

Publications (1)

Publication Number Publication Date
LU80566A1 true LU80566A1 (fr) 1979-03-22

Family

ID=25319760

Family Applications (1)

Application Number Title Priority Date Filing Date
LU80566A LU80566A1 (fr) 1977-11-25 1978-11-23 4-(di-n-propyl)amino-1,3,4,5-tetrahydrobenzo(cd)indole et son utilisation therapeutique

Country Status (16)

Country Link
US (1) US4110339A (es)
EP (1) EP0002570B1 (es)
JP (1) JPS5481263A (es)
AR (1) AR219565A1 (es)
BE (1) BE872152A (es)
CA (1) CA1108155A (es)
CH (1) CH639070A5 (es)
DE (1) DE2861487D1 (es)
DK (1) DK524778A (es)
FR (1) FR2409984A1 (es)
GB (1) GB2008587B (es)
HU (1) HU176955B (es)
IE (1) IE47591B1 (es)
IL (1) IL56016A (es)
IT (1) IT1101439B (es)
LU (1) LU80566A1 (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4501900A (en) * 1979-11-23 1985-02-26 Merck & Co., Inc. Amino substituted tetrahydrobenzindoles
US4282240A (en) * 1979-11-23 1981-08-04 Merck & Co., Inc. Amino substituted tetrahydrobenzindoles
FR2471373A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux derives de la benzindolamine, leurs sels, procede de preparation, application a titre de medicaments et composition les renfermant
EP0034989B1 (fr) * 1980-02-26 1983-10-05 Roussel-Uclaf Nouveaux dérivés du cycloheptindolol et leurs sels avec les acides, leur préparation, leur application comme médicaments et les compositions les renfermant
FR2493842A1 (fr) * 1980-11-07 1982-05-14 Roussel Uclaf Nouveaux derives de l'aminocycloheptindole, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant
US4454150A (en) * 1981-10-19 1984-06-12 Ayerst, Mckenna & Harrison Inc. 6,7,8,9-Tetrahydro-3H-benz(e)indol-7-amines and a method of dopamine receptor stimulation therewith
CA1159459A (en) * 1980-12-11 1983-12-27 Andre A. Asselin 6,7,8,9-tetrahydro-3h-benz¬e| indolamine derivatives
US4510157A (en) * 1982-12-27 1985-04-09 Ayerst, Mckenna & Harrison, Inc. 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives
US4470990A (en) * 1983-03-14 1984-09-11 Ayerst, Mckenna & Harrison Inc. 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants
DE3346573A1 (de) * 1983-12-23 1985-07-04 Troponwerke GmbH & Co KG, 5000 Köln 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
US4983622A (en) * 1984-02-06 1991-01-08 Eli Lilly And Company 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
US5026869A (en) * 1984-02-06 1991-06-25 Eli Lilly And Company 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
US5273975A (en) * 1989-06-09 1993-12-28 The Upjohn Company Heterocyclic amines having central nervous system activity
TW219933B (es) * 1990-02-26 1994-02-01 Lilly Co Eli
IL97309A (en) * 1990-02-26 1996-11-14 Lilly Co Eli Intermediates for hexahydrobenz] [DC indoles and a process for making their pure enantiomers
US5212319A (en) * 1990-02-26 1993-05-18 Eli Lilly And Company Intermediates to 4-amino-hexahydrobenz[cd]indoles and processes therefor
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
US5229410A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5656653A (en) * 1991-03-28 1997-08-12 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz[cd]indoles
US5347013A (en) * 1991-03-28 1994-09-13 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5244911A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
ES2149869T3 (es) * 1993-03-25 2000-11-16 Upjohn Co Derivados de indol sustituidos por formil o ciano con actividad dopominergica.
CZ285762B6 (cs) * 1993-06-10 1999-11-17 Eli Lilly And Company Farmaceutický prostředek vhodný pro prevenci dávení a zvracení a pro ošetřování sexuální dysfunkce savců a jeho použití
CN1043574C (zh) 1993-07-27 1999-06-09 法玛西雅厄普约翰美国公司 具有中枢神经系统活性的杂环胺
US7074927B2 (en) * 1999-05-13 2006-07-11 Pharmacia & Upjohn Company Heterocyclic amines having central nervous system activity
JP6518355B2 (ja) * 2018-02-06 2019-05-22 株式会社ネオス フッ素系重合体及びこれを含有する表面処理剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200130A (en) * 1963-08-27 1965-08-10 Upjohn Co Derivatives of 1, 3, 4, 5-tetrahydro-benz[cd]indoles

Also Published As

Publication number Publication date
AR219565A1 (es) 1980-08-29
JPS6160830B2 (es) 1986-12-23
FR2409984B1 (es) 1981-11-27
GB2008587B (en) 1982-02-17
IL56016A0 (en) 1979-01-31
JPS5481263A (en) 1979-06-28
HU176955B (hu) 1981-06-28
US4110339A (en) 1978-08-29
BE872152A (fr) 1979-05-21
CA1108155A (en) 1981-09-01
IE47591B1 (en) 1984-05-02
IT7830205A0 (it) 1978-11-24
EP0002570B1 (en) 1981-12-30
DK524778A (da) 1979-05-26
IL56016A (en) 1981-11-30
GB2008587A (en) 1979-06-06
IE782325L (en) 1979-05-25
DE2861487D1 (en) 1982-02-18
EP0002570A1 (en) 1979-06-27
FR2409984A1 (fr) 1979-06-22
CH639070A5 (fr) 1983-10-31
IT1101439B (it) 1985-09-28

Similar Documents

Publication Publication Date Title
BE872152A (fr) 4-(di-n-propyl)amino-1,3,4,5-tetrahydrobenzo (cd) indole et son utilisation therapeutique
LU81439A1 (fr) Octahydro-pyrazolo(3,4-g)quinoleines et leur utilisation therapeutique
DK66390D0 (da) Fugtaktiveret, transdermal afgiftsindretning
NL7803036A (nl) 4-(5-fluormethyl-2-pyridyloxy)fenoxyalkaan- carbonzuren en derivaten daarvan.
NO149965C (no) Klebemiddel for medisinske formaal, samt anvendelse derav
BE879586A (fr) Phosphinylalcanoyl prolines, leur preparation et leur utilisation
BE873883A (fr) 6-n-propyl-8-methoxymethyl ou methylmercaptomethylergolines et composes apparentes, et leur utilisation therapeutique
LU80619A1 (fr) Derives heterosidiques de pleuromutiline et leur utilisation therapeutique
LU80922A1 (fr) 9-amino-et imino-dibenzopyrannes et leur utilisation therapeutique
BE869509A (fr) Pyrazoles substitues en position 4, leur preparation et leur utilisation therapeutique
BE871702A (fr) Isochromanes, isothiochromanes, 2-benzoxepines et 2-benzothiepines
BE871807A (fr) 4-quinolyl-guanidines, leur preparation et leur utilisation
BE872134A (fr) Nouvelles indolo (2,3,a) quinolizidines, leur preparation et leur utilisation therapeutique
NL177809C (nl) Verzamel- en uitstalinrichting.
BE872990A (fr) Trans-4a-aryl-octahydro-1h-2-pyrindines et leur utilisation therapeutique
BE868953A (fr) Peptides, leur preparation et leur utilisation
BE866728A (fr) 1,2,4-triazoles, leur preparation et leur utilisation
BE877328A (fr) Octahydro-2h-pyrrolo (3,4-g) quinoleines et leur utilisation therapeutique
BE874430A (fr) 2,3-dihydroimidazo (1,2,c) pyrimidines substituees et leur utilisation therapeutique
SE415383B (sv) Borrkrona, speciellt en stiftborrkrona
AT357357B (de) Faell- und aufarbeitungsvorrichtung
BE877263A (fr) 2-azaergolines et 2-aza-8 (ou 9) ergolenes et leur utilisation therapeutique
BE871724A (fr) 4-desacetoxy-4 alpha-hydroxyindole-dihydroindoles et leur utilisation therapeutique
LU80161A1 (fr) 2,1-benzisothiazoles,leur preparation et leur utilisation therapeutique
LU81350A1 (fr) Arylalkyl-et aryloxyalkyl-phosphonates,leur preparation et leur utilisation therapeutique