PL3064571T3 - Sposób różnicowania pluripotentnych komórek macierzystych indukowanych z mezenchymalnych komórek macierzystych w osteoblast - Google Patents
Sposób różnicowania pluripotentnych komórek macierzystych indukowanych z mezenchymalnych komórek macierzystych w osteoblastInfo
- Publication number
- PL3064571T3 PL3064571T3 PL13896338T PL13896338T PL3064571T3 PL 3064571 T3 PL3064571 T3 PL 3064571T3 PL 13896338 T PL13896338 T PL 13896338T PL 13896338 T PL13896338 T PL 13896338T PL 3064571 T3 PL3064571 T3 PL 3064571T3
- Authority
- PL
- Poland
- Prior art keywords
- stem cell
- osteoblast
- differentiating pluripotent
- induced
- mesenchymal stem
- Prior art date
Links
- 210000002901 mesenchymal stem cell Anatomy 0.000 title 1
- 210000000963 osteoblast Anatomy 0.000 title 1
- 210000001778 pluripotent stem cell Anatomy 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/42—Organic phosphate, e.g. beta glycerophosphate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/76—Undefined extracts from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
- C12N2506/1369—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells from blood-borne mesenchymal stem cells, e.g. MSC from umbilical blood
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Developmental Biology & Embryology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Immunology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020130132057A KR101542848B1 (ko) | 2013-11-01 | 2013-11-01 | 중간엽 줄기세포로부터 유도된 만능 줄기세포를 이용하여 골아세포로 분화시키는 방법 |
| PCT/KR2013/009949 WO2015064803A1 (ko) | 2013-11-01 | 2013-11-05 | 중간엽 줄기세포로부터 유도된 만능 줄기세포를 이용하여 골아세포로 분화시키는 방법 |
| EP13896338.4A EP3064571B1 (en) | 2013-11-01 | 2013-11-05 | Method for differentiating pluripotent stem cell induced from mesenchymal stem cell into osteoblast |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3064571T3 true PL3064571T3 (pl) | 2020-10-05 |
Family
ID=53004391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13896338T PL3064571T3 (pl) | 2013-11-01 | 2013-11-05 | Sposób różnicowania pluripotentnych komórek macierzystych indukowanych z mezenchymalnych komórek macierzystych w osteoblast |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US10053669B2 (pl) |
| EP (1) | EP3064571B1 (pl) |
| JP (1) | JP6711758B2 (pl) |
| KR (1) | KR101542848B1 (pl) |
| CN (1) | CN105705631B (pl) |
| AU (1) | AU2013403886B2 (pl) |
| CY (1) | CY1122842T1 (pl) |
| DK (1) | DK3064571T3 (pl) |
| ES (1) | ES2773922T3 (pl) |
| HR (1) | HRP20200312T1 (pl) |
| HU (1) | HUE048416T2 (pl) |
| LT (1) | LT3064571T (pl) |
| PL (1) | PL3064571T3 (pl) |
| PT (1) | PT3064571T (pl) |
| RS (1) | RS60112B1 (pl) |
| SI (1) | SI3064571T1 (pl) |
| SM (1) | SMT202000121T1 (pl) |
| WO (1) | WO2015064803A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105264066B (zh) | 2013-11-01 | 2021-06-11 | 株式会社美合康生 | 由间充质干细胞生产诱导性多能干细胞的方法以及由该方法生产的诱导性多能干细胞 |
| KR101699761B1 (ko) * | 2014-05-23 | 2017-01-25 | 주식회사 비비에이치씨 | 플로로탄닌 분획물을 이용한 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하는 방법 |
| CN105802906A (zh) * | 2016-05-27 | 2016-07-27 | 中国医学科学院医学生物学研究所 | 树鼩骨髓间充质干细胞成骨诱导分化培养基及其制备方法与应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100449141B1 (ko) * | 2001-04-19 | 2004-09-21 | (주)라이프코드 | 간엽 간세포를 신경세포로 분화시키는 방법 |
| WO2006123699A1 (ja) | 2005-05-17 | 2006-11-23 | Kyowa Hakko Kogyo Co., Ltd. | 幹細胞に対する骨芽細胞への分化促進剤 |
| US20100135970A1 (en) | 2006-10-27 | 2010-06-03 | Caritas St. Elizabeth Medical Center Of Boston, In | Methods for Reprogramming Adult Somatic Cells and Uses Thereof |
| KR101016761B1 (ko) | 2009-02-26 | 2011-02-25 | 부경대학교 산학협력단 | 피부 미백활성을 갖는 감태 추출물 |
| JP2012210154A (ja) * | 2009-08-03 | 2012-11-01 | Keio Gijuku | 分化細胞由来多能性幹細胞の樹立方法 |
| WO2011037301A1 (ko) * | 2009-09-22 | 2011-03-31 | 서울대학교병원 | 성체세포로부터 만능줄기세포를 유도하는 방법 및 그 방법에 의해 제조된 만능줄기세포 |
| CA2725728C (en) | 2009-11-24 | 2014-01-28 | University Of Connecticut | Differentiation of human embryonic and induced pluripotent stem cells |
| KR20120002134A (ko) * | 2010-06-30 | 2012-01-05 | 서울대학교산학협력단 | 지방 기질 세포의 역분화를 유도하는 방법 |
| KR20120040488A (ko) | 2010-10-19 | 2012-04-27 | 충남대학교산학협력단 | 곰피와 감태 추출물 유래의 플로로탄닌을 포함하는 화장품 조성물 |
| KR101309538B1 (ko) * | 2010-11-17 | 2013-09-23 | 한양대학교 산학협력단 | 엑콜 화합물을 함유하는 암 줄기세포 성장 억제용 조성물 |
| KR101887956B1 (ko) | 2011-08-10 | 2018-08-13 | (주)아모레퍼시픽 | 효소 처리 감태 추출물을 포함하는 피부 미백용 조성물 |
-
2013
- 2013-11-01 KR KR1020130132057A patent/KR101542848B1/ko active Active
- 2013-11-05 RS RS20200233A patent/RS60112B1/sr unknown
- 2013-11-05 LT LTEP13896338.4T patent/LT3064571T/lt unknown
- 2013-11-05 SM SM20200121T patent/SMT202000121T1/it unknown
- 2013-11-05 HR HRP20200312TT patent/HRP20200312T1/hr unknown
- 2013-11-05 WO PCT/KR2013/009949 patent/WO2015064803A1/ko not_active Ceased
- 2013-11-05 US US15/033,393 patent/US10053669B2/en active Active
- 2013-11-05 DK DK13896338.4T patent/DK3064571T3/da active
- 2013-11-05 EP EP13896338.4A patent/EP3064571B1/en active Active
- 2013-11-05 HU HUE13896338A patent/HUE048416T2/hu unknown
- 2013-11-05 PL PL13896338T patent/PL3064571T3/pl unknown
- 2013-11-05 PT PT138963384T patent/PT3064571T/pt unknown
- 2013-11-05 CN CN201380080661.3A patent/CN105705631B/zh active Active
- 2013-11-05 SI SI201331670T patent/SI3064571T1/sl unknown
- 2013-11-05 AU AU2013403886A patent/AU2013403886B2/en active Active
- 2013-11-05 ES ES13896338T patent/ES2773922T3/es active Active
- 2013-11-05 JP JP2016552368A patent/JP6711758B2/ja active Active
-
2020
- 2020-02-21 CY CY20201100164T patent/CY1122842T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN105705631A (zh) | 2016-06-22 |
| SMT202000121T1 (it) | 2020-07-08 |
| US20160257935A1 (en) | 2016-09-08 |
| KR101542848B1 (ko) | 2015-08-10 |
| EP3064571A4 (en) | 2017-09-06 |
| LT3064571T (lt) | 2020-06-10 |
| KR20150050863A (ko) | 2015-05-11 |
| AU2013403886B2 (en) | 2018-04-05 |
| EP3064571A1 (en) | 2016-09-07 |
| HUE048416T2 (hu) | 2020-07-28 |
| DK3064571T3 (da) | 2020-03-16 |
| AU2013403886A1 (en) | 2016-06-23 |
| RS60112B1 (sr) | 2020-05-29 |
| CY1122842T1 (el) | 2021-05-05 |
| WO2015064803A1 (ko) | 2015-05-07 |
| PT3064571T (pt) | 2020-03-06 |
| EP3064571B1 (en) | 2020-01-22 |
| HRP20200312T1 (hr) | 2020-10-16 |
| ES2773922T3 (es) | 2020-07-15 |
| US10053669B2 (en) | 2018-08-21 |
| JP6711758B2 (ja) | 2020-06-17 |
| SI3064571T1 (sl) | 2020-07-31 |
| CN105705631B (zh) | 2021-08-03 |
| JP2016536019A (ja) | 2016-11-24 |
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