LT3096737T - Stabili glikopironio bromido ir formoterolio derinio suspausto aerozolio tirpalo kompozicija - Google Patents

Stabili glikopironio bromido ir formoterolio derinio suspausto aerozolio tirpalo kompozicija

Info

Publication number
LT3096737T
LT3096737T LTEP14827449.1T LT14827449T LT3096737T LT 3096737 T LT3096737 T LT 3096737T LT 14827449 T LT14827449 T LT 14827449T LT 3096737 T LT3096737 T LT 3096737T
Authority
LT
Lithuania
Prior art keywords
solution composition
glycopyrronium bromide
aerosol solution
pressurised aerosol
formoterol combination
Prior art date
Application number
LTEP14827449.1T
Other languages
English (en)
Inventor
Sauro Bonelli
Diego Copelli
Massimiliano Dagli Alberi
Francesca Usberti
Enrico Zambelli
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49886776&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3096737(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of LT3096737T publication Critical patent/LT3096737T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/124Aerosols; Foams characterised by the propellant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007Mechanical counters
    • A61M15/0071Mechanical counters having a display or indicator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/44Valves specially adapted therefor; Regulating devices
    • B65D83/52Valves specially adapted therefor; Regulating devices for metering
    • B65D83/54Metering valves ; Metering valve assemblies
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/75Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • B65D83/752Aerosol containers not provided for in groups B65D83/16 - B65D83/74 characterised by the use of specific products or propellants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22Valves or arrangement of valves
    • A61M2039/226Spindles or actuating means

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Mechanical Engineering (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
LTEP14827449.1T 2013-12-30 2014-12-23 Stabili glikopironio bromido ir formoterolio derinio suspausto aerozolio tirpalo kompozicija LT3096737T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13199783 2013-12-30
PCT/EP2014/079258 WO2015101575A1 (en) 2013-12-30 2014-12-23 Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination

Publications (1)

Publication Number Publication Date
LT3096737T true LT3096737T (lt) 2018-06-11

Family

ID=49886776

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP14827449.1T LT3096737T (lt) 2013-12-30 2014-12-23 Stabili glikopironio bromido ir formoterolio derinio suspausto aerozolio tirpalo kompozicija

Country Status (36)

Country Link
US (3) US20150182459A1 (lt)
EP (1) EP3096737B1 (lt)
JP (2) JP6534397B2 (lt)
KR (1) KR101865131B1 (lt)
CN (2) CN105848642A (lt)
AR (1) AR098983A1 (lt)
AU (1) AU2014375300B2 (lt)
BR (1) BR112016014586A2 (lt)
CA (1) CA2935302C (lt)
CL (1) CL2016001652A1 (lt)
CY (1) CY1120205T1 (lt)
DK (1) DK3096737T3 (lt)
EA (1) EA033228B1 (lt)
ES (1) ES2666905T4 (lt)
GE (1) GEP20186870B (lt)
HR (1) HRP20180944T1 (lt)
HU (1) HUE039359T2 (lt)
IL (1) IL246502B (lt)
LT (1) LT3096737T (lt)
MA (1) MA39154A1 (lt)
ME (1) ME03076B (lt)
MX (1) MX368834B (lt)
MY (1) MY176191A (lt)
NO (1) NO3096737T3 (lt)
PE (1) PE20161132A1 (lt)
PH (1) PH12016501269A1 (lt)
PL (1) PL3096737T3 (lt)
PT (1) PT3096737T (lt)
RS (1) RS57269B1 (lt)
SA (1) SA516371428B1 (lt)
SG (1) SG11201605309UA (lt)
SI (1) SI3096737T1 (lt)
TN (1) TN2016000262A1 (lt)
TR (1) TR201809356T4 (lt)
UA (1) UA117846C2 (lt)
WO (1) WO2015101575A1 (lt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2515853B1 (en) * 2009-12-23 2014-03-19 Chiesi Farmaceutici S.p.A. Combination therapy for COPD
SG181870A1 (en) 2009-12-23 2012-07-30 Chiesi Farma Spa Aerosol formulation for copd
NZ600790A (en) 2009-12-23 2014-09-26 Chiesi Farma Spa Combination therapy for copd
PL3089735T3 (pl) * 2013-12-30 2018-12-31 Chiesi Farmaceutici S.P.A. Trwała ciśnieniowa kompozycja roztworu aerozolowego kombinacji bromku glikopironium i formoterolu
TR201809356T4 (tr) * 2013-12-30 2018-07-23 Chiesi Farm Spa Gli̇kopi̇ronyum bromür ve formoterol kombi̇nasyonunun stabi̇l basinçli aerosol çözelti̇ kompozi̇syonu.
GB201520862D0 (en) * 2015-11-25 2016-01-13 Jagotec Ag Pharmaceutical composition
TW201735914A (zh) * 2015-12-22 2017-10-16 阿斯特捷利康公司 用於治療慢性阻塞性肺疾病之醫藥組成物
US10098837B2 (en) * 2016-07-28 2018-10-16 Chiesi Farmaceutici S.P.A. Combination therapy for COPD
WO2021009573A1 (en) * 2019-07-12 2021-01-21 Kindeva Drug Delivery L.P. Aerosol formulation, canister and inhaler containing the formulation, and method of use
WO2021033081A1 (en) * 2019-08-16 2021-02-25 Glenmark Pharmaceutical Limited Stable aerosol composition for inhalation comprising glycopyrronium, formoterol and corticosteroid
CN112438966B (zh) * 2019-08-30 2022-08-26 四川普锐特药业有限公司 一种医用定量吸入气雾剂
PE20221439A1 (es) 2019-12-02 2022-09-21 Chiesi Farm Spa Lata de acero inoxidable para inhaladores dosificadores presurizados
WO2021138386A1 (en) * 2020-01-04 2021-07-08 Cai Gu Huang Propellant-free formulation for inhalation
CN115003282A (zh) * 2020-01-28 2022-09-02 奇斯药制品公司 包含缓冲药物制剂的加压定量吸入器
EP4106722A1 (en) * 2020-02-20 2022-12-28 Chiesi Farmaceutici S.p.A. Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation
MX2023001201A (es) 2020-07-31 2023-05-03 Chemo Res S L Terapia combinada para la administracion por inhalacion.

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Publication number Priority date Publication date Assignee Title
US20060171899A1 (en) * 1998-12-10 2006-08-03 Akwete Adjei Water-stabilized aerosol formulation system and method of making
DZ3358A1 (fr) * 2000-05-22 2001-11-29 Chiesi Farma Spa Formulations en solution pharmaceutiques pour inhalateurs-doseurs sous pression
US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US20040126325A1 (en) * 2002-03-12 2004-07-01 David Lewis Medicinal aerosol solution formulation products with improved chemical stability
GB0315791D0 (en) * 2003-07-07 2003-08-13 3M Innovative Properties Co Two component molded valve stems
SI1718336T1 (sl) * 2004-02-06 2008-10-31 Meda Pharma Gmbh & Co Kg Nova kombinacija antiholinergika in beta mimetikov za zdravljenje respiratornih bolezni
EP1595531A1 (en) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
WO2005112902A2 (en) 2004-05-13 2005-12-01 Chiesi Farmaceutici S.P.A. Medicinal aerosol formulation products with improved chemical stability
GB0613161D0 (en) * 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
EP2201934A1 (en) * 2008-12-23 2010-06-30 CHIESI FARMACEUTICI S.p.A. Tiotropium aerosol formulation products with improved chemical stability
WO2010144628A2 (en) * 2009-06-09 2010-12-16 Elevation Pharmaceuticals, Inc. Treatment of chronic obstructive pulmonary disease with nebulized beta 2-agonist or combined nebulized beta 2-agonist and anticholinergic administration
NZ600790A (en) * 2009-12-23 2014-09-26 Chiesi Farma Spa Combination therapy for copd
EP2515853B1 (en) 2009-12-23 2014-03-19 Chiesi Farmaceutici S.p.A. Combination therapy for COPD
WO2011076840A2 (en) 2009-12-23 2011-06-30 Chiesi Farmaceutici S.P.A. Aerosol formulation for copd
SG181870A1 (en) * 2009-12-23 2012-07-30 Chiesi Farma Spa Aerosol formulation for copd
SG194896A1 (en) * 2011-05-17 2013-12-30 Pearl Therapeutics Inc Compositions, methods & systems for respiratory delivery of two or more active agents
TR201809356T4 (tr) * 2013-12-30 2018-07-23 Chiesi Farm Spa Gli̇kopi̇ronyum bromür ve formoterol kombi̇nasyonunun stabi̇l basinçli aerosol çözelti̇ kompozi̇syonu.
PL3089735T3 (pl) * 2013-12-30 2018-12-31 Chiesi Farmaceutici S.P.A. Trwała ciśnieniowa kompozycja roztworu aerozolowego kombinacji bromku glikopironium i formoterolu

Also Published As

Publication number Publication date
AR098983A1 (es) 2016-06-22
EP3096737B1 (en) 2018-04-04
CL2016001652A1 (es) 2017-08-25
GEP20186870B (en) 2018-06-25
US20160303044A1 (en) 2016-10-20
CY1120205T1 (el) 2018-12-12
HUE039359T2 (hu) 2018-12-28
PL3096737T3 (pl) 2018-08-31
RS57269B1 (sr) 2018-08-31
KR101865131B1 (ko) 2018-06-08
UA117846C2 (uk) 2018-10-10
CN105848642A (zh) 2016-08-10
AU2014375300B2 (en) 2019-10-24
CA2935302C (en) 2022-06-21
EA033228B1 (ru) 2019-09-30
US10596149B2 (en) 2020-03-24
ES2666905T4 (es) 2018-06-07
PH12016501269B1 (en) 2016-08-15
DK3096737T3 (en) 2018-06-25
MA39154A1 (fr) 2017-08-31
TR201809356T4 (tr) 2018-07-23
JP2017507168A (ja) 2017-03-16
IL246502A0 (en) 2016-08-31
IL246502B (en) 2020-05-31
NZ721640A (en) 2021-02-26
PH12016501269A1 (en) 2016-08-15
JP2019112458A (ja) 2019-07-11
US20170095444A1 (en) 2017-04-06
PT3096737T (pt) 2018-04-27
ES2666905T3 (es) 2018-05-08
SI3096737T1 (en) 2018-07-31
SG11201605309UA (en) 2016-07-28
NO3096737T3 (lt) 2018-09-01
HRP20180944T1 (hr) 2018-08-10
CA2935302A1 (en) 2015-07-09
BR112016014586A2 (pt) 2017-08-08
CN113143894A (zh) 2021-07-23
EA201691127A1 (ru) 2016-12-30
SA516371428B1 (ar) 2018-09-30
MX368834B (es) 2019-10-18
MY176191A (en) 2020-07-24
JP6534397B2 (ja) 2019-06-26
TN2016000262A1 (en) 2017-10-06
KR20160104042A (ko) 2016-09-02
MX2016008591A (es) 2016-09-26
JP6826145B2 (ja) 2021-02-03
WO2015101575A1 (en) 2015-07-09
ME03076B (me) 2019-01-20
PE20161132A1 (es) 2016-11-02
US20150182459A1 (en) 2015-07-02
US10617669B2 (en) 2020-04-14
EP3096737A1 (en) 2016-11-30
AU2014375300A1 (en) 2016-07-14

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