LT3064571T - Pluripotentinių kamieninių ląstelių, indikuotų iš mezenchiminių kamieninių ląstelių, diferenciacijos į osteoblastus būdas - Google Patents

Pluripotentinių kamieninių ląstelių, indikuotų iš mezenchiminių kamieninių ląstelių, diferenciacijos į osteoblastus būdas

Info

Publication number
LT3064571T
LT3064571T LTEP13896338.4T LT13896338T LT3064571T LT 3064571 T LT3064571 T LT 3064571T LT 13896338 T LT13896338 T LT 13896338T LT 3064571 T LT3064571 T LT 3064571T
Authority
LT
Lithuania
Prior art keywords
stem cell
osteoblast
differentiating pluripotent
induced
mesenchymal stem
Prior art date
Application number
LTEP13896338.4T
Other languages
English (en)
Inventor
Sang Yeon Lee
Won Ju Jung
Ho Bin Kim
Min Sun Oh
Kye Ho Lee
Original Assignee
Bbhc Co. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bbhc Co. Ltd. filed Critical Bbhc Co. Ltd.
Publication of LT3064571T publication Critical patent/LT3064571T/lt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/76—Undefined extracts from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
    • C12N2506/1369—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from blood-borne mesenchymal stem cells, e.g. MSC from umbilical blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
LTEP13896338.4T 2013-11-01 2013-11-05 Pluripotentinių kamieninių ląstelių, indikuotų iš mezenchiminių kamieninių ląstelių, diferenciacijos į osteoblastus būdas LT3064571T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020130132057A KR101542848B1 (ko) 2013-11-01 2013-11-01 중간엽 줄기세포로부터 유도된 만능 줄기세포를 이용하여 골아세포로 분화시키는 방법
PCT/KR2013/009949 WO2015064803A1 (ko) 2013-11-01 2013-11-05 중간엽 줄기세포로부터 유도된 만능 줄기세포를 이용하여 골아세포로 분화시키는 방법

Publications (1)

Publication Number Publication Date
LT3064571T true LT3064571T (lt) 2020-06-10

Family

ID=53004391

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP13896338.4T LT3064571T (lt) 2013-11-01 2013-11-05 Pluripotentinių kamieninių ląstelių, indikuotų iš mezenchiminių kamieninių ląstelių, diferenciacijos į osteoblastus būdas

Country Status (17)

Country Link
US (1) US10053669B2 (lt)
EP (1) EP3064571B1 (lt)
JP (1) JP6711758B2 (lt)
KR (1) KR101542848B1 (lt)
CN (1) CN105705631B (lt)
AU (1) AU2013403886B2 (lt)
CY (1) CY1122842T1 (lt)
DK (1) DK3064571T3 (lt)
ES (1) ES2773922T3 (lt)
HR (1) HRP20200312T1 (lt)
HU (1) HUE048416T2 (lt)
LT (1) LT3064571T (lt)
PL (1) PL3064571T3 (lt)
PT (1) PT3064571T (lt)
RS (1) RS60112B1 (lt)
SI (1) SI3064571T1 (lt)
WO (1) WO2015064803A1 (lt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS60200B1 (sr) 2013-11-01 2020-06-30 Bbhc Co Ltd Postupak za proizvodnju indukovane pluripotentne matične ćelije iz mezenhimalne matične ćelije i indukovana pluripotentna matična ćelija proizvedena ovim postupkom
KR101699761B1 (ko) * 2014-05-23 2017-01-25 주식회사 비비에이치씨 플로로탄닌 분획물을 이용한 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하는 방법
CN105802906A (zh) * 2016-05-27 2016-07-27 中国医学科学院医学生物学研究所 树鼩骨髓间充质干细胞成骨诱导分化培养基及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100449141B1 (ko) * 2001-04-19 2004-09-21 (주)라이프코드 간엽 간세포를 신경세포로 분화시키는 방법
WO2006123699A1 (ja) * 2005-05-17 2006-11-23 Kyowa Hakko Kogyo Co., Ltd. 幹細胞に対する骨芽細胞への分化促進剤
US20100135970A1 (en) 2006-10-27 2010-06-03 Caritas St. Elizabeth Medical Center Of Boston, In Methods for Reprogramming Adult Somatic Cells and Uses Thereof
KR101016761B1 (ko) 2009-02-26 2011-02-25 부경대학교 산학협력단 피부 미백활성을 갖는 감태 추출물
JP2012210154A (ja) 2009-08-03 2012-11-01 Keio Gijuku 分化細胞由来多能性幹細胞の樹立方法
WO2011037301A1 (ko) * 2009-09-22 2011-03-31 서울대학교병원 성체세포로부터 만능줄기세포를 유도하는 방법 및 그 방법에 의해 제조된 만능줄기세포
JP6263329B2 (ja) 2009-11-24 2018-01-17 ザ ユニバーシティ オブ コネチカット ヒト胚性および人工多能性幹細胞の分化
KR20120002134A (ko) * 2010-06-30 2012-01-05 서울대학교산학협력단 지방 기질 세포의 역분화를 유도하는 방법
KR20120040488A (ko) 2010-10-19 2012-04-27 충남대학교산학협력단 곰피와 감태 추출물 유래의 플로로탄닌을 포함하는 화장품 조성물
KR101309538B1 (ko) * 2010-11-17 2013-09-23 한양대학교 산학협력단 엑콜 화합물을 함유하는 암 줄기세포 성장 억제용 조성물
KR101887956B1 (ko) 2011-08-10 2018-08-13 (주)아모레퍼시픽 효소 처리 감태 추출물을 포함하는 피부 미백용 조성물

Also Published As

Publication number Publication date
EP3064571A1 (en) 2016-09-07
EP3064571B1 (en) 2020-01-22
EP3064571A4 (en) 2017-09-06
WO2015064803A1 (ko) 2015-05-07
US10053669B2 (en) 2018-08-21
PL3064571T3 (pl) 2020-10-05
JP2016536019A (ja) 2016-11-24
US20160257935A1 (en) 2016-09-08
RS60112B1 (sr) 2020-05-29
KR20150050863A (ko) 2015-05-11
PT3064571T (pt) 2020-03-06
SI3064571T1 (sl) 2020-07-31
AU2013403886B2 (en) 2018-04-05
DK3064571T3 (da) 2020-03-16
CN105705631A (zh) 2016-06-22
CY1122842T1 (el) 2021-05-05
ES2773922T3 (es) 2020-07-15
CN105705631B (zh) 2021-08-03
JP6711758B2 (ja) 2020-06-17
KR101542848B1 (ko) 2015-08-10
HUE048416T2 (hu) 2020-07-28
AU2013403886A1 (en) 2016-06-23
HRP20200312T1 (hr) 2020-10-16

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