LT3481437T - Radiofluorinimo pirmtakai - Google Patents
Radiofluorinimo pirmtakaiInfo
- Publication number
- LT3481437T LT3481437T LTEPPCT/DE2017/100986T LTDE2017100986T LT3481437T LT 3481437 T LT3481437 T LT 3481437T LT DE2017100986 T LTDE2017100986 T LT DE2017100986T LT 3481437 T LT3481437 T LT 3481437T
- Authority
- LT
- Lithuania
- Prior art keywords
- radiofluorination
- precursors
- Prior art date
Links
- 239000002243 precursor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102016122273.9A DE102016122273B4 (de) | 2016-11-18 | 2016-11-18 | Präkursoren für die Radiofluorierung |
| PCT/DE2017/100986 WO2018091043A1 (de) | 2016-11-18 | 2017-11-17 | Präkursoren für die radiofluorierung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3481437T true LT3481437T (lt) | 2022-05-10 |
Family
ID=60627367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/DE2017/100986T LT3481437T (lt) | 2016-11-18 | 2017-11-17 | Radiofluorinimo pirmtakai |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10759760B2 (lt) |
| EP (1) | EP3481437B1 (lt) |
| JP (2) | JP2019535727A (lt) |
| KR (1) | KR102233598B1 (lt) |
| CN (2) | CN109982722B (lt) |
| AU (1) | AU2017359864B2 (lt) |
| BR (1) | BR112019022760A2 (lt) |
| CA (1) | CA3044102C (lt) |
| DE (1) | DE102016122273B4 (lt) |
| DK (1) | DK3481437T3 (lt) |
| ES (1) | ES2911753T3 (lt) |
| HU (1) | HUE058846T2 (lt) |
| IL (1) | IL266683B2 (lt) |
| LT (1) | LT3481437T (lt) |
| WO (1) | WO2018091043A1 (lt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102016122273B4 (de) * | 2016-11-18 | 2018-06-21 | Abx Advanced Biochemical Compounds Gmbh | Präkursoren für die Radiofluorierung |
| WO2018098390A1 (en) * | 2016-11-23 | 2018-05-31 | Cancer Targeted Technology Llc | Albumin-binding psma inhibitors |
| CN111253465A (zh) * | 2020-03-03 | 2020-06-09 | 复旦大学附属肿瘤医院 | 一种psma结合剂及其用途 |
| CN111548305B (zh) * | 2020-05-12 | 2021-08-31 | 北京师范大学 | 一种可用于靶向psma的喹啉类化合物及其制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009035959A2 (en) * | 2007-09-10 | 2009-03-19 | Ge Healthcare Limited | Radiofluorination methods |
| CN107382846B (zh) * | 2008-08-01 | 2021-07-06 | 约翰.霍普金斯大学 | Psma-结合剂及其用途 |
| WO2011006610A1 (en) * | 2009-07-11 | 2011-01-20 | Bayer Schering Pharma Aktiengesellschaft | Non-polar and polar leaving groups |
| WO2015004029A1 (en) | 2013-07-08 | 2015-01-15 | Technische Universität München | 18f-labeling of aromatic and heteroaromatic molecules with unprotected carboxylic acid groups |
| CN103595631B (zh) | 2013-10-31 | 2016-12-07 | 华为技术有限公司 | 一种路径建立的方法和装置 |
| EP2993171A1 (en) * | 2014-09-04 | 2016-03-09 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Method for the production of 18F-labeled PSMA-specific PET-tracers |
| ES2912753T3 (es) * | 2014-08-24 | 2022-05-27 | Max Planck Gesellschaft Zur Foerderung Der Wss | Método para la producción de ésteres activos marcados con 18F y su aplicación ejemplificada por la preparación de un marcador de PET específico de PSMA |
| US10736974B2 (en) * | 2014-10-22 | 2020-08-11 | The Johns Hopkins University | Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy |
| US11078166B2 (en) * | 2015-08-13 | 2021-08-03 | The Johns Hopkins University | Triazole conjugated ureas, thioureas, carbamates, and reversed carbamates for PSMA-targeted imaging agents and uses thereof |
| US20180236109A1 (en) * | 2015-08-20 | 2018-08-23 | Universitat Zu Koln | Pain Tracking by PET-imaging (Pain-TraP) |
| EA037512B1 (ru) | 2015-09-30 | 2021-04-06 | Дойчес Кребсфоршунгсцентрум | Улучшенные ингибиторы простатического специфического мембранного антигена (псма), меченные 18f, и их применение в качестве визуализирующих агентов при раке простаты |
| US20200231614A1 (en) * | 2015-10-22 | 2020-07-23 | The Johns Hopkins University | Psma targeted radiohalogenated ureas for cancer radiotherapy |
| GB201518918D0 (en) * | 2015-10-26 | 2015-12-09 | Norsk Medisinsk Syklotronsenter As And Uni I Oslo | Method |
| US10882871B2 (en) * | 2016-01-10 | 2021-01-05 | British Columbia Cancer Agency Branch | 18/19F-labelled compounds which target the prostate specific membrane antigen |
| EP3481804A4 (en) * | 2016-06-10 | 2019-11-13 | The Johns Hopkins University | IMPROVED SYNTHESIS OF RADIOACTIVELY MARKED PROSTATE-SPECIFIC MEMBRANE-ANTIBODY (PSMA) INHIBITOR [18F] DCFPYL |
| SG10202013129YA (en) * | 2016-06-28 | 2021-01-28 | Univ Cornell | 18f-labeled triazole containing psma inhibitors |
| DE102016122273B4 (de) * | 2016-11-18 | 2018-06-21 | Abx Advanced Biochemical Compounds Gmbh | Präkursoren für die Radiofluorierung |
-
2016
- 2016-11-18 DE DE102016122273.9A patent/DE102016122273B4/de active Active
-
2017
- 2017-11-17 US US16/348,997 patent/US10759760B2/en active Active
- 2017-11-17 CA CA3044102A patent/CA3044102C/en active Active
- 2017-11-17 EP EP17811189.4A patent/EP3481437B1/de active Active
- 2017-11-17 WO PCT/DE2017/100986 patent/WO2018091043A1/de active Search and Examination
- 2017-11-17 AU AU2017359864A patent/AU2017359864B2/en active Active
- 2017-11-17 KR KR1020197014049A patent/KR102233598B1/ko active IP Right Grant
- 2017-11-17 JP JP2019526545A patent/JP2019535727A/ja active Pending
- 2017-11-17 CN CN201780071047.9A patent/CN109982722B/zh active Active
- 2017-11-17 LT LTEPPCT/DE2017/100986T patent/LT3481437T/lt unknown
- 2017-11-17 HU HUE17811189A patent/HUE058846T2/hu unknown
- 2017-11-17 BR BR112019022760-1A patent/BR112019022760A2/pt unknown
- 2017-11-17 IL IL266683A patent/IL266683B2/en unknown
- 2017-11-17 DK DK17811189.4T patent/DK3481437T3/da active
- 2017-11-17 ES ES17811189T patent/ES2911753T3/es active Active
- 2017-11-17 CN CN202211211433.2A patent/CN115650813B/zh active Active
-
2020
- 2020-01-31 US US16/778,155 patent/US11053200B2/en active Active
-
2021
- 2021-08-03 JP JP2021127369A patent/JP7261269B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL266683B2 (en) | 2023-09-01 |
| JP2019535727A (ja) | 2019-12-12 |
| CA3044102A1 (en) | 2018-05-24 |
| IL266683B1 (en) | 2023-05-01 |
| US10759760B2 (en) | 2020-09-01 |
| EP3481437B1 (de) | 2022-01-26 |
| DK3481437T3 (en) | 2022-04-25 |
| IL266683A (en) | 2019-07-31 |
| US20190263756A1 (en) | 2019-08-29 |
| EP3481437A1 (de) | 2019-05-15 |
| CA3044102C (en) | 2021-08-10 |
| ES2911753T3 (es) | 2022-05-20 |
| US20200165204A1 (en) | 2020-05-28 |
| BR112019022760A2 (pt) | 2020-05-12 |
| CN109982722B (zh) | 2024-03-08 |
| DE102016122273B4 (de) | 2018-06-21 |
| DE102016122273A1 (de) | 2018-05-24 |
| CN115650813B (zh) | 2024-07-19 |
| HUE058846T2 (hu) | 2022-09-28 |
| JP7261269B2 (ja) | 2023-04-19 |
| AU2017359864B2 (en) | 2020-10-22 |
| JP2021176909A (ja) | 2021-11-11 |
| CN115650813A (zh) | 2023-01-31 |
| CN109982722A (zh) | 2019-07-05 |
| KR20190070945A (ko) | 2019-06-21 |
| WO2018091043A1 (de) | 2018-05-24 |
| US11053200B2 (en) | 2021-07-06 |
| AU2017359864A1 (en) | 2019-05-16 |
| KR102233598B1 (ko) | 2021-03-30 |
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