LU504550B1 - A TRADITIONAL CHINESE MEDICINE COMPOSITION AND ITS PRODUCTION METHOD AND APPLICATION - Google Patents

Abstract

The present invention provides a traditional Chinese medicine composition and its production and use. By assembling white-flowered snake tongue grass, chonglou, fly agaric, musk, sage, sanghuang, codonopsis, half side lotus, black ants, half lotus branch, niuhuang, millipede, seaweed, wuweizi, reishi, the cost of cancer treatment is reduced and the economic burden of the patient is reduced ; by killing cancer cells, softening and dispersing nodules and strengthening immunity, the efficiency of treatment is greatly improved and symptoms are quickly relieved; it treats a wide range of cancers and is effective in both high and low cancer differentiation.

Description

A traditional Chinese medicine composition and its preparation method-V504550 and application

Technical part

The present invention relates to the field of pharmaceutical technology, and more particularly to a Chinese medicine composition and a method and application for producing the same.

Technology in the background

Cancer patients often suffer from Qi and blood deficiency and blood congestion, which are often caused by the

Penetration of evil and toxins are caused, resulting in the accumulation of mucus and

Dampness and leads to the internal accumulation of heat and toxins, leading to a deficiency of Qi and blood and the development of cancer. The conventional treatment methods are surgery, chemotherapy, radiation therapy and other treatment methods, due to the late detection and diagnosis of cancer, some have lost the ability to operate, and chemotherapy and radiation therapy toxic side effects are more common and one

Variety of complications causing a lot of pain for the patients. The patent

CN200310103214.3 discloses a preparation of ginseng and astragalus fuzheng from Chinese anticancer medicine, which has the function of activating blood circulation and

Eliminate blood congestion, tonify the Qi and nourish the blood, the body's own

To strengthen resistance to cancer, the treatment method of clearing heat and

To use detoxification, activate blood circulation and eliminate blood congestion, mucus and

dissolving moisture, etc., to drive away evil without harming righteousness, and the comprehensive function of supporting righteousness, eliminating

to emphasize blood stasis and the expulsion of evil. However, the efficiency is low and the

Effect is poor, both in terms of the theoretical considerations of Chinese medicine and the herbal formulations that need to be improved.

Content of the invention

In response to the shortcomings of the prior art, the present invention provides one

Composition of traditional Chinese medicine prepared to address the problem of minor

Efficiency and the poor effect of treatment with traditional Chinese medicine

State of the art solves.

One of the objects of the present invention is to provide a composition for traditional Chinese medicine, and in order to achieve the above objects, the following is used

Solution used: The composition for traditional Chinese medicine includes a medicinal liquid A and a medicinal powder B. The medicinal liquid A includes the following components in parts by mass: 12-14 parts white-flowered

Worm's tongue grass, 12-14 parts half lotus branch, 12-14 parts half side lotus, 8-12 parts

Sanghuang, 8-12 parts seaweed, 8-12 parts sage, 4-6 parts centipede, 9-12 parts chonglou, 3-5 parts codonopsis, 4-6 parts wuweizi, 4-6 parts reishi; medicinal powder B includes the following bulk components: 4-6 parts of black ants, 1.51-2 parts of musk, 3-6 parts

Fly agaric, 1.5-3 parts Niuhuang, 12-30 parts Chonglou.

Furthermore, the herbal composition includes the medicinal liquid A and the medicinal powder B. The medicinal liquid A comprises the following mass components: 12 parts of white-flowered wrasse, 12 parts of half branch lotus, 12 parts of half side lotus, 8

Parts sanghuang, 8 parts seaweed, 8 parts sage, 6 parts millipede, 9 parts chonglou, 3 parts

Codonopsis, 4 parts Wuweizi, 5 parts Reishi; the medicinal powder B contains the following

Mass components: 4 parts black ants, 1 part musk, 3 parts fly agaric, 1.5 Teit4/504550

Niuhuang and 12 parts Chonglou.

Specifically, the herbal composition of the present invention has a relatively large

Improvement in the theory of Chinese medicine as well as in the idea of formula combination.

The formula of the present invention is based on the herbal medicine of white-flowered snake tongue, chonglou, fly agaric, musk, clearing heat and detoxification and anti-cancer cells as the monarchy; Salvia, sanghuang, codonopsis, half side lotus and

Reishi, increasing immunity as a topic of medicine; black ant, half lotus branch and

Niuhuang, which derive the inner fire as an adjuvant; Centipedes, seaweed and Wuweizi, which soften the vertical and dissolve knots and tonify the kidney Qi.

Specifically, white-flowered snake tongue grass: sweet, light, slightly cold, enters the stomach,

Lung, colon and bladder meridians, with the effect of purifying heat and detoxifying the

Toxins, dispersion carbuncles and nodules, diuretic and eliminating moisture.

Half side lotus: Sweet, light, cold, penetrates the heart and small intestine meridian, has a heat-relieving and detoxifying effect, diuretic, decongestant, anti-cancer, can reduce boils and

Treat swelling, canker sores and swelling pain, poisonous snake bites, this product is sweet, cold, heat dissolving and detoxifying, treats all symptoms of heat and

Poison.

Half lotus branch: Pungent, bitter and cold in nature, belongs to the lung, liver and

Kidney meridians, it can clear and detoxify heat, dissolve blood congestion and stop bleeding,

Induce diuresis and attenuate swelling, wounds and canker sores caused by

Heat toxins caused should be treated both internally and externally.

Sanghuang: sweet, bitter, spicy, cold, non-toxic, belongs to the liver and kidney meridians, has the effect of activating blood circulation, stopping bleeding and harmonizing the stomach to stop diarrhea. Traditionally, mulberry yellow is used as medicine in the form of

Seeds used, with a slightly bitter taste, which can benefit the five intestines, soften the firmness and detoxify the stomach, and is mostly used to stop diarrhea, and can treat conditions such as soft spleen and spleen deficiency and diarrhea.

Seaweed: It has the effect of softening hardness and water, foreign heat and eliminating phlegm, especially through its action of softening hardness and dissolving nodules, treating scrofula, i.e. swollen lymph nodes, and some thyroid diseases , such as thyroid nodules, thyroid goiter or some Hashimoto's disease, thyroid enlargement, pain, etc. Seaweed has a good healing effect. In addition, seaweed has a diuretic effect on edema caused by various causes.

Salvia miltiorrhiza: It has the effects of invigorating blood congestion, promoting menstruation and relieving pain, purifying the heart and eliminating irritation, cooling the blood and eliminating carbuncles. Clinically, it is mainly caused by menstrual disorders

blood stasis and obstruction, abdominal pain after pregnancy, various pains caused by blood stasis such as chest paralysis,

Dysthymia, heat paralysis, swelling and pain caused by wounds and carbuncles.

Centipede: The sharp, warm and poisonous centipede belongs to the liver meridian and is effective in relieving bloating and cramps, relieving pain and attacking toxins to dissolve knots. This agent can be used clinically

It is used to treat a range of cancers such as brain, liver and stomach cancers/504550

It can also be used to treat convulsions and twitches caused by the internal movement of the liver winds, children's anxiety winds, stroke and the

Hemiplegia etc. can be caused. It is also effective in treating the

Symptoms of migraine headache caused by wind dampness and intractable paralysis.

Chonglou is one of the medicines for eliminating heat and detoxifying

Toxins, is naturally bitter and slightly cold and has a low toxic effect. It mainly contains steroidal saponins, sterols, dermoids, flavonoids and other components. Modern pharmacology has confirmed that it has a hemostatic effect, an anti-tumor effect

Effect, has a protective effect on the brain and kidneys as well as an antioxidant effect.

Radix Codonopsis Pilosulae: Sweet in taste and flat in nature, it is one of the

Spleen and lung meridians and has the effect of tonifying the medium and vital energy, strengthening the spleen, supporting the lungs and promoting the production of body fluid.

Wuweizi: sour and sweet in taste, warm in nature, attributed to the function of the lung and kidney meridians; moisturizes the lungs and nourishes the kidneys

Body fluid and astringent sweat, astringent essence and stops diarrhea, astringent waste Qi on the top and nourishes kidney Yang on the bottom, treats persistent cough and asthma caused by lung deficiency or kidney failure, receiving Qi can be collected to treat cough stop and calm asthma.

Ganoderma lucidum: The polysaccharide of Ganoderma lucidum has immunomodulatory, hypoglycemic, hypolipidemic, antioxidant, anti-aging and anti-tumor effects;

Triterpenoids can purify the blood and protect liver function; different

Preparations of Ganoderma lucidum have sedative, antispasmodic, cardiotonic, antiarrhythmic, hypotensive and antitussive effects; Ganoderma lucidum also has anticoagulant, antiplatelet and antiallergic effects.

Black Ant: It has various functions such as strengthening the spleen and

Toning the kidneys, painful and activating menstruation, promoting Qi,

Activation of blood, antiviral, anti-inflammatory and analgesic effects, etc. It is used for the prevention and treatment of rheumatic frozen shoulder, ankylosing spondylitis,

Hemiplegia, sciatica, etc. used. It protects the liver and prevents hepatitis B, alcoholic liver and fatty liver disease, etc. It relieves coughs and asthma and is used to

Treatment of asthma, cough and wheezing as well as chronic bronchitis, emphysema and

Pulmonary heart disease used.

Musk: warm, spicy, goes to the spleen and liver meridians. Musk can regulate sleep, shortening sleep time in small amounts, but the dosage should be appropriate.

Musk can also increase blood pressure, stimulate the heart, inhibit and destroy cancer cells and has anti-tumor effects.

Fly agaric: sweet, spicy, warm, poisonous, belongs to the foot Yangming and Shao Yin meridians, with detoxification and swelling, strong heart to relieve pain. Fly agaric poison has one

Digitalis-like effect, which in small doses increases the contraction of the heart and in large doses stops the heart in systole. Fly agaric also has anti-inflammatory, anti-tumor and anti-radiation effects.

Niuhuang: bitter, cool, belonging to the liver and heart meridians, with the effect of eliminating and detoxifying Hitk4/504550, calming the wind and stopping terror, and the

To open mucus and open the body opening.

Specifically, Chinese herbal medicines Bupleurum and Chonglou have a bioalkaline substance that can control the division of cancer cells while maintaining a good therapeutic state of mind. The body's theophylline also prevents the production of cancer cells, making the patient feel comfortable and recover faster, allowing for better and faster treatment.

The second aim of the present invention is to provide a method for producing the Chinese

Medicine composition addressing the problem of producing Chinese medicine

Composition resolves, as well as further improving the therapeutic effect of Chinese medicine composition.

To achieve the above, the present invention uses the following

Embodiments:

Adding water to bulk portions of white-flowered snake tongue, half

Branch lotus, half side lotus, sanghuang, seaweed, sage, centipede, chonglou,

Codonopsis, Wuweizi and Ganoderma lucidum, then soaking, cooking with martial

Fire, then boil with moderate heat to get the medicinal liquid

To obtain herbal composition A; Drying the mass parts of black ant,

musk, fly agaric, niuhuang and chonglou and pressing them into powder form and mixing with musk powder to obtain herbal powder B.

In particular, the medicinal solution of the obtained herbal composition

A twice daily, morning and evening, taken orally, and the received medicinal

Powder B is taken orally twice daily, morning and evening.

The third aim of the present invention is to provide an application and combined

To provide application of the herbal compositions mentioned.

In order to achieve the above objectives, the following embodiments are used in the present invention:

The use of the herbal composition mentioned in the production of a

Anti-cancer drug.

Furthermore, the anti-cancer drug includes rectal cancer, stomach cancer, kidney cancer,

Cervical cancer, bladder cancer, fallopian tube cancer, esophageal cancer, skin cancer and

Uterine cancer drugs.

Further, the herbal composition may be in any pharmaceutically acceptable form

Dosage form available; the anticancer drug further comprises a pharmaceutically acceptable carrier and/or an additive.

Furthermore, the dosage form is aqueous and powdery.

In particular, the herbal compositions can act synergistically with commonly used chemotherapeutic and radiotherapeutic drugs when applied to increase effectiveness.

The technical principle of the present invention is that the herbal

Composition based on the following principles: white-flowered snake-tongue grass,

Chonglou, fly agaric, musk, clearing heat and detoxifying and anti-cancer cells as the

Monarch; Sage, sanghuang, codonopsis, half side lotus and reishi, increasing immunity as the minister; black ant, half lotus branch and Niuhuang, draining internal fire as the adjuvant; Millipede, seaweed and Wuweizi, softly erect and disperse Knotd/204550 and tonify the effect of kidney Qi.

Compared with the prior art, the present invention has the following advantageous effects: 5 By using the Chinese herbal composition formulation of the present invention, the cost of cancer treatment is reduced and the Jijing

patient stress relieved; by killing cancer cells, softening vertical and dispersing nodes and strengthening immunity, the efficiency of the

Treatment significantly improved and symptoms are quickly relieved; the type of cancer treated is broad and both high and low cancer differentiation are effective.

Detailed description

The technical embodiments of the present invention are described below

Connection described in more detail with exemplary embodiments.

Embodiment 1 Preparation of an anticancer agent

Recipe 1: 12g white-flowered snake tongue grass, 12g half lotus branch, 12g half

Side lotus, 8g sanghuang, 8g seaweed, 8g sage, 4 parts centipede, 9g chonglou, 3g radix

Codonopsis, 4g Wuweizi, 4g Ganoderma lucidum; 4g Black Ant, 1g Musk, 3g

Fly agaric, 1.5g Niuhuang, 12g C. Chonglou.

Recipe 2: 13g white-flowered snake tongue grass, 13g C. half lotus branch, 13g half

Side lotus, 10g sanghuang, 10g seaweed, 10g sage, 5 parts millipede, 10g chonglou, 4g

Codonopsis, 5g Wuweizi, 5g Reishi; 5g black ant, 1g musk, 4g fly agaric, 2g

Niuhuang, 20g Chonglou.

Recipe 3: 14g white-flowered snake tongue grass, 14g half lotus branch, 14g half

Side lotus, 12g sanghuang, 12g seaweed, 12g sage, 6 millipedes, 12g chonglou, 5 parts

Codonopsis, 6 parts Wuweizi, 6 parts Reishi; 6 parts Black Ant, 2 parts Musk, 6 parts

Fly agaric, 2 parts Niuhuang, 30 parts Chonglou.

The Chinese herbal mixtures of formulas 1-3, consisting of white-flowered

Worm's tongue grass, half lotus branch, half side lotus, sanghuang, seaweed, sage,

Centipede, Chonglou, Radix Codonopsis, Wuweizi, Ganoderma lucidum, comes with 1000 ml

Water and then soaked for 30 minutes, boiled on high heat and then boiled on low heat for 30 minutes to obtain the medicinal solution of Chinese herbal mixture A. The said mass parts of black ants, musk, niuhuang and chonglou were dried in the microwave, then ground into powder with a grinder, and then mixed with musk powder to obtain Chinese herbal powder B.

Embodiment 2 Animal experiment

Mouse sarcoma, mouse cervical cancer and mouse liver cancer were selected as experimental tumor voices. The test subjects were 18-22g Kunming mice, 5 mice in each group, divided into water, powder, drug and control groups. The mice were inoculated with the tumor source for 10-12 days and their body weights were recorded after inoculation. The

Dose was determined according to the body weight of the mice. After 2 weeks, the mice were weighed and executed, the tumors were removed and weighed, and the middle

Tumor inhibition rate of each group was calculated.

The results were obtained according to the standard of the “In vivo screening protocol for anti-

Tumor drugs” and the results are shown in Table 1: the wiissrige/204550

group and the powder combination drug group both had more obvious

Tumor suppression effect, but the tumor suppression effect of the combined

Administration of the Chinese medicine liquid combination A and the Chinese medicine powder B of the present invention was better while the tumor

Control group became larger due to the continuous development of the tumor.

Table 1

Embodiment 3 Clinical effectiveness

The herbal composition formulation of the present invention has shown remarkable effectiveness in long-term clinical use and received good comments from the majority of patients based on clinical use in recent times

years, as shown in Table 2. In clinical use, using the specific herbal composition A liquid twice daily for oral administration in the morning and evening, and herbal powder B twice daily for oral administration in the morning and evening, there are fewer sample cases in certain cases, but overall may one can see that this herbal composition has excellent effectiveness and clinical

treatment prospects in the treatment of cancer.

Table 2

Maen LR TET TT TTT uae A EE se TS cotisant EEE EEE EEE snnnnnnnnnntansnnesnnnnnnt

Lo aa aa { esophagus stress À = ; 3 ; Ÿ } 8 ; = 3 U È

Case example:

Case 1: Zeng Moumou, male, works as a tailor in Huangjiatang, urinary frequency and

Urgency, diagnosed as kidney cancer after examination with the same drug in

Wuhan, the drug was given for 2 months after the symptoms disappeared, then went to

Work in Guangzhou and everything is good now.

Case 2: Tang Moumou, 52 years old, suffered from uterine cancer and bled more than once

Urination, was diagnosed as uterine cancer in the hospital, the bleeding increased 504550 after three months of taking the drug, and still no relapse.

Case 3: Kidney cancer, male, 50 years old, frequent urination, urge to urinate, frequent

Urination, radiation, chemotherapy in the hospital, patient weak, bad

Diet, dizziness, then treated with prescription, cancer cells stopped metastasis,

Symptoms disappeared after 2 months of using the prescription.

Case 4: Yao Moumou, 60 years old, male, resident of Huangjiatang, was treated for lung cancer for one year and was in good condition. His brother, who also had lung cancer, often rubbed himself with an IV tube, did not move or eat because he was in a bad mood, and did not take the medicine of this formula and died after six months.

Case 5: Nie Moumou, male, Huangjiatang, was diagnosed with lung cancer of the right lung in Tongji in 1998, he coughed and coughed up blood, and after a month

His condition did not improve during his hospital stay. After taking this Chinese medicine formula for three months, his condition improved and has not recurred to date.

Case 6: Liu Moumou, in June 2019, spent 300,000 yuan in Wuhan Tongji Hospital for surgery and chemotherapy for 2 times for rectal cancer, three months later

Cancer cells spread, took this formula for 2 months, and continued to take it for 2 months, after stopping it for a month and a half because of the epidemic, now recovered and back to work for more than a year.

Case 7: Huangjiatang Ms. Peng, 50 years old, had surgery for ovarian cancer

Wuhan Union Medical College Hospital, only 2 years after the cancer metastasized, went to

Wuhan for a check and lived at most 3 months, took this formula drug for 6 months to recover, went to the hospital for a check, everything was normal, and is still alive and well.

In clinical treatment, this herbal combination formula has an effectiveness on the

Differentiation stages of cancer, liquid A and powder B can be used separately,

Liquid A is mainly for clearing heat and detoxification, killing cancer cells,

softening and dispersion; Powder B is for preventing the metastasis of cancer cells, plays a coordinating role, and can also be taken at the same time for a better effect. According to long-term clinical observation, it takes highly differentiated

Cancers 3-4 months to gradually recover; moderately differentiated cancers take 3-4 months to gradually recover; Poorly differentiated cancers generally take more than 1 year to gradually recover.

Embodiment 4 Preparation of a Chinese anticancer drug preparation

The compositions of formulas 1-3 of traditional Chinese medicine

Example 1 was taken, mixed with conventional auxiliaries and with conventional

Methods processed into tablets, capsules, granules, pills, drops and syrups.

Finally, it should be noted that the above embodiments are only for

Illustrate the technical solution of the present invention and are not intended to limit it. Although the invention is described in detail with reference to the preferred

Embodiments are described, it should be understood by those skilled in the art that

Modifications or equivalent substitutions to the technical solution herein

Invention can be made without departing from the purpose and scope of the technical solution of the present invention, which is determined by the scope of the claims of the present

Invention should be covered.

The scope of the claims is covered by the present invention/204550.

Claims (8)

Claims LU504550 1. A traditional Chinese medicine composition, characterized in that the traditional Chinese medicine composition comprises a medicinal liquid A and a medicinal powder B. The medicinal liquid A includes the following components in parts by mass: 12-14 parts of white-flowered snake-tongue grass, 12-14 parts of half lotus branch, 12-14 parts of half side lotus, 8-12 parts of sanghuang, 8-12 parts of seaweed, 8-12 parts of sage, 4-6 parts centipede, 9-12 parts chonglou, 3-5 parts codonopsis, 4-6 parts wuweizi, 4-6 parts reishi; medicinal powder B includes the following bulk components: 4-6 parts of black ants, 1.51-2 parts of musk, 3-6 parts of fly agaric, 1.5-3 parts of Niuhuang, 12-30 parts of Chonglou. 2. A traditional Chinese medicine composition according to claim 1, characterized in that the traditional Chinese medicine composition comprises a medicinal solution A and a medicinal powder B. The medicinal liquid A includes the following mass components: 12 parts of white-flowered snake tongue, 12 parts of half branch lotus, 12 parts of half side lotus, 8 parts of sanghuang, 8 parts of seaweed, 8 parts of sage, 6 parts of centipede, 9 parts of chonglou, 3 parts of codonopsis, 4 parts Wuweizi, 5 parts Reishi; Medicinal powder B contains the following bulk components: 4 parts of black ants, 1 part of musk, 3 parts of fly agaric, 1.5 parts of Niuhuang and 12 parts of Chonglou. 3. A method for producing the Chinese medicine composition according to claims 1 to 2, characterized in that the liquid of Chinese medicine A is prepared by adding water to a mass proportion of white-flowered snake tongue, half branch lotus, half side lotus, sanghuang, seaweed, sage, Centipede, Chonglou, Codonopsis, Wuweizi and Ganoderma lucidum, followed by soaking, boiling at high heat and boiling at low heat, drying the mass proportions of black ant, toad flakes, Niu Huang and chrysanthemum into a powder. The mentioned masses of black ant, musk, fly agaric, niuhuang and chonglou are dried and pressed into powder form and mixed with musk powder to obtain Chinese medicine powder B. 4. The use of the Chinese herbal composition in the production of an anti-cancer drug according to any one of claims 1 to 2 in the production of an anti-cancer drug. 5. The application of the Chinese herbal composition in producing an anti-cancer drug according to claim 4, characterized in that the anti-cancer drug is a drug for rectal cancer, stomach cancer, kidney cancer, cervical cancer, bladder cancer, fallopian tube cancer, esophageal cancer, skin cancer and uterine cancer includes. 6. The use of the Chinese herbal composition in the manufacture of an anti-cancer drug according to claim 4, characterized in that the Chinese herbal composition may be in any pharmaceutically acceptable dosage form; wherein the anticancer drug further comprises a pharmaceutically acceptable carrier and/or an adjuvant. 7. The application of the Chinese herbal composition in the production of an anti-cancer drug according to claim 6, characterized in that the dosage forms are aqueous and powdery. 8. A combination drug for the treatment of cancer, characterized in that the combination drug comprises the herbal composition and the radiotherapy odk}/504550 chemotherapy drug according to one of claims 1 to 2.