BE872152A - 4-(di-n-propyl)amino-1,3,4,5-tetrahydrobenzo (cd) indole et son utilisation therapeutique - Google Patents
4-(di-n-propyl)amino-1,3,4,5-tetrahydrobenzo (cd) indole et son utilisation therapeutiqueInfo
- Publication number
- BE872152A BE872152A BE1009154A BE1009154A BE872152A BE 872152 A BE872152 A BE 872152A BE 1009154 A BE1009154 A BE 1009154A BE 1009154 A BE1009154 A BE 1009154A BE 872152 A BE872152 A BE 872152A
- Authority
- BE
- Belgium
- Prior art keywords
- tetrahydrobenzo
- indole
- propyl
- amino
- therapeutic use
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/854,878 US4110339A (en) | 1977-11-25 | 1977-11-25 | 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole |
Publications (1)
Publication Number | Publication Date |
---|---|
BE872152A true BE872152A (fr) | 1979-05-21 |
Family
ID=25319760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE1009154A BE872152A (fr) | 1977-11-25 | 1978-11-21 | 4-(di-n-propyl)amino-1,3,4,5-tetrahydrobenzo (cd) indole et son utilisation therapeutique |
Country Status (16)
Country | Link |
---|---|
US (1) | US4110339A (es) |
EP (1) | EP0002570B1 (es) |
JP (1) | JPS5481263A (es) |
AR (1) | AR219565A1 (es) |
BE (1) | BE872152A (es) |
CA (1) | CA1108155A (es) |
CH (1) | CH639070A5 (es) |
DE (1) | DE2861487D1 (es) |
DK (1) | DK524778A (es) |
FR (1) | FR2409984A1 (es) |
GB (1) | GB2008587B (es) |
HU (1) | HU176955B (es) |
IE (1) | IE47591B1 (es) |
IL (1) | IL56016A (es) |
IT (1) | IT1101439B (es) |
LU (1) | LU80566A1 (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4282240A (en) * | 1979-11-23 | 1981-08-04 | Merck & Co., Inc. | Amino substituted tetrahydrobenzindoles |
US4501900A (en) * | 1979-11-23 | 1985-02-26 | Merck & Co., Inc. | Amino substituted tetrahydrobenzindoles |
FR2471373A1 (fr) * | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouveaux derives de la benzindolamine, leurs sels, procede de preparation, application a titre de medicaments et composition les renfermant |
EP0034989B1 (fr) * | 1980-02-26 | 1983-10-05 | Roussel-Uclaf | Nouveaux dérivés du cycloheptindolol et leurs sels avec les acides, leur préparation, leur application comme médicaments et les compositions les renfermant |
FR2493842A1 (fr) * | 1980-11-07 | 1982-05-14 | Roussel Uclaf | Nouveaux derives de l'aminocycloheptindole, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant |
US4454150A (en) * | 1981-10-19 | 1984-06-12 | Ayerst, Mckenna & Harrison Inc. | 6,7,8,9-Tetrahydro-3H-benz(e)indol-7-amines and a method of dopamine receptor stimulation therewith |
CA1159459A (en) * | 1980-12-11 | 1983-12-27 | Andre A. Asselin | 6,7,8,9-tetrahydro-3h-benz¬e| indolamine derivatives |
US4510157A (en) * | 1982-12-27 | 1985-04-09 | Ayerst, Mckenna & Harrison, Inc. | 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives |
US4470990A (en) * | 1983-03-14 | 1984-09-11 | Ayerst, Mckenna & Harrison Inc. | 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants |
DE3346573A1 (de) * | 1983-12-23 | 1985-07-04 | Troponwerke GmbH & Co KG, 5000 Köln | 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung |
US4576959A (en) * | 1984-02-06 | 1986-03-18 | Eli Lilly And Company | 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles |
US4983622A (en) * | 1984-02-06 | 1991-01-08 | Eli Lilly And Company | 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles |
US5026869A (en) * | 1984-02-06 | 1991-06-25 | Eli Lilly And Company | 6-substituted-4-dialkylaminotetrahydrobenz(c,d)indoles |
CA1266482A1 (en) * | 1984-05-24 | 1990-03-06 | Carl Kaiser | 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines |
DE3809155A1 (de) * | 1988-03-18 | 1989-09-28 | Bayer Ag | 1,3,4,5-tetrahydrobenz-(c,d)-indole |
US5204340A (en) * | 1989-04-11 | 1993-04-20 | Eli Lilly And Company | Tetrahydrobenz(c,d)indole serotonin agonists |
US5273975A (en) * | 1989-06-09 | 1993-12-28 | The Upjohn Company | Heterocyclic amines having central nervous system activity |
IL97309A (en) * | 1990-02-26 | 1996-11-14 | Lilly Co Eli | Intermediates for hexahydrobenz] [DC indoles and a process for making their pure enantiomers |
TW219933B (es) * | 1990-02-26 | 1994-02-01 | Lilly Co Eli | |
US5302612A (en) * | 1990-02-26 | 1994-04-12 | Eli Lilly And Company | 6-substituted-hexahydrobenz[cd]indoles |
US5212319A (en) * | 1990-02-26 | 1993-05-18 | Eli Lilly And Company | Intermediates to 4-amino-hexahydrobenz[cd]indoles and processes therefor |
US5229410A (en) * | 1990-08-15 | 1993-07-20 | Eli Lilly And Company | 6-substituted-hexahydrobenz[cd]indoles |
US5229409A (en) * | 1990-08-15 | 1993-07-20 | Eli Lilly And Company | 6-substituted-tetrahydrobenz[cd]indoles |
US5364856A (en) * | 1991-03-28 | 1994-11-15 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles |
US5665744A (en) * | 1991-03-28 | 1997-09-09 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenzn [cd] indoles |
US5347013A (en) * | 1991-03-28 | 1994-09-13 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles |
US5244911A (en) * | 1991-03-28 | 1993-09-14 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof |
US5244912A (en) * | 1991-03-28 | 1993-09-14 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof |
EP0690843B1 (en) * | 1993-03-25 | 2000-08-30 | PHARMACIA & UPJOHN COMPANY | Formyl- or cyano- substituted indole derivatives having dopaminergic activity |
CZ285762B6 (cs) * | 1993-06-10 | 1999-11-17 | Eli Lilly And Company | Farmaceutický prostředek vhodný pro prevenci dávení a zvracení a pro ošetřování sexuální dysfunkce savců a jeho použití |
ATE159943T1 (de) | 1993-07-27 | 1997-11-15 | Upjohn Co | Heterozyclische amine mit zns-wirksamkeit |
US7074927B2 (en) * | 1999-05-13 | 2006-07-11 | Pharmacia & Upjohn Company | Heterocyclic amines having central nervous system activity |
JP6518355B2 (ja) * | 2018-02-06 | 2019-05-22 | 株式会社ネオス | フッ素系重合体及びこれを含有する表面処理剤 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3200130A (en) * | 1963-08-27 | 1965-08-10 | Upjohn Co | Derivatives of 1, 3, 4, 5-tetrahydro-benz[cd]indoles |
-
1977
- 1977-11-25 US US05/854,878 patent/US4110339A/en not_active Expired - Lifetime
-
1978
- 1978-10-30 CA CA314,920A patent/CA1108155A/en not_active Expired
- 1978-11-20 JP JP14404378A patent/JPS5481263A/ja active Granted
- 1978-11-20 GB GB7845211A patent/GB2008587B/en not_active Expired
- 1978-11-20 DE DE7878300644T patent/DE2861487D1/de not_active Expired
- 1978-11-20 EP EP78300644A patent/EP0002570B1/en not_active Expired
- 1978-11-21 AR AR274509A patent/AR219565A1/es active
- 1978-11-21 BE BE1009154A patent/BE872152A/xx not_active IP Right Cessation
- 1978-11-21 IL IL56016A patent/IL56016A/xx unknown
- 1978-11-21 FR FR7832806A patent/FR2409984A1/fr active Granted
- 1978-11-23 LU LU80566A patent/LU80566A1/xx unknown
- 1978-11-24 IT IT30205/78A patent/IT1101439B/it active
- 1978-11-24 HU HU78EI820A patent/HU176955B/hu unknown
- 1978-11-24 DK DK524778A patent/DK524778A/da not_active Application Discontinuation
- 1978-11-24 IE IE2325/78A patent/IE47591B1/en unknown
- 1978-11-24 CH CH1207978A patent/CH639070A5/fr not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
LU80566A1 (fr) | 1979-03-22 |
DE2861487D1 (en) | 1982-02-18 |
GB2008587B (en) | 1982-02-17 |
HU176955B (hu) | 1981-06-28 |
IT7830205A0 (it) | 1978-11-24 |
US4110339A (en) | 1978-08-29 |
EP0002570A1 (en) | 1979-06-27 |
IT1101439B (it) | 1985-09-28 |
GB2008587A (en) | 1979-06-06 |
JPS5481263A (en) | 1979-06-28 |
IL56016A0 (en) | 1979-01-31 |
IE47591B1 (en) | 1984-05-02 |
IL56016A (en) | 1981-11-30 |
DK524778A (da) | 1979-05-26 |
FR2409984A1 (fr) | 1979-06-22 |
JPS6160830B2 (es) | 1986-12-23 |
CH639070A5 (fr) | 1983-10-31 |
FR2409984B1 (es) | 1981-11-27 |
IE782325L (en) | 1979-05-25 |
EP0002570B1 (en) | 1981-12-30 |
CA1108155A (en) | 1981-09-01 |
AR219565A1 (es) | 1980-08-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: ELI LILLY AND CY Effective date: 19891130 |