LT3893B - Pharmaceutical composition with nalmefene for treating alcoholism - Google Patents
Pharmaceutical composition with nalmefene for treating alcoholism Download PDFInfo
- Publication number
- LT3893B LT3893B LTIP1486A LTIP1486A LT3893B LT 3893 B LT3893 B LT 3893B LT IP1486 A LTIP1486 A LT IP1486A LT IP1486 A LTIP1486 A LT IP1486A LT 3893 B LT3893 B LT 3893B
- Authority
- LT
- Lithuania
- Prior art keywords
- alcohol
- nalmefene
- patient
- treatment
- rats
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Addiction (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/532,424 US5086058A (en) | 1990-06-04 | 1990-06-04 | Method for treating alcoholism with nalmefene |
Publications (2)
Publication Number | Publication Date |
---|---|
LTIP1486A LTIP1486A (en) | 1995-09-25 |
LT3893B true LT3893B (en) | 1996-04-25 |
Family
ID=24121726
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTIP1486A LT3893B (en) | 1990-06-04 | 1993-11-25 | Pharmaceutical composition with nalmefene for treating alcoholism |
Country Status (19)
Country | Link |
---|---|
US (1) | US5086058A (fr) |
EP (1) | EP0531415B1 (fr) |
JP (1) | JP3059213B2 (fr) |
AT (1) | ATE145329T1 (fr) |
AU (1) | AU642748B2 (fr) |
CA (1) | CA2084519C (fr) |
DE (1) | DE69123247T2 (fr) |
DK (1) | DK0531415T3 (fr) |
ES (1) | ES2097209T3 (fr) |
FI (1) | FI925513A (fr) |
GR (1) | GR3022289T3 (fr) |
HU (1) | HU210637B (fr) |
IE (1) | IE77333B1 (fr) |
LT (1) | LT3893B (fr) |
LV (1) | LV10190B (fr) |
NZ (1) | NZ238391A (fr) |
RU (1) | RU2090190C1 (fr) |
WO (1) | WO1991018605A1 (fr) |
ZA (1) | ZA914185B (fr) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4882335A (en) * | 1988-06-13 | 1989-11-21 | Alko Limited | Method for treating alcohol-drinking response |
US6271239B1 (en) * | 1992-04-13 | 2001-08-07 | Regents Of The University Of Minnesota | Delta opioid receptor-selective benzylidene-substituted morphinans |
US5352680A (en) * | 1992-07-15 | 1994-10-04 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists to block opioid agonist tolerance and dependence |
US6096756A (en) * | 1992-09-21 | 2000-08-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
US5580876A (en) * | 1992-09-21 | 1996-12-03 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
USRE36547E (en) * | 1992-09-21 | 2000-02-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by exogenous and endogenous opioid agonists |
US5298622A (en) * | 1993-05-12 | 1994-03-29 | Regents Of The University Of Minnesota | Spiroindane opiate analogs |
US5457208A (en) | 1993-06-21 | 1995-10-10 | Regents Of The University Of Minnesota | Kappa opioid receptor antagonists |
US5587381A (en) * | 1995-03-27 | 1996-12-24 | Sinclair; John D. | Method for terminating methadone maintenance through extinction of the opiate-taking responses |
WO1997018781A1 (fr) * | 1995-11-20 | 1997-05-29 | University Of Miami | Procede pour traiter la dependance a la nicotine |
US5878750A (en) * | 1996-11-14 | 1999-03-09 | Clemens; Anton H. | Method of treating the syndrome of coronary heart disease risk factors in humans |
US5780479A (en) * | 1997-04-04 | 1998-07-14 | Regents Of The University Of Minnesota | Use of opioid antagonists to treat impulse-control disorders |
JP2001526229A (ja) | 1997-12-22 | 2001-12-18 | ユーロ−セルティーク,エス.エイ. | オピオイド投薬剤形の乱用を防止する方法 |
US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
HU1500214D0 (hu) | 1997-12-22 | 2002-03-28 | Euro Celtique Sa | Opioid agonista és antagonista hatóanyagot tartalmazó gyógyszerkészítmény |
EP1248800A2 (fr) * | 1999-11-30 | 2002-10-16 | Corixa Corporation | Compositions et methodes destinees au traitement et au diagnostic du cancer du sein |
OA12215A (en) | 2000-02-08 | 2006-05-09 | Euro Celtique Sa | Tamper-resistant oral opioid agonist formulations. |
US6716449B2 (en) | 2000-02-08 | 2004-04-06 | Euro-Celtique S.A. | Controlled-release compositions containing opioid agonist and antagonist |
US20040024004A1 (en) * | 2001-05-04 | 2004-02-05 | Sherman Barry M. | Novel compositions and methods for enhancing potency or reducing adverse side effects of opioid agonists |
US6528520B2 (en) * | 2000-08-15 | 2003-03-04 | Cpd, Llc | Method of treating the syndrome of coronary heart disease risk factors in humans |
US6846831B2 (en) | 2000-08-15 | 2005-01-25 | Cpd, Llc | Method of treating the syndrome of lipodystrophy |
US6262062B1 (en) * | 2000-08-15 | 2001-07-17 | Cpd, Llc | Method of treating the syndrome of coronary heart disease risk factors in humans |
ES2361148T3 (es) | 2001-05-11 | 2011-06-14 | Endo Pharmaceuticals Inc. | Forma de dosificación de opioides de liberación controlada resistente al abuso. |
ATE540613T1 (de) * | 2001-07-13 | 2012-01-15 | Arkray Inc | Analysevorrichtung und durchstechelement- integrierte verbindung für eine konzentrationsanalysevorrichtung |
DE60230632D1 (de) * | 2001-07-18 | 2009-02-12 | Euro Celtique Sa | Pharmazeutische kombinationen von oxycodon und naloxon |
IS7142A (is) | 2001-08-06 | 2004-02-05 | Euroceltique S.A. | Lyfjasamsetningar, sem innihalda morfíngerandaefni, ásamt losanlegu en hömdu mótlyfi |
US20030044458A1 (en) | 2001-08-06 | 2003-03-06 | Curtis Wright | Oral dosage form comprising a therapeutic agent and an adverse-effect agent |
AU2002324624A1 (en) * | 2001-08-06 | 2003-02-24 | Euro-Celtique S.A. | Sequestered antagonist formulations |
JP2005508888A (ja) * | 2001-08-14 | 2005-04-07 | バイオティ セラピーズ コーポレイション | アルコール依存症またはアルコール中毒を治療する方法 |
EP2425823A1 (fr) | 2002-04-05 | 2012-03-07 | Euro-Celtique S.A. | Préparation pharmaceutique contenant de l'oxycodone et de la naloxone |
US7501433B2 (en) * | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
PT2561860T (pt) * | 2002-05-31 | 2018-05-08 | Titan Pharmaceuticals Inc | Dispositivo polimérico implantável para a libertação prolongada de buprenorfina |
EP1551372B8 (fr) * | 2002-09-20 | 2018-08-01 | Alpharma Pharmaceuticals LLC | Sous-unite de sequestration et compositions et procedes associes |
EP1610791B1 (fr) * | 2003-03-31 | 2011-02-23 | Titan Pharmaceuticals, Inc. | Dispositif polymere implantable pour liberation prolongee d'agoniste de la dopamine |
US20040202717A1 (en) * | 2003-04-08 | 2004-10-14 | Mehta Atul M. | Abuse-resistant oral dosage forms and method of use thereof |
AU2004229551A1 (en) * | 2003-04-14 | 2004-10-28 | Pain Therapeutics, Inc. | Methods for the treatment of pain comprising opioid antagonists |
TWI347201B (en) | 2003-04-21 | 2011-08-21 | Euro Celtique Sa | Pharmaceutical products,uses thereof and methods for preparing the same |
US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
US20060009478A1 (en) * | 2003-10-15 | 2006-01-12 | Nadav Friedmann | Methods for the treatment of back pain |
EP1604666A1 (fr) * | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioides pour le traitement de la bronchopneumopathie chronique obstructive |
EP1702558A1 (fr) * | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Procédé et dispositif pour évaluer la fonction de l'activité intestinale |
EP2526932B1 (fr) | 2006-06-19 | 2017-06-07 | Alpharma Pharmaceuticals LLC | Composition pharmaceutique |
SI2724722T1 (sl) | 2006-10-20 | 2017-07-31 | Neurendo Pharma, Llc | Postopek za obnovitev učinka inkretina |
US20100266645A1 (en) * | 2007-12-17 | 2010-10-21 | Alfred Liang | Pharmaceutical compositions |
US20100151014A1 (en) * | 2008-12-16 | 2010-06-17 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
US8623418B2 (en) * | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
ATE523512T1 (de) * | 2008-04-24 | 2011-09-15 | Janssen Pharmaceutica Nv | Nalmefen-prodrugs |
KR101598138B1 (ko) * | 2008-04-24 | 2016-02-29 | 얀센 파마슈티카 엔.브이. | 날메펜 디에스테르 프로드럭 |
EP2317991B1 (fr) * | 2008-07-07 | 2017-05-03 | Euro-Celtique S.A. | Utilisation d'antagonistes opioïdes pour le traitement d'une rétention urinaire |
MX347106B (es) | 2009-03-10 | 2017-04-12 | Euro-Celtique S A * | Coposiciones farmacéuticas de liberación inmediata que comprenden oxicodona y naloxona. |
US20140005217A1 (en) * | 2012-06-27 | 2014-01-02 | H. Lundbeck A/S | Nalmefene for reduction of alcohol consumption in specific target populations |
WO2014170353A1 (fr) * | 2013-04-17 | 2014-10-23 | H. Lundbeck A/S | Nalméfène pour le traitement de patients atteints de trouble du sommeil |
CN105517551A (zh) | 2013-07-23 | 2016-04-20 | 欧洲凯尔特公司 | 用于在患有疼痛和导致肠生态失调和/或提高肠细菌移位风险之疾病的患者中治疗疼痛的羟考酮与纳洛酮的组合 |
US20170042887A1 (en) * | 2014-04-22 | 2017-02-16 | Otsuka Pharmaceutical. Co., Ltd. | Combination of Brexpiprazole and Nalmefene and Use Thereof for Treating Substance-Related Disorders |
EP3215154B1 (fr) | 2014-11-07 | 2020-01-29 | Regents of the University of Minnesota | Sels et compositions utiles pour le traitement de maladie |
EP3445363A1 (fr) * | 2016-04-22 | 2019-02-27 | Taiwanj Pharmaceuticals Co., Ltd. | Nalméfène, naltrexone ou dérivés de ceux-ci destinés à être utilisés dans le traitement de la stéatohépatite non alcoolique ou de la maladie du foie gras d'origine non alcoolique |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4882335A (en) | 1988-06-13 | 1989-11-21 | Alko Limited | Method for treating alcohol-drinking response |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4857533A (en) * | 1988-12-15 | 1989-08-15 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for autoimmune diseases |
US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
US5096715A (en) * | 1989-11-20 | 1992-03-17 | Alko Ltd. | Method and means for treating alcoholism by extinguishing the alcohol-drinking response using a transdermally administered opiate antagonist |
-
1990
- 1990-06-04 US US07/532,424 patent/US5086058A/en not_active Expired - Lifetime
-
1991
- 1991-05-10 ES ES91910595T patent/ES2097209T3/es not_active Expired - Lifetime
- 1991-05-10 HU HU9203835A patent/HU210637B/hu unknown
- 1991-05-10 JP JP3509984A patent/JP3059213B2/ja not_active Expired - Lifetime
- 1991-05-10 CA CA002084519A patent/CA2084519C/fr not_active Expired - Lifetime
- 1991-05-10 AT AT91910595T patent/ATE145329T1/de not_active IP Right Cessation
- 1991-05-10 EP EP91910595A patent/EP0531415B1/fr not_active Expired - Lifetime
- 1991-05-10 RU RU9192016403A patent/RU2090190C1/ru active
- 1991-05-10 AU AU79740/91A patent/AU642748B2/en not_active Expired
- 1991-05-10 DK DK91910595.7T patent/DK0531415T3/da active
- 1991-05-10 DE DE69123247T patent/DE69123247T2/de not_active Expired - Lifetime
- 1991-05-10 WO PCT/US1991/003241 patent/WO1991018605A1/fr active IP Right Grant
- 1991-06-03 ZA ZA914185A patent/ZA914185B/xx unknown
- 1991-06-04 IE IE188891A patent/IE77333B1/en not_active IP Right Cessation
- 1991-06-04 NZ NZ238391A patent/NZ238391A/en not_active IP Right Cessation
-
1992
- 1992-12-04 FI FI925513A patent/FI925513A/fi unknown
-
1993
- 1993-08-31 LV LVP-93-1052A patent/LV10190B/en unknown
- 1993-11-25 LT LTIP1486A patent/LT3893B/lt not_active IP Right Cessation
-
1997
- 1997-01-16 GR GR960403307T patent/GR3022289T3/el unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4882335A (en) | 1988-06-13 | 1989-11-21 | Alko Limited | Method for treating alcohol-drinking response |
Non-Patent Citations (2)
Title |
---|
DIXON AT AL.: "Clin.Pharmacol., Vol.27, 1987", pages: 233 - 239 |
YEOMANS ET AL.: "Psycopharmacology, vol. 100, 1990", pages: 426 - 432 |
Also Published As
Publication number | Publication date |
---|---|
HU210637B (en) | 1995-06-28 |
LV10190B (en) | 1995-06-20 |
FI925513A0 (fi) | 1992-12-04 |
JPH06506665A (ja) | 1994-07-28 |
FI925513A (fi) | 1992-12-04 |
GR3022289T3 (en) | 1997-04-30 |
NZ238391A (en) | 1997-06-24 |
HU9203835D0 (en) | 1993-03-29 |
IE911888A1 (en) | 1991-12-04 |
CA2084519C (fr) | 1999-02-09 |
EP0531415B1 (fr) | 1996-11-20 |
WO1991018605A1 (fr) | 1991-12-12 |
EP0531415A1 (fr) | 1993-03-17 |
LTIP1486A (en) | 1995-09-25 |
AU642748B2 (en) | 1993-10-28 |
JP3059213B2 (ja) | 2000-07-04 |
ZA914185B (en) | 1992-07-29 |
HUT65523A (en) | 1994-06-28 |
AU7974091A (en) | 1991-12-31 |
ES2097209T3 (es) | 1997-04-01 |
IE77333B1 (en) | 1997-12-03 |
RU2090190C1 (ru) | 1997-09-20 |
CA2084519A1 (fr) | 1991-12-05 |
LV10190A (lv) | 1994-10-20 |
ATE145329T1 (de) | 1996-12-15 |
DE69123247D1 (de) | 1997-01-02 |
DE69123247T2 (de) | 1998-01-15 |
US5086058A (en) | 1992-02-04 |
DK0531415T3 (da) | 1996-12-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC9A | Transfer of patents |
Free format text: CONTRAL CLINICS OY,TAPIOLAN KESKUSTORNI 6KRS, FIN-02100 ESPOO,FI,990910 |
|
MK9A | Expiry of a patent |
Effective date: 20131125 |