LT3449934T - Ii tipo glikogeno kaupimo ligos gydymas - Google Patents

Ii tipo glikogeno kaupimo ligos gydymas

Info

Publication number
LT3449934T
LT3449934T LTEP18194771.4T LT18194771T LT3449934T LT 3449934 T LT3449934 T LT 3449934T LT 18194771 T LT18194771 T LT 18194771T LT 3449934 T LT3449934 T LT 3449934T
Authority
LT
Lithuania
Prior art keywords
storage disease
disease type
treatment
glycogen storage
glycogen
Prior art date
Application number
LTEP18194771.4T
Other languages
English (en)
Inventor
Yuan-Tsong Chen
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22818451&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3449934(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Duke University filed Critical Duke University
Publication of LT3449934T publication Critical patent/LT3449934T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0102—Alpha-glucosidase (3.2.1.20)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
LTEP18194771.4T 2000-07-18 2001-07-10 Ii tipo glikogeno kaupimo ligos gydymas LT3449934T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21923700P 2000-07-18 2000-07-18

Publications (1)

Publication Number Publication Date
LT3449934T true LT3449934T (lt) 2020-08-10

Family

ID=22818451

Family Applications (3)

Application Number Title Priority Date Filing Date
LTEP14167882.1T LT2767291T (lt) 2000-07-18 2001-07-10 Ii tipo glikogenozės gydymas
LTEP18194771.4T LT3449934T (lt) 2000-07-18 2001-07-10 Ii tipo glikogeno kaupimo ligos gydymas
LTEP16178390.7T LT3108895T (lt) 2000-07-18 2001-07-10 Ii tipo glikogeno kaupimo ligos gydymas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP14167882.1T LT2767291T (lt) 2000-07-18 2001-07-10 Ii tipo glikogenozės gydymas

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP16178390.7T LT3108895T (lt) 2000-07-18 2001-07-10 Ii tipo glikogeno kaupimo ligos gydymas

Country Status (18)

Country Link
US (10) US7056712B2 (lt)
EP (4) EP3449934B1 (lt)
JP (10) JP5113312B2 (lt)
AT (1) ATE355075T1 (lt)
AU (3) AU7194101A (lt)
BR (1) BR0113006A (lt)
CA (1) CA2416492C (lt)
CY (2) CY1120977T1 (lt)
DE (1) DE60126947T2 (lt)
DK (5) DK3449934T3 (lt)
ES (5) ES2277931T3 (lt)
HK (3) HK1054690A1 (lt)
LT (3) LT2767291T (lt)
MX (1) MXPA03000474A (lt)
PT (5) PT1301201E (lt)
SI (3) SI3449934T1 (lt)
TW (1) TWI280882B (lt)
WO (1) WO2002005841A1 (lt)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2767291T (lt) * 2000-07-18 2016-11-25 Duke University Ii tipo glikogenozės gydymas
ES2300439T3 (es) * 2001-04-30 2008-06-16 Zystor Therapeutics , Inc. Reconocimiento subcelular de proteinas terapeuticas.
US20040005309A1 (en) * 2002-05-29 2004-01-08 Symbiontics, Inc. Targeted therapeutic proteins
US7629309B2 (en) * 2002-05-29 2009-12-08 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US7560424B2 (en) 2001-04-30 2009-07-14 Zystor Therapeutics, Inc. Targeted therapeutic proteins
US20030072761A1 (en) * 2001-10-16 2003-04-17 Lebowitz Jonathan Methods and compositions for targeting proteins across the blood brain barrier
US20060018882A1 (en) * 2004-06-21 2006-01-26 Kaemmerer William F Medical devices and methods for delivering compositions to cells
PT1587923E (pt) 2003-01-22 2011-12-07 Univ Duke Construções melhoradas para a expressão de polipéptidos lisossomais
US7442372B2 (en) 2003-08-29 2008-10-28 Biomarin Pharmaceutical Inc. Delivery of therapeutic compounds to the brain and other tissues
US7129049B2 (en) * 2003-12-22 2006-10-31 Regents Of The University Of Minnesota Method of detecting equine glycogen storage disease IV
CN1922313B (zh) * 2004-02-10 2011-10-26 生物马林医药公司 酸性α-糖苷酶及其片段
US20050208090A1 (en) * 2004-03-18 2005-09-22 Medtronic, Inc. Methods and systems for treatment of neurological diseases of the central nervous system
WO2008063511A2 (en) * 2006-11-13 2008-05-29 Zystor Therapeutics, Inc. Methods for treating pompe disease
WO2009075815A1 (en) 2007-12-07 2009-06-18 Duke University Immunomodulating gene therapy
US20110223147A1 (en) 2008-05-07 2011-09-15 Zystor Therapeutics, Inc. Lysosomal targeting peptides and uses thereof
US9050333B2 (en) 2008-07-08 2015-06-09 Duke University Method of treating glycogen storage disease type III with human acid α-glucosidase
EP3075386B1 (en) 2009-06-17 2019-10-16 BioMarin Pharmaceutical Inc. Formulations for lysosomal enzymes
US8809282B2 (en) 2010-05-06 2014-08-19 Duke University Method of reducing titers of antibodies specific for a therapeutic agent
CN105189542A (zh) 2013-02-20 2015-12-23 瓦莱里昂治疗有限责任公司 用于治疗庞贝氏症的方法和组合物
SG10201710448SA (en) * 2013-05-15 2018-01-30 Univ Minnesota Adeno-associated virus mediated gene transfer to the central nervous system
EA038986B1 (ru) 2014-09-30 2021-11-18 Амикус Терапьютикс, Инк. Высокоактивная кислая альфа-глюкозидаза с повышенным содержанием углеводов
EP3292871B1 (en) 2015-05-07 2021-06-23 The University of Tokyo Nanoreactor using polyion complex polymersomes, and method for producing same
MA44747A (fr) * 2015-08-31 2019-03-06 Univ Duke Méthodes et compositions pour le traitement de troubles associés à une accumulation du glycogène cytoplasmique
US10940125B2 (en) 2015-09-18 2021-03-09 Duke University Methods and compositions for the treatment of steatosis-associated disorders
BR112018013151A2 (pt) 2015-12-30 2018-12-18 Amicus Therapeutics Inc alfa-glicosidase ácida aumentada para o tratamento da doença de pompe
AU2017239641A1 (en) 2016-03-30 2018-10-18 Amicus Therapeutics, Inc. Formulations comprising recombinant acid alpha-glucosidase
US10227577B2 (en) 2016-03-30 2019-03-12 Amicus Therapeutics, Inc. Method for selection of high M6P recombinant proteins
SG11201808176TA (en) 2016-04-15 2018-10-30 The Trustees Of The Univ Of Pennsyvania Gene therapy for treating mucopolysaccharidosis type ii
KR20200104852A (ko) 2017-09-22 2020-09-04 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 Ii형 점액다당류증의 치료를 위한 유전자 요법
WO2020163480A1 (en) * 2019-02-05 2020-08-13 Amicus Therapeutics, Inc. Recombinant human acid alpha-glucosidase and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3063911A (en) * 1961-04-03 1962-11-13 Taisho Pharmaceutical Co Ltd Acid-stable digestive enzyme preparation and process of making same
US5464778A (en) 1989-03-08 1995-11-07 Board Of Regents Of The University Of Oklahoma Glycoprotein ligand for P-selectin and methods of use thereof
US5356804A (en) * 1990-10-24 1994-10-18 Mount Sinai School Of Medicine Of The City Of New York Cloning and expression of biologically active human α-galactosidase A
US6118045A (en) 1995-08-02 2000-09-12 Pharming B.V. Lysosomal proteins produced in the milk of transgenic animals
CN1300323A (zh) 1998-05-13 2001-06-20 加州大学洛杉矶分校港口研究和教育院 重组α－L－艾杜糖苷酸酶,其生产和纯化的方法以及治疗其缺乏导致的疾病的方法
ES2677343T3 (es) * 1998-12-07 2018-08-01 Genzyme Corporation Tratamiento de la enfermedad de Pompe
US6537785B1 (en) 1999-09-14 2003-03-25 Genzyme Glycobiology Research Institute, Inc. Methods of treating lysosomal storage diseases
LT2767291T (lt) * 2000-07-18 2016-11-25 Duke University Ii tipo glikogenozės gydymas
US7629309B2 (en) 2002-05-29 2009-12-08 Zystor Therapeutics, Inc. Targeted therapeutic proteins
CN1922313B (zh) * 2004-02-10 2011-10-26 生物马林医药公司 酸性α-糖苷酶及其片段
US8470552B2 (en) 2009-10-12 2013-06-25 Keck Graduate Institute Strategy to reduce lactic acid production and control PH in animal cell culture

Also Published As

Publication number Publication date
DK2767291T3 (en) 2016-12-05
JP2004503598A (ja) 2004-02-05
DE60126947D1 (de) 2007-04-12
SI2767291T1 (sl) 2016-11-30
PT3449934T (pt) 2020-06-25
PT1301201E (pt) 2007-03-30
JP2018002749A (ja) 2018-01-11
ES2700865T3 (es) 2019-02-19
SI3108895T1 (sl) 2019-01-31
EP2767291B1 (en) 2016-09-14
US20100254966A1 (en) 2010-10-07
US20210169996A1 (en) 2021-06-10
EP3108895B1 (en) 2018-09-19
AU7194101A (en) 2002-01-30
DE60126947T2 (de) 2007-10-31
US9907839B2 (en) 2018-03-06
JP2017137357A (ja) 2017-08-10
JP2016056206A (ja) 2016-04-21
ATE355075T1 (de) 2006-03-15
JP6163216B2 (ja) 2017-07-12
DK1782825T3 (da) 2014-11-03
CY1123084T1 (el) 2021-10-29
US9370556B2 (en) 2016-06-21
JP2013231081A (ja) 2013-11-14
JP2012006953A (ja) 2012-01-12
LT3108895T (lt) 2018-11-26
US8900552B2 (en) 2014-12-02
ES2277931T3 (es) 2007-08-01
US20050123531A1 (en) 2005-06-09
JP2014185187A (ja) 2014-10-02
US20020110551A1 (en) 2002-08-15
US20130195834A1 (en) 2013-08-01
HK1103363A1 (en) 2007-12-21
WO2002005841A1 (en) 2002-01-24
US20120058132A1 (en) 2012-03-08
PT1782825E (pt) 2014-11-04
US20150004152A1 (en) 2015-01-01
CA2416492C (en) 2008-04-29
US20080175833A1 (en) 2008-07-24
SI3449934T1 (sl) 2020-09-30
AU2001271941B2 (en) 2007-03-01
DK1301201T3 (da) 2007-04-02
JP2020019822A (ja) 2020-02-06
PT3108895T (pt) 2018-12-18
DK3449934T3 (da) 2020-06-29
TWI280882B (en) 2007-05-11
EP3108895A1 (en) 2016-12-28
ES2523024T3 (es) 2014-11-20
EP2767291A2 (en) 2014-08-20
EP3449934A1 (en) 2019-03-06
JP5113312B2 (ja) 2013-01-09
MXPA03000474A (es) 2003-10-06
PT2767291T (pt) 2016-10-25
LT2767291T (lt) 2016-11-25
JP2018199721A (ja) 2018-12-20
US20180185457A1 (en) 2018-07-05
AU2010200487A1 (en) 2010-03-04
EP3449934B1 (en) 2020-05-20
HK1197656A1 (zh) 2015-02-06
HK1054690A1 (en) 2003-12-12
ES2799882T3 (es) 2020-12-22
ES2599401T3 (es) 2017-02-01
JP5792774B2 (ja) 2015-10-14
EP1301201A1 (en) 2003-04-16
EP1301201B1 (en) 2007-02-28
CA2416492A1 (en) 2002-01-24
DK3108895T3 (en) 2018-11-26
EP2767291A3 (en) 2014-10-08
US10792341B2 (en) 2020-10-06
CY1120977T1 (el) 2019-12-11
US20160184410A1 (en) 2016-06-30
JP2008081507A (ja) 2008-04-10
BR0113006A (pt) 2004-10-19
US7056712B2 (en) 2006-06-06

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