EA200602112A1 - Изделие для медицинского аэрозоля - Google Patents

Изделие для медицинского аэрозоля

Info

Publication number
EA200602112A1
EA200602112A1 EA200602112A EA200602112A EA200602112A1 EA 200602112 A1 EA200602112 A1 EA 200602112A1 EA 200602112 A EA200602112 A EA 200602112A EA 200602112 A EA200602112 A EA 200602112A EA 200602112 A1 EA200602112 A1 EA 200602112A1
Authority
EA
Eurasian Patent Office
Prior art keywords
product
linking agent
butyl rubber
cross
metered dose
Prior art date
Application number
EA200602112A
Other languages
English (en)
Inventor
Брайан Миакин
Дэвид Льюис
Роберт Джонсон
Таня Чарч
Original Assignee
Кьези Фармачеутичи С. П. А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Кьези Фармачеутичи С. П. А. filed Critical Кьези Фармачеутичи С. П. А.
Publication of EA200602112A1 publication Critical patent/EA200602112A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Данное изобретение относится к изделию для медицинского аэрозоля с повышенной химической стабильностью, включающему дозирующий ингалятор под давлением, содержащий контейнер для аэрозоля, снабженный дозирующим клапаном с герметизирующими кольцами и / или прокладками, изготовленными из вулканизата эластомерной композиции, содержащей бутилкаучук, сшивающий агент для бутилкаучука, ускоритель для сшивающего агента, причем ускоритель включает полисульфидное соединение, полученное из замещенной дитиокарбоновой кислоты или ее производного, при этом контейнер содержит состав медицинского аэрозоля, содержащий β-агонист длительного действия, фторуглеводородный пропеллент, сорастворитель и минеральную кислоту в качестве стабилизатора активного ингредиента.
EA200602112A 2004-05-13 2005-02-25 Изделие для медицинского аэрозоля EA200602112A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04011425 2004-05-13
PCT/EP2005/002041 WO2005112902A2 (en) 2004-05-13 2005-02-25 Medicinal aerosol formulation products with improved chemical stability

Publications (1)

Publication Number Publication Date
EA200602112A1 true EA200602112A1 (ru) 2007-04-27

Family

ID=34960892

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200602112A EA200602112A1 (ru) 2004-05-13 2005-02-25 Изделие для медицинского аэрозоля

Country Status (19)

Country Link
US (1) US20070086953A1 (ru)
EP (1) EP1746981B1 (ru)
JP (1) JP2007537170A (ru)
KR (1) KR20070010159A (ru)
CN (1) CN1950075A (ru)
AT (1) ATE404185T1 (ru)
AU (1) AU2005245248A1 (ru)
BR (1) BRPI0510852A (ru)
CA (1) CA2565747A1 (ru)
DE (1) DE602005008946D1 (ru)
EA (1) EA200602112A1 (ru)
ES (1) ES2309722T3 (ru)
IL (1) IL178739A0 (ru)
MA (1) MA28649B1 (ru)
MX (1) MXPA06013189A (ru)
NO (1) NO20065722L (ru)
TN (1) TNSN06334A1 (ru)
WO (1) WO2005112902A2 (ru)
ZA (1) ZA200608742B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA033228B1 (ru) * 2013-12-30 2019-09-30 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Находящаяся под давлением стабильная аэрозольная композиция комбинации гликопиррония бромида и формотерола в форме раствора
AU2014375301B2 (en) * 2013-12-30 2020-03-26 Chiesi Farmaceutici S.P.A. Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination
CN106620976B (zh) * 2016-12-28 2020-01-07 四川普锐特医药科技有限责任公司 一种丙酸氟替卡松定量吸入气雾剂
GB202001537D0 (en) * 2020-02-05 2020-03-18 Consort Medical Plc Pressurised dispensing container
JP2023546025A (ja) * 2020-10-09 2023-11-01 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 加圧定量吸入器のための医薬製剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0015884A (pt) * 2000-05-22 2003-07-08 Chiesi Farma Spa Formulações de soluções farmacêuticas estáveis para inaladores de dose medida pressurizados
US20060257324A1 (en) * 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
MEP30108A (en) * 2002-03-01 2010-06-10 Chiesi Farmaceutici S P Formoterol superfine formulation
US20040126325A1 (en) * 2002-03-12 2004-07-01 David Lewis Medicinal aerosol solution formulation products with improved chemical stability
AU2003214416A1 (en) * 2002-03-18 2003-09-29 Bespak Plc Seal material for a dispensing apparatus
EP1595531A1 (en) * 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
IL177103A0 (en) * 2004-02-27 2006-12-10 Chiesi Farma Spa Stable pharmaceutical solution formulations for pressurized metered dose inhalers
CN101119706B (zh) * 2005-02-25 2013-04-17 奇斯药制品公司 用于加压计量吸入器的包含螯合剂的药物气雾制剂

Also Published As

Publication number Publication date
DE602005008946D1 (de) 2008-09-25
ZA200608742B (en) 2008-07-30
WO2005112902A3 (en) 2006-05-04
WO2005112902A2 (en) 2005-12-01
TNSN06334A1 (en) 2008-02-22
ATE404185T1 (de) 2008-08-15
EP1746981A2 (en) 2007-01-31
EP1746981B1 (en) 2008-08-13
MA28649B1 (fr) 2007-06-01
MXPA06013189A (es) 2007-02-14
NO20065722L (no) 2006-12-12
BRPI0510852A (pt) 2007-11-27
CN1950075A (zh) 2007-04-18
JP2007537170A (ja) 2007-12-20
ES2309722T3 (es) 2008-12-16
IL178739A0 (en) 2007-02-11
US20070086953A1 (en) 2007-04-19
KR20070010159A (ko) 2007-01-22
CA2565747A1 (en) 2005-12-01
AU2005245248A1 (en) 2005-12-01

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